Somiya Masaharu 曽宮正晴

Researcher Number	50788974
Other IDs	https://orcid.org/0000-0002-5607-8128
Affiliation (Current)	2025: 大阪大学, 産業科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 産業科学研究所, 准教授 2017 – 2021: 大阪大学, 産業科学研究所, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (II) / Tumor therapeutics / Basic Section 44010:Cell biology-related / Basic Section 90120:Biomaterials-related Except Principal Investigator Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator エクソソーム / 脂質二重膜 / 膜融合タンパク質 / タンパク質デザイン / がん / マクロファージ / 核酸医薬 / 牛乳 / 脂質 / 細胞間情報伝達 … More / 受容体 / 細胞内シグナリング / GPCR / 細胞外小胞 / ソーティング / ベクター / リボスイッチ / DDS / アプタマー / mRNA … More Except Principal Investigator B型肝炎ウイルス / ナノキャリア / 薬物送達 / 薬物送達システム / ナノレベル精密整列化 / 細胞内侵入能 / ステルス能 / 能動的標的能 / 全自動１細胞解析単離装置 / ウイルス / ナノメディシン Less

Computational design of de novo fusogensPrincipal Investigator
- Principal Investigator
  
  曽宮正晴
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Osaka
Deciphering the intercellular signaling via extracellular vesicles by lipid-recognizing GPCRsPrincipal Investigator
- Principal Investigator
  
  Somiya Masaharu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Osaka University
mRNA sorting into exosomes and its application for drug deliveryPrincipal Investigator
- Principal Investigator
  
  Somiya Masaharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Osaka University
核酸搭載エクソソームによる腫瘍関連マクロファージを標的としたがん治療戦略の実証Principal Investigator
- Principal Investigator
  
  曽宮正晴
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Tumor therapeutics
- Research Institution
  Osaka University
Development of Neo-bionanocapsule for Various In Vivo Targets
- Principal Investigator
  
  KURODA SHUN'ICHI
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Osaka University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book Patent

[Book] Methods Molecular Biology 2059 Drug Delivery Systems2020
- Author(s)
  H. Li, M. Somiya, K. Tatematsu, and S. Kuroda
- Total Pages
  316
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18K18386
[Book] エクソソームー生命現象のカギを握る膜小胞―（仮題）2018
- Author(s)
  曽宮正晴
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17J08534
[Book] ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発2018
- Author(s)
  曽宮正晴、黒田俊一
- Publisher
  CMC出版（東京）
- Data Source
  KAKENHI-PROJECT-16H06314
[Book] ドラッグデリバリーシステム－バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発－2018
- Author(s)
  曽宮正晴、黒田俊一
- Publisher
  CMC出版
- Data Source
  KAKENHI-PROJECT-17J08534
[Book] 化学同人CSJカレントレビュー第32号2018
- Author(s)
  曽宮正晴、黒田俊一
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17J08534
[Book] CSJカレントレビュー生命機能にかかわる分子2018
- Author(s)
  曽宮正晴、黒田俊一
- Publisher
  化学同人（京都）
- Data Source
  KAKENHI-PROJECT-16H06314
[Book] 最新DDS技術の先端バイオ医薬品への応用開発―ナノDDS、リポソーム、表面修飾、プロドラッグなどの最新技術と製剤への具体的応用―2017
- Author(s)
  曽宮正晴, 黒田俊一
- Total Pages
  10
- Publisher
  技術情報協会
- ISBN
  9784861046636
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] Polymerized albumin receptor of hepatitis B virus for evading the reticuloendothelial system2021
- Author(s)
  高木くるみ、曽宮正晴、２名、黒田俊一
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Issue: 5 Pages: 408-408
- DOI
  10.3390/ph14050408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-19K05219
[Journal Article] Reporter Gene Assay for Membrane Fusion of Extracellular Vesicles2021
- Author(s)
  Somiya, Masaharu, Shun’ichi Kuroda
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 10 Issue: 13
- DOI
  10.1002/jev2.12171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15790
[Journal Article] Cytoplasmic delivery of small interfering RNA by photoresponsive non-cationic liposomes2021
- Author(s)
  曽宮正晴、２名、黒田俊一
- Journal Title
  
