Nishinaka Takashi 西中崇

Researcher Number	50786184
Other IDs
Affiliation (Current)	2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2025: 近畿大学, 医学部, 講師 2017 – 2019: 近畿大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 59010:Rehabilitation science-related / Basic Section 56020:Orthopedics-related / Basic Section 47040:Pharmacology-related / Basic Section 48030:Pharmacology-related / Applied health science
Keywords	Principal Investigator 終末糖化産物 / マクロファージ / 炎症性サイトカイン / 食品 / 細胞老化 / Inflammaging / ヒスチジンリッチ糖タンパク質 / STINGシグナル / がん細胞 / 抗腫瘍免疫 … More / 血管擬態 / 自発運動 / 神経再生 / high mobility group box1 / 血小板 / HMGB1 / 血管新生 / 血管内皮細胞 / neurovascular unit / 脳卒中 … More Except Principal Investigator 血管新生 / HRG / 運動介入 / 血管内皮細胞 / ポリリン酸 / 免疫血栓 / PAMP / 敗血症 / 高ヒスチジン糖蛋白質 / 再生、修復促進 / ホメオスタシス / ヒト由来血管内皮細胞株 / 創傷治癒 / TNF / 疼痛 / 変形性膝関節症 / 炎症性メディエーター / IL-33 / IL33 / DAMP / ヒスタミン / 血漿糖タンパク質 / 炎症生サイトカイン / 慢性炎症性疾患 / メディエーター / ホメオダイナミクス / ニッチ / M2 polarization / 造血幹細胞ニッチ / 脳組織ニッチ / HMGB1 / マクロファージ / 血管系幹細胞・前駆細胞 / 微小環境（ニッチ） / 骨髄 / 骨髄血管 / 間葉系細胞 / 血管系幹細胞/前駆細胞 / ニッチ因子 / 生体恒常性 / 臓器連関 / regeneration / FGF2 / 再生修復 / 恒常性 / CD34+骨髄細胞 / 血管性ニッチ / 脳卒中 / 炎症 / 低酸素 / 運動 / 骨髄微小環境（ニッチ） / CD34+ 血球・血管系前駆細胞 Less

新規Anti-PAMPs因子HRGのPAMPs誘発敗血症関連血液血管系細胞応答反応への作用
- Principal Investigator
  
  和氣秀徳
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kindai University
Role of TNF-alpha in knee osteoarthritis pain and analgesic effect of plasma protein HRG
- Principal Investigator
  
  ハティポールオメル・ファルク
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Development of control method for inflammaging by targeting advanced glycation end productsPrincipal Investigator
- Principal Investigator
  
  西中崇
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kindai University
運動介入による再生、修復促進効果の新しい機序の解析研究
- Principal Investigator
  
  高橋英夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kindai University
Homeostatic effect of improvement candidate drug targeting IL-33
- Principal Investigator
  
  Hatipoglu Omer Faruk
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kindai University
Foundational investigation for development of new cancer drug based on blockage of vasculogenic mimicryPrincipal Investigator
- Principal Investigator
  
  Nishinaka Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Basic study of the niche function improvement medicine development that targeted a homeodynamics-related mediator
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Elucidation of mechanism of neurovascular unit remodeling in repair model after strokePrincipal Investigator
- Principal Investigator
  
  Nishinaka Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Exsercise intervation improves bone marrow niche and endothelial progenitor cell defects in stroke
- Principal Investigator
  
