YAMAGUCHI Yu 山口優

Researcher Number	50823308
Other IDs
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 長崎大学, 医歯薬学総合研究科(歯学系), 助教
Review Section/Research Field	Principal Investigator Basic Section 57010:Oral biological science-related / Basic Section 57020:Oral pathobiological science-related / 0907:Oral science and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57020:Oral pathobiological science-related / Basic Section 57010:Oral biological science-related / Basic Section 57080:Social dentistry-related
Keywords	Principal Investigator Rab GTPase / Rab44 / Rab44ノックアウトマウス / 破骨細胞 / Coro1c / 骨組織・骨代謝解析 / 関節リウマチモデルマウス / Coronin1C / 骨粗鬆症 / 骨組織解析 / カルシウム感受性 … More Except Principal Investigator … More 破骨細胞 / リソソーム / 口腔癌細胞 / Rab44 / 歯周病 / 細胞内輸送 / Rufy4 / 骨吸収 / Rab / 代謝性骨疾患 / 細胞外小胞 / TurboID / 質量分析 / カテプシンK / マルチモーダルイメージング / TRPV4 / マウス / 口腔上皮 / 歯肉 / 細胞移動 / メカノセンサー / TRPチャネル / イオンチャネル / 付着上皮 / 上皮 / 細胞内小胞輸送 / 免疫細胞 / 関節リウマチ / 炎症性骨破壊疾患 / 波状縁 / カテプシンＤ / LAMP1 / カテプシンＫ / タンパク分解 / FYVE / RUN / Rab7 / 酸化ストレス / オートファジー Less

小胞輸送系分子を基軸とする関節リウマチモデルマウスの病態解明Principal Investigator
- Principal Investigator
  
  山口優
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Imaging analysis of the dynamics of lysosomal membranes involved in the acidic environment of oral cancer cells
- Principal Investigator
  
  角忠輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
変異型Rufy4を発現する破骨細胞の細胞外小胞を介した骨吸収調節機構の解明と応用
- Principal Investigator
  
  坂井詠子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Functional analysis of a novel membrane transport factor in metabolic bone diseases
- Principal Investigator
  
  福間裕
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Nagasaki University
Elucidating the Pathophysiology of Osteoporosis Model Mice Using Novel Molecules Targeting Membrane Transport SystemsPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Yu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Multimodal imaging analysis of oral cancer cells focused on lysosomes
- Principal Investigator
  
  角忠輝
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Elucidating the regulatory mechanism of osteoclast differentiation of Rab44 and its effects on bone tissuePrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Functional and pathological analyses of inflammatory bone destruction disease by a novel Rab protein
- Principal Investigator
  
  Tsukuba Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Involvement of mechanosensors in periodontal disease
- Principal Investigator
  
  Kido Mizuho
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Saga University
Elucidation of the function of novel autophagy regulators related to oxidative stress and bone resorption
- Principal Investigator
  
  Sakai Eiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Molecular mechanism of Rab44 regulation of osteoclast differentiation and function elucidation in vivo.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Yu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Nagasaki University

