Liu Norika 劉孟佳

… Alternative Names

Liu Norika (Mengchia) 劉孟佳

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Researcher Number	50826922
Other IDs
Affiliation (Current)	2025: 熊本大学, 国際先端医学研究機構, 特任講師
Affiliation (based on the past Project Information) *help	2024: 熊本大学, 国際先端医学研究機構, 特任講師 2024: 熊本大学, 国際先端医学研究機構, 特定事業研究員 2023: 東京慈恵会医科大学, 医学部, 講師 2022: 東京慈恵会医科大学, 医学部, 特任講師 2018 – 2022: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員 2021: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 44020:Developmental biology-related / 0802:Biomedical structure and function and related fields Except Principal Investigator Basic Section 48010:Anatomy-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 単球 / マクロファージ / 老化 / 血管 / 心臓 / 心血管発生 / 大血管リモデリング / 組織定住マクロファージ / 内皮造血 / シングルセルRNAシーケンス … More / レチノイン酸シグナル / Notchシグナル / Nkx2-5 / 組織マクロファージ / 組織リモデリング / 内皮細胞性造血 / エンハンサー / ALK1 / TMEM100 / 血管新生 / ALK1シグナル / 新生仔網膜 / 血管リモデリング / 転写制御機構 / Tmem100 / 血管内皮細胞 … More Except Principal Investigator 発生 / ゲノムバーコード / 心臓弁膜症 / マクロファージ / 心内膜造血 / Notch/Rbpjシグナル伝達経路 / 心室筋 / 細胞系譜 / 転写 / 心筋 / エンハンサー / 転写制御 / 細胞分化 / 胸部大血管 / 心臓 / マウス / 脈管 / 遺伝性出血性末梢血管拡張症 / ゼブラフィッシュ / 血管 / 難治性血管病 / 形態形成 / 心血管発生 / 心筋細胞 / 内皮細胞 / シグナル伝達 / 遺伝子組換えマウス / 細胞シグナル伝達 / 遺伝性血管病 / 先天性心血管疾患 Less

心臓の組織老化を招くマクロファージの発見と役割の解明Principal Investigator
- Principal Investigator
  
  劉孟佳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kumamoto University
心内膜造血の証明
- Principal Investigator
  
  中野敦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Jikei University School of Medicine
大血管リモデリングにおける組織定住マクロファージの役割Principal Investigator
- Principal Investigator
  
  劉孟佳
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Jikei University School of Medicine
Role of vascular interaction in embryonic development
- Principal Investigator
  
  Urasaki Akihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  National Cardiovascular Center Research Institute
Molecular mechanisms of cell differentiation during development of great vessels and ventricles
- Principal Investigator
  
  Watanabe Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  National Cardiovascular Center Research Institute
Significance of cellular signaling pathways in cardiovascular development and disease
- Principal Investigator
  
  NAKAGWA Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Regulatory mechanisms of endothelial-specific expression and cellular functions of Tmem100 during vascular formationPrincipal Investigator
- Principal Investigator
  
  Liu Norika (Mengchia)
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0802:Biomedical structure and function and related fields
- Research Institution
  National Cardiovascular Center Research Institute

All 2023 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-52023
- Author(s)
  Liu Norika、Kawahira Naofumi、Nakashima Yasuhiro、Nakano Haruko、Iwase Akiyasu、Uchijima Yasunobu、Wang Mei、Wu Sean M.、Minamisawa Susumu、Kurihara Hiroki、Nakano Atsushi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 5398-5398
- DOI
  10.1038/s41467-023-41039-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113, KAKENHI-PROJECT-19K24689, KAKENHI-PROJECT-22K20917, KAKENHI-PROJECT-21H02884
[Journal Article] Response to Matters Arising: Intercellular genetic tracing of cardiac endothelium in the developing heart2023
- Author(s)
  Nakano Atsushi、Liu Norika
- Journal Title
  
  Developmental Cell
  
  Volume: 58 Issue: 16 Pages: 1513-1514
- DOI
  10.1016/j.devcel.2023.05.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113, KAKENHI-PROJECT-19K24689
[Journal Article] Changes in macrophage immunometabolism as a marker of skeletal muscle dysfunction across the lifespan2023
- Author(s)
  Liu Norika、Butcher Joshua T.、Nakano Atsushi、del Campo Andrea
- Journal Title
  
