Takano Chika 高野智圭

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TAKANO Chika 高野智圭

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Researcher Number	50845310
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 日本大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator ヒト羊膜上皮細胞 / 先天性代謝異常症 / TNIK / 多能性と分化 / Wnt経路 / 胎盤 / 細胞治療 / 先天代謝異常症 / SB-431542 / TGF-β … More / TGF-β経路 / 上皮間葉転換 / 多能性幹細胞 / 羊膜上皮細胞 … More Except Principal Investigator 細胞移植 / 遺伝子改変ブタ / 幹細胞 / 羊膜上皮細胞 Less

Elucidation of switching mechanism in the Wnt pathway of human amniotic epithelial cellsPrincipal Investigator
- Principal Investigator
  
  高野智圭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nihon University
Evaluation of in vivo kinetics and fate of amnion epithelial stem cells after intraportal transplantation using transgenic pigs
- Principal Investigator
  
  三木敏生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Nihon University
Cell Therapy Development for Congenital Metabolic Diseases Using Human Amniotic Epithelial CellsPrincipal Investigator
- Principal Investigator
  
  TAKANO Chika
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nihon University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Patent

[Journal Article] Letter to the Editors: Concerning "Hyperleucinosis during infections in maple syrup urine disease post-liver transplantation" by Guilder et al2024
- Author(s)
  Chika Takano, Erika Ogawa, Natsuko Arai-Ichinoi, Mika Ishige
- Journal Title
  
  Molecular Genetics and Metabolism Reports
  
  Volume: 38 Pages: 101047-101047
- DOI
  10.1016/j.ymgmr.2023.101047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15421
[Journal Article] Insulin resistance in mitochondrial diabetes2023
- Author(s)
  Chika Takano, Erika Ogawa and Satoshi Hayakawa
- Journal Title
  