  JDDST
  
  Volume: 63 Pages: 102488-102488
- DOI
  10.1016/j.jddst.2021.102488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-18K18386
[Journal Article] Enhancing antibody-dependent cellular phagocytosis by re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes2021
- Author(s)
  李コウ、曽宮正晴、黒田俊一
- Journal Title
  
  Biomaterials
  
  Volume: 268 Pages: 120601-120601
- DOI
  10.1016/j.biomaterials.2020.120601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-18J21249
[Journal Article] Reporter gene assay for membrane fusion of extracellular vesicles2021
- Author(s)
  Somiya Masaharu、Kuroda Shun’ichi
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.02.16.431359
- Data Source
  KAKENHI-PROJECT-20K15790, KAKENHI-PROJECT-18K18386
[Journal Article] A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells2021
- Author(s)
  藤田和代、１名、曽宮正晴、黒田俊一、日沼州司
- Journal Title
  
  BBA-Mol Cell
  
  Volume: 1868 Issue: 1 Pages: 118859-118859
- DOI
  10.1016/j.bbamcr.2020.118859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles2021
- Author(s)
  Somiya Masaharu、Kuroda Shun’ichi
- Journal Title
  
  Analytical Chemistry
  
  Volume: 93 Issue: 13 Pages: 5612-5620
- DOI
  10.1021/acs.analchem.1c00339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15790, KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-18K18386
[Journal Article] Construction of a Macrophage-Targeting Bio-nanocapsule-Based Nanocarrier2020
- Author(s)
  Hao Li, Masaharu Somiya, Kenji Tatematsu, Shun’ichi Kuroda
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2059 Pages: 299-313
- DOI
  10.1007/978-1-4939-9798-5_16
- ISBN
  9781493997978, 9781493997985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] DDS Nanocarriers Mimicking Early Infection Machinery of Viruses2020
- Author(s)
  Somiya Masaharu、Kuroda Shun'ichi
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 140 Issue: 2 Pages: 147-152
- DOI
  10.1248/yakushi.19-00187-2
- NAID
  130007793379
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2020-02-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18386, KAKENHI-PROJECT-16H06314
[Journal Article] Carrier development for biopharmaceuticals: Bio-nanocapsules based on the early infection machinery of hepatitis B virus2020
- Author(s)
  曽宮正晴、黒田俊一
- Journal Title
  
  Drug Delivery System
  
  Volume: 35 Issue: 1 Pages: 57-63
- DOI
  10.2745/dds.35.57
- NAID
  130007835763
- ISSN
  0913-5006, 1881-2732
- Year and Date
  2020-01-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] Virus-mimicking nanocarriers for the intracellular delivery of therapeutic biomolecules2020
- Author(s)
  Masaharu Somiya, Shun'ichi Kuroda
- Journal Title
  
  Nanomedicine (London)
  
  Volume: 15 Issue: 12 Pages: 1163-1165
- DOI
  10.2217/nnm-2020-0078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-18K18386
[Journal Article] Where does the cargo go?: Solutions to provide experimental support for the “extracellular vesicle cargo transfer hypothesis”2020
- Author(s)
  Somiya Masaharu
- Journal Title
  
  Journal of Cell Communication and Signaling
  
  Volume: - Issue: 2 Pages: 135-146
- DOI
  10.1007/s12079-020-00552-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18386
[Journal Article] Induction of lipid droplets in non-macrophage cells as well as macrophages by liposomes and exosomes2019
- Author(s)
  Fujita K, Somiya M, Kuroda S, Hinuma S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 510 Issue: 1 Pages: 184-190
- DOI
  10.1016/j.bbrc.2019.01.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] A hepatitis B virus-derived human hepatic cell-specific heparin-binding peptide: identification and application to a drug delivery system2019
- Author(s)
  Liu Qiushi、Somiya Masaharu、Iijima Masumi、Tatematsu Kenji、Kuroda Shun'ichi
- Journal Title
  
  Biomaterials Science
  
  Volume: 7 Issue: 1 Pages: 322-335
- DOI
  10.1039/c8bm01134f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-17J06926, KAKENHI-PROJECT-18K18386
[Journal Article] エンベロープウイルスやエクソソームを利用したドラッグデリバリーシステムの開発2019
- Author(s)
  曽宮正晴、黒田俊一
- Journal Title
  