  NIWA Atsuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kindai University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells2023
- Author(s)
  Hatipoglu Omer Faruk、Nishinaka Takashi、Nishibori Masahiro、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Yaykasli Kursat Oguz、Wake Hidenori、Takahashi Hideo
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 4 Pages: 177-186
- DOI
  10.1016/j.jphs.2023.02.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15354, KAKENHI-PROJECT-21K06588
[Journal Article] Different modulation of STING/TBK1/IRF3 signaling by advanced glycation end products2023
- Author(s)
  Nishinaka Takashi、Hatipoglu Omer Faruk、Wake Hidenori、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Nishibori Masahiro、Takahashi Hideo
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 750 Pages: 109808-109808
- DOI
  10.1016/j.abb.2023.109808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
[Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023
- Author(s)
  Toyomura Takao、Watanabe Masahiro、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 7 Pages: 5849-5858
- DOI
  10.1007/s11033-023-08509-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701
[Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 71 Issue: 2 Pages: 264-271
- DOI
  10.1002/bab.2538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD362022
- Author(s)
  Nishinaka Takashi、Hatipoglu Omer Faruk、Wake Hidenori、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Nishibori Masahiro、Takahashi Hideo
- Journal Title
  
  Life Sciences
  
  Volume: 310 Pages: 121116-121116
- DOI
  10.1016/j.lfs.2022.121116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
[Journal Article] Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 4 Pages: 2831-2838
- DOI
  10.1007/s11033-021-07096-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Ikegami Ryo、Suwaki Yui、Sada Minami、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 11 Pages: 10499-10507
- DOI
  10.1007/s11033-022-07929-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages2021
- Author(s)
  Kitaura Atsuhiro、Nishinaka Takashi、Hamasaki Shinichi、Hatipoglu Omer Faruk、Wake Hidenori、Nishibori Masahiro、Mori Shuji、Nakao Shinichi、Takahashi Hideo
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 1 Pages: 0245957-0245957
- DOI
  10.1371/journal.pone.0245957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035, KAKENHI-PROJECT-20K17799
[Journal Article] Involvement of multiple scavenger receptors in advanced glycation end product-induced vessel tube formation in endothelial cells2021
- Author(s)
  Yamazaki Yui、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Liu Keyue、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Yoshino Tadashi、Nishibori Masahiro、Takahashi Hideo
- Journal Title
  
  Experimental Cell Research
  
  Volume: 408 Issue: 1 Pages: 112857-112857
- DOI
  10.1016/j.yexcr.2021.112857
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07290, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
[Journal Article] Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition2021
- Author(s)
  Hatipoglu OF, Uctepe E, Opoku G, Wake H, Ikemura K, Ohtsuki T, Inagaki J, Gunduz M, Gunduz E, Watanabe S, Nishinaka T, Takahashi H, Hirohata S.
- Journal Title
  
  Biomed Pharmacother
  
  Volume: 139 Pages: 111633-111633
- DOI
  10.1016/j.biopha.2021.111633
- NAID
  120007099347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11791, KAKENHI-PROJECT-20H00548, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
[Journal Article] A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages.2020
- Author(s)
  Nishinaka T, Mori S, Yamazaki Y, Niwa A, Wake H, Yoshino T, Nishibori M, Takahashi H.
- Journal Title
  
  Diab Vasc Dis Res.
  
  Volume: 17 Issue: 1 Pages: 147916411989697-147916411989697
- DOI
  10.1177/1479164119896975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035
[Journal Article] Alterations of lymphocyte count and platelet volume precede cerebrovascular lesions in stroke-prone spontaneously hypertensive rats2020
- Author(s)
  Nishinaka Takashi、Yamazaki Yui、Niwa Atsuko、Wake Hidenori、Mori Shuji、Yoshino Tadashi、Nishibori Masahiro、Takahashi Hideo
- Journal Title
  
  Biomarkers
  
  Volume: 25 Issue: 3 Pages: 305-313
- DOI
  10.1080/1354750x.2020.1750703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15035
[Journal Article] Effects of Scavenger Receptor-1 Class A Stimulation on Macrophage Morphology and Highly Modified Advanced Glycation End Product-Protein Phagocytosis.2018
- Author(s)
  Hamasaki S, Kobori T, Yamazaki Y, Kitaura A, Niwa A, Nishinaka T, Nishibori M, Mori S, Nakao S, Takahashi H
- Journal Title
  
