Miyahara Satoshi 宮原敏

Researcher Number	50878329
Other IDs	https://orcid.org/0000-0001-8522-860X
Affiliation (Current)	2025: 産業医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 医学部, 講師 2020 – 2023: 産業医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / 0904:Internal medicine of the bio-information integration and related fields Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator レプトスピラ症 / 病原因子 / 黄疸 / 肝臓スフェロイド / 感染症 / 肝細胞 / スフェロイド / 腎不全 / ハムスターモデル / 病理学 … More / 人獣共通感染症 / 動物モデル / 慢性腎臓病 / 急性腎障害 / ワイル病 … More Except Principal Investigator 局所高濃度抗菌薬持続灌流 / アミノグリコシド耐性 / アミノグリコシド耐性遺伝子 / 持続局所抗菌薬灌流療法 / 持続局所抗菌薬潅流療法 / 骨軟部組織感染症 / 耐性遺伝子 / ゲンタマイシン / メチシリン耐性黄色ブドウ球菌 / 持続局所抗菌薬潅流 / 骨軟部感染症 / アミノグリコシド系耐性遺伝子 / 最小発育阻止濃度 / 最小バイオフィルム撲滅濃度 / MRSA / 耐性菌 / バイオフィルム Less

Analysis of the pathogenesis of icteric leptospirosis using human liver spheroidsPrincipal Investigator
- Principal Investigator
  
  宮原敏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Microbiological validation for optimization of sustained local antibiotic perfusion therapy for MRSA bone and soft tissue infections
- Principal Investigator
  
  Zenke Yukichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Mechanisms of Severe Leptospira Infection Focusing on Bacterial Dynamics and Histopathological Changes in the HostPrincipal Investigator
- Principal Investigator
  
  Miyahara Satoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 【腎臓症候群(第3版)-その他の腎臓疾患を含めて-】各種病態にみられる腎障害感染症レプトスピラ感染症(Weil病)2022
- Author(s)
  齋藤光正、丸岡司、二階堂靖彦、宮原敏
- Total Pages
  5
- Publisher
  (株)日本臨床社
- Data Source
  KAKENHI-PROJECT-22K16381
[Book] 【CLAPによる骨軟部感染抑制の実際】CLAPの構築方法ゲンタマイシンの作用機序と薬剤耐性機構2022
- Author(s)
  齋藤光正、宮原敏、安藤恒平、善家雄吉
- Total Pages
  6
- Publisher
  (株)全日本病院出版会
- Data Source
  KAKENHI-PROJECT-22K16381
[Journal Article] Non-purulent myositis caused by direct invasion of skeletal muscle tissue by <i>Leptospira</i> in a hamster model2024
- Author(s)
  Miyahara Satoshi、Mori Hiroshi、Fukuda Kazumasa、Ogawa Midori、Saito Mitsumasa
- Journal Title
  
  Infection and Immunity
  
  Volume: 92 Issue: 2
- DOI
  10.1128/iai.00420-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16381
[Journal Article] Protective role of stratum corneum in percutaneous Leptospira infection in a hamster model2023
- Author(s)
  Asoh Tatsuma、Miyahara Satoshi、Villanueva Sharon Yvette Angelina M.、Kanemaru Takaaki、Takigawa Tomoya、Mori Hiroshi、Gloriani Nina G.、Yoshida Shin-ichi、Saito Mitsumasa
- Journal Title
  
  Microbial Pathogenesis
  
  Volume: 182 Pages: 106243-106243
- DOI
  10.1016/j.micpath.2023.106243
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16381
[Journal Article] Detection system for Legionella bacteria using photogate-type optical sensor2022
- Author(s)
  Honda Yuto、Ichikawa Ryosuke、Choi Yong Joon、Murakami Kensuke、Takahashi Kazuhiro、Noda Toshihiko、Sawada Kazuaki、Ishii Hiromu、Machida Katsuyuki、Ito Hiroyuki、Miyahara Satoshi、Nikaido Yasuhiko、Saito Mitsumasa
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 61 Issue: SD Pages: SD1010-SD1010
- DOI
  10.35848/1347-4065/ac5a25
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942, KAKENHI-PROJECT-19H02196, KAKENHI-PROJECT-20K14790
[Journal Article] Dissemination of Leptospira into the intestinal tract resulting in fecal excretion in a hamster model of subcutaneous infection with Leptospira interrogans2022
- Author(s)
  Inamasu Yoshinori、Nikaido Yasuhiko、Miyahara Satoshi、Maruoka Tsukasa、Takigawa Tomoya、Ogawa Midori、Nakayama Toshiyuki、Harada Masaru、Saito Mitsumasa
- Journal Title
  
