KATANO Takahito 片野敬仁

Researcher Number	50768372
Other IDs
Affiliation (based on the past Project Information) *help	2022: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2020: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2019: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2017 – 2018: 名古屋市立大学, 大学院医学研究科, 研究員 2016 – 2017: 名古屋市立大学, 大学院医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 炎症性腸疾患 / KLF / 消化管幹細胞 / 幹細胞 / 線維化 / KLF4 / マクロファージ / 消化器内科学 / ニッチ / 胃腸形質発現 / 筋線維芽細胞 / 大腸腫瘍 / mesenchymal cell … More Except Principal Investigator … More 腸型形質 / 胃型形質 / in vitro三次元培養系 / 幹細胞 / in vitro 三次元培養腺管 / 胃幹細胞 / 長期in vitro 三次元培養系 / 腸管ベーチェット病 / クローン病 / 潰瘍性大腸炎 / 炎症性腸疾患 / in vitro 三次元培養系 Less

転写因子KLFファミリーの機能から紐解く腸管炎症制御と線維化メカニズムPrincipal Investigator
- Principal Investigator
  
  片野敬仁
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
Regulation of intestinal stem cells in inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  Katano Takahito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
The development of in vitro carcinogenesis model, and the elucidation of mechanism of gastric and intestinal phenotypes aiming at the clinical application
- Principal Investigator
  
  MIZOSHITA Tsutomu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
Function of mesenchymal myofibroblast to sustain gastrointestinal stemness and niche factors for epithelial differentiationPrincipal Investigator
- Principal Investigator
  
  KATANO Takahito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University

All 2022 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Protective Effect of Irsogladine against Aspirin-Induced Mucosal Injury in Human Induced Pluripotent Stem Cell-Derived Small Intestine2022
- Author(s)
  Kanno Takuya、Katano Takahito、Ogawa Isamu、Iwao Takahiro、Matsunaga Tamihide、Kataoka Hiromi
- Journal Title
  
  Medicina
  
  Volume: 59 Issue: 1 Pages: 92-92
- DOI
  10.3390/medicina59010092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-22K08082
[Journal Article] Efficacy of transcatheter arterial embolization for first-line treatment of colonic diverticular bleeding with extravasation on contrast-enhanced computed tomography2022
- Author(s)
  Kojima Yuki、Katano Takahito、Shimura Takaya、Shimohira Masashi、Sugiyama Tomoya、Ebi Masahide、Harada Takahito、Yamamoto Yuki、Hirata Yoshikazu、Kataoka Hiromi
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 44 Pages: e31442-e31442
- DOI
  10.1097/md.0000000000031442
- Data Source
  KAKENHI-PROJECT-22K08082
[Journal Article] Interplay among p21Waf1/Cip1, MUSASHI-1 and Kruppel-like factor 4 in activation of Bmi1-CreER reserve intestinal stem cells after gamma radiation-induced injury2020
- Author(s)
  Orzechowska Emilia J.、Katano Takahito、Bialkowska Agnieszka B.、Yang Vincent W.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 18300-18300
- DOI
  10.1038/s41598-020-75171-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15759
[Journal Article] Efficacies of first and second tumor necrosis factor inhibitors in refractory ulcerative colitis patients in real-world practice,2020
- Author(s)
  Marutani, Y., Mizoshita, T., Sugiyama, T., Togawa, S., Katano, T., Yamada, T., Hirata, Y., Kimura, Y., Miyaki, T., Inoue, Y., Suzuki, E., Sasaki, M., and Kataoka, H.
- Journal Title
  
  Indian J Gastroenterol.
  
  Volume: 39 Issue: 6 Pages: 565-575
- DOI
  10.1007/s12664-020-01092-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09355, KAKENHI-PROJECT-18K15759
[Journal Article] KLF4 Regulates Goblet Cell Differentiation in BMI1＋ Reserve Intestinal Stem Cell Lineage during Homeostasis2020
- Author(s)
  Katano Takahito、Bialkowska Agnieszka B.、Yang Vincent W.
- Journal Title
  
  International Journal of Stem Cells
  
  Volume: 13 Issue: 3 Pages: 424-431
- DOI
  10.15283/ijsc20048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15759
[Journal Article] The efficacy of maintenance therapy after remission induction with tacrolimus in ulcerative colitis with and without previous tumor necrosis factor‐α inhibitor.2019
- Author(s)
  Suzuki T, Mizoshita T, Tanida S, Sugimura N, Katano T, Nishie H, Kataoka H.
- Journal Title
  
  JGH open
  
  Volume: in press Issue: 3 Pages: 217-223
- DOI
  10.1002/jgh3.12140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09355
[Journal Article] Adalimumab Dose-Escalation Therapy Is Effective in Refractory Crohn’s Disease Patients with Loss of Response to Adalimumab, Especially in Cases without Previous Infliximab Treatment.2019
- Author(s)
  Suzuki T, Mizoshita T, Sugiyama T, Hirata Y, Kimura Y, Suzuki Y, Yamada T, Tsukamoto H, Mizushima T, Sugimura N, Katano T, Tanida S, Kataoka H, Sasaki M.
- Journal Title
  
  Case Rep Gastroenterol.
  