  Aging
  
  Volume: 15 Issue: 10 Pages: 4035-4050
- DOI
  10.18632/aging.204750
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113, KAKENHI-PROJECT-19K24689
[Journal Article] Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation2021
- Author(s)
  Yumi Kinugasa-Katayama, Yusuke Watanabe, Takashi Hisamitsu, Yuichiro Arima, Norika M Liu, Ayaka Tomimatsu, Yukihiro Harada, Yuji Arai, Akihiro Urasaki, Teruhisa Kawamura, Yoshihiko Saito, Osamu Nakagawa
- Journal Title
  
  genesis
  
  Volume: 59 Issue: 4
- DOI
  10.1002/dvg.23416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07280, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398, KAKENHI-PROJECT-21H02890
[Presentation] Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-52023
- Author(s)
  Norika Liu, Atsushi Nakano
- Organizer
  CVMW2023 心血管代謝週間
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] 胎生期の心臓形態形成時に起こる内皮造血の分子制御機構とその意義2023
- Author(s)
  劉　孟佳
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] 心臓の形態形成に重要な組織マクロファージの分化機構の解明2023
- Author(s)
  Norika Liu , Naofumi Kawahira , Yasuhiro Nakashima , Haruko Nakano , Akiyasu Iwase , Yasunobu Uchijima , Sean Wu , Susumu Minamisawa , Hiroki Kurihara , Atsushi Nakano
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] 胎生期内皮細胞性造血による心臓形態形成への寄与2022
- Author(s)
  劉孟佳
- Organizer
  第27回心血管内分泌代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Novel molecular mechanisms of endocardial hematopoiesis and their significance in cardiac physiology.2022
- Author(s)
  Norika Liu
- Organizer
  Chilean Society of Physiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Novel regulatory mechanism of hemogenic endocardium during cardiovascular development.2022
- Author(s)
  Norika Liu
- Organizer
  Weinstein Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Novel regulatory mechanism of hemogenic endocardium during cardiovascular development.2022
- Author(s)
  Norika Liu
- Organizer
  International Society for Experimental Hematology, 51st Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Endocardial hematopoiesis facilitates the heart morphogenesis.2022
- Author(s)
  劉孟佳
- Organizer
  CVMW2022 心血管代謝週間
- Invited
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] 胎生期の心臓形態形成時に起こる内皮造血の分子制御機構の解明2021
- Author(s)
  劉孟佳
- Organizer
  2021年度生理研心血管研究会
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Novel regulatory mechanism of hemogenic endocardium during cardiovascular development2021
- Author(s)
  劉孟佳
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] Novel regulatory mechanism of hemogenic endocardium during cardiovascular development2021
- Author(s)
  Norika Liu
- Organizer
  The 5th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-21K15113
[Presentation] 胚発生における心血管シグナル伝達系と環境因子の相互関係2019
- Author(s)
  浦﨑明宏、田中亨、原田恭弘、劉孟佳、川村晃久、渡邉裕介、中川修
- Organizer
  第23回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 胎生期血管内皮遺伝子Tmem100の転写制御機構と血管形成における意義2019
- Author(s)
  劉孟佳、片山由美、渡邉裕介、荒井勇二、磯本祥恵、中野厚史、上村-鎌田麻実、福嶋葉子、久保田義顕、植村明嘉、金井克晃、中川修
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 胚発生における心血管シグナル伝達系と環境因子の相互関係2019
- Author(s)
  浦﨑明宏、田中亨、原田恭弘、劉孟佳、川村晃久、渡邉裕介、中川修
- Organizer
  第23回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-19K07280
[Presentation] 胚発生における心血管シグナル伝達系と環境因子の相互関係2019
- Author(s)
  浦﨑明宏、田中亨、原田恭弘、劉孟佳、川村晃久、渡邉裕介、中川修
- Organizer
  第23回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of Hey transcription factors in endothelial cell differentiation and embryonic vascular development2019
- Author(s)
  Toru TANAKA, Norika LIU, Shoko TAMURA, Daiki SEYA, Yusuke WATANABE, Osamu NAKAGAWA
- Organizer
  NAVBO Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] BMP-ALK1シグナル伝達系の新規下流遺伝子群の発現制御と機能解析2019
- Author(s)
  浦﨑明宏、渡邉裕介、原田恭弘、田中亨、劉孟佳、中川修
- Organizer
  第6回日本HHT研究会
- Data Source
  KAKENHI-PROJECT-19K07280
[Presentation] 胎生期血管内皮遺伝子Tmem100の転写制御機構と血管形成における意義2019
- Author(s)
  劉　孟佳
- Organizer
  第27回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-19K21249
[Presentation] Significance of Hey transcription factors in endothelial cell differentiation and embryonic vascular development2019
- Author(s)
  Toru TANAKA, Norika LIU, Shoko TAMURA, Daiki SEYA, Yusuke WATANABE, Osamu NAKAGAWA
- Organizer
  NAVBO Vascular Biology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] BMP-ALK1シグナル伝達系の新規下流遺伝子群の発現制御と機能解析2019
- Author(s)
  浦﨑明宏、渡邉裕介、原田恭弘、田中亨、劉孟佳、中川修
- Organizer
  第6回日本HHT研究会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 胎生期血管内皮遺伝子Tmem100の転写制御機構と血管形成における意義2019
- Author(s)
  劉孟佳、片山由美、渡邉裕介、荒井勇二、磯本祥恵、中野厚史、上村-鎌田麻実、福嶋葉子、久保田義顕、植村明嘉、金井克晃、中川修
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Transcriptional regulation and physiological significance of ALK1 target genes in endothelial cells2018
- Author(s)
  Norika LIU, Yukihiro HARADA, Toru TANAKA, Teruhisa KAWAMURA, Yoshihiko SAITO, Osamu NAKAGAWA
- Organizer
  日本循環器学会　第2回Basic Cardiovascular Research Conference
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Transcriptional regulation and physiological significance of BMP-ALK1 signal target genes in embryonic vascular endothelial cells2018
- Author(s)
  Osamu NAKAGAWA, Yusuke WATANABE, Yumi KINUGASA-KATAYAMA, Tomoe NAKAMURA-NISHITANI, Yukihiro HARADA, Norika Liu, Toru TANAKA, Daiki SEYA, Dai IHARA, Teruhisa KAWAMURA
- Organizer
  12th International BMP Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Transcriptional regulation and physiological significance of ALK1 target genes in endothelial cells2018
- Author(s)
  Norika LIU, Yukihiro HARADA, Toru TANAKA, Teruhisa KAWAMURA, Yoshihiko SAITO, Osamu NAKAGAWA
- Organizer
  日本血管生物医学会　第16回Korea-Japan Joint Symposium
- Data Source
  KAKENHI-PROJECT-18H02787