  膜
  
  Volume: 45 Pages: 222-227
- NAID
  130007724564
- Data Source
  KAKENHI-PROJECT-18K18386
[Journal Article] In vivo uterine local gene delivery system using TAT‐displaying bionanocapsules2019
- Author(s)
  Koizumi Kaori、Nakamura Hitomi、Iijima Masumi、Matsuzaki Takashi、Somiya Masaharu、Kumasawa Keiichi、Kimura Tadashi、Kuroda Shun'ichi
- Journal Title
  
  The Journal of Gene Medicine
  
  Volume: 21 Issue: 12
- DOI
  10.1002/jgm.3140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05219, KAKENHI-PROJECT-19K09779, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] Oriented immobilization to nanoparticles enhanced the therapeutic efficacy of antibody drugs2019
- Author(s)
  Iijima M, Araki K, Liu Q, Somiya M, Kuroda S
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 86 Pages: 373-380
- DOI
  10.1016/j.actbio.2019.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314, KAKENHI-PROJECT-17J06926, KAKENHI-PROJECT-19K05219, KAKENHI-PROJECT-16K04888
[Journal Article] Development of a Macrophage-Targeting and Phagocytosis-Inducing Bio-nanocapsule-based Nanocarrier for Drug Delivery2018
- Author(s)
  Li Hao、Tatematsu Kenji、Somiya Masaharu、Iijima Masumi、ichi Kuroda Shun'
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 490 Pages: 155-160
- DOI
  10.1016/j.actbio.2018.04.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07840, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] Biocompatibility of highly purified bovine milk-derived extracellular vesicles2018
- Author(s)
  Somiya Masaharu、Yoshioka Yusuke、Ochiya Takahiro
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 7 Issue: 1 Pages: 1440132-1440132
- DOI
  10.1080/20013078.2018.1440132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J08534
[Journal Article] Low immunogenic bio-nanocapsule based on hepatitis B virus escape mutants2018
- Author(s)
  Jung Joohee、Somiya Masaharu、Jeong Seong-Yun、Choi Eun Kyung、Kuroda Shun’ichi
- Journal Title
  
  Nanomedicine: Nanotechnology, Biology and Medicine
  
  Volume: 14 Issue: 2 Pages: 595-600
- DOI
  10.1016/j.nano.2017.11.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J08534, KAKENHI-PROJECT-16H06314
[Journal Article] CD11c-specific bio-nanocapsule enhances vaccine immunogenicity by targeting immune cells2018
- Author(s)
  Matsuo Hidenori、Somiya Masaharu、Iijima Masumi、Arakawa Takeshi、Kuroda Shun’ichi
- Journal Title
  
  Journal of Nanobiotechnology
  
  Volume: 16 Issue: 1 Pages: 59-59
- DOI
  10.1186/s12951-018-0386-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] Current Progress of Virus-mimicking Nanocarriers for Drug Delivery2017
- Author(s)
  Masaharu Somiya*, Qiushi Liu*, and Shun’ichi Kuroda.
- Journal Title
  
  Nanotheranostics
  
  Volume: 1 Issue: 4 Pages: 415-429
- DOI
  10.7150/ntno.21723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J06926, KAKENHI-PROJECT-17J08534, KAKENHI-PROJECT-16H06314
[Journal Article] Elucidation of the early infection machinery of hepatitis B virus by using bio-nanocapsule2016
- Author(s)
  Liu Qiushi、Somiya Masaharu、Kuroda Shun’ichi
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 22 Issue: 38 Pages: 8489-8489
- DOI
  10.3748/wjg.v22.i38.8489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] Mutational analysis of hepatitis B virus pre-S1 (9-24) fusogenic peptide2016
- Author(s)
  Qiushi Liu, Masaharu Somiya, Naohiko Shimada, Wakako Sakamoto, Nobuo Yoshimoto, Masumi Iijima, Kenji Tatematsu, Tadashi Nakai, Toshihide Okajima, Atsushi Maruyama, Shun'ichi Kuroda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 474 Issue: 2 Pages: 406-412
- DOI
  10.1016/j.bbrc.2016.04.125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] バイオミミック技術による DDS ナノキャリアの開発：B型肝炎ウイルス感染機構に基づくバイオナノカプセルを中心に2016
- Author(s)
  曽宮正晴, 黒田俊一
- Journal Title
  
