Hara Hiromasa 原弘真

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HARA HIROMASA 原弘真

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Researcher Number	50751244
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2021: 自治医科大学, 医学部, 講師 2019: 自治医科大学, 医学部, 助教 2015: 自治医科大学, 分子病態治療研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related Except Principal Investigator Laboratory animal science
Keywords	Principal Investigator 無菌 / 感染症 / 免疫不全 / ブタ / 免疫不全モデル / 感染症予防 / 微生物管理 / アイソレーター / 無菌飼育 / SCIDブタ … More Except Principal Investigator … More フォルスコリン / Prdm14遺伝子 / Hex遺伝子 / 生殖寄与能 / 単為発生胚 / ラットES細胞 / FoxN1遺伝子 / CRISPR/Cas法 / 遺伝子ターゲティングベクター / 末梢血T細胞 / GFP / 胸腺 / マウスES細胞 / Foxn1遺伝子 / CRISPR/Cas9法 / CRISPR/Cas9 / 人工ヌクレアーゼ / 臓器欠損 / 胚盤胞補完法 / ノックアウトラット / 異種キメララット / 胚性幹細胞 Less

Establishment of long-term rearing technology for SCID pigs without isolatorsPrincipal Investigator
- Principal Investigator
  
  Hara Hiromasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Jichi Medical University
The production of the organ deficient model using rat pluripotent stem cells, and organ regeneration by blastocyst complementation procedure
- Principal Investigator
  
  HIRABAYASHI MASUMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Institute for Physiological Sciences

All 2021 2019 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system.2016
- Author(s)
  Goto T, Hara H, Nakauchi H, Hochi S, Hirabayashi M.
- Journal Title
  
  Transgenic Research
  
  Volume: 印刷中 Issue: 4 Pages: 533-544
- DOI
  10.1007/s11248-016-9941-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J10751, KAKENHI-PROJECT-25290037
[Journal Article] Rat blastocysts from nuclear injection and time-lagged enucleation and their commitment to embryonic stem cells.2016
- Author(s)
  Hara H, Goto T, Takizawa A, Sanbo M, Jacob HJ, Kobayashi T, Nakauchi H, Hochi S, Hirabayashi M
- Journal Title
  
  Cell. Reprogram.
  
  Volume: 印刷中 Issue: 2 Pages: 108-115
- DOI
  10.1089/cell.2015.0084
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290037
[Journal Article] Knock-in of a histone H2B-tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats.2015
- Author(s)
  GotoT, Kobayashi T, Hara H, Sanbo M, Hochi S, Nakauchi H, Hirabayashi M
- Journal Title
  
  Mol. Reprod. Dev.
  
  Volume: 82 Issue: 12 Pages: 916-917
- DOI
  10.1002/mrd.22584
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290037
[Journal Article] Effect of Leukemia Inhibitory Factor and Forskolin on Establishment of Rat Embryonic Stem Cell Lines2014
- Author(s)
  Hirabayashi M, Goto T, Tamura C, Sanbo M, Hara H, Hochi S.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 60 Issue: 1 Pages: 78-82
- DOI
  10.1262/jrd.2013-109
- NAID
  130003381862
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10439, KAKENHI-PROJECT-25290037
[Journal Article] Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts.2014
- Author(s)
  Hirabayashi M, Goto T, Tamura C, Sanbo M, Hara H, Kato-Itoh M, Sato H, Kobayashi T, Nakaushi H, Hochi S.
- Journal Title
  