All 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] Studies in Natural Products Chemistry2022
- Author(s)
  Eiko Sakai, Fatima Farhana, Yu Yamaguchi, Takayuki Tsukuba
- Total Pages
  481
- Publisher
  ELSEVIER
- ISBN
  9780128239445
- Data Source
  KAKENHI-PROJECT-19K10055
[Book] Studies in Natural Products Chemistry2021
- Author(s)
  Eiko Sakai, Fatima Farhana, Yu Yamaguchi, and Takayuki Tsukuba
- Total Pages
  49
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-19K10055
[Journal Article] Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy2023
- Author(s)
  Noguromi Mayuko、Yamaguchi Yu、Sato Keiko、Oyakawa Shun、Okamoto Kuniaki、Murata Hiroshi、Tsukuba Takayuki、Kadowaki Tomoko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 2 Pages: 994-994
- DOI
  10.3390/ijms24020994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-22K09942, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09507
[Journal Article] Rab44 negatively regulates myoblast differentiation by controlling fusogenic protein transport and mTORC1 signaling2023
- Author(s)
  Tanimoto Ayuko、Yamaguchi Yu、Kadowaki Tomoko、Sakai Eiko、Oyakawa Shun、Ono Yusuke、Yoshida Noriaki、Tsukuba Takayuki
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 124 Issue: 10 Pages: 1486-1502
- DOI
  10.1002/jcb.30457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09440, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-20K10209, KAKENHI-PROJECT-23K27808
[Journal Article] Abr, a Rho-regulating protein, modulates osteoclastogenesis by enhancing lamellipodia formation by interacting with poly(ADP-ribose) glycohydrolase2023
- Author(s)
  Farhana Fatima、Sakai Eiko、Koyanagi Yu、Yamaguchi Yu、Alam Mohammad Ibtehaz、Okamoto Kuniaki、Tsukuba Takayuki
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 9 Pages: 7557-7569
- DOI
  10.1007/s11033-023-08690-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09152, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-20K09474
[Journal Article] Rab44 deficiency accelerates recovery from muscle damage by regulating mTORC1 signaling and transport of fusogenic regulators2023
- Author(s)
  Oyakawa Shun、Yamaguchi Yu、Kadowaki Tomoko、Sakai Eiko、Noguromi Mayuko、Tanimoto Ayuko、Ono Yusuke、Murata Hiroshi、Tsukuba Takayuki
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 10 Pages: 2253-2266
- DOI
  10.1002/jcp.31082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-23K27808
[Journal Article] Coronin1C is a GDP-specific Rab44 effector that controls osteoclast formation by regulating cell motility in macrophages.2022
- Author(s)
  Yu Yamaguchi, Tomoko Kadowaki, Nozomi Aibara, Kaname Ohyama, Kuniaki Okamoto, Eiko Sakai and Takayuki Tsukuba
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23 Issue: 12 Pages: 6619-6619
- DOI
  10.3390/ijms23126619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-22K17004, KAKENHI-PROJECT-20H03860
[Journal Article] Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit differential localization in mast cells.2021
- Author(s)
  Kadowaki T, Yamaguchi Y, Ogawa K, Tokuhisa M, Okamoto K, Tsukuba T.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Issue: 4 Pages: 1165-1185
- DOI
  10.1002/2211-5463.13133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047
[Journal Article] Large Rab GTPases: Novel Membrane Trafficking Regulators with a Calcium Sensor and Functional Domains2021
- Author(s)
  Tsukuba Takayuki、Yamaguchi Yu、Kadowaki Tomoko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 14 Pages: 7691-7691
- DOI
  10.3390/ijms22147691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047
[Journal Article] The large GTPase Rab44 regulates granule exocytosis in mast cells and IgE-mediated anaphylaxis.2020
- Author(s)
  Kadowaki T, Yamaguchi Y, Kido MA, Abe T, Ogawa K, Tokuhisa M, Gao W, Okamoto K, Kiyonari H, Tsukuba T.
- Journal Title
  
  Cell Mol Immunol.
  
