YAMAGUCHI Osamu 山口脩

… Alternative Names

山口脩ヤマグチオサム

山口修ヤマグチオサム

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Researcher Number	60006814
Other IDs
External Links
Affiliation (Current)	2025: 日本大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2016: 日本大学, 工学部, 教授 2008 – 2010: Fukushima Medical University, 医学部, 教授 2003: Fukushima Medical University Schoolof Medicine, Department of Urology, Professor and Chairman, 医学部・泌尿器科, 教授 2001 – 2003: 福島県立医科大学, 医学部, 教授 2000: 福島県立医科大学, 医学部・泌尿器科, 教授 … More 1997: Fukushima Medical University, School of Medicine Dept.of Urology, Professor, 医学部・泌尿器科, 教授 1996: 福島県立医科大学, 医学部, 教授 1995: 福島県立医科大学, 医学部・泌尿器科, 助教授 1992: 福島県立医科大学, 医学部・泌尿器科, 講師 1990 – 1992: 福島県立医科大学, 泌尿器科, 講師 1986: 福島医大, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Urology / Urology Except Principal Investigator Urology
Keywords	Principal Investigator cAMP / GABA / DSD / 収縮蛋白 / BKca channel / urge incontinence / overactive bladder / gene mutatation / β_3-adrenoceptor / β_3-アドレナリン受容体 … More / β3アドレナリン受容体 / 尿失禁 / BKcaチャネル / 切迫性尿失禁 / 過活動膀胱 / 遺伝子変異 / β_3アドレナリン受容体 / metastasis / invasion / cell metility / contractile protein / calcium ion / bradykinin / bladder tumor / ブラディキニン受容体 / 転移 / 浸潤 / 細胞運動 / カルシウムイオン / ブラディキニン / 膀胱癌 / micropump / intrathecal administration / bacrofen / enkephalin / ナロキソン / 脊髄内投与 / バクロフエン / 慢性脊髄損傷 / ミニポンプ / 骨髄内持続注入 / バクロフェン / エンケファリン / 拡張尿管 / 閉塞腎 / ミオシン / アクチン / 尿流動態検査医 / 増殖因子 / 閉塞モデル / 尿流動態検査 / 前立腺肥大症 … More Except Principal Investigator 動脈硬化 / 膀胱過活動 / 膀胱低活動 / 膀胱虚血 / 低活動膀胱 / 精巣硬度 / 造精機能評価 / センサー / 硬度 / 精巣 Less

The development of a rat model of bladder underactivity induced by chronic bladder ischemia
- Principal Investigator
  
  NOMIYA Masanori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  National Center for Geriatrics and Gerontology
  Nihon University
触覚センサーを使用した精巣硬度定量による新しいヒト造精機能評価法の開発
- Principal Investigator
  
  菅藤哲
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  International University of Health and Welfare
New Model of BPH with Slowly Advancing Obstruction to Investigate Pathophysiology and Mechanism of Obstructed BladderPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Osamu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Urinary Incontinence and Mutation of β_3 Adrenoceptor GenePrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Osamu
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Tumor Cell Invasion or Metastasis Related to Calcium Sensitivity of Intracellular Locomotive Apparatus in Bladder CancerPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Osamu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University, School of Medicine
Administration of Drugs Using Implantable Micropump.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Osamu
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical College
収縮蛋白を利用した閉塞性腎疾患および拡張尿管に対する診断法の開発Principal Investigator
- Principal Investigator
  
  山口脩
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University

All 2017 2016 2015 2014 2003 2002 Other

All Journal Article Presentation Book

[Book] Urology　Today2014
- Author(s)
  野宮正範、山口脩
- Total Pages
  59
- Publisher
  リッチヒルメディカル
- Data Source
  KAKENHI-PROJECT-26462454
[Journal Article] Silodosin, an α1A-Adrenoceptor Antagonist, May Ameliorate Ischemia-Induced Bladder Denervation and Detrusor Dysfunction by Improving Bladder Blood Flow.2016
- Author(s)
  Goi Y, Tomiyama Y, Maruyama I, Tatemichi S, Maruyama K, Kobayashi M, Nomiya M, Yamaguchi O.
- Journal Title
  
  Pharmacology
  
  Volume: 97(3-4) Pages: 161-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462454
[Journal Article] Chronic Pelvic Ischemia: Contribution to the Pathogenesis of Lower Urinary Tract Symptoms (LUTS): A New Target for Pharmacological Treatment?2015
- Author(s)
  Andersson KE, Nomiya M, Yamaguchi O.
- Journal Title
  
  Low Urin Tract Symptoms
  
  Volume: 1 Issue: 3 Pages: 1-8
- DOI
  10.1016/j.juro.2015.10.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462454
[Journal Article] Chronic bladder ischemia and oxidative stress: new pharmacotherapeutic targets for lower urinary tract symptoms.2015
- Author(s)
  Nomiya M, Andersson KE, Yamaguchi O.
- Journal Title
  
  Int J Urol
  
  Volume: 22(1) Issue: 1 Pages: 40-6
- DOI
  10.1111/iju.12652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462454
[Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adorenoceptor subtypes and their functional roles in human normnal and obstructed bladders2003
- Author(s)
  Nomiya M, Yamaguchi O
- Journal Title
  
  THE JOURNAL OF UROLOGY 170
  
  Pages: 694-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders2003
- Author(s)
  Nomiya M, Yamaguchi O
- Journal Title
  
