otsu wataru 大津航

… Alternative Names

Otsu Wataru 大津航

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Researcher Number	50843091
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 特任准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 岐阜薬科大学, 薬学部, 特任講師 2019 – 2020: 岐阜薬科大学, 薬学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / 0605:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator 光障害 / 視細胞 / ライソゾーム / 網膜変性疾患 / 分泌小胞 / テトラスパニン / プログラニュリン / エンドソーム / バイオマーカー / 黄斑ディストロフィー / 錐体細胞

Role of extracellular vesicles in the progression of macular degenerationPrincipal Investigator
- Principal Investigator
  
  Otsu Wataru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Gifu Pharmaceutical University
Establishment of novel chemical screening assay for risk factors in cone photoreceptors of macular dystrophiesPrincipal Investigator
- Principal Investigator
  
  Otsu Wataru
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0605:Veterinary medical science, animal science, and related fields
- Research Institution
  Gifu Pharmaceutical University

All 2024 2023 2022 2021 2020 2019 Other

All Journal Article Presentation Other

[Journal Article] Investigation into the usefulness of cynomolgus monkeys with spontaneously elevated intraocular pressure as a model for glaucoma treatment research2024
- Author(s)
  Araki Tomoaki、Shimazawa Masamitsu、Nakamura Shinsuke、Otsu Wataru、Numata Yosuke、Sakata Megumi、Kabayama Koji、Tsusaki Hideshi、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 2 Pages: 52-60
- DOI
  10.1016/j.jphs.2023.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells2024
- Author(s)
  Yamazaki Kanta、Ishida Kodai、Otsu Wataru、Muramatsu Aomi、Nakamura Shinsuke、Yamada Wakana、Tsusaki Hideshi、Shimoda Hiroshi、Hara Hideaki、Shimazawa Masamitsu
- Journal Title
  
  BMC Complementary Medicine and Therapies
  
  Volume: 24 Issue: 1 Pages: 3-3
- DOI
  10.1186/s12906-023-04322-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Protective effect of crocetin against cytoskeletal injury induced by acrolein from cigarette smoke extract in C2C12 myoblasts2023
- Author(s)
  Otsu Wataru、Chinen Naoki、Sugisawa Emi、Kitano Haru、Nakamura Shinsuke、Umigai Naofumi、Tsusaki Hideshi、Shimazawa Masamitsu
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 106 Pages: 105611-105611
- DOI
  10.1016/j.jff.2023.105611
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Lipid Droplet Accumulation Promotes RPE Dysfunction2022
- Author(s)
  Yako Tomohiro、Otsu Wataru、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1790-1790
- DOI
  10.3390/ijms23031790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells2022
- Author(s)
  Otsu Wataru、Yako Tomohiro、Sugisawa Emi、Nakamura Shinsuke、Tsusaki Hideshi、Umigai Naofumi、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 150 Issue: 4 Pages: 279-288
- DOI
  10.1016/j.jphs.2022.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration2022
- Author(s)
  Chuang Jen-Zen、Yang Nan、Nakajima Nobuyuki、Otsu Wataru、Fu Cheng、Yang Howard Hua、Lee Maxwell Ping、Akbar Armaan Fazal、Badea Tudor Constantin、Guo Ziqi、Nuruzzaman Afnan、Hsu Kuo-Shun、Dunaief Joshua L.、Sung Ching-Hwa
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 374-374
- DOI
  10.1038/s41467-021-27935-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] The pathological association between the anterior eye segment and the retina in a murine model of neovascular glaucoma2022
- Author(s)
  Nishinaka Anri、Tanaka Miruto、Aoshima Kota、Kuriyama Aika、Sasaki Takahiro、Otsu Wataru、Yasuda Hiroto、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  The FASEB Journal
  
  Volume: 36 Issue: 6
- DOI
  10.1096/fj.202101917r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Mitochondria dynamics in the aged mice eye and the role in the RPE phagocytosis2021
- Author(s)
  Yako Tomohiro、Nakamura Maho、Otsu Wataru、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Experimental Eye Research
  