  Volume: 13 Issue: 1 Pages: 37-49
- DOI
  10.1159/000496453
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09355
[Journal Article] Prospective comparison of preference and efficacy of adalimumab and infliximab for treating ulcerative colitis naive to antitumor necrosis factor therapy2017
- Author(s)
  Mizoshita, T., Katano, T., Tanida, S., Hirano, A., Miyaki, T., Ozeki, K., Suzuki, Y., Sugimura, N., Kataoka, H. & Joh, T.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 96 Issue: 32 Pages: e7800-e7800
- DOI
  10.1097/md.0000000000007800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09355, KAKENHI-PROJECT-26460945
[Journal Article] Adalimumab therapy in a patient with Crohn's disease with a giant pelvic paraganglioma after chemotherapy.2017
- Author(s)
  Mizoshita T, Ando M, Sagawa H, Mori Y, Katano T, Ozeki K, Tanida S, Okamoto Y, Shimura T, Kubota E, Kataoka H, Kamiya T, Joh T.
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: in press Issue: 3 Pages: 250-254
- DOI
  10.1007/s12328-017-0726-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460945, KAKENHI-PROJECT-17K09355
[Journal Article] Ectopic Gastric and Intestinal Phenotypes, Neuroendocrine Cell Differentiation, and SOX2 Expression Correlated With Early Tumor Progression in Colorectal Laterally Spreading Tumors.2016
- Author(s)
  Katano T, Mizoshita T, Tsukamoto H, Nishie H, Inagaki Y, Hayashi N, Nomura S, Ozeki K, Okamoto Y, Shimura T, Mori Y, Kubota E, Tanida S, Kataoka H, Kuno T, Takahashi S, Joh T.
- Journal Title
  
  Clin Colorectal Cancer.
  
