Okabe Kazuto 岡部一登

Researcher Number	50801453
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 講師
Affiliation (based on the past Project Information) *help	2023: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2020 – 2023: 名古屋大学, 医学系研究科, 助教 2017 – 2020: 名古屋大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Dental engineering/Regenerative dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator エクソソーム / 放射線性顎骨壊死 / 歯髄幹細胞 / 酸素環境 / 骨髄由来間葉系幹細胞 / 再生医療 / ビスホスホネート関連顎骨壊死 Except Principal Investigator 再生医学 / 組織再生 / 再生医療

最適化したエクソソームによる放射線顎骨壊死に対する治療法の開発Principal Investigator
- Principal Investigator
  
  岡部一登
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagoya City University
Treatment development and elucidation of mechanism for radiation-induced osteonecrosis of the jaw with exosomesPrincipal Investigator
- Principal Investigator
  
  Okabe Kazuto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagoya University
Cascaded bone regeneration method with extracellular vesicles prepared for different purposes under variable culture environment
- Principal Investigator
  
  Hibi Hideharu
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagoya University
Development of a treatment for bisphosphonate-related osteonecrosis of the jaw using dental pulp stem cell-derived exosomesPrincipal Investigator
- Principal Investigator
  
  Okabe Kazuto
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] Infected bone substitute after the bone augmentation in the maxilla: A case report2021
- Author(s)
  Kazuto Okabe, Akira Sayo, Yuya Ohta, Go Ohara, Noriyuki Yamamoto, Hideharu Hibi
- Total Pages
  54
- Publisher
  Japanese Stomatological Society
- ISBN
  9784990823733
- Data Source
  KAKENHI-PROJECT-19K10264
[Book] Oral Science in Japan 20202020
- Author(s)
  Kazuto Okabe, Akira Sayo, Yuya Ohta, Go Ohara, Noriyuki Yamamoto, Hideharu Hibi
- Total Pages
  54
- Publisher
  Japanese stmatological society
- ISBN
  9784990823733
- Data Source
  KAKENHI-PROJECT-19K10264
[Journal Article] Hyperthermia maintains death receptor expression and promotes TRAIL‐induced apoptosis2023
- Author(s)
  Ohara Go、Okabe Kazuto、Toyama Naoto、Ohta Yuya、Xinman Song、Ichimura Norihisa、Sato Kotaro、Urata Yusuke、Hibi Hideharu
- Journal Title
  
  Journal of Oral Pathology & Medicine
  
  Volume: 52 Issue: 8 Pages: 718-726
- DOI
  10.1111/jop.13457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10110, KAKENHI-PROJECT-21K17020, KAKENHI-PROJECT-19H03851
[Journal Article] Family with sequence similarity 20 member B regulates osteogenic differentiation of bone marrow mesenchymal stem cells on titanium surfaces2023
- Author(s)
  Song Xinman、Okabe Kazuto、Ohta Yuya、Ohara Go、Toyama Naoto、Chang Qi、Wang Yilin、Hibi Hideharu
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 161 Pages: 298-308
- DOI
  10.1016/j.actbio.2023.02.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17020, KAKENHI-PROJECT-19H03851
[Journal Article] A case involving tooth extraction in a patient with acquired von Willebrand syndrome2021
- Author(s)
  SAWAKI Tadashi、OKABE Kazuto、SAKAGUCHI Kohei、SAKAKURA Hiroki、KANEKO Ryuji、HIBI Hideharu
- Journal Title
  
  Japanese Journal of Oral and Maxillofacial Surgery
  
  Volume: 67 Issue: 7 Pages: 459-463
- DOI
  10.5794/jjoms.67.459
- NAID
  130008090751
- ISSN
  0021-5163, 2186-1579
- Year and Date
  2021-07-20
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K10264
[Journal Article] Chondroitin-4-sulfate transferase-1 depletion inhibits formation of a proteoglycan-rich layer and alters immunotolerance of bone marrow mesenchymal stem cells on titanium oxide surfaces.2020
- Author(s)
  Kamio H, Tsuchiya S, Kuroda K, Okido M, Okabe K, Ohta Y, Toyama N, Hibi H
- Journal Title
  
