endo akinori 遠藤彬則

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ENDO Akinori 遠藤彬則

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Researcher Number	50796844
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2025: 公益財団法人東京都医学総合研究所, 先端基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2020 – 2022: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員 2018 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Basic Section 43030:Functional biochemistry-related / Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator プロテオミクス / ユビキチン / 定量プロテオーム解析 / ユビキチン創薬 / タンパク質分解 / プロテアソーム / クッシング病 / グルココルチコイド受容体 / 炎症シグナル / エンドソーム / USP8

エンドソームストレス応答によるマクロファージ活性化機構の解析Principal Investigator
- Principal Investigator
  
  遠藤彬則
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Ubiquitin independent proteasomal degradationPrincipal Investigator
- Principal Investigator
  
  ENDO Akinori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
A deubiquitylating enzyme USP8 is required for glucocorticoid receptor activationPrincipal Investigator
- Principal Investigator
  
  ENDO Akinori
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] An attenuated vaccinia vaccine encoding the severe acute respiratory syndrome coronavirus-2 spike protein elicits broad and durable immune responses, and protects cynomolgus macaques and human angiotensin-converting enzyme 2 transgenic mice from severe acute respiratory syndrome coronavirus-2 and its variants.2022
- Author(s)
  Ishigaki H, Yasui F, Nakayama M, Endo A, Yamamoto N, Yamaji K, Nguyen CT, Kitagawa Y, Sanada T, Honda T, Munakata T, Higa M, Toyama S, Kono R, Takagi A, Matsumoto Y, Koseki A, Hayashi K, Shiohara M, Ishii K, Saeki Y, Itoh Y, Kohara M.
- Journal Title
  
  Front Microbiol.
  
  Volume: 13 Pages: 967019-967019
- DOI
  10.3389/fmicb.2022.967019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07531, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-20K08838, KAKENHI-PLANNED-18H05498
[Journal Article] cIAP1-based degraders induce degradation via branched ubiquitin architectures2022
- Author(s)
  Akizuki Yoshino、Morita Mai、Mori Yuki、Kaiho-Soma Ai、Dixit Shivani、Endo Akinori、Shimogawa Marie、Hayashi Gosuke、Naito Mikihiko、Okamoto Akimitsu、Tanaka Keiji、Saeki Yasushi、Ohtake Fumiaki
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 19 Issue: 3 Pages: 311-322
- DOI
  10.1038/s41589-022-01178-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00419, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K19040, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21H02777
[Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021
- Author(s)
  Yokoo Hidetomo、Shibata Norihito、Endo Akinori、Ito Takahito、Yanase Yuta、Murakami Yuki、Fujii Kiyonaga、Hamamura Kengo、Saeki Yasushi、Naito Mikihiko、Aritake Kosuke、Demizu Yosuke
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 21 Pages: 15868-15882
- DOI
  10.1021/acs.jmedchem.1c01206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K07311, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-21K11613, KAKENHI-PROJECT-20K22711
[Presentation] Phase transition of ubiquitylated proteins triggered by ATP depletion2022
- Author(s)
  Akinori Endo
- Organizer
  The 23rd TMIMS International Symposium “New Frontiers in Ubiquitin Proteasome System”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06568
[Presentation] Phase transition of ubiquitylated proteins triggered by ATP depletion2022
- Author(s)
  Akinori Endo
- Organizer
  "Ubiquitin New Frontier from Neo-biology to Targeted Protein Degradation"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06568
[Presentation] 細胞内ATPレベル低下によるユビキチン・プロテアソーム液滴の形成機構2021
- Author(s)
  遠藤彬則、田中啓二、佐伯泰
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06568
[Presentation] ユビキチン非依存性プロテアソーム基質の解析2021
- Author(s)
  佐久間海帆、遠藤彬則、千葉和義、田中啓二、佐伯泰
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06568
[Presentation] RAD23B drives polyubiquitin chain-dependent phase separation of the proteasome2020
- Author(s)
  遠藤彬則
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06568
[Presentation] 脱ユビキチン化酵素USP8によるエンドソームストレス制御2019
- Author(s)
  遠藤彬則
- Organizer
  第19回日本蛋白質科学会年会第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-18K14623
[Presentation] 脱ユビキチン化酵素USP8によるエンドソームストレス制御2019
- Author(s)
  遠藤　彬則
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-18K14623
[Presentation] 脱ユビキチン化酵素USP8によるエンドソーム機能性維持を介した新規細胞間シグナル伝達制御機構2018
- Author(s)
  遠藤　彬則
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K14623

1. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 棟方翼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

endo akinori 遠藤 彬則

ENDO Akinori 遠藤 彬則

Research Projects

Research Products

Co-Researchers

エンドソームストレス応答によるマクロファージ活性化機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ubiquitin independent proteasomal degradationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A deubiquitylating enzyme USP8 is required for glucocorticoid receptor activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Author(s)

Journal Title

DOI

Data Source

[Journal Article] cIAP1-based degraders induce degradation via branched ubiquitin architectures2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Phase transition of ubiquitylated proteins triggered by ATP depletion2022

Author(s)

Organizer

Data Source

[Presentation] Phase transition of ubiquitylated proteins triggered by ATP depletion2022

Author(s)

Organizer

Data Source

[Presentation] 細胞内ATPレベル低下によるユビキチン・プロテアソーム液滴の形成機構2021

Author(s)

Organizer

Data Source

[Presentation] ユビキチン非依存性プロテアソーム基質の解析2021

Author(s)

Organizer

Data Source

[Presentation] RAD23B drives polyubiquitin chain-dependent phase separation of the proteasome2020

Author(s)

Organizer

Data Source

[Presentation] 脱ユビキチン化酵素USP8によるエンドソームストレス制御2019

Author(s)

Organizer

Data Source

[Presentation] 脱ユビキチン化酵素USP8によるエンドソームストレス制御2019

Author(s)

Organizer

Data Source

[Presentation] 脱ユビキチン化酵素USP8によるエンドソーム機能性維持を介した新規細胞間シグナル伝達制御機構2018

Author(s)

Organizer

Data Source

endo akinori 遠藤彬則

ENDO Akinori 遠藤彬則