Tetsuro Tago 多胡哲郎

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Tago Tetsuro 多胡哲郎

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Researcher Number	50780649
Other IDs	https://orcid.org/0000-0002-9545-0922
Affiliation (Current)	2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2022: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science
Keywords	Principal Investigator 放射性医薬品 / 核医学 / HDAC6 / PET / 分子イメージング / ユビキチン / イメージング / プロテイノパチー

Structural optimization of PET imaging probes for HDAC6 in the brainPrincipal Investigator
- Principal Investigator
  
  多胡哲郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of 18F-labeled tetrahydroquinoline derivatives for HDAC6 PET imagingPrincipal Investigator
- Principal Investigator
  
  Tago Tetsuro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of PET probes for HDAC6 imagingPrincipal Investigator
- Principal Investigator
  
  Tago Tetsuro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of HDAC6 PET imaging probes for proteinopathiesPrincipal Investigator
- Principal Investigator
  
  Tago Tetsuro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Radiation science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Preclinical Evaluation of an 18F-Labeled SW-100 Derivative for PET Imaging of Histone Deacetylase 6 in the Brain2021
- Author(s)
  Tago Tetsuro、Toyohara Jun、Ishii Kenji
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 12 Issue: 4 Pages: 746-755
- DOI
  10.1021/acschemneuro.0c00774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16778, KAKENHI-PROJECT-18K07658
[Journal Article] Metabolic network topology of Alzheimer’s disease and dementia with Lewy bodies generated using fluorodeoxyglucose positron emission tomography.2020
- Author(s)
  Imai M, Tanaka M, SakataM, Wagatsuma K, Tago T, Toyohara J, Sengoku R, Nishina Y, Kanemaru K, Ishibashi K, Murayama S, Ishii K.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 73 Issue: 1 Pages: 197-207
- DOI
  10.3233/jad-190843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09736, KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655
[Journal Article] Mechanical regulation underlies effects of exercise on serotonin-induced signaling in the prefrontal cortex neurons.2020
- Author(s)
  Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Fujita N, Sawada K, Murase S, Watanave M, Sakai T, Yoshikawa Y, Ogata T, Shinohara M, Nagao M, Sawada Y
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 2 Pages: 100874-100874
- DOI
  10.1016/j.isci.2020.100874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0018, KAKENHI-PROJECT-18K07658, KAKENHI-PLANNED-17H06380, KAKENHI-PROJECT-18H04088, KAKENHI-PROJECT-18H02027, KAKENHI-PROJECT-19H03124, KAKENHI-PROJECT-18K15655
[Journal Article] Radiosynthesis and preliminary evaluation of an 18F-labeled tubastatin A analog for PET imaging of histone deacetylase 62020
- Author(s)
  Tago Tetsuro、Toyohara Jun、Ishii Kenji
- Journal Title
  
  Journal of Labelled Compounds and Radiopharmaceuticals
  
  Volume: 63 Issue: 2 Pages: 85-95
- DOI
  10.1002/jlcr.3823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
[Journal Article] Radiosynthesis of 18F-labeled d-allose2019
- Author(s)
  Yamamoto Hiroyuki、Wada Kenji、Toyohara Jun、Tago Tetsuro、Ibaraki Masanobu、Kinoshita Toshibumi、Yamamoto Yuka、Nishiyama Yoshihiro、Kudomi Nobuyuki
- Journal Title
  
  Carbohydrate Research
  
  Volume: 486 Pages: 107827-107827
- DOI
  10.1016/j.carres.2019.107827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
[Journal Article] Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding site2019
- Author(s)
  Tago Tetsuro、Toyohara Jun、Harada Ryuichi、Furumoto Shozo、Okamura Nubuyuki、Kudo Yukitsuka、Takahashi-Fujigasaki Junko、Murayama Shigeo、Ishii Kenji
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 33 Issue: 6 Pages: 1-8
- DOI
  10.1007/s12149-019-01344-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-18H02771
[Journal Article] Monoamine Oxidase B Binding of 18F-THK5351 to Visualize Glioblastoma and Associated Gliosis2019
- Author(s)
  Tago Tetsuro、Toyohara Jun、Sengoku Renpei、Murayama Shigeo、Ishii Kenji
- Journal Title
  