  Biomolecules
  
  Volume: 13(1) Issue: 1 Pages: 126-126
- DOI
  10.3390/biom13010126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17522
[Journal Article] Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells2022
- Author(s)
  Takano Chika、Horie Masafumi、Taiko Isamu、Trinh Quang Duy、Kanemaru Kazunori、Komine-Aizawa Shihoko、Hayakawa Satoshi、Miki Toshio
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 18 Issue: 8 Pages: 3083-3091
- DOI
  10.1007/s12015-022-10420-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19574, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-20K17522, KAKENHI-PROJECT-23K24398
[Journal Article] Selection of red fluorescent protein for genetic labeling of mitochondria and intercellular transfer of viable mitochondria2022
- Author(s)
  Taiko Isamu、Takano Chika、Nomoto Masayuki、Hayashida Shingo、Kanemaru Kazunori、Miki Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19841-19841
- DOI
  10.1038/s41598-022-24297-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06868, KAKENHI-PROJECT-22K19574, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-20K17522, KAKENHI-PROJECT-23K24398
[Patent] 羊膜由来幹細胞の維持培地、維持培地用サプリメント及び維持培養方法2020
- Inventor(s)
  三木敏生、高野智圭
- Industrial Property Rights Holder
  三木敏生、高野智圭
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] シングルセルRNA-seqを用いたヒト羊膜上皮細胞の系統学的多様性の解明2024
- Author(s)
  高野智圭、Dahlia Eldeeb 、堀江真史、太向勇、三木敏生
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] ヒト羊膜上皮細胞の分離・培養における臨床用試薬の検討2024
- Author(s)
  加賀三鈴、高野智圭、太向勇、三木敏生
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] ヒト羊膜上皮細胞移植により治療可能と考えられる先天性代謝異常症の探索2024
- Author(s)
  高野智圭、九鬼直人、加賀三鈴、三木敏生
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] ヒト羊膜上皮細胞を用いたⅡ型肺胞上皮細胞への分化誘導2024
- Author(s)
  野本正幸、太向勇、加賀三鈴、高野智圭、金丸和典、三木敏生
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] Direct differentiation of human amniotic epithelial cells to type II alveolar epithelial cells2023
- Author(s)
  Masayuki Nomoto, Isamu Taiko, Chika Takano, Kazunori Kanemaru, Toshio Miki
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] ヒト羊膜上皮細胞を用いたⅡ型肺胞上皮細胞への分化誘導2023
- Author(s)
  野本正幸, 太向勇, 高野智圭, 金丸和典, 三木敏生
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-23K24398
[Presentation] The first Japanese case of DNAJC12-deficiency: novel mutations and 18 years of follow-up for mHPA2023
- Author(s)
  Erika Ogawa, Chika Takano, Natsuko Ichinoi, Mika Ishige, Takashi Hamazaki, Hideo Sasai, Ichiro Morioka
- Organizer
  第64回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] シングルセル解析を用いたヒト羊膜上皮細胞の系統学的多様性の解明2023
- Author(s)
  高野智圭, 堀江真史, エルディーブダリア, 早川智, 三木敏生
- Organizer
  第31回日本胎盤学会学術集会/第41回日本絨毛性疾患研究会
- Data Source
  KAKENHI-PROJECT-23K24398
[Presentation] Single-cell transcriptomes reveal phylogenetic diversification of human amniotic epithelial cells2023
- Author(s)
  Chika Takano, Masafumi Horie, Dahlia Eldeeb, Isamu Taiko, Toshio Miki
- Organizer
  IPITA-IXA-CTRMS Joint Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] 急性代謝不全症状を呈したY435Cホモ変異最軽症型プロピオン酸血症の幼児例2023
- Author(s)
  高野智圭、小川えりか、市野井那津子、渡邉和宏、石毛信之、石毛美夏、森岡一朗
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] フェニルケトン尿症における食事療法が幼児期の腸内細菌叢に及ぼす影響2023
- Author(s)
  大海なつき、高野智圭、小川えりか、市野井那津子、石毛美夏、森岡一朗
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] ヒト羊膜上皮細胞における幹細胞特性維持機構の解明2023
- Author(s)
  高野智圭, 加賀三鈴, 太向勇, 樋口雄介, 三木敏生
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-23K24398
[Presentation] Causative gene expressions of metabolic diseases on human amniotic epithelial cells2023
- Author(s)
  Chika Takano, Naoto Kuki, Yutaka Furuta, Erika Ogawa, Mika Ishige, Toshio Miki
- Organizer
  第64回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] In vitro effects of 5-aminolevulinic acid on infantile mitochondrial disease caused by FBXL4 mutation2023
- Author(s)
  Chika Takano, Ryo Ikuta, Erika Ogawa, Kazunori Kanemaru, Natsuko Ichinoi, Satoshi Hayakawa, Ichiro Morioka, Mika Ishige
- Organizer
  44th Annual meeting of the Society for Inherited Metabolic Disorders
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] シングルセル解析を用いたヒト羊膜上皮細胞の系統学的多様性の解明2023
- Author(s)
  高野智圭, 堀江真史, エルディーブダリア, 早川智, 三木敏生
- Organizer
  第31回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15421
[Presentation] Mechanism of stemness maintenance in human amniotic epithelial cells2023
- Author(s)
  Chika Takano, Millei Kaga, Isamu Taiko, Yusuke Higuchi, Toshio Miki
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] 一過性メチルマロン酸血症を呈した 3-メチルクロトニルCoAカルボキシラーゼ欠損症の一例2022
- Author(s)
  高野智圭, 小川えりか, 市野井那津子, 石毛信之, 森岡一朗, 石毛美夏
- Organizer
  第49回日本マススクリーニング学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] Expression of Traf2- and Nck-interacting kinase in EMT-inhibited human amniotic epithelial cells2022
- Author(s)
  Chika Takano, Toshio Miki
- Organizer
  The Transplantation Society 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] FBLX4変異による乳児ミトコンドリア病における5-アミノレブリン酸効果のin vitro解析2022
- Author(s)
  高野智圭, 生田稜, 小川えりか, 金丸和典, 市野井那津子, 早川智, 森岡一朗, 石毛美夏
- Organizer
  第63回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] Expression of Traf2- and Nck-interacting kinase in EMT-inhibited human amniotic epithelial cells2022
- Author(s)
  Chika Takano、Toshio Miki
- Organizer
  29th International Congress of The Transplantation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24398
[Presentation] Comparison of laboratory- and clinical-grade reagents in isolation and cultivation of human amniotic epithelial cells2022
- Author(s)
  Chika Takano, Isamu Taiko, Remi Kuwabara, Ibrahim Fathi, Toshio Miki
- Organizer
  The Transplantation Society 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] 脂肪酸代謝異常症におけるアレルギー疾患の検討2022
- Author(s)
  高野智圭, 小川えりか, 市野井那津子, 石毛美夏, 岩間元子, 浦上達彦, 森岡一朗
- Organizer
  第125回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] Inhibition of epithelial mesenchymal transition maintains stemness in human amniotic epithelial cells2021
- Author(s)
  Chika Takano, Masafumi Horie, Toshio Miki
- Organizer
  Joint IXA-CTRMS Virtual Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17522
[Presentation] ヒト羊膜上皮細胞における上皮間葉転換と多能性に関する網羅的遺伝子解析2021
- Author(s)
  高野智圭、堀江真史、早川智、三木敏生
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17522

