Ito Takeshi 伊藤剛

… Alternative Names

伊藤剛イトウタケシ

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Researcher Number	50897733
Other IDs
Affiliation (Current)	2025: 愛媛大学, 農学研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 愛媛大学, 農学研究科, 助教 2022: 徳島大学, 先端酵素学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 38040:Bioorganic chemistry-related
Keywords	Principal Investigator ケミカルバイオロジー / 阻害剤 / リンゴ酸-キノン酸化還元酵素 / 触媒機構 / 異種発現 / マラリア原虫 / TCA回路 / リンゴ酸－キノン酸化還元酵素 / ミトコンドリア

Research Projects
(1 results)
Research Products
(11 results)

Expression of malaria parasite mitochondrial protein in yeast and design of novel antimalarial compoundsPrincipal Investigator
- Principal Investigator
  
  伊藤剛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Ehime University
  The University of Tokushima

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Unique Behavior of Bacterially Expressed Rat Carnitine Palmitoyltransferase 2 and Its Catalytic Activity2024
- Author(s)
  Akieda Kiri、Takegawa Kazuto、Ito Takeshi、Nagayama Gaku、Yamazaki Naoshi、Nagasaki Yuka、Nishino Kohei、Kosako Hidetaka、Shinohara Yasuo
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 1 Pages: 23-27
- DOI
  10.1248/bpb.b23-00612
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14838
[Journal Article] Insights into the Mechanism of Catalytic Activity of Plasmodium Parasite Malate-Quinone Oxidoreductase2024
- Author(s)
  Ito Takeshi、Tojo Yuma、Fujii Minori、Nishino Kohei、Kosako Hidetaka、Shinohara Yasuo
- Journal Title
  
  ACS Omega
  
  Volume: － Issue: 19 Pages: 21647-21657
- DOI
  10.1021/acsomega.4c02614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14838
[Journal Article] KH-17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane2023
- Author(s)
  Takegawa Kazuto、Ito Takeshi、Yamamoto Atsushi、Yamazaki Naoshi、Shindo Mitsuru、Shinohara Yasuo
- Journal Title
  
  Chemical Biology and Drug Design
  
  Volume: 101 Issue: 4 Pages: 865-872
- DOI
  10.1111/cbdd.14194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K14838, KAKENHI-PROJECT-20K21198, KAKENHI-PROJECT-23K17919, KAKENHI-PROJECT-23K24007
[Journal Article] Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase2023
- Author(s)
  Ito Takeshi、Kajita Sayaka、Fujii Minori、Shinohara Yasuo
- Journal Title
  
  Microbiology Spectrum
  
  Volume: － Issue: 3
- DOI
  10.1128/spectrum.00168-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14838
[Journal Article] Bacteroides fragilis Maintains Concurrent Capability for Anaerobic and Nanaerobic Respiration2023
- Author(s)
  Butler Nicole L.、Ito Takeshi、Foreman Sara、Morgan Joel E.、Zagorevsky Dmitry、Malamy Michael H.、Comstock Laurie E.、Barquera Blanca
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 205 Issue: 1
- DOI
  10.1128/jb.00389-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] マラリア原虫リンゴ酸－キノン酸化還元酵素は酵母ミトコンドリアで機能発現する2023
- Author(s)
  伊藤剛、梶田彩、藤井みのり、篠原康雄
- Organizer
  日本農芸化学会 2023年度大会
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] 褐色脂肪組織を特徴づけるタンパク質の発現レベルの定量的評価に向けて2023
- Author(s)
  安藤颯、切原優太、武川和人、伊藤剛、長﨑裕加、西野耕平、小迫英尊、篠原康雄
- Organizer
  日本生化学会第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] ボンクレキン酸がミトコンドリアのADP/ATP輸送体を阻害する際に重要となる部分構造2023
- Author(s)
  武川和人、伊藤剛、長﨑裕加、新藤充、篠原康雄
- Organizer
  日本生化学会第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] 完全長のパルミトイルカルニチントランスフェラーゼ2は大腸菌に発現させると不溶性画分に選択的に濃縮されるが触媒活性を保持している2023
- Author(s)
  秋枝紀凜、武川和人、伊藤剛、長山岳、山崎尚志、長﨑裕加、西野耕平、小迫英尊、篠原康雄
- Organizer
  日本生化学会第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] ボンクレキン酸誘導体 KH-17はミトコンドリアの ADP/ATP輸送体を膜の外側からも弱く阻害する2022
- Author(s)
  武川和人、伊藤剛、山崎尚志、新藤充、篠原康雄
- Organizer
  日本生化学会第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K14838
[Presentation] 酵母発現系を用いたマラリア原虫リンゴ酸－キノン酸化還元酵素の機能研究2022
- Author(s)
  伊藤剛、梶田彩、藤井みのり、篠原康雄
- Organizer
  日本生体エネルギー研究会第48回討論会
- Data Source
  KAKENHI-PROJECT-22K14838

Ito Takeshi 伊藤 剛

伊藤 剛 イトウ タケシ

Research Projects

Research Products

Expression of malaria parasite mitochondrial protein in yeast and design of novel antimalarial compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Unique Behavior of Bacterially Expressed Rat Carnitine Palmitoyltransferase 2 and Its Catalytic Activity2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Insights into the Mechanism of Catalytic Activity of Plasmodium Parasite Malate-Quinone Oxidoreductase2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KH-17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bacteroides fragilis Maintains Concurrent Capability for Anaerobic and Nanaerobic Respiration2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] マラリア原虫リンゴ酸－キノン酸化還元酵素は酵母ミトコンドリアで機能発現する2023

Author(s)

Organizer

Data Source

[Presentation] 褐色脂肪組織を特徴づけるタンパク質の発現レベルの定量的評価に向けて2023

Author(s)

Organizer

Data Source

[Presentation] ボンクレキン酸がミトコンドリアのADP/ATP輸送体を阻害する際に重要となる部分構造2023

Author(s)

Organizer

Data Source

[Presentation] 完全長のパルミトイルカルニチントランスフェラーゼ2は大腸菌に発現させると不溶性画分に選択的に濃縮されるが触媒活性を保持している2023

Author(s)

Organizer

Data Source

[Presentation] ボンクレキン酸誘導体 KH-17はミトコンドリアの ADP/ATP輸送体を膜の外側からも弱く阻害する2022

Author(s)

Organizer

Data Source

[Presentation] 酵母発現系を用いたマラリア原虫リンゴ酸－キノン酸化還元酵素の機能研究2022

Author(s)

Organizer

Data Source

Ito Takeshi 伊藤剛

伊藤剛イトウタケシ