  Clinical Nuclear Medicine
  
  Volume: 44 Issue: 6 Pages: 507-509
- DOI
  10.1097/rlu.0000000000002564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16K09736, KAKENHI-PROJECT-18K07658
[Journal Article] Searching for diagnostic properties of novel fluorine-18-labeled d-allose2019
- Author(s)
  Toyohara Jun、Yamamoto Hiroyuki、Tago Tetsuro
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 33 Issue: 11 Pages: 855-865
- DOI
  10.1007/s12149-019-01398-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
[Journal Article] Correlations of (18)F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.2018
- Author(s)
  Harada R, Furukawa K, et al.
- Journal Title
  
  J Nucl Med
  
  Volume: 59 Issue: 4 Pages: 671-674
- DOI
  10.2967/jnumed.117.197426
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-16K15570, KAKENHI-PROJECT-17K20083, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-16H06621, KAKENHI-PROJECT-16H07486, KAKENHI-PROJECT-15K08127
[Journal Article] Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases2018
- Author(s)
  Tago Tetsuro、Toyohara Jun
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 2 Pages: 300-300
- DOI
  10.3390/molecules23020300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H07486
[Journal Article] Response of cerebral blood flow and blood pressure to dynamic exercise: A study using PET2018
- Author(s)
  Hiura, M., Nariai, T. Muta, A., Sakata, M., Ishibashi, K. Toyohara, J. Wagatsuma, K. Tago, T., Ishii, K. Maehara, T.
- Journal Title
  
  International Journal of Sports Medicine
  
  Volume: 39 Issue: 03 Pages: 181-188
- DOI
  10.1055/s-0043-123647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01841, KAKENHI-PROJECT-16H07486
[Journal Article] Potential Use of 18F-THK5351 PET to Identify Wallerian Degeneration of the Pyramidal Tract Caused by Cerebral Infarction2017
- Author(s)
  Ishibashi Kenji、Kameyama Masashi、Tago Tetsuro、Toyohara Jun、Ishii Kenji
- Journal Title
  
  Clinical Nuclear Medicine
  
  Volume: 42 Issue: 12 Pages: e523-e524
- DOI
  10.1097/rlu.0000000000001868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-16H07486
[Journal Article] ヒストンデアセチラーゼ6のイメージングを目的としたPETプローブの開発2017
- Author(s)
  多胡哲郎、豊原潤、酒井昌成、林薫平、石井賢二
- Journal Title
  