  Scientific Reports
  
  Volume: ｓ Issue: 1 Pages: 5901-5901
- DOI
  10.1038/s41598-018-24325-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-17K16766, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035
[Journal Article] Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.2018
- Author(s)
  Kobori T, Hamasaki S, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Wake H, Mori S, Yoshino T, Nishibori M, Takahashi H
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 334-334
- DOI
  10.3389/fimmu.2018.00334
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H07272, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K18996, KAKENHI-PROJECT-18K15035
[Presentation] Glycolaldehyde derived advanced glycation end products suppress STING signaling in macrophage2024
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] Glycolaldehyde derived advanced glycation end products suppress STING signaling in macrophage2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] 自然免疫シグナルSTINGの活性制御に対する終末糖化産物の関与2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] Glycolaldehyde由来の終末糖化産物による自然免疫応答の低下作用2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2023
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] ヒスタミンは血管内皮細胞のH1受容体を介して管腔形成を促進する2023
- Author(s)
  ハティポール　オメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] ヒスタミンはEA.hy926血管内皮細胞のH1受容体を介して管腔形成を促進する2023
- Author(s)
  ハティポール　オメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] 高ヒスチジン糖タンパク質は好中球恒常性維持に寄与する多面的機能を有する2023
- Author(s)
  和氣秀徳、森秀治、西堀正洋、西中崇、ハティポールオメルファルク、髙橋英夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] 高ヒスチジン糖タンパク質は好中球恒常性維持に寄与する多面的機能を有する2023
- Author(s)
  和氣秀徳、森秀治、西堀正洋、西中崇、ハティポールオメルファルク、高橋英夫
- Organizer
  第97回日本薬理学会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] 自然免疫シグナルSTINGの活性制御に対する終末糖化産物の関与2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] TNFαはインテグリンα3-β8を介して血管内皮細胞の管腔形成を促進する2023
- Author(s)
  ハティポールオメルファルク、西中崇、和氣秀徳、西堀正洋、渡邊政博、豊村隆男、森秀治、高橋英夫
- Organizer
  第97回日本薬理学会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] TNFαはインテグリンα3-β8を介して血管内皮細胞の管腔形成を促進する2023
- Author(s)
  ハティポールオメルファルク、西中崇、和氣秀徳、西堀正洋、渡邊政博、豊村隆男、森秀治、高橋英夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] Histamine promotes tube formation of human vascular endothelial cells via H1 receptor2023
- Author(s)
  ハティポール　オメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] Histamine promotes tube formation in human vascular endothelial cells(EA.hy926) by acting through the H1 receptor.2023
- Author(s)
  ハティポール　オメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第96 回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 終末糖化産物によるSTINGシグナルの調節はカルボニル化合物の種類や濃度に依存する2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第97回日本薬理学会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] TNFα Promotes Vascular Endothelial Cell Tube Formation via Integrin α3-β82023
- Author(s)
  ハティポール　オメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 終末糖化産物によるSTINGシグナルの調節はカルボニル化合物の種類や濃度に依存する2023
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] 血液系恒常性維持に密接に関与する多機能タンパク2023
- Author(s)
  和氣秀徳、西中崇、ハティポールオメルファルク、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K10465
[Presentation] Effect of advanced glycation end products on STING pathway in macrophage2022
- Author(s)
  Takashi Nishinaka, Omer Faruk Hatipoglu, Hidenori Wake, Masahiro Watanabe, Takao Toyomura, Masahiro Nishibori, Hideo Takahashi
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] ヒスタミンは血管内皮細胞の管腔形成を促進する2022
- Author(s)
  ハティポールオメルファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] Long-term Advanced Glycation End Product 3 (AGE3) Stimulation Reduces Aggrecan and Type II Collagen Production in Human Chondrocytes2022
- Author(s)
  Omer Faruk Hatipoglu, Takashi Nishinaka, Hidenori Wake, Shuji Mori, Masahiro Watanabe, Takao Toyomura, Hideo Takahashi
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 終末糖化産物によるSTINGシグナルの調節2022
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] ヒスチジンに富む糖タンパク質の抗酸化能は、敗血症の病態生理の改善に寄与する2022
- Author(s)
  和氣秀徳、森秀治、西堀正洋、ハティポールオメルファルク、西中崇、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 抑制性DAMPsとしてのリボソーム構成分子RPL9の同定2022
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、西中崇、ハティポールオメルファルク、高橋英夫、西堀正洋、森秀治
