MAJIMA Yuichi 間島雄一

Researcher Number	60024791
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Affiliation (based on the past Project Information) *help	2007: Mie University, Graduate school of Medicine, Professor 2006: 三重大学, 大学院医学系研究科, 教授 2005: Mie University, Hospital, Professor, 大学院・医学系研究科, 教授 1999 – 2004: 三重大学, 医学部, 教授 1998: 三重大学, 医学部, 助教授 … More 1995 – 1997: 三重大学, 医学部・附属病院, 講師 1990: Mie University Hospital, Assistant Professor, 医学部・附属病院, 講師 1987 – 1990: 三重大学, 医学部附属病院, 講師 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Otorhinolaryngology
Keywords	Principal Investigator mucus / 気道液 / 慢性副鼻腔炎 / animal model / chronic sinusitis / 動物モデル / extracellular matrix / submucosal gland / remodeling / nasal polyposis … More / allergic rhinitis / 気道分泌 / ムチン遺伝子 / 副鼻腔 / 鼻 / 細胞外マトリックス / 粘液 / 粘膜下腺 / リモデリング / 鼻茸 / アレルギー性鼻炎 / growth factor / hyperplasia / differentiation / proliferation / gland / 粘性・弾性 / 粘性,弾性 / 粘性、弾性 / 粘液産生モデル / 腺の増殖 / 腺の分化 / 増殖因子 / 過形成 / 分化 / 増殖 / 腺細胞 / neutrophil / 3-D culture / goblet cell / mucous cell / serous cell / mucus production / airway / 粘液腔 / 気通液 / レオロジー / 奬液腺 / 奨液腺 / 粘膜産生 / 好中球 / 3D培養 / 杯細胞 / 漿液腺 / 粘液腺 / 粘液産生 / 気道 / 薬物療法 / 弾性率 / 粘性率 / 粘液繊毛機能 / 弾性 / 粘性 / 中耳腔貯留液 / 滲出性中耳炎 / Lーシステインエチル塩酸塩 / 粘液融解剤 … More Except Principal Investigator 鼻粘膜 / 鼻アレルギー / アレルギー性鼻炎 / nasal mucosa / allergic rhinitis / histamine / ヒスタミン / ロイコトリエン / mucin / ムチン / 細胞外マトリックス / Nasal allergy / 糖蛋白 / 滲出性中耳炎 / ヒスタミン遊離率 / 免疫療法 / ヒスタミン遊離試験 / スギ花粉症 / Experimental model of otitis media effusion / Mucociliary function / Mucous glycoprotein / Dynamic viscosity / Elastic modulus / Middle ear effusion / Otitis media with effusion / 酵素 / 組織化学 / 粘性 / スピナビリティー / 弾性 / 中耳貯留液 / リゾゾマールプロテアーゼ / 滲出性中耳炎モデル / 粘液繊毛機能 / 粘液糖蛋白 / 弾性率 / 粘性率 / 中耳腔貯留液 / remodeling / steroid / leukotriene / extracellular matrix / 卵白アルブミン / 上皮細胞 / 抗原刺激 / 杯細胞 / モルモット / リモデリング / ステロイド / histamine release test / basophil / immunotherapy / 好塩基 / 好塩基球 / mucus secretion / synapses / submucosal glands / histamine H3 receptors / RT-PCR / 粘膜下腺 / 粘液分泌 / シナプス / 粘膜下線 / H3受容体 / transepithelial resistance / leukotrienes / thrombin / tight junction / permeability / epithelium / horeseradish peroxidase / 密着結合蛋白 / 膜抵抗 / トロンビン / 密着結合 / 透過性 / 気道上皮細胞 / neutrophil elastase / lipopolysaccharide / gene expression / sialyltransferase / fucosyltransferase / 粘液 / mRNA / DNA / 上気道 / 糖転移遺伝子 / 好中球エラスターゼ / リポポリサッカライド / 遺伝子発現 / 糖添加酵素 / Matrix metalloproteinase / Extracellular matrix / Paranasal sinusitis / Nasal polyp / マトリックスメタロプロテアーゼ / 鼻副鼻腔炎 / 鼻茸 / Mucus secreting cell / protease / otitis media with effusion / Chronic sinusitis / Respiratory mucus / Elasticity, viscosity / Ion transport / 蛋白分解酵素 / 浸出性中耳炎 / 動的粘性率、動的弾性率 / 定量的細胞診 / 分泌細胞 / プロテア-ゼ / 鼻アレルギ- / 慢性副鼻腔炎 / 気道液 / 弾性率,粘性率 / 膜のイオン輸送 / 減感作療法 / ヒスタミン遊離 / 舌下免疫療法 Less

A study of clinical efficacy and biomarkers of newly developed sublingual immunotherapy for Japanese cedar pollinosis
- Principal Investigator
  
  YUTA Astushi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Characteristics and control of the upper airway remodeling
- Principal Investigator
  
  TAKEUCHI Kazuhiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Remodeling of the nose and the paranasal sinuses under diseased conditionsPrincipal Investigator
- Principal Investigator
  
  MAJIMA Yuichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
A study of new mechanisms by basophils on immunotherapy for allergic rhinitis
- Principal Investigator
  
  YUTA Atsushi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Localization and function of histamine H3 receptors in the nasal mucosa
- Principal Investigator
  
