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YAMAGUCHI Osamu  山口 脩

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山口 脩  ヤマグチ オサム

山口 修  ヤマグチ オサム

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Researcher Number 60006814
Other IDs
External Links
Affiliation (Current) 2025: 日本大学, 工学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2016: 日本大学, 工学部, 教授
2008 – 2010: Fukushima Medical University, 医学部, 教授
2003: Fukushima Medical University Schoolof Medicine, Department of Urology, Professor and Chairman, 医学部・泌尿器科, 教授
2001 – 2003: 福島県立医科大学, 医学部, 教授
2000: 福島県立医科大学, 医学部・泌尿器科, 教授 … More
1997: Fukushima Medical University, School of Medicine Dept.of Urology, Professor, 医学部・泌尿器科, 教授
1996: 福島県立医科大学, 医学部, 教授
1995: 福島県立医科大学, 医学部・泌尿器科, 助教授
1992: 福島県立医科大学, 医学部・泌尿器科, 講師
1990 – 1992: 福島県立医科大学, 泌尿器科, 講師
1986: 福島医大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Urology / Urology
Except Principal Investigator
Urology
Keywords
Principal Investigator
cAMP / GABA / DSD / 収縮蛋白 / BKca channel / urge incontinence / overactive bladder / gene mutatation / β_3-adrenoceptor / β_3-アドレナリン受容体 … More / β3アドレナリン受容体 / 尿失禁 / BKcaチャネル / 切迫性尿失禁 / 過活動膀胱 / 遺伝子変異 / β_3アドレナリン受容体 / metastasis / invasion / cell metility / contractile protein / calcium ion / bradykinin / bladder tumor / ブラディキニン受容体 / 転移 / 浸潤 / 細胞運動 / カルシウムイオン / ブラディキニン / 膀胱癌 / micropump / intrathecal administration / bacrofen / enkephalin / ナロキソン / 脊髄内投与 / バクロフエン / 慢性脊髄損傷 / ミニポンプ / 骨髄内持続注入 / バクロフェン / エンケファリン / 拡張尿管 / 閉塞腎 / ミオシン / アクチン / 尿流動態検査医 / 増殖因子 / 閉塞モデル / 尿流動態検査 / 前立腺肥大症 … More
Except Principal Investigator
動脈硬化 / 膀胱過活動 / 膀胱低活動 / 膀胱虚血 / 低活動膀胱 / 精巣硬度 / 造精機能評価 / センサー / 硬度 / 精巣 Less
  • Research Projects

    (7 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (14 People)
  •  The development of a rat model of bladder underactivity induced by chronic bladder ischemia

    • Principal Investigator
      NOMIYA Masanori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      National Center for Geriatrics and Gerontology
      Nihon University
  •  触覚センサーを使用した精巣硬度定量による新しいヒト造精機能評価法の開発

    • Principal Investigator
      菅藤 哲
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      International University of Health and Welfare
  •  New Model of BPH with Slowly Advancing Obstruction to Investigate Pathophysiology and Mechanism of Obstructed BladderPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Osamu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Fukushima Medical University
  •  Urinary Incontinence and Mutation of β_3 Adrenoceptor GenePrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Osamu
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Fukushima Medical University
  •  Tumor Cell Invasion or Metastasis Related to Calcium Sensitivity of Intracellular Locomotive Apparatus in Bladder CancerPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Osamu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Fukushima Medical University, School of Medicine
  •  Administration of Drugs Using Implantable Micropump.Principal Investigator

    • Principal Investigator
      YAMAGUCHI Osamu
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Fukushima Medical College
  •  収縮蛋白を利用した閉塞性腎疾患および拡張尿管に対する診断法の開発Principal Investigator

    • Principal Investigator
      山口 脩
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Fukushima Medical University

All 2017 2016 2015 2014 2003 2002 Other

All Journal Article Presentation Book

  • [Book] Urology Today2014

    • Author(s)
      野宮正範、山口脩
    • Total Pages
      59
    • Publisher
      リッチヒルメディカル
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Journal Article] Silodosin, an α1A-Adrenoceptor Antagonist, May Ameliorate Ischemia-Induced Bladder Denervation and Detrusor Dysfunction by Improving Bladder Blood Flow.2016

    • Author(s)
      Goi Y, Tomiyama Y, Maruyama I, Tatemichi S, Maruyama K, Kobayashi M, Nomiya M, Yamaguchi O.
    • Journal Title