  Volume: 213 Pages: 108800-108800
- DOI
  10.1016/j.exer.2021.108800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Establishment of a pigmented murine model abundant with characteristics of retinal vein occlusion2021
- Author(s)
  Miyagi Sugao、Nishinaka Anri、Yamamoto Takumi、Otsu Wataru、Nakamura Shinsuke、Shimazawa Masamitsu、Kitaoka Takashi、Hara Hideaki
- Journal Title
  
  Experimental Eye Research
  
  Volume: 204 Pages: 108441-108441
- DOI
  10.1016/j.exer.2021.108441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19J15612, KAKENHI-PROJECT-19K23707
[Journal Article] Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation2021
- Author(s)
  Takahashi Kei、Nakamura Shinsuke、Otsu Wataru、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 18 Issue: 1 Pages: 164-164
- DOI
  10.1186/s12974-021-02203-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells2021
- Author(s)
  Otsu Wataru、Ishida Kodai、Chinen Naoki、Nakamura Shinsuke、Shimazawa Masamitsu、Tsusaki Hideshi、Hara Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18555-18555
- DOI
  10.1038/s41598-021-97956-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14999
[Journal Article] Brazilian green propolis promotes the cytoprotective expression of heme oxygenase-1 against oxidative stress injury in murine myoblast cells2020
- Author(s)
  Otsu Wataru、Chinen Naoki、Ohuchi Kazuki、Ando Shiori、Nakamura Shinsuke、Kono Hiroyuki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Functional Foods in Health and Disease
  
  Volume: 10 Issue: 12 Pages: 493-493
- DOI
  10.31989/ffhd.v10i12.756
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Tauroursodeoxycholic Acid Promotes Neuronal Survival and Proliferation of Tissue Resident Stem and Progenitor Cells in Retina of Adult Zebrafish2020
- Author(s)
  Yuichi Saito , Hiroyuki Okuyoshi , Shinsuke Nakamura , Wataru Otsu , Akihiro Yamaguchi , Peter F. Hitchcock , Mikiko Nagashima , Masamitsu Shimazawa , Hideaki Hara
- Journal Title
  
  BPB Reports
  
  Volume: 3 Pages: 92-96
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells2020
- Author(s)
  Otsu Wataru、Ishida Kodai、Nakamura Shinsuke、Shimazawa Masamitsu、Tsusaki Hideshi、Hara Hideaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 526 Issue: 2 Pages: 479-484
- DOI
  10.1016/j.bbrc.2020.03.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Anti-vascular Endothelial Growth Factor Antibody Limits the Vascular Leakage and Decreases Subretinal Fibrosis in a Cynomolgus Monkey Choroidal Neovascularization Model2020
- Author(s)
  Inagaki Satoshi、Shimazawa Masamitsu、Hamaguchi Koji、Otsu Wataru、Araki Tomoaki、Sasaki Yuji、Numata Yosuke、Tsusaki Hideshi、Hara Hideaki
- Journal Title
  
  Current Neurovascular Research
  
  Volume: 17 Issue: 4 Pages: 420-428
- DOI
  10.2174/1567202617666200523163636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Survival Motor Neuron Protein Modulates Lysosomal Function Through the Expression of Transcription Factor EB in Motoneurons2020
- Author(s)
  Shiori Ando , Wataru Otsu , Daiki Osanai , Satoshi Kamiya , Kodai Ishida , Shinsuke Nakamura , Masamitsu Shimazawa , Hideaki Hara
- Journal Title
  
  BPB Reports
  
  Volume: 3 Pages: 130-137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] A triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments in a p62-independent manner2020
- Author(s)
  Saito Yuichi、Yako Tomohiro、Otsu Wataru、Nakamura Shinsuke、Inoue Yuki、Muramatsu Aomi、Nakagami Yasuhiro、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 152 Pages: 235-247
- DOI
  10.1016/j.freeradbiomed.2020.03.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707, KAKENHI-PROJECT-17J10301, KAKENHI-PROJECT-19K09936
[Journal Article] Creation of retinal vein occlusion model in cynomolgusmonkeys and determination of its pathological features2020
- Author(s)
  Inagaki Satoshi、Shimazawa Masamitsu、Otsu Wataru、Araki Tomoaki、Numata Yosuke、Nakamura Shinsuke、Tsusaki Hideshi、Hara Hideaki
- Journal Title
  
