• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Furuhata Takafumi  古畑 隆史

ORCIDConnect your ORCID iD *help
Researcher Number 50882635
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院工学系研究科(工学部), 助教
Affiliation (based on the past Project Information) *help 2020 – 2024: 東京大学, 大学院工学系研究科(工学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 37010:Bio-related chemistry / Transformative Research Areas, Section (III) / 0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
Keywords
Principal Investigator
ユビキチン / 不均一鎖 / "ライブラリ×ライブラリ" / 相互作用 / DNAバーコーディング / シャトル因子 / 直列型 / タンパク質標的分解 / 光分解性保護基 / 段階的伸長 … More / ポリユビキチン / ワンポット合成 / プロテアソーム / 分岐構造制御 / 分岐位置 / 光制御 / ワンポット / 分岐鎖 / ホルミル修飾 / DNA / クロマチン / スライディング / ポジショニング / ヌクレオソーム / ホルミル化 / DNA修飾 Less
  • Research Projects

    (4 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (1 People)
  •  主鎖で連結した直列型ユビキチン鎖の非酵素的修飾を介したタンパク質標的分解Principal Investigator

    • Principal Investigator
      古畑 隆史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  'Library-against-library' interaction analysis of heterotypic polyubiquitin chains and shuttle factors.Principal Investigator

    • Principal Investigator
      古畑 隆史
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  Photo-controlled stepwise elongation to synthesize branched polyubiquitin chains for studying their structure-function relationshipsPrincipal Investigator

    • Principal Investigator
      Furuhata Takafumi
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Regulation of biochemical reactions on DNA through structural control of chromatin by DNA formylationPrincipal Investigator

    • Principal Investigator
      Furuhata Takafumi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
    • Research Institution
      The University of Tokyo

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] One-Pot, Photocontrolled Enzymatic Assembly of the Structure-Defined Heterotypic Polyubiquitin Chain2023

    • Author(s)
      Furuhata, T.; Racheal, P. A. D.; Murayama, I.; Toyoda, U.; Okamoto, A.
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 145 Pages: 11690-11700

    • DOI

      10.1021/jacs.3c01912

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K17969, KAKENHI-PROJECT-22K14778, KAKENHI-WRAPUP-23H05424, KAKENHI-PUBLICLY-23H04253, KAKENHI-PROJECT-23H00317
  • [Presentation] Exploration of peptide-based degraders for chemical protein knockdown via noncovalent ubiquitination2024

    • Author(s)
      Jotaro Miyamoto, Kazuki Yoshida, Takafumi Furuhata, Akimitsu Okamoto
    • Organizer
      The 3rd International Symposium on Biofunctional Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K14778
  • [Presentation] Exploration of peptide-based degraders for chemical protein knockdown via noncovalent ubiquitination2024

    • Author(s)
      Jotaro Miyamoto, Kazuki Yoshida, Takafumi Furuhata, Akimitsu Okamoto
    • Organizer
      第19回バイオ関連 化学シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-23H04253
  • [Presentation] 不均一鎖の近位ユビキチンC末端への 多様な化学修飾の導入2024

    • Author(s)
      古畑隆史、崔汎圭、宇野大輝、 佐藤裕介、尾勝圭、深井周也、岡本晃充
    • Organizer
      日本化学会第104春期年会
    • Data Source
      KAKENHI-PUBLICLY-23H04253
  • [Presentation] オキシム連結反応を用いた不均一ユビキチン鎖の 構造制御合成2024

    • Author(s)
      篠原 陵大、古畑 隆史、山田 征吾、岡本 晃充
    • Organizer
      日本化学会第104春期年会
    • Data Source
      KAKENHI-PROJECT-22K14778
  • [Presentation] オキシム連結反応を用いた不均一ユビキチン鎖の 構造制御合成2024

    • Author(s)
      篠原 陵大、古畑 隆史、山田 征吾、岡本 晃充
    • Organizer
      日本化学会第104春期年会
    • Data Source
      KAKENHI-PUBLICLY-23H04253
  • [Presentation] タンパク質分解経路の制御を指向した新規ケミカルノックダウン法の確立2024

    • Author(s)
      吉田 和生、古畑 隆史、土屋 光、佐伯 泰、岡本 晃充
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PUBLICLY-23H04253
  • [Presentation] 分岐構造を規定した不均一ポリユビキチン鎖の ワンポット構築2023

    • Author(s)
      古畑隆史、Phebee Angeline Devadasan Racheal、冨田拓哉、佐藤裕介、尾勝圭、 村山 伊織、豊田宇咲乃、深井 周也、佐伯 泰、岡本晃充
    • Organizer
      第19回バイオ関連 化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-22K14778
  • [Presentation] ペプチド型ユビキチンリガンドキメラを用いた標的タンパク質分解2023

    • Author(s)
      宮本 丈太郎、吉田 和生、古畑 隆史、岡本 晃充
    • Organizer
      第13回CSJ化学フェスタ2023
    • Data Source
      KAKENHI-PROJECT-22K14778
  • [Presentation] 分岐構造を規定した不均一ポリユビキチン鎖の ワンポット構築2023

    • Author(s)
      古畑隆史、Phebee Angeline Devadasan Racheal、冨田拓哉、佐藤裕介、尾勝圭、 村山 伊織、豊田宇咲乃、深井 周也、佐伯 泰、岡本晃充
    • Organizer
      第19回バイオ関連 化学シンポジウム
    • Data Source
      KAKENHI-PUBLICLY-23H04253
  • [Presentation] One-pot controlled synthesis of heterotypic polyubiquitin by photo-controlled enzymatic chain assembly2022

    • Author(s)
      古畑 隆史
    • Organizer
      Ubiquitin New Frontier "from Neo-Biology to Targeted Protein Degradation"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K14778
  • 1.  岡本 晃充
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi