Yamamoto Shota 山本将大

… Alternative Names

Shota Yamamoto 山本将大

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Researcher Number	50825693
Other IDs
Affiliation (Current)	2025: 九州大学, 生体防御医学研究所, 助教
Affiliation (based on the past Project Information) *help	2023: 九州大学, 生体防御医学研究所, 助教 2019 – 2022: 国立研究開発法人国立国際医療研究センター, その他部局等, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 疼痛 / 神経障害性疼痛 / リゾリン脂質アシル転移酵素 / 生体膜リン脂質 / LPCAT3 / リン脂質 / アラキドン酸 / リピドミクス / リン脂質生合成酵素 / ドラッグリポジショニング / 感覚情報伝達 / 後根神経節 / 脂質メディエーター … More Except Principal Investigator … More がん化学療法 / 脂質メディエーター / 抗がん薬 / ドラッグリポジショニング / グリセロリン脂質 / 生体膜リン脂質 / 末梢神経障害 Less

アラキドン酸含有リン脂質が担う難治性疼痛の新しい病態メカニズムPrincipal Investigator
- Principal Investigator
  
  山本将大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyushu University
生体膜リン脂質に着目した抗がん薬誘発末梢神経障害予防/治療薬の開発
- Principal Investigator
  
  江頭伸昭
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Wakayama Medical University
  Kyushu University
Drug repositioning research targeting new pain control molecules, lysophospholipid acyltransferasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shota
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Center for Global Health and Medicine
Study for the mechanism underlying neuropathic pain by manipulating the membrane phospholipidPrincipal Investigator
- Principal Investigator
  
  Shota Yamamoto
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Center for Global Health and Medicine

All 2024 2023 2022 2021 2020 2019 Other

All Journal Article Presentation Book Other

[Book] 神経障害性疼痛と血小板活性化因子（PAF）2023
- Author(s)
  進藤英雄，山本将大
- Publisher
  実験医学（羊土社）
- Data Source
  KAKENHI-PROJECT-23K06820
[Journal Article] Macrophage/microglia-producing transient increase of platelet-activating factor is involved in neuropathic pain2024
- Author(s)
  Yamamoto Shota、Hashidate-Yoshida Tomomi、Yoshinari Yuki、Shimizu Takao、Shindou Hideo
- Journal Title
  
  iScience
  
  Volume: － Issue: 4 Pages: 109466-109466
- DOI
  10.1016/j.isci.2024.109466
- Data Source
  KAKENHI-PROJECT-23K06820, KAKENHI-PROJECT-22KJ3239
[Journal Article] Lipid in microglial biology ? from material to mediator2023
- Author(s)
  Yamamoto Shota、Masuda Takahiro
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1 Pages: 38-38
- DOI
  10.1186/s41232-023-00289-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06820, KAKENHI-PROJECT-22KJ3239, KAKENHI-PLANNED-22H05062, KAKENHI-PROJECT-23K21383
[Journal Article] Profiling of fatty acid metabolism in the dorsal root ganglion after peripheral nerve injury2022
- Author(s)
  Yamamoto Shota、Hashidate-Yoshida Tomomi、Shimizu Takao、Shindou Hideo
- Journal Title
  
  Frontiers in Pain Research
  
  Volume: 3
- DOI
  10.3389/fpain.2022.948689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ3239, KAKENHI-PROJECT-21K15309
[Journal Article] Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity2022
- Author(s)
  Zhang W, Matsukane R, Egashira N, Tsuchiya Y, Fu R, Yamamoto S, Hirota T, Ieiri I
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 449 Pages: 116112-116112
- DOI
  10.1016/j.taap.2022.116112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06670, KAKENHI-PROJECT-22KJ3239, KAKENHI-PROJECT-21K15309
[Journal Article] Pathological Mechanisms of Bortezomib-Induced Peripheral Neuropathy2021
- Author(s)
  Yamamoto Shota、Egashira Nobuaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 2 Pages: 888-888
- DOI
  10.3390/ijms22020888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-19K16938
[Journal Article] Drug Repositioning for the Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy: A Mechanism- and Screening-Based Strategy2021
- Author(s)
  Yamamoto Shota、Egashira Nobuaki
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 607780-607780
- DOI
  10.3389/fphar.2020.607780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-19K16938
[Journal Article] Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats2021
- Author(s)
  Egashira N, Goto Y, Takahashi R, Iba H, Yamamoto S, Watanabe T, Kubota K, Kawashiri T, Taniguchi C, Katsurabayashi S, Iwasaki K
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 147 Issue: 1 Pages: 114-117
- DOI
  10.1016/j.jphs.2021.06.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-21K06670, KAKENHI-PROJECT-21K15309, KAKENHI-PROJECT-22KJ3239
[Journal Article] Lipid signaling in chemotherapy-induced peripheral neuropathy2021
- Author(s)
  Yamamoto S, Egashira N
- Journal Title
  
