NODE Manabu 野出學

… Alternative Names

野出学ノデマナブ

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Researcher Number	60027076
Other IDs
Affiliation (based on the past Project Information) *help	1992 – 2008: 京都薬科大学, 薬学部, 教授 1990: 京都薬科大学, 薬学部, 教授 1986 – 1989: Institute for Chemical Research, Kyoto University, 化学研究所, 助教授
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy / Biological Sciences Except Principal Investigator Chemical pharmacy / Biological pharmacy / Chemical pharmacy
Keywords	Principal Investigator dichroanone / dichroanal B / Michael付加 / pentafluorobenzoic acid / α,β-不飽和ケトン / 不斉全合成 / メルカプトアルコール / inhibitory activity against aromatase / taiwaniaauinone H / standishinal analogs … More / dynamic kinetic resolution / atropisomer / asymmetric Heck reaction / 構造-活性相関 / standishinal 類縁体 / アトロブ異性 / アロマターゼ阻害活性 / taiwaniaquinone H / standishinal類縁体 / 動的速度論分割 / アトロプ異性 / 不斉Heck反応 / Amaryllidaceae alkaloids / phenyliodine(III) bis(trifluoroacetate) / oxidative phenol coupling / norbelladine type compound / remote asymmetric induction / (-)-galanthamine / phenyliodine(iii)bis(trifluoroacetate) / 遠隔位不斉誘導 / ヒガンバナ科植物 / コリンエステラーゼ阻害活性 / アルツハイマー病治療薬 / 酸化的フェノールカップリング / アルツハイマー治療薬 / ガランタミン / ヒガンバナ科アルカロイド / 超原子価ヨー素 / フェノールカップリング / ノルベラジン型化合物 / 遠隔不斉誘導 / (-)-ガランタミン / odorless sulfide / odorless thiol / three contiguous chiral centers / dimethylchloroaluminum / MPV reduction / Michael addition / mercapto alcohol / 不斉MPV反応 / 不斉ミカエル付加 / カプトプリル / Raney-Nickel / 不斉プロトン化 / α, β-不飽和アミド / α, β-不飽和エステル / 3連続不斉炭素構築 / conjugate addition-protonation-MPV還元 / 3,4-ジヒドロ-2H-チオピラン / [4+2]cycloaddition-elimination / 1,3-オキサチアン / 光学活性メルカプトアルコール / γ-ブチロラクトン / キラルアルコール / メルカプト基 / 無臭スルフィド / 無臭チオール / 3連続不斉炭素 / ジメチルクロロアルミニウム / MPV還元 / Michase付加 / Optically Active Alcohols / Asymmetric Bifunctional Group Exchange Reaction / Asymmetric Protonation / Dynamic Kinetic Resolution / Anymmetric 1,7-Hydride Shift / Asymmetric Tandem Michael-MPV Reaction / Chinal Mercapto Alcohols / α,β-Unsaturated Compounds / 1,7-水素転位 / 光学活性アリルアルコール / 不斉Michael付加反応 / 光学活性γ-メルカプトアルコール / 不斉TandemMichael-MPV反応 / 光学活性アルコール / 不斉官能基交換型反応 / 不斉プロトン化反応 / 動的速度論的分割 / 不斉1,7-水素転位 / 不斉Tandem Michael-MPV反応 / キラルメルカプトアルコール / α,β-不飽和カルボニル化合物 / NF-1147 / 選択的阻害 / II型トポイソメラーゼ / ヒト乳癌MDA-MB-231 / 環式アミノアルコール / シクロブタン骨格 / 新規ピリミジン系抗癌剤 / Mycestericien E,F / 免疫抑制物質 / オキサゾリン誘導体 / 光学分割法 / リパーゼ / 脱アルコキシカルボニル化反応 / パン酵母 / (-)-Eptazocine / (-)-Aphanorphine / Danishefskyジエン / エキソ選択的Diels-Alder反応 / 光学活性ニトロオレフィンラクトン / 不斉ニトロエナミン / 不斉ニトロオレフィン化反応 / optically active sec-alcohol / intramoleculat MPV reduction / Lewis acid / chiral 3-mercaptoalcohol / dedithioacetalization / demonothioacetalization / silver salt-iodine / AgNO_2-I_2 / 脱モノチオアセタール化 / 置換反応 / β-ニトロビニルスルホキシド / β-ニトロビニルスルフィド / α-ニトロケトン / 光学活性環式ニトロオレフィン / 二量化体 / アルキルチオ基 / エポキシ / α,βー不飽和ケトン / リ-ド化合物 / 天然抗腫瘍活性化合物 / 抗癌活性化合物 / 複数の活性中心 … More Except Principal Investigator Rabdosia trichocarpa Hara / Nucleophile-Electrophile Interaction / retention of configuration / optically active alcohol / sulfoxide / thio ether / reductive desulfurization / hypophosphite / Raney nickel / Chiral Synthesis / Indole Alkaloid / Optical Resolution / Addition-Elimination / Protonation / Enantioselective Reaction / Asymmetric Synthesis / アスピドスペルミジン / インドールアルカロイド / ニトロオレフィン / キラル合成 / インド-ルアルカロイド / 光学分割 / 付加・脱離反応 / プロトン化 / エナンチオ選択的反応 / 不斉合成 / Trichorabdak B and C / Diterpenoid / mouse Serum cortichosterone / Rat / クロバナヒキオコシ / Corticosterone / ラット / 血液脳関門 / 15ーHydroxyKaurene / Trichorabdal C / Trichorabdal B / Iso lated Rat Adrenal Cells / Serum Corticosterone / Steroidogenic activity (Rat,Mouse) / Hydroxylated 15-oxo-Kaurene / 15-oxo-Kaurene / Nodosine / Longikaurine / TrichorabdalBおよびC / 延命草ジテルペノイド / radiosencitizer / diabetes / aldose reductase inhibitor / oridonin / nitroimidazole / nitrotriazole / nitrofurazane / thiazolidine-2-thione carboxylic acid / multifunctional anti-cancer agent / オリドニン / 2-ニトロイミダゾール / 3-ニトロトリアゾール / ニトロベンゾフラザン / ベンゾ〔C〕フェナンスリジンアルカロイド / アルドース還元酵素阻害 / チアゾリジン-2-チオンカルボン酸 / 多機能性抗癌剤 / Diels-Alder Reaction / Aliphatic Fluorocyanides / Stereoselective Protonation / Through Space n_F → π^* Interaction / X-Ray Crystallographic Analysis / Cyano group / Fluoro group / 立体配座固定 / Through space n_0→π^Interaction / van der Waals radii / 立体選択的アルキル化 / 立体選択的プロトン化 / Through Space n_0→σ^Interaction / Through Space n_0→π^Interaction / 脂肪族直鎖化合物 / Diels-Alder反応 / 脂肪族直鎖フルオロシアノ化合物 / 立体選択的プロトン化反応 / Through Space n_F→π^ Interaction / X-線構造解析 / シアノ基 / フッ素基 / alpha, beta-unsaturated ketone / α,β-unsaturated ketone / reductive desulfrization / α, β-unsaturated ketone / 殺細胞作用 / 抗癌作用 / 構造活性相関 / P388 / ジテルペン / シソ科 / 抗腫瘍化合物 / ο-ニトロベンジル基 / アグリコン / セラミド類似体 / N-アセチルグルコサミン転移酵素-V / チオグリコシド / CH_3CN試薬系 / CCl_4 / PPh_3 / TsOH / p-ドデシルフェニルスルホキシル基 / PPh_3/CCl_4/CH_3CN試薬系 / NIS/TsOH / p-ドデシルベンゼンチオール / 非還元末端からの糖鎖合成 / CH3CN試薬系 / CCl4 / PPh3 / TfOH / NIS / N-アセチルグルコサミン転移酵素V / 1-チオ-D-グルコサミニド / グリコシル化反応 / 無臭ベンゼンチオール / p-オクチルオキシベンゼンチオール / 光学活性α-ヒドロキシアルデヒド / 光学活性モノチオアセタール / Raney Nickel-Combination System / 還元的脱硫反応 / キラルメルカプトアルコール / 光学活性二級アルコール / 高選択的不斉還元反応 / 不斉Tandem Michael-MPV反応 / (-)-Eptazocine / (-)-Aphanorphine / Quaternary Carbon / (+)-1,1′-Binaphthol / (+)-Blastmycinone / Alkhlation / (S)-2-Methoxymethylpyrrolidine / Tetronic Acid Less