  Current Neurovascular Research
  
  Volume: 17 Issue: 1 Pages: 123-133
- DOI
  10.2174/1567202617999200831151118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts2020
- Author(s)
  Kiatpakdee Benjaporn、Sato Kota、Otsuka Yayoi、Arashiki Nobuto、Chen Yuqi、Tsumita Takuya、Otsu Wataru、Yamamoto Akito、Kawata Reo、Yamazaki Jumpei、Sugimoto Yoshikazu、Takada Kensuke、Mohandas Narla、Inaba Mutsumi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 23 Pages: 8048-8063
- DOI
  10.1074/jbc.ra119.011679
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21356, KAKENHI-PROJECT-17H03928, KAKENHI-PROJECT-19K23707, KAKENHI-PROJECT-20H03138
[Journal Article] CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells2019
- Author(s)
  Hsu Kuo-Shun、Otsu Wataru、Li Yao、Wang Heuy-Ching、Chen Shuibing、Tsang Stephen H.、Chuang Jen-Zen、Sung Ching-Hwa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 12247-12247
- DOI
  10.1038/s41598-019-48438-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 22019
- Author(s)
  Otsu Wataru、Hsu Ya-Chu、Chuang Jen-Zen、Sung Ching-Hwa
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Pages: 2811-18
- DOI
  10.1523/jneurosci.2811-18.2019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707
[Journal Article] Mechanisms of cell proliferation through primary cilium2019
- Author(s)
  Saito Masaki、Otsu Wataru
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 154 Issue: 4 Pages: 197-202
- DOI
  10.1254/fpj.154.197
- NAID
  130007726220
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06125, KAKENHI-PROJECT-19K06739, KAKENHI-PROJECT-19K23707
[Presentation] Protective effect of active components of microalgae against photoreceptor damage induced by blue LED light and endoplasmic reticulum stress2023
- Author(s)
  Obayashi M., Yamazaki K, Otsu W., Nakamura S., Ishikawa Y., Sakata Y., Tsuboi M., Tsusaki H., Shimazawa M.
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] マウス視細胞の外節タンパク質輸送におけるプログラニュリンの役割2023
- Author(s)
  大津航, 角崎英志, 嶋澤雅光
- Organizer
  第２回Ocular Scientific Meeting ～眼科創薬研究会～
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] タバコ煙に含まれるカルボニル化合物によるアクチン骨格異常と筋管成熟阻害に対するクロセチンの保護作用2023
- Author(s)
  大津航、知念尚希、杉澤えみ、北野晴、中村信介、海貝尚史、角崎英志、嶋澤雅光
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] Progranulin regulates the ciliary transport of tetraspanins in murine photoreceptors2023
- Author(s)
  Otsu W., Tsusaki H., Shimazawa M.
- Organizer
  ARVO Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 網膜細胞におけるオプチニューリンE50K変異体よるリソソーム関連膜小器官異常の解析2023
- Author(s)
  大林茉由奈, 大津航, 角崎英志, 嶋澤雅光
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] マキベリー（Aristotelia chilensis）由来デルフィニジンの青色LED曝露によって誘発されるマウス光受容体由来細胞における細胞内器官の損傷に対する保護作用2023
- Author(s)
  山崎幹大、石田紘大、大津航、矢古宇智弘、中村信介、山田和佳奈、角崎英志、下田博司、原英彰、嶋澤雅光
- Organizer
  生体機能と創薬シンポジウム2023
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] マキベリー（Aristotelia chilensis）由来デルフィニジンの青色LED曝露によって誘発されるマウス光受容体由来細胞における細胞内器官の損傷に対する保護作用2023
- Author(s)
  山崎幹大、石田紘大、大津航、矢古宇智弘、中村信介、山田和佳奈、角崎英志、下田博司、原英彰、嶋澤雅光
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2023
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] マウス視細胞外節の形態とテトラスパニン輸送におけるプログラニュリンの役割2023
- Author(s)
  大津航, 大林茉由奈, 角崎英志, 嶋澤雅光
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] The expression of E50K optineurin affects the lysosome-related organelles in murine retinal cells2023
- Author(s)
  Otsu W., Obayashi M., Tsusaki H., Shimazawa M.
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 網膜オルガノイドを用いた糖尿病網膜症モデルの開発2022
- Author(s)
  中村信介、稲垣賢、青山八雲、青島弘汰、大津航、船戸道徳、嶋澤雅光、高橋一浩、原英彰
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 網脈絡膜変性病態におけるプログラニュリンの役割に関する研究2022
- Author(s)
  中村信介、髙橋慶、大津航、原英彰、嶋澤雅光
- Organizer
  第5回プログラニュリン研究会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 繊毛病の新規治療標的としての後期エンドソームの可能性2022
- Author(s)
  大津航
- Organizer
  第96回日本薬理学会年会, JPW2022