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] ヒスタミンは血管内皮細胞の管腔形成を促進する2022
- Author(s)
  ハティポールオメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第37回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 終末糖化産物によるSTINGシグナルの調節2022
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] ヒスタミンは血管内皮細胞の管腔形成を促進する2022
- Author(s)
  ハティポールオメル　ファルク、西中崇、西堀正洋、渡邊政博、豊村隆男、森秀治、和氣秀徳、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] マクロファージにおけるSTING経路に対する終末糖化産物の影響2022
- Author(s)
  西中崇、ハティポールオメルファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、髙橋英夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] 高ヒスチジン糖タンパク質の抗酸化能は敗血症病態改善に寄与する2022
- Author(s)
  和氣秀徳、森秀治、西堀正洋、ハティポールオメルファルク、西中崇、高橋英夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] 血管内皮細胞におけるAGEスカベンジと血管新生2021
- Author(s)
  西中崇、ハティポール　オメル　ファルク、和氣秀徳、森秀治、西堀正洋、高橋英夫
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] ADAMTS5の発現はヒト軟骨肉腫細胞において NF-κβによってアップレギュレートされる2021
- Author(s)
  Omer Faruk Hatipoglu, Bilgic Dilek Gun, Takashi Nishinaka. Hidenori Wake, Satoshi Hirohata, Hideo Takahashi
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 終末糖化産物による LPS－ HMGB1共刺激炎症応答の相乗的活性化作用2021
- Author(s)
  森秀治、渡邊政博、和氣秀徳、西中崇、ハティポールオメルファルク、高橋英夫、西堀正洋、豊村隆男
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] マクロファージによるLPS細胞内取り込みに対する終末糖化産物の影響2021
- Author(s)
  西中崇、北浦淳寛、ハティポールオメルファルク、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] 終末糖化産物による LPS-HMGB1共刺激炎症応答の相乗的活性化作用2021
- Author(s)
  森秀治, 渡邊政博, 和氣秀徳, 西中崇, ハティポールオメルファルク, 高橋英夫, 西堀正洋, 豊村隆男
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] Relationship between AGE scavenging and angiogenesis in endothelial cell2021
- Author(s)
  Takashi Nishinaka, Omer Faruk Hatipoglu, Hidenori Wake, Shuji Mori, Masahiro Nishibori, Hideo Takahashi
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] 敗血症病態改善作用を有する高ヒスチジン糖タンパク質の抗酸化能2021
- Author(s)
  和氣秀徳, 森秀治, 西堀正洋, 西中崇, ハティポールオメルファルク, 高橋英夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06588
[Presentation] 敗血症病態改善作用を有する高ヒスチジン糖タンパク質の抗酸化能2021
- Author(s)
  和氣秀徳、森秀治、西堀正洋、西中崇、ハティポールオメルファルク、高橋英夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] ADAMTS5の発現はヒト軟骨肉腫細胞においてNF-κβによってアップレギュレートされる2021
- Author(s)
  ハティポールオメルファルク、Bilgic Dilek Gun、西中崇、和氣秀徳、廣畑聡、高橋英夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15354
[Presentation] 脳卒中易発症性高血圧ラットにおいて血小板容積とリンパ球数の変化は脳卒中発症を予測するバイオマーカーである2020
- Author(s)
  西中崇,ハティポールオメルファルク, 和氣秀徳, 森秀治, 西堀正洋, 髙橋英夫
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] Molecule X siRNA attenuates bleomycin-induced pulmonary fibrosis2020
- Author(s)
  Omer Faruk Hatipoglu、Ikemura Kentaro、Ohtsuki Takashi、Inagaki Junko、Nishinaka Takashi、Takahashi Hideo、Hirohata Satoshi
- Organizer
  第93回日本生化学会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] 脳卒中易発症性高血圧ラットにおいてリンパ球数と血小板容積の変動は脳卒中症状の発現よりも先行する2020
- Author(s)
  西中崇、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Alterations of lymphocyte count　and　platelet　volume　precede　development　of　stroke-related　symptoms　in　stroke-prone　spontaneously hypertensive rats2020
- Author(s)
  NishinakaT, Niwa A, Wake H, Mori S, Nishibori M, Takahashi H
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] 脳卒中易発症性高血圧ラットにおいてリンパ球数と血小板容積の変動は脳卒中症状の発現よりも先行する2020
- Author(s)
  西中崇、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] FGF signaling promotes bone marrow niche remodeling in post-stroke recovery2019
- Author(s)
  Niwa A, Akahoshi Y, Horiuchi Y, Nishinaka T, Takahashi H
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] マクロファージにおけるscavenger receptors-1 class A を介した終末糖化産物の取り込み2019
- Author(s)
  77.西中崇, 山﨑由衣, 丹羽淳子, 森秀治, 和氣秀徳, 西堀正洋, 髙橋英夫
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] Enhanced M2 polarization of macrophage and angiogenesis by interleukin-182019
- Author(s)
  Takashi Nishinaka, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Shuji Mori, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi
- Organizer
  第9回国際DAMPsとAlarminsシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] Advanced glycation end products の細胞内取り込みによる血管新生の調節機構2019
- Author(s)
  西中崇、山﨑由衣、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] Advanced glycation end products の細胞内取り込みによる血管新生の調節機構2019
- Author(s)