  ファインケミカル
  
  Volume: 45 Pages: 18-24
- Data Source
  KAKENHI-PROJECT-16H06314
[Journal Article] Cellular uptake of hepatitis B virus envelope L particles is independent of sodium taurocholate cotransporting polypeptide, but dependent on heparan sulfate proteoglycan2016
- Author(s)
  Somiya M, Liu Q, Yoshimoto N, Iijima M, Tatematsu K, Nakai T, Okajima T, Kuroki K, Ueda K, Kuroda S.
- Journal Title
  
  Virology
  
  Volume: 497 Pages: 23-32
- DOI
  10.1016/j.virol.2016.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] 非カチオン性リポソームによる核酸医薬送達法の可能性2016
- Author(s)
  曽宮正晴, 黒田俊一
- Journal Title
  
  Drug Delivery Systems
  
  Volume: 31 Pages: 35-43
- NAID
  130005147214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06314
[Patent] 核酸を内封してなる中性又はアニオン性リポソーム及びその製造方法2016
- Inventor(s)
  黒田俊一、曽宮正晴
- Industrial Property Rights Holder
  黒田俊一、曽宮正晴
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-16H06314
[Presentation] Analysis of intracellular trafficking of extracellular vesicles for cytoplasmic biomacromolecule delivery2022
- Author(s)
  Masaharu Somiya
- Organizer
  The 25th SANKEN International Symposium,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15790
[Presentation] 細胞外小胞の膜融合活性および内包物放出を定量的に評価するアッセイ系の開発2021
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K15790
[Presentation] 細胞外小胞のエンジニアリングによるタンパク質ソーティングの制御と薬物送達への応用2021
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-20K15790
[Presentation] Cargo delivery mechanism of extracellular vesicles; experimental tools to tackle the dogm2021
- Author(s)
  Masaharu Somiya
- Organizer
  SNEV (Student Network on Extracellular Vesicles) 2021 International Virtual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15790
[Presentation] 機能性ペプチドによる細胞質内薬物送達の効率化と評価系の確立2021
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  日本薬学会141会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] Development of quantitative bioassays to study cargo delivery mechanism and efficiency of extracellular vesicles2021
- Author(s)
  Masaharu Somiya
- Organizer
  Hybrid EV Symposium “EXTRACELLULAR VESICLES IN PATHOPHYSIOLOGY”,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15790
[Presentation] 細胞外小胞のレシピエント細胞内での内包物放出を定量化するアッセイ系の開発2020
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  第７回日本細胞外小胞学会JSEV学術集会
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] Development of extracellular vesicle-based drug delivery systems by cellular engineering2020
- Author(s)
  Masaharu Somiya, Shun’ichi Kuroda
- Organizer
  JAACT2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] エンベロープウイルスやエクソソームを利用したドラッグデリバリーシステムの開発2019
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  日本膜学会第41年会会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] Extracellular vesicles for the delivery of therapeutic biomolecules2019
- Author(s)
  Masaharu Somiya
- Organizer
  ITU MBG Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] ウイルスやエクソソームを応用した高機能DDS開発の取り組み2019
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  次世代医工学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] ウイルス外皮タンパク質を含む細胞外小胞を利用したドラッグデリバリーシステムの開発2019
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  第6回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] 細胞外小胞エクソソームのRNA送達技術への応用2019
- Author(s)
  曽宮正晴、黒田俊一
- Organizer
  日本癌学会第78回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] 非カチオン性リポソームと光増感剤を利用したsiRNAの細胞質内送達2019
- Author(s)
  曽宮正晴、榮田佳那子、黒田俊一
- Organizer
  第31回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] ウイルス骨格やエクソソームを利用した薬物送達技術の開発2018
- Author(s)
  曽宮正晴
- Organizer
  日本生物工学会・次世代アニマルセルインダストリー研究部会設立記念シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] Characterization of Bovine Milk-Derived Extracellular Vesicles as Delivery System for Therapeutics2018
- Author(s)
  A. Kogure, M. Somiya, Y. Yoshioka, and T. Ochiya
- Organizer
  Annual meeting of International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J08534
[Presentation] Creation and application of hepatitis B virus-mimicking nanoparticle for drug delivery.2018
- Author(s)
  Liu Q, Somiya M, Kuroda S.
- Organizer
  The 21st SANKEN International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06314
[Presentation] 食品中および人工のナノ粒子と細胞との相互作用に関する最新の知見2018
- Author(s)
  曽宮正晴
- Organizer
  佐賀県工業技術センター、技術ワークショップ事業、食品・化粧品の機能性セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K18386
[Presentation] NOVEL HEPARIN-BINDING DOMAIN OF HEPATITIS B VIRUS: APPLICATION TO DRUG DELIVERY SYSTEM.2017
- Author(s)
  Liu Q, Somiya M, Kuroda S.
- Organizer
  Biomaterials International 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06314
[Presentation] Purification and drug delivery application of bovine milk-derived extracellular vesicles2017
- Author(s)
  曽宮正晴、吉岡祐亮、落谷孝広
- Organizer
  第９回日本RNAi研究会/第４回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-17J08534
[Presentation] Analysis of Cell Attachment and Entry of Hepatitis B Virus.2017
- Author(s)
  Liu Q, Somiya M, Kuroda S.
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06314
[Presentation] Bioavailability of bovine milk-derived EVs for drug delivery application2017
- Author(s)
  M. Somiya, Y. Yoshioka, and T. Ochiya
- Organizer
  Annual meeting of International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J08534
[Presentation] 生体分子 Exosome による新規核酸送達技術の開発2017
- Author(s)
  吉岡祐亮、曽宮正晴、落谷孝広
- Organizer
  日本薬物動態学会第32回年会
- Invited
- Data Source
  KAKENHI-PROJECT-17J08534
[Presentation] ドラッグデリバリーシステムにおけるミルク由来エクソソームの可能性2017
- Author(s)
  渡邉大裕、藤木純平、井上博紀、樋口豪紀、岩崎智仁、曽宮正晴、吉岡祐亮、落谷孝広、山口昭博、山口さより、平敏夫、岩野英知
- Organizer
  第９回日本RNAi研究会/第４回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-17J08534
[Presentation] Possible involvement of HBV pre-S1 (9-24) fusogenic peptide in uncoating process2016
- Author(s)
  Qiushi Liu, Masaharu Somiya, and Shun’ichi Kuroda
- Organizer
  2016 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06314
[Presentation] Elucidation of early infection machinery of hepatitis B virus and bio-nanocapsule2016
- Author(s)
  Qiushi Liu, Masaharu Somiya, Shun'ichi Kuroda
- Organizer
  e 20th SANKEN International The 15th SANKEN Nanotechnology Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06314

