NAGASAWA SHOTA 長澤翔太

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Nagasawa Shota 長澤翔太

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Researcher Number	50846425
Other IDs
Affiliation (Current)	2025: 東北大学, 薬学研究科, 助教
Affiliation (based on the past Project Information) *help	2019 – 2025: 東北大学, 薬学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / 0801:Pharmaceutical sciences and related fields Except Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 生物学的等価体 / かご型炭化水素 / C-H官能基化 / キュバン / 複素環化学 / hydrogen atom transfer / 創薬化学 / CーH官能基化 Except Principal Investigator ペプチド合成 / フェノールカップリング / 不斉合成 / 酸化触媒 / ハイブリッド触媒

キュバンの未踏医薬化学的ポテンシャルの開拓:beyond bioisosterePrincipal Investigator
- Principal Investigator
  
  長澤翔太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
高歪みかご型炭化水素の医薬化学的利用価値を拡張するための有機化学的方法論の開拓Principal Investigator
- Principal Investigator
  
  長澤翔太
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
有機ニトロキシルラジカルー遷移金属協奏触媒の機能創成を機軸とする精密有機分子構築
- Principal Investigator
  
  岩渕好治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
Transition-metal catalyzed C-H functionalization of cubane and its application to medicinal chemistryPrincipal Investigator
- Principal Investigator
  
  Nagasawa Shota
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
Radical-initiated C-H functionalization of cubane for medicinal chemistryPrincipal Investigator
- Principal Investigator
  
  Nagasawa Shota
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Tohoku University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] C-H Alkylation of Cubanes via Catalytic Generation of Cubyl Radicals2024
- Author(s)
  Masaki Hosaka, Shota Nagasawa, Yoshiharu Iwabuchi
- Journal Title
  
  Organic Letters
  
  Volume: 26 Issue: 3 Pages: 658-663
- DOI
  10.1021/acs.orglett.3c04019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14315, KAKENHI-PROJECT-23K24002
[Journal Article] Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction2024
- Author(s)
  Yamakoshi Hiroyuki、Fukuda Michihiro、Ikeda Hiro、Fujiki Shogo、Kohyama Aki、Nagasawa Shota、Shinozaki Hanae、Shibata Hiroyuki、Iwabuchi Yoshiharu
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 72 Issue: 1 Pages: 127-134
- DOI
  10.1248/cpb.c23-00775
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2024-01-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06495, KAKENHI-PROJECT-23K24002
[Journal Article] Biological Evaluation of Isosteric Applicability of 1,3-Substituted Cuneanes as m-Substituted Benzenes Enabled by Selective Isomerization of 1,4-Substituted Cubanes2024
- Author(s)
  Kan Fujiwara, Shota Nagasawa, Ryusei Maeyama, Ryosuke Segawa, Noriyasu Hirasawa, Takatsugu Hirokawa, Yoshiharu Iwabuchi
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 30 Issue: 11
- DOI
  10.1002/chem.202303548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14315, KAKENHI-PROJECT-21H00854, KAKENHI-PROJECT-23K24002
[Journal Article] 4-Chloro-2-azaadamantane N-Oxyl (4-Cl-AZADO): A Readily Preparable Organocatalyst for NOx Co-catalyzed Aerobic Alcohol Oxidation2023
- Author(s)
  Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
- Journal Title
  
  Asian Journal of Organic Chemistry
  
  Volume: 12 Issue: 4
- DOI
  10.1002/ajoc.202300031
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21H05210, KAKENHI-PROJECT-20K06961, KAKENHI-PROJECT-23K24002
[Journal Article] Asymmetric Total Synthesis of Cytotrienin A: Late‐Stage Installation of C11 Side Chain onto the Macrolactam Scaffold2023
- Author(s)
  Tateishi Yuki、Sato Ryo、Komatsu Shingo、Noguchi Masatsugu、Nagasawa Shota、Sasano Yusuke、Kanoh Naoki、Iwabuchi Yoshiharu
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 62 Issue: 29 Pages: 1-6
- DOI
  10.1002/anie.202303140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KJ0098, KAKENHI-PLANNED-21H05210, KAKENHI-PROJECT-23K24002, KAKENHI-PROJECT-23K27289
[Journal Article] Sequential click modification of a lithium-ion endohedral fullerene connecting small molecules through a dieneazide linker2023
- Author(s)
  Fujiki Shogo、Takada Takumi、Nagasawa Shota、Okada Hiroshi、Sasano Yusuke、Kwon Eunsang、Matsuo Yutaka、Iwabuchi Yoshiharu
- Journal Title
  
