Kawakami Toru 川上徹

Researcher Number	50867041
Other IDs	https://orcid.org/0000-0003-0178-5332
Affiliation (Current)	2025: 独立行政法人国立病院機構まつもと医療センター(臨床研究部), 血液内科, 血液内科医師 2025: 独立行政法人国立病院機構まつもと医療センター(臨床研究部), 内科, 血液内科医師
Affiliation (based on the past Project Information) *help	2024: 独立行政法人国立病院機構まつもと医療センター(臨床研究部), 血液内科, 血液内科医師 2021 – 2023: 信州大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 赤芽球癆 / DNMT3A / TET2 / DNAメチル化 / T細胞受容体 / 体細胞遺伝子変異 / 自己免疫疾患 / T細胞 / ターゲットシーケンス / STAT3 / 胸腺腫 / クローン性造血

Elucidation of the pathogenesis of acquired pure red cell aplasiaby DNA methylation analysisPrincipal Investigator
- Principal Investigator
  
  川上徹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Hospital Organization Matsumoto Medical Center Clinical Research Department
Elucidation of immune abnormalities in thymoma and related autoimmune diseases through comprehensive genetic analysis of T cellsPrincipal Investigator
- Principal Investigator
  
  Kawakami Toru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shinshu University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Comparative analysis of humoral responses to BNT162b2 vaccine among patients with hematologic disorders and organ transplant recipients.2022
- Author(s)
  Nakazawa Hideyuki、Sakai Kaoko、Sudo Yuriko、Iwabuchi Ryohei、Sakai Hitoshi、Nishina Sayaka、Kawakami Toru、Kawakami Fumihiro、Matsuzawa Shuji、Ito Toshiro、Kitahara Mari、Kamijo Yuji、Umemura Takeji、Ushiki Atsuhito、Kanai Shinichiro、Tsuchiya Hiroyuki、Ishida Fumihiro
- Journal Title
  
  Transplant Immunology
  
  Volume: 75 Pages: 101713-101713
- DOI
  10.1016/j.trim.2022.101713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16302
[Journal Article] Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia2022
- Author(s)
  Huuhtanen Jani、Bhattacharya Dipabarna、Lonnberg Tapio、Kankainen Matti、Kerr Cassandra、Theodoropoulos Jason、Rajala Hanna、Gurnari Carmelo、Kasanen Tiina、Braun Till、Ishida Fumihiro、Kawakami Toru、Salmi Marko、Loughran Thomas、Maciejewski Jaroslaw P.、Lahdesmaki Harri、Kelkka Tiina、Mustjoki Satuら
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41467-022-29173-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16302
[Journal Article] Somatic mutations in acquired pure red cell aplasia2022
- Author(s)
  Kawakami Toru、Nakazawa Hideyuki、Ishida Fumihiro
- Journal Title
  
  Seminars in Hematology
  
  Volume: 59 Issue: 3 Pages: 131-136
- DOI
  10.1053/j.seminhematol.2022.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-20K08709
[Journal Article] Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia2022
- Author(s)
  Bhattacharya D, Teramo A, Gasparini VR, Huuhtanen J, Kim D, Theodoropoulos J, Schiavoni G, Barila G, Vicenzetto C, Calabretto G, Facco M, Kawakami T, Nakazawa H, Falini B, Tiacci E, Ishida F, Semenzato G, Kelkka T, Zambello R, Mustjoki S
- Journal Title
  
  Blood Cancer J
  
  Volume: 12 Issue: 2 Pages: 31-31
- DOI
  10.1038/s41408-022-00630-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08709, KAKENHI-PROJECT-21K16302
[Journal Article] T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia2022
- Author(s)
  Kawakami Fumihiro、Kawakami Toru、Yamane Taku、Maruyama Masae、Kobayashi Jun、Nishina Sayaka、Sakai Hitoshi、Higuchi Yumiko、Hamanaka Kazutoshi、Hirokawa Makoto、Nakao Shinji、Nakazawa Hideyuki、Ishida Fumihiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: ー Issue: 6 Pages: 816-825
- DOI
  10.1007/s12185-022-03310-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-20K08709
[Journal Article] Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia2022
- Author(s)
  Kelkka Tiina、Tyster Mikko、Lundgren Sofie、Feng Xingmin、Kerr Cassandra、Hosokawa Kohei、Huuhtanen Jani、Keranen Mikko、Patel Bhavisha、Kawakami Toruら
- Journal Title
  
  Leukemia
  
  Volume: 36 Issue: 9 Pages: 2317-2327
- DOI
  10.1038/s41375-022-01654-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-20K08709
[Journal Article] A novel germline GATA2 frameshift mutation with a premature stop codon in a family with congenital sensory hearing loss and myelodysplastic syndrome2021
- Author(s)
  Nakazawa Hideyuki、Yamaguchi Tomomi、Sakai Hitoshi、Maruyama Masae、Kawakami Toru、Kawakami Fumihiro、Nishina Sayaka、Ishikawa Masumi、Kosho Tomoki、Ishida Fumihiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 2 Pages: 286-291
- DOI
  10.1007/s12185-021-03130-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16302
[Presentation] 大顆粒リンパ球白血病における遺伝子変異プロファイルと臨床像との関連2023
- Author(s)
  川上徹
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16302
[Presentation] Characteristic mutational profiles of STAT3 and clonal hematopoiesis-related genes in acquired PRCA2022
- Author(s)
  Toru Kawakami, Taku Yamane, Fumihiro Kawakami, Masae Maruyama, Natsumi Ida, Yuga Mizuno, Ami Asakura, Sayaka Nishina, Hitoshi Sakai, Yumiko Higuchi, Hideyuki Nakazawa, Fumihiro Ishida
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16302
[Presentation] Clonal T-cell expansion and STAT3 mutations in T-cell mediated acquired pure red cell aplasia2021
- Author(s)
  Fumihiro Kawakami、Toru Kawakami、Taku Yamane、Jun Kobayashi、Sayaka Nishina、Hitoshi Sakai、Yumiko Higuchi、Makoto Hirokawa、Shinji Nakao、Hideyuki Nakazawa、Fumihiro Ishida
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16302

1. 石田文宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawakami Toru 川上 徹

Research Projects

Research Products

Co-Researchers

Elucidation of the pathogenesis of acquired pure red cell aplasiaby DNA methylation analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of immune abnormalities in thymoma and related autoimmune diseases through comprehensive genetic analysis of T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comparative analysis of humoral responses to BNT162b2 vaccine among patients with hematologic disorders and organ transplant recipients.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Somatic mutations in acquired pure red cell aplasia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel germline GATA2 frameshift mutation with a premature stop codon in a family with congenital sensory hearing loss and myelodysplastic syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 大顆粒リンパ球白血病における遺伝子変異プロファイルと臨床像との関連2023

Author(s)

Organizer

Data Source

[Presentation] Characteristic mutational profiles of STAT3 and clonal hematopoiesis-related genes in acquired PRCA2022

Author(s)

Organizer

Data Source

[Presentation] Clonal T-cell expansion and STAT3 mutations in T-cell mediated acquired pure red cell aplasia2021

Author(s)

Organizer

Data Source

Kawakami Toru 川上徹