  JSMI Report
  
  Volume: 11 Pages: 25-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] PET用HDAC6イメージングプローブ[18F]FSW-100の自動合成最適化2023
- Author(s)
  多胡哲郎、豊原潤、石井賢二
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K07682
[Presentation] [18F]F-の活性化法2022
- Author(s)
  多胡哲郎
- Organizer
  PET化学ワークショップ2022
- Data Source
  KAKENHI-PROJECT-20K16778
[Presentation] Radiosynthesis and biological evaluation of a nicotinic acid hydroxamate derivative as a radioligand for HDAC6 PET imaging2022
- Author(s)
  Tetsuro Tago, Jun Toyohara, Kenji Ishii
- Organizer
  International Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07682
[Presentation] 新規脳内HDAC6 PETイメージングプローブの開発2022
- Author(s)
  多胡哲郎、豊原潤、石井賢二
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07682
[Presentation] Development of a PET probe for histone deacetylase 6 in the brain2021
- Author(s)
  Tetsuro Tago, Jun Toyohara, Kenji Ishii
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16778
[Presentation] Radiosynthesis and preliminary evaluation of a novel 18F-labeled probe for PET imaging of HDAC6 in the brain2021
- Author(s)
  Tetsuro Tago, Jun Toyohara, Kenji Ishii
- Organizer
  The 11th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16778
[Presentation] 脳内HDAC6 PETイメージングのための18F-標識テトラヒドロキノリン誘導体の開発2020
- Author(s)
  多胡哲郎、豊原潤、石井賢二
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16778
[Presentation] F-182020
- Author(s)
  多胡哲郎
- Organizer
  PET化学ワークショップ
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] A simple SPE purification method for 18F-radiolabeleing: Proof-of-concept study in stilbene amyloid-β ligands with a neopentyl labeling group2019
- Author(s)
  Tago T, Toyohara J, Fujimaki R, Hirano K, Iwai K, Ishibashi K, Tanaka H
- Organizer
  The 23rd International Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] HDAC6イメージングを目的とした18F-標識ツバスタチンA類縁体の標識合成と生物学的評価2019
- Author(s)
  多胡哲郎，豊原潤，石井賢二
- Organizer
  第14回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] F-18化学2019
- Author(s)
  多胡哲郎
- Organizer
  PET化学ワークショップ2019
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] アルツハイマー病イメージングのためのPETプローブ開発2019
- Author(s)
  多胡哲郎
- Organizer
  第35回都市高齢者の健康長寿医療研究会
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] Preliminary biological evaluation of radioligands for PET imaging of histone deacetylase 62018
- Author(s)
  Tago, T., Toyohara, J., Ishii, K
- Organizer
  EANM'18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] Radiosynthesis and preliminary biological evaluation of a 18F-labeled probe for histone deacetylase 6 PET imaging2018
- Author(s)
  Tago, T., Toyohara, J., Ishii, K
- Organizer
  The 10th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15655
[Presentation] Development of PET probes for imaging of histone deacetylase 62017
- Author(s)
  Tetsuro Tago、Kunpei Hayashi、Masanari Sakai、Kenji Ishii、Jun Toyohara
- Organizer
  FASMI 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] Radiosynthesis of carbon-11- and fluorine-18-labeled Tubastatin A derivatives for PET imaging of histone deacetylase 62017
- Author(s)
  Tetsuro Tago、Kunpei Hayashi、Masanari Sakai、Kenji Ishii、Jun Toyohara
- Organizer
  22nd International Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] Development of PET probes for imaging of histone deacetylase 62017
- Author(s)
  多胡哲郎、林薫平、酒井昌成、石井賢二、豊原潤
- Organizer
  第12回日本分子イメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] ヒストンデアセチラーゼ6のPETイメージングを目的とした放射性標識ツバスタチンA誘導体の開発2017
- Author(s)
  多胡哲郎、豊原潤、酒井昌成、林薫平、石井賢二
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] コンフォメーション病のイメージングを目的としたPETプローブ開発2016
- Author(s)
  多胡哲郎
- Organizer
  首都大バイオコンファレンス2016
- Place of Presentation
  首都大学東京（東京・八王子）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-16H07486
[Presentation] 臨床応用を目指したPET薬剤の次世代化2016
- Author(s)
  豊原潤、多胡哲郎、坂田宗之、石橋賢士、我妻慧、石渡喜一、石井賢二
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知・名古屋）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-16H07486

1. TOYOHARA Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 仙石錬平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 篠原正浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 古川勝敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 日浦幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 石井賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 成相直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tetsuro Tago 多胡 哲郎

Tago Tetsuro 多胡 哲郎

Research Projects

Research Products

Co-Researchers

Structural optimization of PET imaging probes for HDAC6 in the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of 18F-labeled tetrahydroquinoline derivatives for HDAC6 PET imagingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of PET probes for HDAC6 imagingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of HDAC6 PET imaging probes for proteinopathiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Preclinical Evaluation of an 18F-Labeled SW-100 Derivative for PET Imaging of Histone Deacetylase 6 in the Brain2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic network topology of Alzheimer’s disease and dementia with Lewy bodies generated using fluorodeoxyglucose positron emission tomography.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanical regulation underlies effects of exercise on serotonin-induced signaling in the prefrontal cortex neurons.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Radiosynthesis and preliminary evaluation of an 18F-labeled tubastatin A analog for PET imaging of histone deacetylase 62020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Radiosynthesis of 18F-labeled d-allose2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding site2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monoamine Oxidase B Binding of 18F-THK5351 to Visualize Glioblastoma and Associated Gliosis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Searching for diagnostic properties of novel fluorine-18-labeled d-allose2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlations of (18)F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response of cerebral blood flow and blood pressure to dynamic exercise: A study using PET2018

Tetsuro Tago 多胡哲郎

Tago Tetsuro 多胡哲郎