1. KURODA SHUN'ICHI (60263406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
2. 立松健司 (00322743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 飯嶋益巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
4. 良元伸男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Somiya Masaharu 曽宮 正晴

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Co-Researchers

Computational design of de novo fusogensPrincipal Investigator

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Deciphering the intercellular signaling via extracellular vesicles by lipid-recognizing GPCRsPrincipal Investigator

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mRNA sorting into exosomes and its application for drug deliveryPrincipal Investigator

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核酸搭載エクソソームによる腫瘍関連マクロファージを標的としたがん治療戦略の実証Principal Investigator

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Development of Neo-bionanocapsule for Various In Vivo Targets

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[Book] Methods Molecular Biology 2059 Drug Delivery Systems2020

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[Book] エクソソームー生命現象のカギを握る膜小胞―（仮題）2018

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[Book] ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発2018

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[Book] ドラッグデリバリーシステム－バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発－2018

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[Book] 化学同人CSJカレントレビュー第32号2018

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[Book] CSJカレントレビュー 生命機能にかかわる分子2018

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[Book] 最新DDS技術の先端バイオ医薬品への応用開発―ナノDDS、リポソーム、表面修飾、プロドラッグなどの最新技術と製剤への具体的応用―2017

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[Journal Article] Polymerized albumin receptor of hepatitis B virus for evading the reticuloendothelial system2021

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[Journal Article] Reporter Gene Assay for Membrane Fusion of Extracellular Vesicles2021

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[Journal Article] Cytoplasmic delivery of small interfering RNA by photoresponsive non-cationic liposomes2021

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Somiya Masaharu 曽宮正晴

[Book] CSJカレントレビュー生命機能にかかわる分子2018

[Journal Article] エンベロープウイルスやエクソソームを利用したドラッグデリバリーシステムの開発2019