  Stem Cells and Development
  
  Volume: VOL.23 Issue: 2 Pages: 107-114
- DOI
  10.1089/scd.2013.0200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10439, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25290037
[Presentation] 無菌ピッグとその応用2021
- Author(s)
  原弘真、花園豊
- Organizer
  第68回日本実験動物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16028
[Presentation] 無菌ピッグとその応用2021
- Author(s)
  原弘真、花園豊
- Organizer
  第68回日本実験動物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16028
[Presentation] SCIDピッグの長期飼育：再生医療・細胞治療評価系の確立をめざして2019
- Author(s)
  原弘真、伊藤拓哉、菱川修司、中野和明、阿部朋行、柴田宏昭、魚崎英毅、渡邊將人、國田智、長嶋比呂志、花園豊
- Organizer
  第46回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16028
[Presentation] CRISPR/Cas9法により作出したFoxN1遺伝子ノックアウトラットの解析2015
- Author(s)
  後藤哲平, 原弘真, 保地眞一, 平林真澄.
- Organizer
  第62回日本実験動物学会
- Place of Presentation
  京都テルサ (京都府京都市)
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25290037
[Presentation] 臓器再生に向けたCRISPR/Cas9法による腎臓欠損ラットの作出2015
- Author(s)
  後藤哲平, 原弘真, 保地眞一, 平林真澄.
- Organizer
  第108回日本繁殖生物学会
- Place of Presentation
  宮崎大学木花キャンパス　　（宮崎県宮崎市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25290037
[Presentation] ドナー核注入後に時間をおいて除核する方法で作製したラットクローン胚盤胞2015
- Author(s)
  原弘真, 滝澤明子, 後藤哲平, 三宝誠, 小林俊寛, 中内啓光, 保地眞一, 平林真澄.
- Organizer
  第108回日本繁殖生物学会
- Place of Presentation
  宮崎大学木花キャンパス　　（宮崎県宮崎市）
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-25290037
[Presentation] Production of cloned rat blastocysts with CAG/Venus-transgenic donor cells and Rosa26-H2B/tdTomato knock-in recipient oocytes.2015
- Author(s)
  Hara H, Takizawa A, Goto A, Sanbo M, Kobayashi T, Nakauchi H, Hochi S, Hirabayashi M.
- Organizer
  The 48th Annual Meeting of the Society for the Study of Reproduction
- Place of Presentation
  Puerto Rico Convention Center (プエルトリコ,U.S.A.)
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290037
[Presentation] 染色体工学技術とケノム編集技術によるヒト化薬物代謝モテル動物の作製2014
- Author(s)
  香月康宏, 小林カオル, 平林真澄, 佐久間哲史, 久世治郎, 阿部智志, 滝口正人, 平松敬, 本間和久, 梶谷尚世, 嵩原昇子, 香月加奈子, 千葉寛, 山本卓, 押村光雄
- Organizer
  第61回日本実験動物学会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-25290037
[Presentation] Effect of leukemia inhibitory factor and forskolin on establishment of rat embryonic stem cell lines.
- Author(s)
  Hara H, Tagiri M, Hirabayashi M, Hochi S.
- Organizer
  The 40th IETS Annual Conference
- Place of Presentation
  John Ascuaga's Nugget Hotel（アメリカ合衆国ネバダ州リノ）
- Data Source
  KAKENHI-PROJECT-25290037

1. HIRABAYASHI MASUMI (20353435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

Hara Hiromasa 原 弘真

HARA HIROMASA 原 弘真

Research Projects

Research Products

Co-Researchers

Establishment of long-term rearing technology for SCID pigs without isolatorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The production of the organ deficient model using rat pluripotent stem cells, and organ regeneration by blastocyst complementation procedure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rat blastocysts from nuclear injection and time-lagged enucleation and their commitment to embryonic stem cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Knock-in of a histone H2B-tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Leukemia Inhibitory Factor and Forskolin on Establishment of Rat Embryonic Stem Cell Lines2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 無菌ピッグとその応用2021

Author(s)

Organizer

Data Source

[Presentation] 無菌ピッグとその応用2021

Author(s)

Organizer

Data Source

[Presentation] SCIDピッグの長期飼育：再生医療・細胞治療評価系の確立をめざして2019

Author(s)

Organizer

Data Source

[Presentation] CRISPR/Cas9法により作出したFoxN1遺伝子ノックアウトラットの解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 臓器再生に向けたCRISPR/Cas9法による腎臓欠損ラットの作出2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ドナー核注入後に時間をおいて除核する方法で作製したラットクローン胚盤胞2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Production of cloned rat blastocysts with CAG/Venus-transgenic donor cells and Rosa26-H2B/tdTomato knock-in recipient oocytes.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Hara Hiromasa 原弘真

HARA HIROMASA 原弘真