  Volume: - Issue: 2 Pages: 141-146
- DOI
  10.1016/j.clcc.2016.09.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19343, KAKENHI-PROJECT-16K19359
[Presentation] ヒトiPS細胞由来腸管上皮を用いた腸管バリア機能の評価2022
- Author(s)
  管野琢也、片野敬仁、片岡洋望
- Organizer
  第３０回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-22K08082
[Presentation] KRUPPEL-LIKE FACTOR 4 MODULATES GOBLET CELL DIFFERENTIATION AND PLAYS A RADIO-PROTECTIVE ROLE IN THE BMI1+ INTESTINAL RESERVE STEM CELL LINEAGE2020
- Author(s)
  Takahito Katano, Emilia J. Orzechowska, Agnieszka B. Bialkowska, Vincent W. Yang
- Organizer
  Digestive Disease Week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15759
[Presentation] 高齢者の炎症性腸疾患に対する生物学的製剤を含めた免疫抑制治療の検討2020
- Author(s)
  鈴木健人、溝下　勤、片野敬仁、尾関啓司、谷田諭史、片岡洋望
- Organizer
  第62回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K09355
[Presentation] KRUPPEL-LIKE FACTOR 4 REGULATES BMI1+ INTESTINAL RESERVE STEM CELLS DURING HOMEOSTASIS AND INJURY2019
- Author(s)
  Takahito Katano, Chang-Kyung Kim, Emilia J. Orzechowska, Agnieszka B. Bialkowska, Vincent W. Yang
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15759
[Presentation] Adalimumab倍量投与を行った難治性クローン病症例での寛解導入効果を含めた臨床的検討2018
- Author(s)
  鈴木健人、溝下勤、谷田諭史、尾関啓司、片野敬仁、市川紘、野尻優、北川美香、稲垣佑祐、岩崎弘靖、田中守、西江裕忠、岡本泰幸、志村貴也、久保田英嗣、片岡洋望、杉山智哉、佐々木誠人、城卓志
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09355
[Presentation] 当院での抗TNF-α抗体製剤（Adalimumab、Infliximab）による腸管ベーチェット病の治療2018
- Author(s)
  溝下　勤、片野敬仁、尾関啓司、谷田諭史、鈴木健人、市川　紘、野尻　優、岩崎弘靖、稲垣佑祐、田中　守、西江裕忠、岡本泰幸、志村貴也、久保田英嗣、片岡洋望、神谷　武、城　卓志
- Organizer
  第14回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-17K09355
[Presentation] Adalimumabへの二次無効を呈したクローン病症例でのAdalimumab倍量投与の有効性の検討2018
- Author(s)
  鈴木健人、溝下　勤、杉山智哉、平田慶和、木村吉秀、鈴木祐香、山田智則、塚本宏延、水島隆史、杉村直美、片野敬仁、尾関啓司、谷田諭史、片岡洋望、佐々木誠人
- Organizer
  第60回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K09355
[Presentation] 抗TNF-α抗体製剤（インフリキシマブ/アダリムマブ）を導入した潰瘍性大腸炎症例での内視鏡的粘膜治癒率の解析を目的とした前向き研究 -薬剤選択理由のアンケート調査を含めて -2017
- Author(s)
  溝下　勤、谷田諭史、平野敦之、宮木知克、片野敬仁、尾関啓司、片岡洋望、城　卓志
- Organizer
  第59回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K09355
[Presentation] 大腸側方発育型腫瘍における悪性化・粘膜下層浸潤予測因子の臨床病理学的検討2017
- Author(s)
  片野敬仁、西江裕忠、尾関啓司、岡本泰幸、溝下　勤、志村貴也、久保田英嗣、片岡洋望、城　卓志
- Organizer
  第２５回日本消化器関連学会週間ＪＤＤＷ２０１７
- Data Source
  KAKENHI-PROJECT-16K19359
[Presentation] Ectopic Gastric Phenotype, Neuroendocrine Cell Differentiation, and CD10 Expression Correlated With Early Tumor Progression in Colorectal Laterally Spreading Tumors.2016
- Author(s)
  Takahito Katano, Tsutomu Mizoshita, Joh T,
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19359
[Presentation] MALTリンパ腫を除く悪性リンパ腫消化管病変の内視鏡像の検討.2016
- Author(s)
  片野敬仁、片岡洋望、城　卓志.
- Organizer
  JDDW2016
- Place of Presentation
  神戸コンベンションセンター (兵庫県、神戸市）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-16K19359

1. MIZOSHITA Tsutomu (40347414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 城卓志 (30231369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 松永民秀 (40209581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TANIDA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 尾関啓司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KATANO Takahito 片野 敬仁

Research Projects

Research Products

Co-Researchers

転写因子KLFファミリーの機能から紐解く腸管炎症制御と線維化メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of intestinal stem cells in inflammatory bowel diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of in vitro carcinogenesis model, and the elucidation of mechanism of gastric and intestinal phenotypes aiming at the clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of mesenchymal myofibroblast to sustain gastrointestinal stemness and niche factors for epithelial differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Protective Effect of Irsogladine against Aspirin-Induced Mucosal Injury in Human Induced Pluripotent Stem Cell-Derived Small Intestine2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of transcatheter arterial embolization for first-line treatment of colonic diverticular bleeding with extravasation on contrast-enhanced computed tomography2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interplay among p21Waf1/Cip1, MUSASHI-1 and Kruppel-like factor 4 in activation of Bmi1-CreER reserve intestinal stem cells after gamma radiation-induced injury2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacies of first and second tumor necrosis factor inhibitors in refractory ulcerative colitis patients in real-world practice,2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KLF4 Regulates Goblet Cell Differentiation in BMI1＋ Reserve Intestinal Stem Cell Lineage during Homeostasis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy of maintenance therapy after remission induction with tacrolimus in ulcerative colitis with and without previous tumor necrosis factor‐α inhibitor.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adalimumab Dose-Escalation Therapy Is Effective in Refractory Crohn’s Disease Patients with Loss of Response to Adalimumab, Especially in Cases without Previous Infliximab Treatment.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prospective comparison of preference and efficacy of adalimumab and infliximab for treating ulcerative colitis naive to antitumor necrosis factor therapy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adalimumab therapy in a patient with Crohn's disease with a giant pelvic paraganglioma after chemotherapy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ectopic Gastric and Intestinal Phenotypes, Neuroendocrine Cell Differentiation, and SOX2 Expression Correlated With Early Tumor Progression in Colorectal Laterally Spreading Tumors.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒトiPS細胞由来腸管上皮を用いた腸管バリア機能の評価2022

Author(s)

KATANO Takahito 片野敬仁