1. 三木敏生 (80845305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 三角浩司 (00442682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 淵本大一郎 (10343998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大西彰 (30414890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANEMARU Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 太向勇

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 堀江真史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takano Chika 高野 智圭

TAKANO Chika 高野 智圭

Research Projects

Research Products

Co-Researchers

Elucidation of switching mechanism in the Wnt pathway of human amniotic epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of in vivo kinetics and fate of amnion epithelial stem cells after intraportal transplantation using transgenic pigs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell Therapy Development for Congenital Metabolic Diseases Using Human Amniotic Epithelial CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Letter to the Editors: Concerning "Hyperleucinosis during infections in maple syrup urine disease post-liver transplantation" by Guilder et al2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin resistance in mitochondrial diabetes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selection of red fluorescent protein for genetic labeling of mitochondria and intercellular transfer of viable mitochondria2022

Author(s)

Journal Title

DOI

Data Source

[Patent] 羊膜由来幹細胞の維持培地、維持培地用サプリメント及び維持培養方法2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] シングルセルRNA-seqを用いたヒト羊膜上皮細胞の系統学的多様性の解明2024

Author(s)

Organizer

Data Source

[Presentation] ヒト羊膜上皮細胞の分離・培養における臨床用試薬の検討2024

Author(s)

Organizer

Data Source

[Presentation] ヒト羊膜上皮細胞移植により治療可能と考えられる先天性代謝異常症の探索2024

Author(s)

Organizer

Data Source

[Presentation] ヒト羊膜上皮細胞を用いたⅡ型肺胞上皮細胞への分化誘導2024

Author(s)

Organizer

Data Source

[Presentation] Direct differentiation of human amniotic epithelial cells to type II alveolar epithelial cells2023

Author(s)

Organizer

Data Source

[Presentation] ヒト羊膜上皮細胞を用いたⅡ型肺胞上皮細胞への分化誘導2023

Author(s)

Organizer

Data Source

[Presentation] The first Japanese case of DNAJC12-deficiency: novel mutations and 18 years of follow-up for mHPA2023

Author(s)

Organizer

Data Source

[Presentation] シングルセル解析を用いたヒト羊膜上皮細胞の系統学的多様性の解明2023

Author(s)

Organizer

Takano Chika 高野智圭

TAKANO Chika 高野智圭