ZHAO CHENGZHU 趙成珠

Researcher Number	50778678
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2022: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator FOP / 進行性骨化性線維異形成症 / フレア・アップ / 間葉系幹細胞 / iPS細胞 / iPSC / iPS 細胞 / 分子病態学 / 治療薬候補化合物 / mTOR … More Except Principal Investigator … More 分化誘導 / 靭帯 / 靱帯再生 / 靱帯節細胞 / ヒトiPS細胞 / 再生医療 / 多能性幹細胞 / 靭帯再生 / 靭帯節細胞 Less

ACVR1変異によるFOP細胞増殖亢進の原因分子の同定と解析Principal Investigator
- Principal Investigator
  
  趙成珠
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
Establishment of induction protocols for a functional syndetome aiming to develop a novel treatment for tendon and ligament regeneration
- Principal Investigator
  
  Ikeya Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyoto University
Mechanism elucidation and drug development of early-stage FOP respond to TGF-b signaling using patient-derived iPSCsPrincipal Investigator
- Principal Investigator
  
  Zhao Chengzhu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
Drug development of fibrodysplasia ossificans progressiva (FOP) focused on constitutive activation of FOP-ACVR1Principal Investigator
- Principal Investigator
  
  ZHAO CHENGZHU
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage2022
- Author(s)
  Kamiya Daisuke、Takenaka-Ninagawa Nana、Motoike Souta、Kajiya Mikihito、Akaboshi Teppei、Zhao Chengzhu、Shibata Mitsuaki、Senda Sho、Toyooka Yayoi、Sakurai Hidetoshi、Kurihara Hidemi、Ikeya Makoto
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 7 Issue: 1 Pages: 47-47
- DOI
  10.1038/s41536-022-00241-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03803, KAKENHI-PROJECT-23K24533
[Journal Article] In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells2021
- Author(s)
  Masayoshi Yoshimatsu, Hiroe Ohnishi, Chengzhu Zhao, Yasuyuki Hayashi, Fumihiko Kuwata, Shinji Kaba, Hideaki Okuyama, Yoshitaka Kawai, Nao Hiwatashi, Yo Kishimoto, Tatsunori Sakamoto, Makoto Ikeya, Koichi Omori
- Journal Title
  
  Stem Cell Research
  
  Volume: 52 Pages: 102233-102233
- DOI
  10.1016/j.scr.2021.102233
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18803, KAKENHI-PROJECT-19K16540
[Journal Article] Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell-derived mesenchymal stem cells promotes peripheral nerve regeneration2020
- Author(s)
  Mitsuzawa S, Zhao C, Ikeguchi R, Aoyama T, Kamiya D, Ando M, Takeuchi H, Akieda S, Nakayama K, Matsuda S, Ikeya M
- Journal Title
  
  Scientific Reports
  
  Volume: 10(1) Issue: 1 Pages: 1-15
- DOI
  10.1038/s41598-020-68745-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16540
[Journal Article] An mTOR Signaling Modulator Suppressed Heterotopic Ossification of?Fibrodysplasia Ossificans Progressiva2018
- Author(s)
  Hino Kyosuke、Zhao Chengzhu、Horigome Kazuhiko、Nishio Megumi、Okanishi Yasue、Nagata Sanae、Komura Shingo、Yamada Yasuhiro、Toguchida Junya、Ohta Akira、Ikeya Makoto
- Journal Title
  
  Stem Cell Reports
  
  Volume: 11 Issue: 5 Pages: 1106-1119
- DOI
  10.1016/j.stemcr.2018.10.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05447, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-17K19725, KAKENHI-PROJECT-17K15617
[Journal Article] Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.2017
- Author(s)
  Hino K, Horigome K, Nishio M, Komura S, Nagata S, Zhao C, Jin Y, Kawakami K, Yamada Y, Ohta A, Toguchida J, Ikeya M.
- Journal Title
  
  J Clin Invest
  
  Volume: 127 Issue: 9 Pages: 3339-3352
- DOI
  10.1172/jci93521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19725, KAKENHI-PROJECT-15H02370, KAKENHI-PROJECT-17K15617
[Presentation] BIO THREE-DIMENSIONAL CONDUIT DEVELOPED FROM HUMAN IPSC–DERIVED MESENCHYMAL STEM CELLS PROMOTES PERIPHERAL NERVE REGENERATION2020
- Author(s)
  Chengzhu Zhao
- Organizer
  ISSCR2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16540
[Presentation] Indirect mTOR Inhibition Attenuates Fibrodysplasia Ossificans Progressiva (FOP) Identified by Using Patient-Derived iPSCs2019
- Author(s)
  Chengzhu Zhao
- Organizer
  ISSCR 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16540
[Presentation] Drug development of fibrodysplasia ossificans progressiva (FOP) focused on constitutive activation of FOP-ACVR12019
- Author(s)
  趙　成珠
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15617
[Presentation] Suppression of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva Models by an mTOR Signaling Modulator2019
- Author(s)
  Chengzhu Zhao
- Organizer
  ASBMR 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16540

1. Ikeya Makoto (20442923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 上谷大介 (30462675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OHTA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 樋渡直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 戸田口淳也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ZHAO CHENGZHU 趙 成珠

Research Projects

Research Products

Co-Researchers

ACVR1変異によるFOP細胞増殖亢進の原因分子の同定と解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of induction protocols for a functional syndetome aiming to develop a novel treatment for tendon and ligament regeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism elucidation and drug development of early-stage FOP respond to TGF-b signaling using patient-derived iPSCsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug development of fibrodysplasia ossificans progressiva (FOP) focused on constitutive activation of FOP-ACVR1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell-derived mesenchymal stem cells promotes peripheral nerve regeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An mTOR Signaling Modulator Suppressed Heterotopic Ossification of?Fibrodysplasia Ossificans Progressiva2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] BIO THREE-DIMENSIONAL CONDUIT DEVELOPED FROM HUMAN IPSC&#8211;DERIVED MESENCHYMAL STEM CELLS PROMOTES PERIPHERAL NERVE REGENERATION2020

Author(s)

Organizer

Data Source

[Presentation] Indirect mTOR Inhibition Attenuates Fibrodysplasia Ossificans Progressiva (FOP) Identified by Using Patient-Derived iPSCs2019

Author(s)

Organizer

Data Source

[Presentation] Drug development of fibrodysplasia ossificans progressiva (FOP) focused on constitutive activation of FOP-ACVR12019

Author(s)

Organizer

Data Source

[Presentation] Suppression of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva Models by an mTOR Signaling Modulator2019

Author(s)

Organizer

Data Source

ZHAO CHENGZHU 趙成珠

[Presentation] BIO THREE-DIMENSIONAL CONDUIT DEVELOPED FROM HUMAN IPSC–DERIVED MESENCHYMAL STEM CELLS PROMOTES PERIPHERAL NERVE REGENERATION2020