  Volume: 17 Issue: 12 Pages: 1287-1289
- DOI
  10.1038/s41423-020-0413-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-20H03860
[Journal Article] Expression and localisation of Rab44 in immune-related cells change during cell differentiation and stimulation.2020
- Author(s)
  Tokuhisa M., Kadowaki T., Ogawa K., Yamaguchi Y., Kido MA., Gao W., Umeda M., Tsukuba T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 10728-10728
- DOI
  10.1038/s41598-020-67638-7
- NAID
  120006988132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860
[Journal Article] Role of the EF-hand and coiled-coil domains of human Rab44 in localisation and organelle formation.2020
- Author(s)
  Ogawa K, Kadowaki T, Tokuhisa M, Yamaguchi Y, Umeda M, Tsukuba T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 19149-19149
- DOI
  10.1038/s41598-020-75897-7
- NAID
  120006988463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860
[Presentation] Dennd2cは破骨細胞分化を負に制御する2023
- Author(s)
  小栁　悠、坂井　詠子、山口　優、Farhana Fatima、平　曜輔、村田比呂司、筑波　隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K09507
[Presentation] Dennd2cは破骨細胞分化を負に制御する2023
- Author(s)
  小柳悠, 坂井詠子, 山口優，Farhana Fatima, 平　曜輔，村田比呂司, 筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K09152
[Presentation] Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する2023
- Author(s)
  谷本あゆ子、山口優，門脇知子，坂井詠子, 親川駿, 筑波隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44はコラーゲン抗体誘発性関節炎において炎症反応を制御する2023
- Author(s)
  山口　優，門脇　知子，坂井　詠子，野黒美　麻由子，親川　駿, 日浅　匠，馬渡　遥香，筑波　隆幸
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K09507
[Presentation] Rab44はコラーゲン抗体誘発性関節炎において炎症反応を制御する2023
- Author(s)
  山口　優，門脇　知子，坂井　詠子，野黒美　麻由子，親川　駿, 日浅　匠，馬渡　遥香，筑波　隆幸
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4のRUNドメイン欠失変異体は糸状仮足形成を促進し破骨細胞の骨吸収を抑制する2023
- Author(s)
  坂井詠子, 小柳悠, Farhana Fatima, 山口優，筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K09152
[Presentation] Rab44は筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により筋再生を負に制御する2023
- Author(s)
  親川駿、山口優，門脇知子，坂井詠子, 野黒美麻由子, 谷本あゆ子, 筑波　隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4のRUNドメイン欠失変異体は糸状仮足形成を促進し破骨細胞の骨吸収を抑制する2023
- Author(s)
  坂井詠子, 小栁悠, Farhana Fatima, 山口優，筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4のRUNドメイン欠失変異体は糸状仮足形成を促進し破骨細胞の骨吸収を抑制する2023
- Author(s)
  坂井詠子, 小栁悠, Farhana Fatima, 山口優，筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K09507
[Presentation] Dennd2cは破骨細胞分化を負に制御する2023
- Author(s)
  小栁　悠、坂井　詠子、山口　優、Farhana Fatima、平　曜輔、村田比呂司、筑波　隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する2023
- Author(s)
  谷本あゆ子、山口優，門脇知子，坂井詠子, 親川駿, 筑波隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09507
[Presentation] Rab44は筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により筋再生を負に制御する2023
- Author(s)
  親川駿、山口優，門脇知子，坂井詠子, 野黒美麻由子, 谷本あゆ子, 筑波　隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09507
[Presentation] 高分子量Rabタンパク質が制御する筋芽細胞から筋管への分化機構2022
- Author(s)
  谷本　あゆ子，山口　優，門脇　知子，親川駿, 坂井　詠子，小野悠介，吉田　教明，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4はRUNドメインを介して破骨細胞による骨吸収を制御する2022
- Author(s)
  坂井詠子, Farhana Fatima, 小栁悠, 山口優，筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口　優，門脇　知子，相原　希美，大山　要，岡元　邦彰，坂井　詠子，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口　優，門脇　知子，相原　希美，大山　要，岡元　邦彰，坂井　詠子，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 高分子量Rabタンパク質が制御する筋芽細胞から筋管への分化機構2022
- Author(s)
  谷本　あゆ子，山口　優，門脇　知子，親川駿, 坂井　詠子，小野悠介，吉田　教明，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] Rab44タンパク質による炎症応答制御機構2022
- Author(s)
  門脇知子、山口　優、佐藤啓子、筑波隆幸
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4はRUNドメインを介して破骨細胞による骨吸収を制御する2022
- Author(s)
  坂井詠子, Farhana Fatima, 小栁悠, 山口優，筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] Rab44タンパク質による炎症応答制御機構2022
- Author(s)
  門脇知子、山口　優、佐藤啓子、筑波隆幸
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 高分子量Rabタンパク質による筋衛星細胞と筋形成過程に及ぼす影響2022
- Author(s)
  親川駿、山口優，門脇知子，谷本あゆ子, 坂井詠子，村田比呂司、筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 高分子量Rabタンパク質による筋衛星細胞と筋形成過程に及ぼす影響2022
- Author(s)
  親川駿、山口優，門脇知子，谷本あゆ子, 坂井詠子，村田比呂司、筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口優　門脇知子　相原希美　大山要　岡元邦彰　坂井詠子　筑波隆幸
- Organizer
  第95回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K17004
[Presentation] 金属アレルギーでの高分子量Gタンパク質Rab44の役割2022
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、村田比呂司、筑波隆幸、門脇知子
- Organizer
  第4５回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 金属アレルギーでの高分子量Gタンパク質Rab44の役割2022
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、村田比呂司、筑波隆幸、門脇知子
- Organizer
  第4５回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] リソソームとアレルギー疾患制御2020
- Author(s)
  門脇知子、山口　優、筑波隆幸
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03860

1. Tsukuba Takayuki (30264055)

# of Collaborated Projects: 7 results

# of Collaborated Products: 36 results
2. Sakai Eiko (10176612)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
3. 門脇知子 (70336080)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 角忠輝 (80284701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Kido Mizuho (60253457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉本怜子 (70878181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 本田裕子 (60295053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西山めぐみ (00802844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佛坂斉祉 (90199513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 近藤好夫 (30581954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 永野健一 (60834348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 福間裕 (50253688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SATO Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 筑波知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 26 results

YAMAGUCHI Yu 山口 優

Research Projects

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小胞輸送系分子を基軸とする関節リウマチモデルマウスの病態解明Principal Investigator

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Imaging analysis of the dynamics of lysosomal membranes involved in the acidic environment of oral cancer cells

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変異型Rufy4を発現する破骨細胞の細胞外小胞を介した骨吸収調節機構の解明と応用

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Functional analysis of a novel membrane transport factor in metabolic bone diseases

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Elucidating the Pathophysiology of Osteoporosis Model Mice Using Novel Molecules Targeting Membrane Transport SystemsPrincipal Investigator

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Multimodal imaging analysis of oral cancer cells focused on lysosomes

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Elucidating the regulatory mechanism of osteoclast differentiation of Rab44 and its effects on bone tissuePrincipal Investigator

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Functional and pathological analyses of inflammatory bone destruction disease by a novel Rab protein

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Involvement of mechanosensors in periodontal disease

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Elucidation of the function of novel autophagy regulators related to oxidative stress and bone resorption

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Molecular mechanism of Rab44 regulation of osteoclast differentiation and function elucidation in vivo.Principal Investigator

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[Book] Studies in Natural Products Chemistry2022

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[Book] Studies in Natural Products Chemistry2021

Author(s)

Total Pages

Publisher

YAMAGUCHI Yu 山口優