  TAKEUCHI Kazuhiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Molecular Mechanism of Barrier Function Changes of Epithelial Tight Junction in Allergic Rhinitis
- Principal Investigator
  
  TAKEUCHI Kazuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
MECHANISMS OF PROLIFERATION AND DIFFERENTIATION OF AIRWAY GLANDSPrincipal Investigator
- Principal Investigator
  
  MAJIMA Yuichi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Analysis of glycosyltransferases mRNA expression in the upper airway inflammatory diseases
- Principal Investigator
  
  SAKAKURA Yasuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
The study of mucus hypersecretion in respiratory glands.Principal Investigator
- Principal Investigator
  
  MAJIMA Yuichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Degradation system of extracellular matrix components in nasal polyp formation
- Principal Investigator
  
  HARADA Teruhiko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
滲出性中耳炎中耳腔貯留液のレオロジ-的性質に及ぼす経口薬剤の効果Principal Investigator
- Principal Investigator
  
  間島雄一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Physicochemical Properties of Upper Respiratory Mucus
- Principal Investigator
  
  SAKAKURA Yasuo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University School of Medicine
慢性副鼻腔炎鼻汁のレオロジー的性質に及ぼす薬物の効果Principal Investigator
- Principal Investigator
  
  間島雄一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University
Pathophysiology of otitis media with effusion
- Principal Investigator
  
  SAKAKURA Yasuo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Mie University

All 2009 2007 2006 2005 2003

All Journal Article

[Journal Article] スギ花粉症に対する免疫療法のヒノキ科花粉症への効果2009
- Author(s)
  湯田厚司, 服部玲子, 坂井田寛, 三品朋子, 鈴木あゆ美, 竹内万彦, 臼井智子, 間島雄一
- Journal Title
  
  日鼻誌 46
  
  Pages: 109-113
- NAID
  10019726895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591865
[Journal Article] 当科におけるスギ花粉症に対する舌下免疫療法の現状と2年間の治療成績2009
- Author(s)
  湯田厚司, 大久保公裕, 服部玲子, 押正徳, 清水優, 間島雄一
- Journal Title
  
  耳鼻免疫アレルギー 26(4)
  
  Pages: 285-289
- NAID
  10024836350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591865
[Journal Article] 三重県におけるスギ・ヒノキ科花粉の2008年飛散結果と2009 年飛散予想2009
- Author(s)
  湯田厚司, 間島雄一, 他
- Journal Title
  
  東海花粉症 20
  
  Pages: 26-32
- Data Source
  KAKENHI-PROJECT-18591865
[Journal Article] スギ花粉症に対する抗原特異的免疫療法の花粉飛散総数による医療経済効果-医療費による直接経費からの検討-2007
- Author(s)
  湯田厚司, 宮本由起子, 服部玲子, 荻原仁美, 竹内万彦, 間島雄一
- Journal Title
  
  アレルギー 56
  
  Pages: 1366-1371
- NAID
  110006474345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591865
[Journal Article] 三重県におけるスギヒノキ科花粉飛散結果と2006年飛散予想2006
- Author(s)
  湯田厚司, 間島雄一他
- Journal Title
  
  東海花粉症誌 17
  
  Pages: 28-33
- Data Source
  KAKENHI-PROJECT-18591865
[Journal Article] Remodeling in chronic sinusitis and nasal polyps.2005
- Author(s)
  Takeuchi K, Majima Y
- Journal Title
  
  Allergology International 54
  
  Pages: 39-43
- NAID
  10014468592
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390516
[Journal Article] Human nasal gland cells cultured in a three-dimensional collagen gel matrix.2003
- Author(s)
  Majima Y, et al.
- Journal Title
  
  Proceeding of Airway Secretion Research 5
  
  Pages: 27-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390516
[Journal Article] Remodeling of the nose and the paranasal sinuses.2003
- Author(s)
  Majima Y, et al.
- Journal Title
  
  JJIAO 21
  
  Pages: 7-14
- NAID
  10012081165
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390516

1. SAKAKURA Yasuo (40024723)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. TAKEUCHI Kazuhiko (50206942)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. YUTA Astushi (80293778)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. SHIMIZU Takeshi (00206202)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HIRATA Keisuke (70199066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HAMAGUCHI Yukiyoshi (80172964)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HARADA Teruhiko (20183569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KISHIOKA Chikako (10314113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SAIDA Satoshi (60205630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UKAI Kotaro (80024735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ISHINAGA Hajime (50335121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAKAIDA Hiroshi (30378426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MAJIMA Yuichi 間島 雄一

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Remodeling of the nose and the paranasal sinuses under diseased conditionsPrincipal Investigator

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MECHANISMS OF PROLIFERATION AND DIFFERENTIATION OF AIRWAY GLANDSPrincipal Investigator

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The study of mucus hypersecretion in respiratory glands.Principal Investigator

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滲出性中耳炎中耳腔貯留液のレオロジ-的性質に及ぼす経口薬剤の効果Principal Investigator

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慢性副鼻腔炎鼻汁のレオロジー的性質に及ぼす薬物の効果Principal Investigator

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[Journal Article] スギ花粉症に対する免疫療法のヒノキ科花粉症への効果2009

MAJIMA Yuichi 間島雄一