  Chemical Communications
  
  Volume: 59 Issue: 9 Pages: 1237-1240
- DOI
  10.1039/d2cc06301h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0087, KAKENHI-PROJECT-21K03520, KAKENHI-PLANNED-21H05210, KAKENHI-PROJECT-23K24002, KAKENHI-PROJECT-23K27289
[Journal Article] ortho-C_H Acetoxylation of Cubane Enabling Access to Cubane Analogues of Pharmaceutically Relevant Scaffolds2021
- Author(s)
  Shota Nagasawa, Masaki Hosaka, Yoshiharu Iwabuchi
- Journal Title
  
  Organic Letters
  
  Volume: 23 Issue: 22 Pages: 8717-8721
- DOI
  10.1021/acs.orglett.1c03144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03347, KAKENHI-PROJECT-21K15218
[Presentation] Cr-salen錯体/ニトロキシルラジカル協奏触媒系による分子内脱芳香族的o-pフェノールカップリングの開発2024
- Author(s)
  横田奈緒、長澤翔太、藤木翔吾、笹野裕介、岩渕好治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] Cr-salen触媒系によるレスベラトロール型スチルベノイドの空気酸化的二量化2024
- Author(s)
  板垣雄大、長澤翔太、笹野裕介、岩渕好治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] C-H Alkylation of Cubane via Catalytic Generation of Cubyl Radical2023
- Author(s)
  Masaki Hosaka, Shota Nagasawa, Yoshiharu Iwabuchi
- Organizer
  IKCOC-15 The 15th International Kyoto Conference on New Aspects of Organic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14315
[Presentation] Cr-salen/ニトロキシルラジカル触媒系による空気酸化的分子内脱芳香族的フェノールカップリング: 反応機構の詳細と不斉反応への展開2023
- Author(s)
  長澤翔太、藤木翔吾、笹野裕介、岩渕好治
- Organizer
  第56回酸化反応討論会
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] Total Synthesis of Cytotrienin A2023
- Author(s)
  Yuki Tateishi, Ryo Sato, Shingo Komatsu, Masatsugu Noguchi, Shota Nagasawa, Yusuke Sasano, Naoki Kanoh and Yoshiharu Iwabuchi
- Organizer
  ACS Meeting Fall 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] キュバン異性化の置換基効果を利用した二置換クネアンの選択的合成2023
- Author(s)
  藤原貫、長澤翔太、岩渕好治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K15218
[Presentation] Development of Cubane C-H alkylation via photocatalytic generation of cubyl radical2023
- Author(s)
  Masaki Hosaka, Shota Nagasawa, Yoshiharu Iwabuchi
- Organizer
  令和5年度化学系学協会東北大会及び日本化学会東北支部80周年記念国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14315
[Presentation] Selective Synthesis of 1,3-Substituted Cuneanes and Its Application to Bioisosteres of m-Substituted Benzenes2023
- Author(s)
  Shota Nagasawa, Kan Fujiwara, Rysei Maeyama, Ryosuke Segawa, Noriyasu Hirasawa, Takatsugu Hirokawa, Yoshiharu Iwabuchi
- Organizer
  IKCOC-15 The 15th International Kyoto Conference on New Aspects of Organic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14315
[Presentation] Stereoselective Synthesis of Benzoxanthenone Lignans Employing Chromium-salen/Nitroxyl Radical Cooperative Catalysis2023
- Author(s)
  Yudai Itagaki, Shota Nagasawa, Shogo Fujiki, Yusuke Sasano, Eunsang Kwon, Yoshiharu Iwabuchi
- Organizer
  IKCOC-15 The 15th International Kyoto Conference on New Aspects of Organic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] C-H活性化を介したキュバン骨格の新規アセトキシ化反応2022
- Author(s)
  保坂正樹、長澤翔太、岩渕好治
- Organizer
  第33回万有仙台シンポジウム
- Data Source
  KAKENHI-PROJECT-21K15218
[Presentation] クロムサレン錯体/ニトロキシルラジカル協奏触媒系による分子内脱芳香族的フェノールカップリングの開発とその応用2022
- Author(s)
  ○藤木翔吾、長澤翔太、笹野裕介、岩渕好治
- Organizer
  第38回有機合成化学セミナー
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] Highly Chemoselective Aerobic Alcohol Oxidation Co-catalyzed by Nitroxyl Radical and Copper2022
- Author(s)
  ○Yusuke Sasano, Shota Nagasawa, Naoki Kogure, Koki Kasabata, Yuhi Yoshida, Yoshiharu Iwabuchi
- Organizer
  The 11th Singapore International Chemistry Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] Cr-salen/ニトロキシルラジカル協奏触媒系を用いるベンゾキサンテノンリグナンの空気酸化的合成2022
- Author(s)
  ○板垣雄大、藤木翔吾、長澤翔太、笹野裕介、岩渕好治
- Organizer
  第11回JACI/GSCシンポジウム
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] クロム/ニトロキシルラジカル協奏触媒系による分子内脱芳香族的フェノールカップリングの不斉反応への展開2022
- Author(s)
  ○藤木翔吾、長澤翔太、笹野裕介、岩渕好治
- Organizer
  第20回次世代を担う有機化学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24002
[Presentation] C-H官能基化によるキュバン縮環型複素環化合物の合成研究2022
- Author(s)
  保坂正樹、長澤翔太、岩渕好治
- Organizer
  第51回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-21K15218
[Presentation] キュバンC-Hアセトキシ化反応の開発と応用2021
- Author(s)
  保坂正樹、長澤翔太、岩渕好治
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K15218
[Presentation] キュバンC-Hアセトキシ化反応の開発と応用2021
- Author(s)
  保坂正樹、長澤翔太、岩渕好治
- Organizer
  第60回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-21K15218