  Microbial Pathogenesis
  
  Volume: 165 Pages: 105481-105481
- DOI
  10.1016/j.micpath.2022.105481
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942, KAKENHI-PROJECT-21K07926
[Journal Article] A machine learning model of microscopic agglutination test for diagnosis of leptospirosis2021
- Author(s)
  Oyamada Yuji、Ozuru Ryo、Masuzawa Toshiyuki、Miyahara Satoshi、Nikaido Yasuhiko、Obata Fumiko、Saito Mitsumasa、Villanueva Sharon Yvette Angelina M.、Fujii Jun
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: e0259907-e0259907
- DOI
  10.1371/journal.pone.0259907
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942, KAKENHI-PROJECT-21K16320
[Journal Article] Correlation between renal distribution of leptospires during the acute phase and chronic renal dysfunction in a hamster model of infection with Leptospira interrogans2021
- Author(s)
  Maruoka Tsukasa、Nikaido Yasuhiko、Miyahara Satoshi、Katafuchi Eisuke、Inamasu Yoshinori、Ogawa Midori、Fukuda Kazumasa、Nakayama Toshiyuki、Horishita Takafumi、Saito Mitsumasa
- Journal Title
  
  PLOS Neglected Tropical Diseases
  
  Volume: 15 Issue: 6 Pages: e0009410-e0009410
- DOI
  10.1371/journal.pntd.0009410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942
[Journal Article] A Machine Learning Approach Towards Standardizing Microscopic Agglutination Test for Diagnosis of Leptospirosis2020
- Author(s)
  Oyamada Yuji、Ozuru Ryo、Masuzawa Toshiyuki、Miyahara Satoshi、Nikaido Yasuhiko、Obata Fumiko、Saito Mitsumasa、Villanueva Sharon Yvette Angelina M.、Fujii Jun
- Journal Title
  
  bioRxiv
  
  Volume: - Pages: 410712-410712
- DOI
  10.1101/2020.12.08.410712
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942, KAKENHI-PROJECT-18K16174
[Presentation] Non-purulent myositis caused by direct invasion of skeletal muscle tissue by Leptospira in a hamster model.2024
- Author(s)
  Satoshi Miyahara
- Organizer
  The Biology of Spirochetes, Gordon Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] メチシリン耐性黄色ブドウ球菌臨床分離株に対するゲンタマイシンの最小バイオフィルム撲滅濃度と耐性遺伝子との関連2023
- Author(s)
  安藤恒平善家雄吉宮原敏
- Organizer
  第38回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09241
[Presentation] ハムスターを用いたJarisch-Herxheimer反応モデルの作製2023
- Author(s)
  宮原敏、森博士、齋藤光正
- Organizer
  第59回レプトスピラ・シンポジウム
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] レプトスピラ感染症に対する国際共同研究の展開2023
- Author(s)
  宮原敏
- Organizer
  第16回グローカル感染症研究セミナー
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] ROLES OF MACROPHAGES ON THE PATHOGENESIS OF LEPTOSPIRA INFECTION- INDUCED MYOSITIS2022
- Author(s)
  Satoshi Miyahara, Mitsumasa Saito
- Organizer
  The 12th Meeting of The International Leptospirosis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] ハムスターモデルを用いたレプトスピラ症に伴う筋炎の病態解析2022
- Author(s)
  宮原敏、齋藤光正
- Organizer
  第58回レプトスピラシンポジウム
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] レプトスピラ感染ハムスターモデルにおける消化管の解析と糞便からの同菌分離2022
- Author(s)
  稲益良紀、二階堂靖彦、宮原敏、丸岡司、瀧川友哉、小川みどり、福田和正、齋藤光正
- Organizer
  第58回レプトスピラシンポジウム
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] DEEP LEARNING-BASED AGGLUTINATION RATE ESTIMATION FOR MICROSCOPIC AGGLUTINATION TEST2022
- Author(s)
  ◎Risa Nakano, Yuji Oyamada, Ryo Ozuru, Satoshi Miyahara, Michinobu Yoshimura, and Kenji Hiromatsu
- Organizer
  The 12th Meeting of The International Leptospirosis Society
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] 深層学習モデルによる顕微鏡下凝集試験の凝集率推定とその応用2022
- Author(s)
  中野里咲、小山田雄仁、尾鶴亮、宮原敏、吉村芳修、齋藤光正、廣松賢治
- Organizer
  第58回レプトスピラシンポジウム
- Data Source
  KAKENHI-PROJECT-22K16381
[Presentation] 細菌検査を自動化するーレプトスピラ症の顕微鏡下凝集試験（Microscopic Agglutination Test; MAT）を例に2021
- Author(s)
  尾鶴亮、小山田雄仁、増澤俊之、宮原敏、二階堂靖彦、齋藤光正、Sharon Y. A. M. Villanueva、藤井潤
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] ハムスターモデルにおけるレプトスピラ症と慢性腎機能低下の関係性2021
- Author(s)
  丸岡司, 宮原敏, 福田和正, 小川みどり, 齋藤光正
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] ハムスターモデルにおけるレプトスピラ症と慢性腎機能低下の関係性2021
- Author(s)
  丸岡司、宮原敏、福田和正、小川みどり、齋藤光正
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] Detection system of bacteria, Legionella by photogate type optical sensor2021
- Author(s)
  Yuto Honda, Yong-Joon Choi, Kensuke Murakami, Kazuhiro Takahashi, Toshihiko Noda, Kazuaki Sawada, Hiromu Ishii, Katsuyuki Machida, Hiroyuki Ito, Satoshi Miyahara, Yasuhiko Nikaido and Mitsumasa Saito
- Organizer
  34th International Microprocesses and Nanotechnology Conference (MNC 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] レプトスピラ感染ハムスターモデルでの糞便排出を伴った消化管の解析2021
- Author(s)
  稲益良紀, 二階堂靖彦, 宮原敏, 丸岡司, 瀧川友哉, 小川みどり, 福田和正, 齋藤光正
- Organizer
  九州微生物研究フォーラム2021
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] 免疫不全マウスを用いた新たな劇症型溶血性レンサ球菌感染症マウスモデルの開発2021
- Author(s)
  辻高寛, 小幡史子, 尾鶴亮, 宮原敏, 齋藤光正, 藤井潤
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] 免疫不全マウスを用いた新たな劇症型溶血性連鎖球菌感染症マウスモデルの開発2021
- Author(s)
  辻高寛、小幡史子、尾鶴亮、宮原敏、齋藤光正、藤井潤
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942
[Presentation] 細菌検査を自動化するーレプトスピラ症の顕微鏡下業種試験(Micropcopic Agglutination test; MAT）を例に2021
- Author(s)
  尾鶴亮, 小山田雄仁, 増澤俊幸, 宮原敏, 二階堂靖彦, 齋藤光正, Sharon Y. A. M. Villanueva, 藤井潤
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K22942

