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Yamaguchi Akinori  山口 晃巨

ORCIDConnect your ORCID iD *help
Researcher Number 50822087
Other IDs
Affiliation (Current) 2025: 科学警察研究所, 法科学第三部, 研究員
Affiliation (based on the past Project Information) *help 2019 – 2024: 科学警察研究所, 法科学第三部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 34020:Analytical chemistry-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Except Principal Investigator
Basic Section 55060:Emergency medicine-related / Basic Section 58040:Forensics medicine-related
Keywords
Principal Investigator
LC-MS/MS / 誘導体化 / ノビチョク / LC-MS / 神経剤 / チロシン / DABCOによる試薬除去 / ペンタフルオロベンジル誘導体化 / ノビチョク加水分解物 / 未知物質の構造推定 … More / 生体試料 / 活性エステル / 縮合剤 / LC/MS / RMPA / 加水分解物 / DABCO / リン酸 / DMTMM … More
Except Principal Investigator
化学剤 / 化学テロ / 神経剤 / 免疫 / コリンエステラーゼ / 解毒剤 / 危機管理 / ルイサイト代謝物 / ヒ素化合物 / LC-ICP-MS / LC-ICP-MS/MS / 神経ガス / 紙デバイス / 化学テロ対策 / 神経剤検知デバイス / 現場検知 / 流体デバイス Less
  • Research Projects

    (6 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (5 People)
  •  Chemical approaches for toxicity assessment and damage minimization of the nerve agent Novichok.

    • Principal Investigator
      宮口 一
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      National Research Institute of Police Science
  •  化学テロ災害被害者の中毒原因特定の研究-免疫学的手法による神経剤特定方法の開発-

    • Principal Investigator
      大森 毅
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      National Research Institute of Police Science
  •  Development of a Novel Derivatization Method for Analysis of Nerve Agent Adducts in Biological SamplesPrincipal Investigator

    • Principal Investigator
      山口 晃巨
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 34020:Analytical chemistry-related
    • Research Institution
      National Research Institute of Police Science
  •  Development of a paper-based fluidic device to detect nerve agents at the site of a chemical terrorism outbreak

    • Principal Investigator
      Miyaguchi Hajime
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      National Research Institute of Police Science
  •  Development of a highly sensitive analytical method for nerve agent degradation products in biological samplesPrincipal Investigator

    • Principal Investigator
      Yamaguchi Akinori
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      National Research Institute of Police Science
  •  LC-ICP-MS/MSによる生体試料中ヒ素代謝物の化学形態別高感度分析法の開発

    • Principal Investigator
      数井 優子
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      National Research Institute of Police Science

All 2023 2022 2021

All Journal Article Presentation Patent

  • [Journal Article] Advances in Derivatization Techniques Enabled by DABCO for Novichok Agent Analysis in Biofluids Using LC-MS2023

    • Author(s)
      Akinori Yamaguchi, Hajime Miyaguchi
    • Journal Title

      Analytical Chemistry

      Volume: 95 Issue: 36 Pages: 13674-13682

    • DOI

      10.1021/acs.analchem.3c02775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K13777
  • [Journal Article] Dimethoxytriadinylation LC-MS/MS of Novichok A-Series Degradation Products in Human Urine2022

    • Author(s)
      Akinori Yamaguchi, Hajime Miyaguchi, Manabu Tokeshi
    • Journal Title

      Analytical Chemistry

      Volume: 94 Issue: 11 Pages: 4658-4665

    • DOI

      10.1021/acs.analchem.1c04634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16364
  • [Journal Article] Analysis of degradation products of Novichok agents in human urine by hydrophilic interaction liquid chromatography-tandem mass spectrometry2022

    • Author(s)
      Otsuka Mai、Yamaguchi Akinori、Miyaguchi Hajime
    • Journal Title

      Forensic Toxicology

      Volume: - Issue: 2 Pages: 0-0

    • DOI

      10.1007/s11419-022-00656-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K18990, KAKENHI-PROJECT-19K16364
  • [Journal Article] Paper-Based Analytical Device for the On-Site Detection of Nerve Agents2021

    • Author(s)
      Yamaguchi Akinori、Miyaguchi Hajime、Ishida Akihiko、Tokeshi Manabu
    • Journal Title

      ACS Applied Bio Materials

      Volume: 4 Issue: 8 Pages: 6512-6518

    • DOI

      10.1021/acsabm.1c00655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09279, KAKENHI-PROJECT-20H02760
  • [Patent] 検知デバイス2021

    • Inventor(s)
      渡慶次学、石田晃彦、山口晃巨、宮口 一
    • Industrial Property Rights Holder
      国立大学法人北海道大学、警察庁科学警察研究所長
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-100887
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K09279
  • [Presentation] LC-ICP-MS/MSによるルイサイト分解物の分析2023

    • Author(s)
      数井 優子、山口 晃巨、大塚 麻衣、宮口 一
    • Organizer
      日本分析化学会第72年会
    • Data Source
      KAKENHI-PROJECT-19K10701
  • [Presentation] 神経剤A剤(ノビチョク)-ブチリルコリンエステラーゼ付加体からのA剤加水分解物の検出2023

    • Author(s)
      山口 晃巨,宮口 一
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K13777
  • [Presentation] 尿中のルイサイト代謝物と無機ヒ素代謝物の同時分析法の開発2023

    • Author(s)
      大塚麻衣、山口晃巨、宮口一、数井優子
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-19K10701
  • [Presentation] 神経剤ノビチョク分解物のペンタフルオロベンジル誘導体化LC-MS/MS法の開発2023

    • Author(s)
      山口 晃巨,宮口 一
    • Organizer
      日本分析化学会第72年会
    • Data Source
      KAKENHI-PROJECT-23K13777
  • [Presentation] 尿中ルイサイト代謝物のLC-ICP-MS/MSによる分析2023

    • Author(s)
      数井 優子、山口 晃巨、大塚 麻衣、宮口 一
    • Organizer
      日本法科学技術学会第29回学術集会
    • Data Source
      KAKENHI-PROJECT-19K10701
  • [Presentation] ノビチョクを含む神経剤加水分解物のジメトキシトリアジニル (DMT) 誘導体化LC?MS/MS法の開発2022

    • Author(s)
      山口晃巨, 宮口一
    • Organizer
      第29回クロマトグラフィーシンポジウム
    • Data Source
      KAKENHI-PROJECT-19K16364
  • 1.  大塚 麻衣 (90801580)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  Miyaguchi Hajime (10370884)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  数井 優子 (90356197)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  大森 毅 (70356195)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  渡慶次 学 (60311437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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