1. 岩渕好治 (20211766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 笹野裕介 (10636400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 山越博幸 (30596599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松尾豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGASAWA SHOTA 長澤 翔太

Nagasawa Shota 長澤 翔太

Research Projects

Research Products

Co-Researchers

キュバンの未踏医薬化学的ポテンシャルの開拓:beyond bioisosterePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高歪みかご型炭化水素の医薬化学的利用価値を拡張するための有機化学的方法論の開拓Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

有機ニトロキシルラジカルー遷移金属協奏触媒の機能創成を機軸とする精密有機分子構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transition-metal catalyzed C-H functionalization of cubane and its application to medicinal chemistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Radical-initiated C-H functionalization of cubane for medicinal chemistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] C-H Alkylation of Cubanes via Catalytic Generation of Cubyl Radicals2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Biological Evaluation of Isosteric Applicability of 1,3-Substituted Cuneanes as m-Substituted Benzenes Enabled by Selective Isomerization of 1,4-Substituted Cubanes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 4-Chloro-2-azaadamantane N-Oxyl (4-Cl-AZADO): A Readily Preparable Organocatalyst for NOx Co-catalyzed Aerobic Alcohol Oxidation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Asymmetric Total Synthesis of Cytotrienin A: Late‐Stage Installation of C11 Side Chain onto the Macrolactam Scaffold2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sequential click modification of a lithium-ion endohedral fullerene connecting small molecules through a dieneazide linker2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ortho-C_H Acetoxylation of Cubane Enabling Access to Cubane Analogues of Pharmaceutically Relevant Scaffolds2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Cr-salen錯体/ニトロキシルラジカル協奏触媒系による分子内脱芳香族的o-pフェノールカップリングの開発2024

Author(s)

Organizer

Data Source

[Presentation] Cr-salen触媒系によるレスベラトロール型スチルベノイドの空気酸化的二量化2024

Author(s)

Organizer

NAGASAWA SHOTA 長澤翔太

Nagasawa Shota 長澤翔太

[Presentation] Cr-salen/ニトロキシルラジカル触媒系による空気酸化的分子内脱芳香族的フェノールカップリング: 反応機構の詳細と不斉反応への展開2023