Development of Novel Glycosylation Reaction Using Odorless Benzenethiols
- Principal Investigator
  
  KAJIMOTO Tetsuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Suzuka University of Medical Science
Development of a Novel Asymmetric Heck Reaction based on Dynamic Kinetic Resolution and Its ApplicationPrincipal Investigator
- Principal Investigator
  
  NODE Manabu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Study on Effective Asymmetric Total Synthesis of Gallanthamine, a Drug for Alzheimer's disease.Principal Investigator
- Principal Investigator
  
  NODE Manabu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Studies on the construction of multi-contiguous asymmetric synthesis using mercapto alcohol as a chiral templatePrincipal Investigator
- Principal Investigator
  
  NODE Manabu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
新しい作用機序を有する新規ピリミジン系抗ガン剤の開発研究Principal Investigator
- Principal Investigator
  
  野出學
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Pharmaceutical University
Studies on the Through Space n_0 → π^* and n_0 → σ^* Interaction
- Principal Investigator
  
  NISHIDE Kiyoharu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Studies on the Development of Novel Asymmetric Multi-Functional MPV ReductionPrincipal Investigator
- Principal Investigator
  
  NODE Manabu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Exploitation of a New Method for the Reductive Desulfurization without Racemization of a Secondary Alcohol
- Principal Investigator
  
  NISHIDA Kiyoharu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
生体触媒による脱エステル化反応を用いる新規不斉合成の開発研究Principal Investigator
- Principal Investigator
  
  野出學
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
不斉ニトロオレフィン化反応の改良と新規不斉合成素子の開発研究Principal Investigator
- Principal Investigator
  
  野出學
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
官能基交換型新規不斉合成反応の開発研究
- Principal Investigator
  
  西出喜代治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
新しい脱モノチオアセタール化反応剤の開発とその不斉合成への応用Principal Investigator
- Principal Investigator
  
  野出學
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
beta位にヘテロ原子を有する不飽和エステル類のalpha及びgamma選択的不斉アルキル化反応の開発
- Principal Investigator
  
  NISHIDE Kiyoharu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
HSAB則に基づく新反応の開発;環式ニトロ化合物の不斉合成Principal Investigator
- Principal Investigator
  
  野出学
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
複数の活性中心を持つ抗癌医薬品の分子設計Principal Investigator
- Principal Investigator
  
  野出学
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Pharmaceutical University
Construction of Chiral Building Blocks through Enantioselective Protonation
- Principal Investigator
  
  FUJI Kaoru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
天然物を基盤とする新しい抗癌医薬品の開発(活性中心の複数化による抗癌作用増強化)
- Principal Investigator
  
  FUJI Kaoru
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
AN INVESRIGATION TO THE EFFECT OF DITERPENOID ON THE BLOOD BRAIN BARRIER
- Principal Investigator
  
  SAI MIDORI
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIV.
Design and Synthetic Development of New Multifunctional Anti-cancer Agents
- Principal Investigator
  
  NAGAO Yoshimitsu
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University

All 2011 2010 2009 2008 2007 2006 2004 2001

All Journal Article Presentation

[Journal Article] Synthesis and evaluation of a radioiodinated trisaccharide deriv-ative as a synthetic substrate for sensitive N-acetylglucosaminyl-transferase Vradiossay2011
- Author(s)
  T.Mukai, M.Hagimori, K.Ari-mistsu, T.Katoh, M.Ukon, Y.Magata, E.Miyoshi, N.Tanigu-chi, M.Node, T.Kajimoto, H.Saji
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Synthesis and Evaluation of a Radioiodinated Trisaccharide Derivative as a Synthetic Substrate for Sensitive N-Acetylglucosaminyltransferase V Radioassay2011
- Author(s)
  T.Mukai, M.Hagimori, K.Arimitsu, T.Katoh, M.Ukon, T.Kajimoto, H.Kimura, Y.Magata, E.Miyoshi, N.Taniguchi, M.Node, H.Saji
- Journal Title
  