  西中崇、山﨑由衣、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Advanced glycation end products による血管新生促進機序に対するエンドサイトーシスの関与2019
- Author(s)
  山﨑由衣、西中崇、丹羽淳子、森秀治、和氣秀徳、劉克約、西堀正洋、髙橋英夫
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Enhanced M2 polarization of macrophage and angiogenesis by interleukin-182019
- Author(s)
  Takashi Nishinaka, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Shuji Mori,Tadashi Yoshino, Masahiro Nishibori Hideo Takahashi
- Organizer
  第9回国際DAMPs とAlarmins シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Advanced glycation end productsによる血管新生促進機序に対するエンドサイトーシスの関与2019
- Author(s)
  山﨑由衣、西中崇、丹羽淳子、森秀治、和氣秀徳、劉克約、西堀正洋、高橋英夫
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] Exercise intervention improves bone marrow niche and endothelial progenitor cell defects in stroke2018
- Author(s)
  Niwa A, Akahoshi Y, Nishinaka T, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Screening of sulfated polysaccharide and sugar-related compounds as the regulator of advanced glycation end-products by macrophages2018
- Author(s)
  Nishinaka T, Kobori T, Hamasaki S, Kitaura A, Niwa A, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY　(国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Interleukin-18 amplifies M2 polarization of macrophage which leads excessive angiogenesis2018
- Author(s)
  Yamazaki Y, Kobori T, Niwa A, Nishinaka T, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY　(国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Exercise intervation improves bone marrow niche and endothelial progenitor cell defects in stroke.2018
- Author(s)
  Niwa A, Akahoshi Y, Nishinaka T, Kobori T, Takahashi H
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] マクロファージによる終末糖化産物の取り込みに対する硫酸化多糖類の影響2018
- Author(s)
  75.西中崇, 山﨑由衣, 丹羽淳子, 森秀治, 和氣秀徳, 西堀正洋, 髙橋英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K15035
[Presentation] マクロファージによる終末糖化産物の取り込みに対する硫酸化多糖類の影響2018
- Author(s)
  西中　崇、山﨑　由衣、丹羽　淳子、森　秀治、和氣　秀徳、西堀　正洋、髙橋　英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Advanced glycation end products による血管新生促進機序の解明2018
- Author(s)
  山﨑　由衣、西中　崇、丹羽　淳子、森　秀治、和氣　秀徳、西堀　正洋、髙橋　英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] マクロファージによる終末糖化産物の取り込みに対する硫酸化多糖類の影響2018
- Author(s)
  西中崇、山﨑由衣、丹羽淳子、森秀治、和氣秀徳、西堀正洋、髙橋英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Screening of sulfated polysaccharide and sugar-related compounds as the regulator of advanced glycation end-products by macrophage2018
- Author(s)
  Nishinaka T, Kobori T, , Hamasaki S, Kitaura A, Niwa A, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] マクロファージと血管内皮細胞の細胞間相互作用による血管新生促進機構の解析2018
- Author(s)
  小堀　宅郎、濱﨑　真一、北浦　淳寛、山崎　由衣、西中　崇、丹羽　淳子、西堀　正洋、髙橋　英夫
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Visualization of advanced glycatiion end products phagocytosis by macrophages and identification of possible receptor2018
- Author(s)
  Hamasaki S, Kobori T, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY　(国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Intereleukin-18 amplifies M2 polarization of macrophage which leads excessive angiogenesis2018
- Author(s)
  Yamazaki Y, Kobori T, Niwa A, Nishinaka T, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Visualization of advanced glycation end-products phagocytosis by macrophages and identification of possible receptor2018
- Author(s)
  Hamasaki S, Kobori T, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Advanced glycation end products による血管新生促進機序の解明2018
- Author(s)
  山﨑由衣、西中崇、丹羽淳子、森秀治、和氣秀徳、西堀正洋、髙橋英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Exercise intervention improves bone marrow niche and endothelial progenitor cell defects in stroke2018
- Author(s)
  Niwa A, Akahoshi Y, Nishinaka T, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY　(国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881
[Presentation] Screening of sulfated polysaccharide and sugar-related compounds as the regulator of advanced glycation end-products uptake by macrophage.2018
- Author(s)
  Takashi Nishinaka, Takuro Kobori, Yui Yamazaki, Shinichi Hamasaki, Atsuhiro Kitaura, Atsuko Niwa, Shuji Mori, Masahiro Nishibori, Hideo Takahashi
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15035