      Pharmacology

      Volume: 97(3-4) Pages: 161-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Journal Article] Chronic Pelvic Ischemia: Contribution to the Pathogenesis of Lower Urinary Tract Symptoms (LUTS): A New Target for Pharmacological Treatment?2015

    • Author(s)
      Andersson KE, Nomiya M, Yamaguchi O.
    • Journal Title

      Low Urin Tract Symptoms

      Volume: 1 Issue: 3 Pages: 1-8

    • DOI

      10.1016/j.juro.2015.10.117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Journal Article] Chronic bladder ischemia and oxidative stress: new pharmacotherapeutic targets for lower urinary tract symptoms.2015

    • Author(s)
      Nomiya M, Andersson KE, Yamaguchi O.
    • Journal Title

      Int J Urol

      Volume: 22(1) Issue: 1 Pages: 40-6

    • DOI

      10.1111/iju.12652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adorenoceptor subtypes and their functional roles in human normnal and obstructed bladders2003

    • Author(s)
      Nomiya M, Yamaguchi O
    • Journal Title

      THE JOURNAL OF UROLOGY 170

      Pages: 694-653

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders2003

    • Author(s)
      Nomiya M, Yamaguchi O
    • Journal Title

      THE JOURNAL OF UROLOGY 170

      Pages: 649-653

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] A quantitative analysis of α_1 and β-adorenoceptor subtypes mRNAs and their functional roles in human normal and obstructed bladders2002

    • Author(s)
      Nomiya M, Shishido K, Uchida H, Yamaguchi O
    • Journal Title

      NEUROUROLOGY AND URODYNAMICS 21

      Pages: 299-300

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] β_3-Adrenoceptors in human detrusor muscle2002

    • Author(s)
      Yamaguchi Osamu
    • Journal Title

      UROLOGY 59

      Pages: 25-29

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] β_3-adorenoceptors in human detrusor muscle2002

    • Author(s)
      Yamaguchi Osamu
    • Journal Title

      UROLOGY 59

      Pages: 25-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] A quantitative analysis of α_1 - and β-adorenoceptor subtypes mRNAs and their functional roles in human normal and obstructed bladders2002

    • Author(s)
      Nomiya M, Shishido K, Uchida H, Yamaguchi O
    • Journal Title

      NEUROUROLOGY AND URODYNAMICS 21(4)

      Pages: 299-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adrenoceptors.

    • Author(s)
      Uchida H, Shishido K, Nomiya M, Yamaguchi O
    • Journal Title

      Eur J pharmacol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Journal Article] Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adorenoceptors

    • Author(s)
      Uchida H, Shishido K, Nomiya M, Yamaguchi O
    • Journal Title

      Eur J pharmacol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470335
  • [Presentation] 慢性膀胱虚血ラットモデルにおける タダラフィルの膀胱微小血管内皮保護作用2017

    • Author(s)
      野宮正範 永田卓士 澤田智史  西井久枝 山口 脩 吉田正貴
    • Organizer
      第105回日本泌尿器科学会総会
    • Place of Presentation
      鹿児島市
    • Year and Date
      2017-04-21
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Presentation] 「低活動膀胱の診断と治療標的」 膀胱虚血の重症化と長期化による低活動膀胱への進行 -慢性骨盤虚血動物モデルでの検討-2016

    • Author(s)
      野宮正範、山口 脩、吉田正貴
    • Organizer
      第23回日本排尿機能学会
    • Place of Presentation
      東京
    • Year and Date
      2016-12-06
    • Data Source
      KAKENHI-PROJECT-26462454
  • [Presentation] 慢性膀胱虚血ラットモデルにおける虚血の重症化と長期化に関する検討―膀胱過活動から膀胱低活動への進行―2016

    • Author(s)
      野宮正範、今井佑樹、吉田正貴、山口 脩
    • Organizer
      第104回日本泌尿器科学会総会
    • Place of Presentation
      仙台市
    • Year and Date
      2016-04-25
    • Data Source
      KAKENHI-PROJECT-26462454
  • 1.  AIKAWA Ken (80295419)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KUSHIDA Nobuhiro (30381396)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  YOKOTA Takashi (20240939)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SHISHIDO Keiichi (30285035)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIRAIWA Manabu (40554168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NOMIYA Masanori (00398348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 7.  FUKAYA Yasuo (20192304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIMURA Yasukuni (50220744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HASHIMOTO Tasturu (70305374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  菅藤 哲 (40396487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  尾股 定夫 (90060186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  片寄 功一 (50161071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  胡口 正秀 (10170226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NANRI Masato
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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