Usui Toshiaki 臼井俊明

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臼井俊明ウスイトシアキ

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Researcher Number	50825099
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 講師
Affiliation (based on the past Project Information) *help	2025: 筑波大学, 医学医療系, 講師 2021 – 2023: 筑波大学, 医学医療系, 講師 2018 – 2019: 筑波大学, 医学医療系, 講師
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / 0904:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 転写因子 / 糸球体上皮細胞 / PI3K-Akt / MCTO / 疾患モデルマウス / 巣状糸球体硬化症 / MAFB / atRA / 誘導剤 / 巣状分節性糸球体硬化症 / 慢性腎臓病 / MafB

MAFB誘導薬を糸球体上皮細胞障害をきたす慢性腎臓病の治療へ応用するための基盤研究Principal Investigator
- Principal Investigator
  
  臼井俊明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Tsukuba
糸球体上皮細胞特異的転写因子MAFB変異による巣状糸球体硬化症発症メカニズム解析Principal Investigator
- Principal Investigator
  
  臼井俊明
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Tsukuba
Application for treatments of chronic kidney disease used by podocyte specific transcription factor MafBPrincipal Investigator
- Principal Investigator
  
  Usui Toshiaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba

All 2024 2023 2022 2021 2020 2018

All Journal Article Presentation

[Journal Article] Podocyte-specific Transcription Factors: Could MafB Become a Therapeutic Target for Kidney Disease?2023
- Author(s)
  Morito Naoki、Usui Toshiaki、Ishibashi Shun、Yamagata Kunihiro
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 1 Pages: 11-19
- DOI
  10.2169/internalmedicine.9336-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08220, KAKENHI-PROJECT-21K16157
[Journal Article] Mice Lacking Core 1-derived O-glycan in Podocytes Develop Transient Proteinuria, Resulting in Focal Segmental Glomerulosclerosis2020
- Author(s)
  Sayaka Fuseya, Riku Suzuki, Risa Okada, Kozue Hagiwara, Takashi Sato, Hisashi Narimatsu , Hideki Yokoi, Masato Kasahara, Toshiaki Usui , Naoki Morito, Kunihiro Yamagata, Takashi Kudo , Satoru Takahashi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 523 Issue: 2 Pages: 1007-1013
- DOI
  10.1016/j.bbrc.2019.12.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08230, KAKENHI-PROJECT-19K07499, KAKENHI-PROJECT-19K21330
[Journal Article] Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.2020
- Author(s)
  Usui T, Morito N, Shawki HH, Sato Y, Tsukaguchi H, (20人略）, Takahashi S.
- Journal Title
  
  Kidney International
  
  Volume: in press Issue: 2 Pages: 391-403
- DOI
  10.1016/j.kint.2020.02.038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09719, KAKENHI-PROJECT-19K17752, KAKENHI-PROJECT-19K21330, KAKENHI-PROJECT-20K08624, KAKENHI-PROJECT-20K08633, KAKENHI-PROJECT-18K08230
[Presentation] 多中心性手根足根骨溶解症(MCTO)関連腎症に対するMAFB-IGF1-PI3K/AKTシグナル抑制は潜在的な治療選択肢である2024
- Author(s)
  石橋駿、臼井俊明、森戸直記、濱田理人、久野朗広、水野聖哉、田中亮二郎、高橋智、山縣邦弘
- Organizer
  第67回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K16157
[Presentation] EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY2023
- Author(s)
  Toshiaki Usui, Naoki Morito, Shun Ishibashi, Natalia Gogoleva, Maho Kanai, Yuri Inoue, Sayaka Fuseya, Akihiro Kuno, Seiya Mizuno, Michito Hamada, Satoru Takahashi, Kunihiro Yamagata
- Organizer
  The 60th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16157
[Presentation] EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY2023
- Author(s)
  Toshiaki Usui; Naoki Morito; Shun Ishibashi; Maho Kanai; Natalia Gogoleva; Yuri Inoue; Sayaka Fuseya; Akihiro Kuno; Michito Hamada; Seiya Mizuno; Satoru Takahashi; Kunihiro Yamagata
- Organizer
  ERA-EDTA 60th CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16157
[Presentation] MAFB変異疾患 (MCTO)モデルマウスのポドサイト障害に対するイマチニブの治療効果2022
- Author(s)
  臼井俊明; 森戸直記; 石橋駿; 西野哲平; 金井真帆; Natalia Gogoleva; 井上由理; 布施谷清香; 久野朗広;濱田理人;水野聖哉; 高橋智; 山縣邦弘
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K16157
[Presentation] MAFB変異部位の違いによる巣状分節性糸球体硬化症の発症メカニズムの相違2021
- Author(s)
  臼井俊明; 森戸直記; 金井真帆; 綱川祐貴; 濱田理人; 全孝静; 水野聖哉; 高橋智; 山縣邦弘
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K16157
[Presentation] 巣状分節性糸球体硬化症の治療ターゲットとしてのMafBの可能性2018
- Author(s)
  臼井　俊明
- Organizer
  第61回日本腎臓学会学術集会総会
- Data Source
  KAKENHI-PROJECT-19K21330

1. MORITO Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 塚口裕康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Usui Toshiaki 臼井 俊明

臼井 俊明 ウスイ トシアキ

Research Projects

Research Products

Co-Researchers

MAFB誘導薬を糸球体上皮細胞障害をきたす慢性腎臓病の治療へ応用するための基盤研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糸球体上皮細胞特異的転写因子MAFB変異による巣状糸球体硬化症発症メカニズム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application for treatments of chronic kidney disease used by podocyte specific transcription factor MafBPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Podocyte-specific Transcription Factors: Could MafB Become a Therapeutic Target for Kidney Disease?2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Mice Lacking Core 1-derived O-glycan in Podocytes Develop Transient Proteinuria, Resulting in Focal Segmental Glomerulosclerosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 多中心性手根足根骨溶解症(MCTO)関連腎症に対するMAFB-IGF1-PI3K/AKTシグナル抑制は潜在的な治療選択肢である2024

Author(s)

Organizer

Data Source

[Presentation] EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY2023

Author(s)

Organizer

Data Source

[Presentation] EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY2023

Author(s)

Organizer

Data Source

[Presentation] MAFB変異疾患 (MCTO)モデルマウスのポドサイト障害に対するイマチニブの治療効果2022

Author(s)

Organizer

Data Source

[Presentation] MAFB変異部位の違いによる巣状分節性糸球体硬化症の発症メカニズムの相違2021

Author(s)

Organizer

Data Source

[Presentation] 巣状分節性糸球体硬化症の治療ターゲットとしてのMafBの可能性2018

Author(s)

Organizer

Data Source

Usui Toshiaki 臼井俊明

臼井俊明ウスイトシアキ