  Acta biomaterialia
  
  Volume: 114 Pages: 460-470
- DOI
  10.1016/j.actbio.2020.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10264, KAKENHI-PROJECT-18H01732, KAKENHI-PROJECT-19H03851
[Journal Article] The effect of macrophages on an atmospheric pressure plasma-treated titanium membrane with bone marrow stem cells in a model of guided bone regeneration.2020
- Author(s)
  Toyama N, Tsuchiya S, Kamio H, Okabe K, Kuroda K, Okido M, Hibi H
- Journal Title
  
  Journal of materials science. Materials in medicine
  
  Volume: 31 Issue: 8 Pages: 70-70
- DOI
  10.1007/s10856-020-06412-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10264, KAKENHI-PROJECT-18H01732, KAKENHI-PROJECT-19H03851
[Journal Article] Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol2019
- Author(s)
  Shimizu Shinobu、Tsuchiya Shuhei、Hirakawa Akihiro、Kato Katsuyoshi、Ando Masahiko、Mizuno Masaaki、Osugi Masashi、Okabe Kazuto、Katagiri Wataru、Hibi Hideharu
- Journal Title
  
  BMC Oral Health
  
  Volume: 19 Issue: 1 Pages: 69-69
- DOI
  10.1186/s12903-019-0753-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03851, KAKENHI-PROJECT-17K11802
[Presentation] ヒト歯髄幹細胞由来細胞外小胞は放射線性顎骨壊死の発症を予防する2024
- Author(s)
  小原豪，岡部一登，外山直人，太田優也，渡邊純奈，佐藤康太郎，日比英晴
- Organizer
  第66回日本口腔科学会中部地方部会
- Data Source
  KAKENHI-PROJECT-23K09394
[Presentation] ヒト歯髄幹細胞由来細胞外小胞は放射線性顎骨壊死の発症を予防する2023
- Author(s)
  小原豪、岡部一登、外山直人、太田優也、渡邊純奈、佐藤康太郎、日比英晴
- Organizer
  第66回日本口腔科学会中部地方部会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] ヒト歯髄幹細胞由来細胞外小胞が放射線性顎骨壊死に与える効果2022
- Author(s)
  小原豪，岡部一登，宋しん蔓，渡邊純奈，外山直人，太田優也，小間義朗，日比英晴
- Organizer
  第76回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] ヒト歯髄幹細胞由来細胞外小胞が放射線性顎骨壊死に与える効果2022
- Author(s)
  小原　豪，岡部一登，宋昕蔓, 渡邊純奈，外山直人，太田優也，小間義朗，日比英晴
- Organizer
  第76回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10264
[Presentation] Fam20B depletion inhibits formation of proteoglycan-rich layer and alters calcification ability of bone marrow mesenchymal stem cells on titanium oxide surfaces2021
- Author(s)
  宋昕蔓，岡部一登，神尾尚伸，太田優也，小原豪，外山直人，日比英晴
- Organizer
  第75回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] p53変異頭頸部扁平上皮癌に対するTRAILと温熱療法を併用した治療法2021
- Author(s)
  小原　豪，岡部一登，太田優也，山本憲幸，外山直人，浦田悠輔，日比英晴
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10264
[Presentation] Fam20B depletion inhibits formation of proteoglycan-rich layer and alters calcification ability of bone marrow mesenchymal stem cells on titanium oxide surfaces2021
- Author(s)
  Song Xinman, Kazuto Okabe, Hisanobu Kamio, Yuya Ohta, Go Ohara, Naoto Toyama, Hideharu Hibi
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10264
[Presentation] 温熱療法を併用したTRAILの頭頸部扁平上皮癌に対する抗腫瘍効果2021
- Author(s)
  小原　豪，岡部一登，太田優也，山本憲幸，日比英晴
- Organizer
  第39回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10264
[Presentation] 骨再生についてのわれわれの取り組みの変遷2020
- Author(s)
  岡部一登，藤尾正人，酒井陽，椙村有紀子，坂口晃平，渡邊純奈，日比英晴
- Organizer
  第50回日本口腔インプラント学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] TNF-α刺激歯髄由来間葉系幹細胞はTRAILを介して口腔扁平上皮癌を抑制する2019
- Author(s)
  太田優也，土屋周平，神尾尚伸，岡部一登，日比英晴
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] 伸展刺激下で得た細胞培養上清における骨形成・血管新生能の検討2019
- Author(s)
  荻須宏太，藤尾正人，土屋周平，岡部一登，外山直人，日比英晴
- Organizer
  第73回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] TNF-α刺激歯根膜由来間葉系幹細胞の頭頸部扁平上皮癌に対する抗腫瘍効果2019
- Author(s)
  小原豪，土屋周平，太田優也，神尾尚伸，岡部一登，日比英晴
- Organizer
  第64回日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] 大気圧プラズマ処理したチタンがマクロファージの極性変化と骨形成に与える影響2019
- Author(s)
  外山直人，土屋周平，黒田健介，藤尾正人，岡部一登，荻須宏太，神尾尚伸，日比英晴
- Organizer
  第64回日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] オッセオインテグレーションを構成するコンドロイチン4硫酸の機能解析2019
- Author(s)
  神尾尚伸，土屋周平，黒田健介，藤尾正人，岡部一登，荻須宏太，外山直人，太田優也，日比英晴
- Organizer
  第64回日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-19H03851
[Presentation] 間葉系幹細胞由来エクソソームを用いたBRONJに対する治療の有効性の検討2018
- Author(s)
  渡邊純奈，酒井陽，岡部一登，椙村有紀子，坂口晃平，鶴田剛士，中道瑛司，日比英晴
- Organizer
  第63回日本口腔外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H06755
[Presentation] Effects of Mesenchymal Stem Cell-derived Exosomes for Rat BRONJ Model2018
- Author(s)
  Watanabe Junna, Sakai Kiyoshi, Okabe Kazuto, Sugimura Yukiko, Sakaguchi Kohei, Tsuruta Takeshi, Hibi Hideharu
- Organizer
  The 96th General Session and exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06755
[Presentation] ビスホスホネート関連顎骨壊死に対する間葉系幹細胞由来エクソソームを用いた治療の可能性2018
- Author(s)
  渡邊純奈, 酒井　陽, 岡部一登, 若山有紀子, 坂口晃平, 鶴田剛士, 日比英晴
- Organizer
  第72回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-17H06755