1. Zenke Yukichi (80615930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 安藤恒平 (80899518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 齋藤光正 (00315087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 濱田大志 (20899306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 石川成人 (50848314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 佐藤直人 (20912968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 眞田彩華 (10887045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 酒井昭典 (90248576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 真弓俊彦 (90281071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miyahara Satoshi 宮原 敏

Research Projects

Research Products

Co-Researchers

Analysis of the pathogenesis of icteric leptospirosis using human liver spheroidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Microbiological validation for optimization of sustained local antibiotic perfusion therapy for MRSA bone and soft tissue infections

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of Severe Leptospira Infection Focusing on Bacterial Dynamics and Histopathological Changes in the HostPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 【腎臓症候群(第3版)-その他の腎臓疾患を含めて-】各種病態にみられる腎障害 感染症 レプトスピラ感染症(Weil病)2022

Author(s)

Total Pages

Publisher

Data Source

[Book] 【CLAPによる骨軟部感染抑制の実際】CLAPの構築方法 ゲンタマイシンの作用機序と薬剤耐性機構2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Non-purulent myositis caused by direct invasion of skeletal muscle tissue by <i>Leptospira</i> in a hamster model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective role of stratum corneum in percutaneous Leptospira infection in a hamster model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection system for Legionella bacteria using photogate-type optical sensor2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dissemination of Leptospira into the intestinal tract resulting in fecal excretion in a hamster model of subcutaneous infection with Leptospira interrogans2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A machine learning model of microscopic agglutination test for diagnosis of leptospirosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation between renal distribution of leptospires during the acute phase and chronic renal dysfunction in a hamster model of infection with Leptospira interrogans2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Machine Learning Approach Towards Standardizing Microscopic Agglutination Test for Diagnosis of Leptospirosis2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Non-purulent myositis caused by direct invasion of skeletal muscle tissue by Leptospira in a hamster model.2024

Author(s)

Organizer

Data Source

[Presentation] メチシリン耐性黄色ブドウ球菌臨床分離株に対するゲンタマイシンの最小バイオフィルム撲滅濃度と耐性遺伝子との関連2023

Author(s)

Organizer

Data Source

[Presentation] ハムスターを用いたJarisch-Herxheimer反応モデルの作製2023

Author(s)

Organizer

Data Source

[Presentation] レプトスピラ感染症に対する国際共同研究の展開2023

Miyahara Satoshi 宮原敏

[Book] 【腎臓症候群(第3版)-その他の腎臓疾患を含めて-】各種病態にみられる腎障害感染症レプトスピラ感染症(Weil病)2022

[Book] 【CLAPによる骨軟部感染抑制の実際】CLAPの構築方法ゲンタマイシンの作用機序と薬剤耐性機構2022