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 青色LED 光及び小胞体ストレスによる視細胞の障害に対する微細藻類由来活性成分の保護作用2022
- Author(s)
  大林茉由奈、大津航、山﨑幹大、青島弘汰、中村信介、石川英明、阪田泰子、坪井誠、角崎英志、嶋澤雅光
- Organizer
  第142回日本薬理学会・近畿部会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 網膜変性疾患における細胞内ストレス応答機構の役割2022
- Author(s)
  大津航
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] タバコ煙水抽出物および加熱式タバコ産物による筋芽細胞C2C12の細胞骨格形成障害に対するN-アセチルシステインの保護作用2022
- Author(s)
  大津航、知念尚希、石田紘大、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] マウス網膜由来細胞株661W細胞における加熱式タバコ産物とその成分による鉄依存性細胞死2022
- Author(s)
  大津航、杉澤えみ、知念尚希、中村信介、角崎英志、嶋澤雅光
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 角膜上皮細胞におけるUV-A 誘発ミトコンドリア障害に対するクロセチンの保護作用2022
- Author(s)
  杉澤えみ、大津航、矢古宇智弘、中村信介、角崎英志、海貝尚史、嶋澤雅光、原英彰
- Organizer
  第142回日本薬理学会・近畿部会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 青色LED光による視細胞の小胞体ストレス障害に対する微細藻類由来活性成分の保護作用2022
- Author(s)
  山﨑幹大、大津航、大林茉由奈、青島弘汰、中村信介、角崎英志、石川英明、阪田泰子、坪井誠、嶋澤雅光
- Organizer
  第15回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 加齢黄斑変性の新規モデル開発と網膜変性病態進行における後期エンドサイトーシス経路の役割2022
- Author(s)
  大津航
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] カニクイザル網膜静脈閉塞症モデルの確立と病態解明2021
- Author(s)
  稲垣賢、嶋澤雅光、大津航、荒木智陽、沼田洋輔、中村信介、角崎英志、原英彰
- Organizer
  第40回日本眼薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] マウス視細胞と網膜色素上皮における青色LED光ストレスの早期影響の解析2021
- Author(s)
  大津航、山﨑幹大、矢古宇智弘、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 青色LED光誘発視細胞障害に対するマキベリー抽出物とその成分の保護効果2021
- Author(s)
  山﨑幹大、石田紘大、大津航、矢古宇智弘、中村信介、山田和佳奈、角崎英志、下田博司、原英彰、嶋澤雅光
- Organizer
  第12回岐阜薬科大学機能性健康食品研究講演会
- Data Source
  KAKENHI-PROJECT-21K14999
[Presentation] 次世代タバコ抽出物による角膜上皮細胞の鉄依存的細胞死2021
- Author(s)
  大津航、石田紘大、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第40回日本眼薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] Triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments without p62 induction2020
- Author(s)
  Shinsuke Nakamura, Yuichi Saito, Tomohiro Yako, Wataru Otsu, Yuki Inoue, Aomi Muramatsu, Yasuhiro Nakagami, Masamitsu Shimazawa, Hideaki Hara
- Organizer
  ARVO 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 青色LED光障害に対するATF4経路を標的とした視細胞保護の検討2020
- Author(s)
  塩津佑果、大津航、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第138回日本薬理学会年会近畿部会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 運動ニューロンにおけるSMNタンパク質によるTFEBを介したライソゾーム関連因子の発現調節2020
- Author(s)
  大津航、安藤栞、長内大樹、神谷聡、石田紘大、中村信介、嶋澤雅光、原英彰
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] タバコ煙抽出物による角膜上皮細胞障害に対するエタノール抽出ブラジル産プロポリスによる保護作用2020
- Author(s)
  石田紘大、知念尚希、大津航、河野宏行、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第11回岐阜薬科大学機能性健康食品研究講演会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 紙タバコ及び加熱式タバコ煙抽出物による角膜上皮細胞死の分子メカニズム2020
- Author(s)
  石田紘大、知念尚希、大津航、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第138回日本薬理学会年会近畿部会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 視細胞と角膜上皮細胞における青色LED光誘発細胞障害の分子メカニズム2020
- Author(s)
  石田紘大、大津航、矢古宇智弘、中村信介、嶋澤雅光、角崎英志、原英
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 光誘発角膜上皮細胞障害に対する新規ラジカルスカベンジャーの保護作用2020
- Author(s)
  石田紘大、矢古宇智弘、大津航、中村信介、嶋澤雅光、角崎英志、原英彰
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 網膜静脈閉塞症モデルを用いた浮腫形成メカニズムに関する研究2019
- Author(s)
  中村信介、西中杏里、大津航、嶋澤雅光、原英彰
- Organizer
  第4回名大医薬系3部局交流シンポジウム
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] MICE WITH RPE-SPECIFIC CLIC4 DEFICIENCY EXHIBIT AMD-LIKE CHANGES IN THE RETINA-RPE-CHOROID COMPLEX.2019
- Author(s)
  Otsu W., Hsu KS., Dunaief JL., Li Y., Tsang SH., Chuang JZ., and Sung CH.
- Organizer
  ARVO Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707
[Presentation] 新規錐体細胞トランスフェクション法を用いたペリフェリン2の一次繊毛輸送のメカニズムの解析2019
- Author(s)
  大津航, Hsu YC., Chuang JZ., and Sung CH.
- Organizer
  第 42 回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K23707
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1. TAKADA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

