Putu Prathiwi Primadharsini Ｐｕｔｕ・Ｐｒａｔｈｉｗｉ・Ｐｒｉｍａｄｈａｒｓｉｎｉ

… Alternative Names

プトゥ・プラティウィ・プリマダルシニプトゥ・プラティウィ・プリマダルシニ

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Researcher Number	50880100
Affiliation (Current)	2025: 自治医科大学, 医学部, ポスト・ドクター
Affiliation (based on the past Project Information) *help	2020 – 2023: 自治医科大学, 医学部, ポスト・ドクター
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator Drug screening / Hepatitis E virus / Virus replication / Small compound screening / Host factor / Cellular permissiveness / Reporter virus / Replication efficiency / Cell culture / Microarray … More / Anti-HEV drug / Host cellular factor / Cell-culture / Drug-screening / Bioluminescence / drug screening / quasi-enveloped HEV / non-enveloped HEV / hypervariable region / nanoKAZ / reporter virus / bioluminescent / hepatitis E virus Less

Elucidation of host factors and the associated pathways responsible for cellular permissiveness to hepatitis E virus replication and identification of the potential inhibitorsPrincipal Investigator
- Principal Investigator
  
  Primadharsini Putu Prathiwi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Jichi Medical University
Production of infectious hepatitis E virus (HEV) harboring bioluminescent reporter gene for comprehensive screening of antiviral drugs against HEV and ex vivo evaluation of selected drugsPrincipal Investigator
- Principal Investigator
  
  Putu Prathiwi Primadharsini
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Jichi Medical University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Three Distinct Reporter Systems of Hepatitis E Virus and Their Utility as Drug Screening Platforms2023
- Author(s)
  Primadharsini Putu Prathiwi、Nagashima Shigeo、Nishiyama Takashi、Okamoto Hiroaki
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 10 Pages: 1989-1989
- DOI
  10.3390/v15101989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K15478
[Journal Article] Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone2023
- Author(s)
  Primadharsini Putu Prathiwi、Nagashima Shigeo、Tanaka Toshinori、Jirintai Suljid、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 4 Pages: 845-845
- DOI
  10.3390/v15040845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K15478, KAKENHI-PROJECT-22K07991
[Journal Article] Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform2023
- Author(s)
  Nagashima Shigeo、Primadharsini Putu Prathiwi、Nishiyama Takashi、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 9
- DOI
  10.1128/jvi.00508-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
[Journal Article] Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 20212023
- Author(s)
  Takahashi Masaharu、Kunita Satoshi、Nishizawa Tsutomu、Ohnishi Hiroshi、Primadharsini Putu Prathiwi、Nagashima Shigeo、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 7 Pages: 1516-1516
- DOI
  10.3390/v15071516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
[Journal Article] Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin2022
- Author(s)
  Primadharsini Putu Prathiwi、Nagashima Shigeo、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 11 Pages: 2440-2440
- DOI
  10.3390/v14112440
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
[Journal Article] Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening2022
- Author(s)
  Primadharsini Putu Prathiwi、Nagashima Shigeo、Nishiyama Takashi、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 6
- DOI
  10.1128/jvi.01906-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
[Journal Article] Production of capsid proteins of rat hepatitis E virus in Escherichia coli and characterization of self-assembled virus-like particles2021
- Author(s)
  Kobayashi Tominari、Takahashi Masaharu、Ohta Satoshi、Nagashima Shigeo、Primadharsini Putu Prathiwi、Mulyanto、Kunita Satoshi、Murata Kazumoto、Okamoto Hiroaki
- Journal Title
  
  Virus Research
  
  Volume: 302 Pages: 198483-198483
- DOI
  10.1016/j.virusres.2021.198483
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
[Journal Article] Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus2021
- Author(s)
  Primadharsini Putu Prathiwi、Nagashima Shigeo、Okamoto Hiroaki
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 5 Pages: 909-909
- DOI
  10.3390/v13050909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
[Presentation] Analysis of host factors underlying cellular susceptibility to hepatitis E virus replication2023
- Author(s)
  Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
- Organizer
  The 70th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-22K15478
[Presentation] Analysis of ritonavir inhibition target in hepatitis E virus life cycle and the efficacy of its combination with ribavirin in cultured cells2022
- Author(s)
  Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
- Organizer
  The 69th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-22K15478
[Presentation] Development of recombinant hepatitis E virus harboring nanoKAZ gene and its application to drug screening2021
- Author(s)
  Putu Prathiwi Primadharsini, Shigeo Nagashima, Takashi Nishiyama, Masaharu Takahashi, Hiroaki Okamoto, Kazumoto Murata
- Organizer
  The 68th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-20K22771

1. NAGASHIMA Shigeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

Putu Prathiwi Primadharsini Ｐｕｔｕ・Ｐｒａｔｈｉｗｉ・Ｐｒｉｍａｄｈａｒｓｉｎｉ

プトゥ・プラティウィ・プリマダルシニ プトゥ・プラティウィ・プリマダルシニ

Research Projects

Research Products

Co-Researchers

Elucidation of host factors and the associated pathways responsible for cellular permissiveness to hepatitis E virus replication and identification of the potential inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production of infectious hepatitis E virus (HEV) harboring bioluminescent reporter gene for comprehensive screening of antiviral drugs against HEV and ex vivo evaluation of selected drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Three Distinct Reporter Systems of Hepatitis E Virus and Their Utility as Drug Screening Platforms2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 20212023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Production of capsid proteins of rat hepatitis E virus in Escherichia coli and characterization of self-assembled virus-like particles2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Analysis of host factors underlying cellular susceptibility to hepatitis E virus replication2023

Author(s)

Organizer

Data Source

[Presentation] Analysis of ritonavir inhibition target in hepatitis E virus life cycle and the efficacy of its combination with ribavirin in cultured cells2022

Author(s)

Organizer

Data Source

[Presentation] Development of recombinant hepatitis E virus harboring nanoKAZ gene and its application to drug screening2021

Author(s)

Organizer

Data Source

プトゥ・プラティウィ・プリマダルシニプトゥ・プラティウィ・プリマダルシニ