1. TAKAHASHI Hideo (60335627)

# of Collaborated Projects: 7 results

# of Collaborated Products: 51 results
2. 和氣秀徳 (60570520)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
3. Hatipoglu Omer Faruk (90791765)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
4. NIWA Atsuko (60122082)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. 西田圭一郎 (80284058)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 廣畑聡 (90332791)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 小堀宅郎 (60734697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 西堀正洋 (50135943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. 山崎由衣 (50761970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. WATANABE Shogo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 稲垣純子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishinaka Takashi 西中 崇

Research Projects

Research Products

Co-Researchers

新規Anti-PAMPs因子HRGのPAMPs誘発敗血症関連血液血管系細胞応答反応への作用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of TNF-alpha in knee osteoarthritis pain and analgesic effect of plasma protein HRG

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of control method for inflammaging by targeting advanced glycation end productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動介入による再生、修復促進効果の新しい機序の解析研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Homeostatic effect of improvement candidate drug targeting IL-33

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Foundational investigation for development of new cancer drug based on blockage of vasculogenic mimicryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic study of the niche function improvement medicine development that targeted a homeodynamics-related mediator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanism of neurovascular unit remodeling in repair model after strokePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exsercise intervation improves bone marrow niche and endothelial progenitor cell defects in stroke

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Different modulation of STING/TBK1/IRF3 signaling by advanced glycation end products2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD362022

Author(s)

Nishinaka Takashi 西中崇