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MarquesCandeias Marco  Candeias Marco

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Candeias Marco  Candeias Marco

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Researcher Number 50750585
Affiliation (Current) 2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help 2016 – 2020: 京都大学, 医学研究科, 講師
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Molecular biology
Keywords
Principal Investigator
IRES / cancer mutation / cancer / p53 protooncogene / delta160p53 / p53 isoform / p53 mRNA / P53 isoform / P53 mRNA / regulatory mRNA … More / GOF mutation / mRNA translation / Cancer mutation / Delta160p53 / p53 / gene / synonymous mutation / bladder cancer / p14HRas / HRas translation / HRas isoform / HRas mRNA / HRas Less
  • Research Projects

    (2 results)
  • Research Products

    (10 results)
  •  Studying and targeting a proto-oncogenic Internal Ribosome Entry Site (IRES) in p53 mRNA that is activated by the most frequent mutations in cancerPrincipal Investigator

    • Principal Investigator
      Candeias Marco
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyoto University
  •  Hotspot Synonymous Cancer Mutations Part 1: Effect on Cap-independent Translation of New HRAS IsoformPrincipal Investigator

    • Principal Investigator
      Candeias Marco
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kyoto University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer2019

    • Author(s)
      Lacerda Rafaela、Menezes Juliane、Candeias Marco M.
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 0 Pages: 117-132

    • DOI

      10.1007/978-3-030-19966-1_6

    • ISBN
      9783030199654, 9783030199661
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07229
  • [Journal Article] Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition2017

    • Author(s)
      Marques-Ramos Ana、Candeias Marco M.、Menezes Juliane、Lacerda Rafaela、Willcocks Margaret、Teixeira Alexandre、Locker Nicolas、Rom?o Lu?sa
    • Journal Title

      RNA

      Volume: 23 Issue: 11 Pages: 1712-1728

    • DOI

      10.1261/rna.063040.117

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21111
  • [Journal Article] Cancer-specific mutations in p53 induce the translation of D160p53 promoting tumorigenesis2016

    • Author(s)
      Marco M Candeias
    • Journal Title

      EMBO reports

      Volume: 17(11) Issue: 11 Pages: 1542-1551

    • DOI

      10.15252/embr.201541956

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21111, KAKENHI-PLANNED-15H05949
  • [Presentation] p53 family, isoforms and ubiquitination in development, inflammation, hypoxia and cancer2020

    • Author(s)
      Marco Candeias
    • Organizer
      MBSJ2020
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07229
  • [Presentation] Translational switch during integrated stress response (ISR) provides oncogenic capability to tumor suppressor p532019

    • Author(s)
      Marco Candeias
    • Organizer
      MBSJ2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07229
  • [Presentation] Common p53 mutations induce IRES-mediated translation of oncogenic shorter p53 isoforms2018

    • Author(s)
      Bruna Pereira, Rafaela Lacerda, M Maria Lopez-Iniesta, Luisa Romao, Marco Candeias
    • Organizer
      22 Reuniao Anual da Sociedade Portuguesa de Genetica Humana
    • Data Source
      KAKENHI-PROJECT-18K07229
  • [Presentation] NEW FUNCTIONS OF P53 MRNA AND PROTEIN ISOFORMS2017

    • Author(s)
      Marco Candeias
    • Organizer
      ConBio2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K21111
  • [Presentation] Regulation of p53 isoforms by IRES2017

    • Author(s)
      Marco Candeias
    • Organizer
      17th international p53 workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21111
  • [Presentation] Regulation of p53 isoforms by IRES2017

    • Author(s)
      Marco Candeias
    • Organizer
      Invited conference at MRC Leicester
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K21111
  • [Presentation] Mutant p53 Functions Depend on Short Isoforms2016

    • Author(s)
      Marco M Candeias
    • Organizer
      39th Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      Pacifico Yokohama
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K21111

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