  Bioorg.Med.Chem. (in press)
- NAID
  120003255723
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Total synthesis of (+)-negamycin and its 5-epi-derivatives2010
- Author(s)
  S.Nishiguchi, M.O.Sydnes, A.Taguchi, T.Regnier, T.Kajimoto, M.Node, Y.Yamazaki, F.Yakushiji, Y.Kiso, Y.Hayashi
- Journal Title
  
  Tetrahedron 66
  
  Pages: 314-320
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Development of Novel Asymmetric Reaction and Its Application to Synthesis of Natural Products2010
- Author(s)
  M.Node, T.Kajimoto, M.Ozeki
- Journal Title
  
  Heterocycles
  
  Volume: 81 Pages: 1061-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Glycosylation from the Non-reducing End Using a Combination of Thioglycoside and Glycosyl Sulfoxide as the Glycosyl Donor and the Acceptor2010
- Author(s)
  T.Kajimoto, K.Arimitsu, M.Ozeki, M.Node
- Journal Title
  
  Chem.Pharm.Bull. 58
  
  Pages: 758-764
- NAID
  130000255844
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Development of Novel Asymmetric Reaction and Its Application to Synthesis of Natural Products2010
- Author(s)
  M.Node, T.Kajimoto, M.Ozeki
- Journal Title
  
  Heterocycles 81
  
  Pages: 1061-1092
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Total synthesis of (+)-negamycin and its 5-epi-derivatives2010
- Author(s)
  S.Nishiguchi, M.O.Sydnes, A.Taguchi, T.Regnier, T.Kajimoto, M.Node, Y.Yamazaki, F.Yakushiji, Y.Kiso, Y.Hayashi
- Journal Title
  
  Tetrahedron
  
  Volume: 66 Pages: 314-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Inhibitors against Glycosidases as Medicines2009
- Author(s)
  T.Kajimoto, M.Node
- Journal Title
  
  Curr.Topics in Med.Chem. 9
  
  Pages: 13-33
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] The First Enantioselective Synthesis of Imino-deoxydigitoxose andProtected Imino-digitoxose by Using L-Threonine Aldolase-CatalyzedAldol Condensation2009
- Author(s)
  T. Nishiyama, T. Kajimoto, S. S. Mohile, N. Hayama, T. Ots-uda, M. Ozeki, M. Node
- Journal Title
  
  Tetrahedron : Asymmetry 20
  
  Pages: 230-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] The First Enantioselective Synthesis of Imino-deoxydigitoxose and Protected Imino-digitoxose by Using L-Threonine Aldolase-Catalyzed Aldol Condensation2009
- Author(s)
  T.Nishiyama, T.Kajimoto, S.S.Mohile, N.Hayama, T.Otsuda, M.Ozeki, M.Node
- Journal Title
  
  Tetrahedron : Asymmetry 20
  
  Pages: 230-234
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Synthesis of inhibitors of glycosyltransferases2009
- Author(s)
  T.Kajimoto, M.Node
- Journal Title
  
  Synthesis
  
  Pages: 3179-3210
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Efficient total synthesis of (+)-negamycin, a potential chemotherapeutic agent for genetic diseases2008
- Author(s)
  Y. Hayashi, T. Regnier, S. Ni-shiguchi, M. O. Sydnes, D. Ha-shimoto, J. Hasegawa, T. Katoh, T. Kajimoto, M. Shiozuka, R. Matsuda, M. Node, Y. Kiso
- Journal Title
  
  J. Chem. Soc., Chem. Commun 2008
  
  Pages: 2379-2381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Application of Odorless Thiols for Cleavage of 2- and 4-Nitrobenzenesulfonamide2008
- Author(s)
  M.Matoba, T.Kajimoto, M.Node
- Journal Title
  
  Synthetic Commun. 38
  
  Pages: 1194-1200
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Selective C-N bond oxidation : demethylation of N-methyl groups in N-arylmethyl-N- methyl-α-amino esters utilizing N-iodosuccinimide (NIS)2008
- Author(s)
  T. Katoh, T. Watanabe, M. Ni-shitani, M. Ozeki, T. Kajimoto, M. Node
- Journal Title
  
