HIGUCHI Yasunori 樋口安典

… Alternative Names

Researcher Number	60040284
External Links
Affiliation (based on the past Project Information) *help	2009 – 2011: Oita University, 全学研究推進機構, 教授 2006 – 2007: 大分大学, 先端医工学研究センター, 教授 1999 – 2002: 大分医科大学, 医学部, 助教授 1991 – 1997: 大分医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Experimental pathology / Orthopaedic surgery / General surgery / Surgical dentistry Except Principal Investigator Experimental pathology / Biological Sciences
Keywords	Principal Investigator CD14 / transgene / osteopontin / オステオポンチン / LPS / shock / トランスジェニックマウス / TNF / recombinant / metallothionein … More Except Principal Investigator オステオポンチン / CD14 / MS2 / osteopontin / cDNA / genome / expression / recombinant / mouse and human / B16 / ハプトタキシス / トランスジェニックマウス / オステオポンチン遺伝子発現 / 血清アミロイドA / SAA3 / 逆転写 / グルココルチコイド / アンチセンスmRNA / ジメチルヒドラジン / ベニバナ油 / 高オレイン酸ベニバナ油 / 大腸がん / 発がんプロモーション / リン脂質 / スフィンゴミエリン / ネルボン酸 / ADAM15 / バリアント蛋白 / Lck / Hck / Src / T細胞活性化 / ADAM6 / shedding / ADAMファミリー / スプライスバリアント / Srcファミリー / ADAM8 / CD156 / アポトーシス / メタロプロテアーゼ / ジスインテグリン / トランスジェニック / ADAM17 / TACE / ADAM / 単クローン抗体 / AD56 / マクロファ-ジ遺伝子 / マクロファ-ジcDNA / マクロファ-ジ / 膜蛋白 / 分泌蛋白 / Sppー1 Less

From analysis of osteopontin function to development of preventive and medical treatment for osteoporosis.Principal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Oita University
Mechanisms ofpromoting the bone invasion of cancer cells by osteopontinPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Oita University
ADAMファミリーメンバーのクローニングと機能解析
- Principal Investigator
  
  山本俊輔
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Beppu University
  大分医科大学
In vivo analysis of osteopontin functionPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Oita Medical University
不飽和脂肪酸による発がんプロモーションと抑制
- Principal Investigator
  
  竹下正純
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  大分医科大学
Fundamental studies of regularion for endotoxin shock by CD14Principal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Oita Medical University
Molecular pathology of osteopontin transgenic micePrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Oita Medical University
マクロファージ特異的遺伝子発現マウスの作出Principal Investigator
- Principal Investigator
  
  樋口安典
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  大分医科大学
Regulation and analysis of systemic and local effect of TNFPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yasunori
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Oita Medical University
オステオポンチンーガン転移における意義と発現機序の解析
- Principal Investigator
  
  YAMAMOTO Shunsuke
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
新しい急性期反応物質LIPの分子病理学的研究
- Principal Investigator
  
  秋月真一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  大分医科大学
Molecular, cellular and pathological analysis of structure and function of macrophages
- Principal Investigator
  
  YAMAMOTO Shunsuke
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Oita Medical University

All 2009 2007

All Journal Article Presentation

[Journal Article] Elevated soluble ADAM8 in BALF in patients with eosinophilic pneumonia.2007
- Author(s)
  Matsuno O., Miyazaki E., Nureki S., Ueno T., Ando M.., Ito K.., Kumamoto T. and Higuchi Y.
- Journal Title
  
  International Archives of Allergy and Immunology 142
  
  Pages: 285-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592190
[Presentation] オステオポンチンが破骨細胞に及ぼす影響-オステオポンチントランスジェニックマウスの解析-2009
- Author(s)
  片岡晶志、樋口安典、津村弘
- Organizer
  第24回日本整形外科基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21591951
[Presentation] オステオポンチンが破骨細胞に及ぼす影響-オステオポンチントランスジェニックマウスの解析-2009
- Author(s)
  片岡昌志, 樋口安典, 津村弘
- Organizer
  日本整形外科基礎学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21591951

1. AKIZUKI Shinishiro (80159334)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. SETOGUCHI Mihoko (20236110)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. YAMAMOTO Shunsuke (90040188)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KATAOKA Masashi (40301379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. YOSHIDA Seiji (70182764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 竹下正純 (50019551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 調恒明 (50179058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松浦恵子 (00291542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 泥谷直樹 (80305036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 矢澤一良

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIGUCHI Yasunori 樋口 安典

樋口 安典 ヒグチ ヤスノリ

Research Projects

Research Products

Co-Researchers

From analysis of osteopontin function to development of preventive and medical treatment for osteoporosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms ofpromoting the bone invasion of cancer cells by osteopontinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ADAMファミリーメンバーのクローニングと機能解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo analysis of osteopontin functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

不飽和脂肪酸による発がんプロモーションと抑制

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Fundamental studies of regularion for endotoxin shock by CD14Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular pathology of osteopontin transgenic micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージ特異的遺伝子発現マウスの作出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Regulation and analysis of systemic and local effect of TNFPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

オステオポンチンーガン転移における意義と発現機序の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

新しい急性期反応物質LIPの分子病理学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular, cellular and pathological analysis of structure and function of macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Elevated soluble ADAM8 in BALF in patients with eosinophilic pneumonia.2007

Author(s)

Journal Title

Data Source

[Presentation] オステオポンチンが破骨細胞に及ぼす影響-オステオポンチントランスジェニックマウスの解析-2009

Author(s)

HIGUCHI Yasunori 樋口安典

樋口安典ヒグチヤスノリ