  THE JOURNAL OF UROLOGY 170
  
  Pages: 649-653
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] A quantitative analysis of α_1 and β-adorenoceptor subtypes mRNAs and their functional roles in human normal and obstructed bladders2002
- Author(s)
  Nomiya M, Shishido K, Uchida H, Yamaguchi O
- Journal Title
  
  NEUROUROLOGY AND URODYNAMICS 21
  
  Pages: 299-300
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] β_3-Adrenoceptors in human detrusor muscle2002
- Author(s)
  Yamaguchi Osamu
- Journal Title
  
  UROLOGY 59
  
  Pages: 25-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] β_3-adorenoceptors in human detrusor muscle2002
- Author(s)
  Yamaguchi Osamu
- Journal Title
  
  UROLOGY 59
  
  Pages: 25-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] A quantitative analysis of α_1 - and β-adorenoceptor subtypes mRNAs and their functional roles in human normal and obstructed bladders2002
- Author(s)
  Nomiya M, Shishido K, Uchida H, Yamaguchi O
- Journal Title
  
  NEUROUROLOGY AND URODYNAMICS 21(4)
  
  Pages: 299-300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adrenoceptors.
- Author(s)
  Uchida H, Shishido K, Nomiya M, Yamaguchi O
- Journal Title
  
  Eur J pharmacol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Journal Article] Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adorenoceptors
- Author(s)
  Uchida H, Shishido K, Nomiya M, Yamaguchi O
- Journal Title
  
  Eur J pharmacol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470335
[Presentation] 慢性膀胱虚血ラットモデルにおけるタダラフィルの膀胱微小血管内皮保護作用2017
- Author(s)
  野宮正範　永田卓士　澤田智史　西井久枝　山口　脩　吉田正貴
- Organizer
  第105回日本泌尿器科学会総会
- Place of Presentation
  鹿児島市
- Year and Date
  2017-04-21
- Data Source
  KAKENHI-PROJECT-26462454
[Presentation] 「低活動膀胱の診断と治療標的」膀胱虚血の重症化と長期化による低活動膀胱への進行 -慢性骨盤虚血動物モデルでの検討-2016
- Author(s)
  野宮正範、山口　脩、吉田正貴
- Organizer
  第23回日本排尿機能学会
- Place of Presentation
  東京
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-26462454
[Presentation] 慢性膀胱虚血ラットモデルにおける虚血の重症化と長期化に関する検討―膀胱過活動から膀胱低活動への進行―2016
- Author(s)
  野宮正範、今井佑樹、吉田正貴、山口　脩
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  仙台市
- Year and Date
  2016-04-25
- Data Source
  KAKENHI-PROJECT-26462454

1. AIKAWA Ken (80295419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KUSHIDA Nobuhiro (30381396)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YOKOTA Takashi (20240939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHISHIDO Keiichi (30285035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SHIRAIWA Manabu (40554168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NOMIYA Masanori (00398348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. FUKAYA Yasuo (20192304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIMURA Yasukuni (50220744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HASHIMOTO Tasturu (70305374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 菅藤哲 (40396487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 尾股定夫 (90060186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 片寄功一 (50161071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 胡口正秀 (10170226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NANRI Masato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGUCHI Osamu 山口 脩

山口 脩 ヤマグチ オサム

山口 修 ヤマグチ オサム

Research Projects

Research Products

Co-Researchers

The development of a rat model of bladder underactivity induced by chronic bladder ischemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

触覚センサーを使用した精巣硬度定量による新しいヒト造精機能評価法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Model of BPH with Slowly Advancing Obstruction to Investigate Pathophysiology and Mechanism of Obstructed BladderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Urinary Incontinence and Mutation of β_3 Adrenoceptor GenePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tumor Cell Invasion or Metastasis Related to Calcium Sensitivity of Intracellular Locomotive Apparatus in Bladder CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Administration of Drugs Using Implantable Micropump.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

収縮蛋白を利用した閉塞性腎疾患および拡張尿管に対する診断法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Urology Today2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Silodosin, an α1A-Adrenoceptor Antagonist, May Ameliorate Ischemia-Induced Bladder Denervation and Detrusor Dysfunction by Improving Bladder Blood Flow.2016

Author(s)

Journal Title

Data Source

[Journal Article] Chronic Pelvic Ischemia: Contribution to the Pathogenesis of Lower Urinary Tract Symptoms (LUTS): A New Target for Pharmacological Treatment?2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic bladder ischemia and oxidative stress: new pharmacotherapeutic targets for lower urinary tract symptoms.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adorenoceptor subtypes and their functional roles in human normnal and obstructed bladders2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] A quantitative analysis of mRNA expression of α_1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] A quantitative analysis of α_1 and β-adorenoceptor subtypes mRNAs and their functional roles in human normal and obstructed bladders2002

Author(s)

Journal Title

YAMAGUCHI Osamu 山口脩

山口脩ヤマグチオサム

山口修ヤマグチオサム

[Book] Urology　Today2014

[Presentation] 慢性膀胱虚血ラットモデルにおけるタダラフィルの膀胱微小血管内皮保護作用2017

[Presentation] 「低活動膀胱の診断と治療標的」膀胱虚血の重症化と長期化による低活動膀胱への進行 -慢性骨盤虚血動物モデルでの検討-2016