  Tetrahedron Lett. 49
  
  Pages: 598-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Selective C-N bond oxidation : demethylation of N-methyl groups in N-arylmethyl-N- methyl-α-amino esters utilizing N-iodosuccinimide (NIS)2008
- Author(s)
  T.Katoh, T.Watanabe, M.Nishitani, M.Ozeki, T.Kajimoto, M.Node
- Journal Title
  
  Tetrahedron Lett 49
  
  Pages: 598-600
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Application of Odorless Thiols for Cleavage of 2- and 4-Nitrobenzene-sulfonamide2008
- Author(s)
  M. Matoba, T. Kajimoto, M. Node
- Journal Title
  
  Synthetic Commun. 38
  
  Pages: 1194-1200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Transforming growth factor β receptor phosphorylation inhibitor is the-rapeutically promising for the dissemination of scirrhous gastric carci-noma2008
- Author(s)
  H. Kawajiri, M. Yashiro, O. Shinto, K. Nakamura, M. TendoS. Takemura, M. Node, Y. Ha-mashima, T. Kajimoto, K. Mi-yazono, K. Hirakawa
- Journal Title
  
  Clinical Cancer Res. 14
  
  Pages: 2850-2860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Asymmetric Michael Addition of a Recyclable Chiral Amine : Inversion of Stereoselectivity Caused by the Difference of Etherial Solvents2008
- Author(s)
  M. Node, D. Hashimoto, T. Ka-toh, S. Ochi, T. Watanabe, T. Kajimoto
- Journal Title
  
  Org. Lett. 10
  
  Pages: 2653-2656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590022
[Journal Article] Synthesis of DL-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase.2007
- Author(s)
  Takahiro Katoh, Taichi Akagi, Chie Noguchi, Tetsuya Kajimoto, Manabu Node, Reiko Tanaka, Manabu Nishizawa, Hironori Ohtsu, Noriyuki Suzuki, Koichi Saito
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 17
  
  Pages: 2736-2748
- Data Source
  KAKENHI-PROJECT-18590022
[Journal Article] Synthesis of DL-standishinal anad its related compounds for the studies on structure-activity relationship of inhibitory activity against aro matase2007
- Author(s)
  Manabu Node
- Journal Title
  
  Bioorganic & Medicinal Chemistry 15
  
  Pages: 2736-2748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590022
[Journal Article] Efficient Route to 4a-Methyltetrahydrofluprenes : A Total Synthesis of (土)- Dichroanal B via Intramolecular Heck Reaction.2006
- Author(s)
  Loic Planas, Muneto Mogi, Hirofumi Takita, Tetsuya Kajimoto, Manabu Node
- Journal Title
  
  Journal of the Organic Chemistry 71・7
  
  Pages: 2896-2898
- Data Source
  KAKENHI-PROJECT-18590022
[Journal Article] Synthesis of Amaryllidaceae alkaloids, siculine, oxocrinine, epicrinine, and buflavine.2004
- Author(s)
  Sumiaki Kodama, Hirofumi Takita, Tetsuya Kajimoto, Kiyoharu Nishide, Manabu Node
- Journal Title
  
  Tetrahedron 60
  
  Pages: 4901-4907
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590022
[Journal Article] Total synthesis of (-)-galanthamine by remote asymmetric induction.2004
- Author(s)
  Sumiaki Kodama, Yoshio Hamashima, Kiyoharu Nishide, Manabu Node
- Journal Title
  
  Angew.Chem.Int.Ed. 43
  
  Pages: 2659-2661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590022
[Journal Article] Total Synthesis of )-)-Galanthamine by Remote Asymmetric Induction2004
- Author(s)
  S.Kodama, Y.Hamashima, K.Nishide, M.Node
- Journal Title
  
  Angew.Chem.Int.Ed. 43
  
  Pages: 2659-2661
- Data Source
  KAKENHI-PROJECT-16590022
[Journal Article] An efficient synthesis of(±)-narwedine and(±)-galanthamine by an improved phenolic oxidative coupling・2001
- Author(s)
  Manabu Node et al.
- Journal Title
  
