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Putu Prathiwi Primadharsini  Putu・Prathiwi・Primadharsini

ORCIDConnect your ORCID iD *help
… Alternative Names

プトゥ・プラティウィ・プリマダルシニ  プトゥ・プラティウィ・プリマダルシニ

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Researcher Number 50880100
Affiliation (Current) 2025: 自治医科大学, 医学部, ポスト・ドクター
Affiliation (based on the past Project Information) *help 2020 – 2023: 自治医科大学, 医学部, ポスト・ドクター
Review Section/Research Field
Principal Investigator
Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields
Keywords
Principal Investigator
Drug screening / Hepatitis E virus / Virus replication / Small compound screening / Host factor / Cellular permissiveness / Reporter virus / Replication efficiency / Cell culture / Microarray … More / Anti-HEV drug / Host cellular factor / Cell-culture / Drug-screening / Bioluminescence / drug screening / quasi-enveloped HEV / non-enveloped HEV / hypervariable region / nanoKAZ / reporter virus / bioluminescent / hepatitis E virus Less
  • Research Projects

    (2 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (1 People)
  •  Elucidation of host factors and the associated pathways responsible for cellular permissiveness to hepatitis E virus replication and identification of the potential inhibitorsPrincipal Investigator

    • Principal Investigator
      Primadharsini Putu Prathiwi
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Jichi Medical University
  •  Production of infectious hepatitis E virus (HEV) harboring bioluminescent reporter gene for comprehensive screening of antiviral drugs against HEV and ex vivo evaluation of selected drugsPrincipal Investigator

    • Principal Investigator
      Putu Prathiwi Primadharsini
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0803:Pathology, infection/immunology, and related fields
    • Research Institution
      Jichi Medical University

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Three Distinct Reporter Systems of Hepatitis E Virus and Their Utility as Drug Screening Platforms2023

    • Author(s)
      Primadharsini Putu Prathiwi、Nagashima Shigeo、Nishiyama Takashi、Okamoto Hiroaki
    • Journal Title

      Viruses

      Volume: 15 Issue: 10 Pages: 1989-1989

    • DOI

      10.3390/v15101989

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K15478
  • [Journal Article] Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone2023

    • Author(s)
      Primadharsini Putu Prathiwi、Nagashima Shigeo、Tanaka Toshinori、Jirintai Suljid、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Viruses

      Volume: 15 Issue: 4 Pages: 845-845

    • DOI

      10.3390/v15040845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K15478, KAKENHI-PROJECT-22K07991
  • [Journal Article] Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform2023

    • Author(s)
      Nagashima Shigeo、Primadharsini Putu Prathiwi、Nishiyama Takashi、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Journal of Virology

      Volume: 97 Issue: 9

    • DOI

      10.1128/jvi.00508-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
  • [Journal Article] Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 20212023

    • Author(s)
      Takahashi Masaharu、Kunita Satoshi、Nishizawa Tsutomu、Ohnishi Hiroshi、Primadharsini Putu Prathiwi、Nagashima Shigeo、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Viruses

      Volume: 15 Issue: 7 Pages: 1516-1516

    • DOI

      10.3390/v15071516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
  • [Journal Article] Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin2022

    • Author(s)
      Primadharsini Putu Prathiwi、Nagashima Shigeo、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Viruses

      Volume: 14 Issue: 11 Pages: 2440-2440

    • DOI

      10.3390/v14112440

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07105, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K15478
  • [Journal Article] Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening2022

    • Author(s)
      Primadharsini Putu Prathiwi、Nagashima Shigeo、Nishiyama Takashi、Takahashi Masaharu、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Journal of Virology

      Volume: 96 Issue: 6

    • DOI

      10.1128/jvi.01906-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
  • [Journal Article] Production of capsid proteins of rat hepatitis E virus in Escherichia coli and characterization of self-assembled virus-like particles2021

    • Author(s)
      Kobayashi Tominari、Takahashi Masaharu、Ohta Satoshi、Nagashima Shigeo、Primadharsini Putu Prathiwi、Mulyanto、Kunita Satoshi、Murata Kazumoto、Okamoto Hiroaki
    • Journal Title

      Virus Research

      Volume: 302 Pages: 198483-198483

    • DOI

      10.1016/j.virusres.2021.198483

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
  • [Journal Article] Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus2021

    • Author(s)
      Primadharsini Putu Prathiwi、Nagashima Shigeo、Okamoto Hiroaki
    • Journal Title

      Viruses

      Volume: 13 Issue: 5 Pages: 909-909

    • DOI

      10.3390/v13050909

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07579, KAKENHI-PROJECT-20K22771
  • [Presentation] Analysis of host factors underlying cellular susceptibility to hepatitis E virus replication2023

    • Author(s)
      Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
    • Organizer
      The 70th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-22K15478
  • [Presentation] Analysis of ritonavir inhibition target in hepatitis E virus life cycle and the efficacy of its combination with ribavirin in cultured cells2022

    • Author(s)
      Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
    • Organizer
      The 69th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-22K15478
  • [Presentation] Development of recombinant hepatitis E virus harboring nanoKAZ gene and its application to drug screening2021

    • Author(s)
      Putu Prathiwi Primadharsini, Shigeo Nagashima, Takashi Nishiyama, Masaharu Takahashi, Hiroaki Okamoto, Kazumoto Murata
    • Organizer
      The 68th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-20K22771
  • 1.  NAGASHIMA Shigeo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results

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