1. 酒井陽 (80772425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Hibi Hideharu (90345885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 黒田健介 (00283408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 藤尾正人 (90612804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 興戸正純 (50126843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 土屋周平 (20569785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 市村典久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 外山直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okabe Kazuto 岡部 一登

Research Projects

Research Products

Co-Researchers

最適化したエクソソームによる放射線顎骨壊死に対する治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment development and elucidation of mechanism for radiation-induced osteonecrosis of the jaw with exosomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cascaded bone regeneration method with extracellular vesicles prepared for different purposes under variable culture environment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a treatment for bisphosphonate-related osteonecrosis of the jaw using dental pulp stem cell-derived exosomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Infected bone substitute after the bone augmentation in the maxilla: A case report2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Oral Science in Japan 20202020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Hyperthermia maintains death receptor expression and promotes TRAIL‐induced apoptosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Family with sequence similarity 20 member B regulates osteogenic differentiation of bone marrow mesenchymal stem cells on titanium surfaces2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case involving tooth extraction in a patient with acquired von Willebrand syndrome2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Chondroitin-4-sulfate transferase-1 depletion inhibits formation of a proteoglycan-rich layer and alters immunotolerance of bone marrow mesenchymal stem cells on titanium oxide surfaces.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of macrophages on an atmospheric pressure plasma-treated titanium membrane with bone marrow stem cells in a model of guided bone regeneration.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒト歯髄幹細胞由来細胞外小胞は放射線性顎骨壊死の発症を予防する2024

Author(s)

Organizer

Data Source

[Presentation] ヒト歯髄幹細胞由来細胞外小胞は放射線性顎骨壊死の発症を予防する2023

Author(s)

Okabe Kazuto 岡部一登