  Angew. Chem. Int. Ed. 40・16
  
  Pages: 3060-3062
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590022
[Journal Article] An efficient synthesis of (±)-narwedine and (±)-galanthamine by an improved phenolic oxidative coupling.2001
- Author(s)
  Manabu Node, Sumiaki Kodama, Yoshio Hamashima, Takahiro Baba, Norimitsu Hamamichi, Kiyoharu Nishide
- Journal Title
  
  Angew.Chem.Int.Ed. 40(16)
  
  Pages: 3060-3062
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590022
[Presentation] GnT-Vを標的とした三糖誘導体の合成研究2010
- Author(s)
  有光健治、木村寛之、梶本哲也、野出學
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山大学(岡山)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] GnT-Vを標的とした三糖誘導体の合成研究2010
- Author(s)
  有光健治, 木村寛之, 梶本哲也, 野出學
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山大学(岡山)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] チオグリコシド誘導体の組み合わせによる効率的グリコシル化反応の開発2009
- Author(s)
  有光健治, 吉増秀礼, 梶本哲也, 野出學
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(千葉)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] チオグリコシド関連糖供与体の化学選択的グリコシル化反応2009
- Author(s)
  有光健治、吉増秀礼、梶本哲也、野出學
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] Chemoselective Glycosylation by Using Thioglycoside from Odorless Benzenethiol2009
- Author(s)
  K.Arimitsu, H.Yoshimasu, T.Kajimoto,M.Node
- Organizer
  The 11^<th> International Kyoto Conference on New Aspects of Organic Chemistry
- Place of Presentation
  リーガロイヤルホテル京都(京都)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] チオグリコシド関連糖供与体の化学選択的グリコシル化反応2009
- Author(s)
  有光健治, 吉増秀礼, 梶本哲也, 野出學
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] チオグリコシド誘導体の組み合わせによる効率的グリコシル化反応の開発2009
- Author(s)
  有光健治、吉増秀礼、梶本哲也、野出學
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(千葉)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] N-アセチルグルコサミン転移酵素Vの受容体基質となる三糖誘導体の合成研究2009
- Author(s)
  有光健二, 木村寛之, 小関稔梶本哲也, 野出學
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市(京都国際会館)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] 三糖構造を有する糖脂質類似体の合成研究2008
- Author(s)
  有光健二, 木村寛之, 小関稔梶本哲也, 野出學
- Organizer
  第58回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸市(神戸薬科大学)
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] Abeoabietane型ジテルペノイド類の効率的不斉全合成2008
- Author(s)
  野出学
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 三糖構造を有する糖類似体の合成研究2008
- Author(s)
  有光健二, 加藤孝博, 木村寛之小関稔, 梶本哲也, 野出學
- Organizer
  第38回複素環化学討論会
- Place of Presentation
  福山市(広島県民文化センターふくやま)
- Data Source
  KAKENHI-PROJECT-20590022
[Presentation] 分子内不斉Heck反応を用いたDichroanal類の不斉全合成2007
- Author(s)
  野出學, 他
- Organizer
  第51会香料・テルペンおよび精油化学に関する討論会
- Place of Presentation
  長浜バイ大学
- Year and Date
  2007-11-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Synthesis of Dichroanals Using Intramolecular Asymmetric Heck Reaction.2007
- Author(s)
  Manabu Node, et. al.
- Organizer
  第51回香料・テルペンおよび精油化学に関する討論会(51st TEAC)
- Place of Presentation
  Nagahama
- Year and Date
  2007-11-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 分子内不斉Heck反応を用いたDichroanal A,Bの全合成2007
- Author(s)
  野出學, 他
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the total synthesis of dichroanals A and B.2007
- Author(s)
  Manabu Node, et. al.
- Organizer
  日本薬学会第127年会
- Place of Presentation
  Toyama
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 分子内不斉Heck反応を用いたDichroanal類の不斉全合成2007
- Author(s)
  野出学
- Organizer
  第51回香料・テルペンおよび精油化学に関する討論会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 分子内不斉Heck反応を用いたDichroanal類の不斉全合成2007
- Author(s)
  野出學, 他
- Organizer
  第57回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪薬科大学
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Development of Asymmetric Reactions and Total Synthesis of Natural Products2007
- Author(s)
  Manabu Node
- Organizer
  The Nineteenth French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  富山国際センター
- Year and Date
  2007-05-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the total synthesis of dichroanals A and B.2007
- Author(s)
  Manabu Node, et. al.
- Organizer
  第57回日本薬学会近畿支部総会・大会
- Place of Presentation
  Osaka
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Development of Asymmetric Reactions and Total Synthesis of Natural Products.2007
- Author(s)
  Manabu Node
- Organizer
  19th French-Japanese Symposium on Medicinal and Fine Chemistry.
- Place of Presentation
  Toyama Intern. Conference Center
- Year and Date
  2007-05-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the synthesis of dichroanal B.2006
- Author(s)
  Manabu Node, et. al.
- Organizer
  International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Year and Date
  2006-07-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 動的速度論分割に基づく不斉反応の開発と応用2006
- Author(s)
  野出學, 他
- Organizer
  日本薬学会関東支部第31回学術講演会
- Place of Presentation
  東京・薬学会館
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the total synthesis of dichroanals A and B.2006
- Author(s)
  Manabu Node, et. al.
- Organizer
  第26回有機合成若手セミナー
- Place of Presentation
  Osaka
- Year and Date
  2006-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Development of asymmetric reactions based on dynamic kinetic resolution and its application.2006
- Author(s)
  Manabu Node
- Organizer
  日本薬学会関東支部第31回学術講演会
- Place of Presentation
  Tokyo
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the synthesis of dichroanal B2006
- Author(s)
  Manabu Node, et. al.
- Organizer
  International Conference on Biodiversity and Natural Products
- Place of Presentation
  京都国際会議場
- Year and Date
  2006-07-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] 分子内不斉Heck反応を用いたDichroanal A,Bの全合成2006
- Author(s)
  野出學, 他
- Organizer
  第26回有機合成若手セミナー
- Place of Presentation
  大阪
- Year and Date
  2006-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the synthesis of dichroanal B2006
- Author(s)
  野出學, 他
- Organizer
  第48回天然有機化合物討論会
- Place of Presentation
  仙台国際センター
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590022
[Presentation] Asymmetric Heck reaction via dynamic kinetic resolution and its application for the synthesis of dichroanal B.2006
- Author(s)
  Manabu Node, et. al.
- Organizer
  48th Symposium on the chemistry of natural products
- Place of Presentation
  Sendai
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590022