otsu wataru 大津 航

Otsu Wataru 大津 航

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Role of extracellular vesicles in the progression of macular degenerationPrincipal Investigator

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Establishment of novel chemical screening assay for risk factors in cone photoreceptors of macular dystrophiesPrincipal Investigator

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[Journal Article] Investigation into the usefulness of cynomolgus monkeys with spontaneously elevated intraocular pressure as a model for glaucoma treatment research2024

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[Journal Article] Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells2024

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[Journal Article] Protective effect of crocetin against cytoskeletal injury induced by acrolein from cigarette smoke extract in C2C12 myoblasts2023

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[Journal Article] Lipid Droplet Accumulation Promotes RPE Dysfunction2022

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[Journal Article] Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells2022

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[Journal Article] Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration2022

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[Journal Article] The pathological association between the anterior eye segment and the retina in a murine model of neovascular glaucoma2022

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[Journal Article] Mitochondria dynamics in the aged mice eye and the role in the RPE phagocytosis2021

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[Journal Article] Establishment of a pigmented murine model abundant with characteristics of retinal vein occlusion2021

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[Journal Article] Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation2021

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[Journal Article] Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells2021

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[Journal Article] Brazilian green propolis promotes the cytoprotective expression of heme oxygenase-1 against oxidative stress injury in murine myoblast cells2020

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[Journal Article] Tauroursodeoxycholic Acid Promotes Neuronal Survival and Proliferation of Tissue Resident Stem and Progenitor Cells in Retina of Adult Zebrafish2020

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otsu wataru 大津航

Otsu Wataru 大津航