1. NAKAGWA Osamu (40283593)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. Watanabe Yusuke (20562333)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. Urasaki Akihiro (40550083)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. LAMRI LYNDA (90883984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 瀬谷大貴 (30806021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 田中亨 (50806065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. 垣花優希 (40910534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 橋本大輝 (40911342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 原田恭弘 (70911402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
10. 田村昌子 (30849261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 西谷友重 (50393244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 小柴和子 (30467005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 能丸寛子 (30885538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中野敦 (10504368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Packwood Daniel (40640884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Liu Norika 劉 孟佳

Liu Norika (Mengchia) 劉 孟佳

Research Projects

Research Products

Co-Researchers

心臓の組織老化を招くマクロファージの発見と役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心内膜造血の証明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大血管リモデリングにおける組織定住マクロファージの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of vascular interaction in embryonic development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of cell differentiation during development of great vessels and ventricles

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Significance of cellular signaling pathways in cardiovascular development and disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanisms of endothelial-specific expression and cellular functions of Tmem100 during vascular formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-52023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response to Matters Arising: Intercellular genetic tracing of cardiac endothelium in the developing heart2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in macrophage immunometabolism as a marker of skeletal muscle dysfunction across the lifespan2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-52023

Author(s)

Organizer

Data Source

[Presentation] 胎生期の心臓形態形成時に起こる内皮造血の分子制御機構とその意義2023

Author(s)

Organizer

Data Source

[Presentation] 心臓の形態形成に重要な組織マクロファージの分化機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] 胎生期内皮細胞性造血による心臓形態形成への寄与2022

Liu Norika 劉孟佳

Liu Norika (Mengchia) 劉孟佳