1. NISHIDE Kiyoharu (10237711)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. FUJI Kaoru (20027056)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KAWABATA Takeo (50214680)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAGAO Yoshimitsu (40027074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OCHIAI Masahito (50127065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 井上武久 (50176434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KAJIMOTO Tetsuya (80185777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
8. SAI MIDORI (20170483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小関稔 (40465597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results

NODE Manabu 野出 學

野出 学 ノデ マナブ

Research Projects

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Development of a Novel Asymmetric Heck Reaction based on Dynamic Kinetic Resolution and Its ApplicationPrincipal Investigator

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Study on Effective Asymmetric Total Synthesis of Gallanthamine, a Drug for Alzheimer's disease.Principal Investigator

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Studies on the construction of multi-contiguous asymmetric synthesis using mercapto alcohol as a chiral templatePrincipal Investigator

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新しい作用機序を有する新規ピリミジン系抗ガン剤の開発研究Principal Investigator

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Review Section

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Studies on the Development of Novel Asymmetric Multi-Functional MPV ReductionPrincipal Investigator

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生体触媒による脱エステル化反応を用いる新規不斉合成の開発研究Principal Investigator

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不斉ニトロオレフィン化反応の改良と新規不斉合成素子の開発研究Principal Investigator

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新しい脱モノチオアセタール化反応剤の開発とその不斉合成への応用Principal Investigator

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HSAB則に基づく新反応の開発;環式ニトロ化合物の不斉合成Principal Investigator

Principal Investigator

NODE Manabu 野出學

野出学ノデマナブ