  Current Opinion in Toxicology
  
  Volume: 28 Pages: 1-6
- DOI
  10.1016/j.cotox.2021.08.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-21K06670, KAKENHI-PROJECT-21K15309, KAKENHI-PROJECT-22KJ3239
[Journal Article] Lysophosphatidylethanolamine acyltransferase 2 (LPEAT2) incorporates DHA into phospholipids and has possible functions for fatty acid-induced cell death2020
- Author(s)
  Eto Miki、Shindou Hideo、Yamamoto Shota、Tamura-Nakano Miwa、Shimizu Takao
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 526 Issue: 1 Pages: 246-252
- DOI
  10.1016/j.bbrc.2020.03.074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16938
[Journal Article] Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development2020
- Author(s)
  Valentine William J.、Hashidate-Yoshida Tomomi、Yamamoto Shota、Shindou Hideo
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 1274 Pages: 5-27
- DOI
  10.1007/978-3-030-50621-6_2
- ISBN
  9783030506209, 9783030506216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16938
[Presentation] Increased arachidonic acid-containing phospholipids in the dorsal root ganglion contribute to the pathogenesis of neuropathic pain2023
- Author(s)
  Shota Yamamoto, Tomomi Hashidate-Yoshida, Takao Shimizu, Hideo Shindou
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06820
[Presentation] Role of arachidonic acid-containing phospholipids in neuropathic pain.2023
- Author(s)
  山本将大，清水孝雄，進藤英雄
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15309
[Presentation] 末梢神経損傷時に増加するPAFの産生細胞特定と疼痛への関与2022
- Author(s)
  山本将大，吉田(橋立)智美，清水孝雄，進藤英雄
- Organizer
  第64回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-21K15309
[Presentation] Macrophage/microglia-produced platelet-activating factor contribute to the development of neuropathic pain.2022
- Author(s)
  Yamamoto S, Hashidate-Yoshida T, Shimizu T, Shindou H
- Organizer
  Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15309
[Presentation] “Quality of Lipid” in the dorsal root ganglion2021
- Author(s)
  山本将大，清水孝雄，進藤英雄
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16938
[Presentation] Platelet-activating factor (PAF) is increased in neuropathic pain mice: different regulation of PAF levels between the spinal cord and the dorsal root ganglia.2020
- Author(s)
  山本将大，吉田（橋立）智美，進藤英雄，清水孝雄
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16938
[Presentation] 神経障害性疼痛マウスモデルの後根神経節におけるリン脂質組成および脂質メディエーターの網羅的解析2019
- Author(s)
  山本将大，吉田（橋立）智美，進藤英雄，清水孝雄
- Organizer
  第13回日本緩和医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K16938
[Presentation] 抗がん薬オキサリプラチン誘発末梢神経障害に対する新規予防薬の探索2019
- Author(s)
  山本将大
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K16938
[Presentation] 神経障害性疼痛マウスモデルの後根神経節および脊髄における包括的脂質解析2019
- Author(s)
  山本将大，吉田（橋立）智美，進藤英雄，清水孝雄
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16938
[]

1. 江頭伸昭 (80352269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 川尻雄大 (30621685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 吉田智美 (30610216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Yamamoto Shota 山本 将大

Shota Yamamoto 山本 将大

Research Projects

Research Products

Co-Researchers

アラキドン酸含有リン脂質が担う難治性疼痛の新しい病態メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体膜リン脂質に着目した抗がん薬誘発末梢神経障害予防/治療薬の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug repositioning research targeting new pain control molecules, lysophospholipid acyltransferasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for the mechanism underlying neuropathic pain by manipulating the membrane phospholipidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 神経障害性疼痛と血小板活性化因子（PAF）2023

Author(s)

Publisher

Data Source

[Journal Article] Macrophage/microglia-producing transient increase of platelet-activating factor is involved in neuropathic pain2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid in microglial biology ? from material to mediator2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Profiling of fatty acid metabolism in the dorsal root ganglion after peripheral nerve injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological Mechanisms of Bortezomib-Induced Peripheral Neuropathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug Repositioning for the Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy: A Mechanism- and Screening-Based Strategy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid signaling in chemotherapy-induced peripheral neuropathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lysophosphatidylethanolamine acyltransferase 2 (LPEAT2) incorporates DHA into phospholipids and has possible functions for fatty acid-induced cell death2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development2020

Author(s)

Yamamoto Shota 山本将大

Shota Yamamoto 山本将大