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SASAKI Hiroko  佐々木 洋子

ORCIDConnect your ORCID iD *help
Researcher Number 60045424
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2002: Sapporo Medical University, Cancer Research Institute, School of Medicine, Assist.Prof., 附属がん研究所, 講師
2001: 札幌医科大学, 医学部・附属がん研究所, 講師
1999: Cancer Res. Inst., Sch. Of Medicine, Assist. Prof., 医学部・付属がん研究所, 講師
1996 – 1999: 札幌医科大学, 医学部・附属がん研究所, 講師
1998: 札幌医科大学, 附属がん研究所, 講師 … More
1993: 札幌医科大学, 付属がん研究所, 講師
1993: 札幌医科大学, 医学部・付属がん研究所, 講師
1993: Sapporo Medical University, Cancer Research Institute, Assistant Professor, 医学部・付属癌研究所, 講師
1992: 札幌医科大学, 附属癌研究所, 講師
1991: Sapporo Medical College, Cancer Research Institute, Assistant Prof., 癌研究所, 講師
1990: 札幌医科大学癌研究所, 講師
1989: 札幌医科大学, がん研究所, 講師
1987 – 1988: 札幌医科大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Cell biology
Except Principal Investigator
General medical chemistry
Keywords
Principal Investigator
CAKβ / Hic-5 / FAK / タンパク質チロシンキナーゼ / PYK2 / protein-tyrosine kinase / チロシンリン酸化 / 焦点接着 / SH3 domain / nuclear translocation … More / tyrosine-phosphorylation / SH2ドメイン / SH3ドメイン / 核移行 / Focal Adhesion / CAKbeta / focal adhesion kinase / 神経細胞株 / 組み換えレトロウィルス / フォーカル・アドヘジョン・キナーゼ / ポリメラーゼ連鎖反応 / レトロウイルスベクター / 細胞接着斑 / フォーカルアドヘジョンキナーゼ / CBP-1 / 細胞内局在性 / in situ hybridizaion / 免疫組織化学 / パキシリン … More
Except Principal Investigator
CAKβ / タンパク質チロシンキナーゼ / PYK2 / チロシンリン酸化 / 焦点接着 / Hic-5 / 核移行 / tyrosine-phosphorylation / protein-tyrosine kinase / ホスホリパーゼC / T細胞受容体 / SUMO ligase / nuclear translocation / cDNA発現クローニング / イノシトールリン酸 / CD3複合体 / GFP / SH2ドメイン / 細胞内局在性 / SH3ドメイン / ホスホリパ-ゼC / 細胞内遊離Ca^<2+>濃度 / 血小板由来成長因子 / SH3 domain / アンドロゲン受容体 / Graf / Peptide Mass Fingerprinting法 / SH3 / SH2 domain / cDNA expression cloning / CAKbeta / パキシリン / FAK / GST fusion protein / Src homology 3 domain / バキュロウィルス発現系 / B細胞抗原受容体 / ダブルチロシンモチーフ / Fyn / GST融合タンパク質 / Src相同領域3 / cytoplasmic free Ca^<2+> concentration / recombinant baculovirus / phospholipase C / src homology region 2 / tyrosine phosphorylation / protein tyrosine kinase / T cell receptor / 単クロ-ン抗体 / 可変領域 / 組み換えバキュロウイルス / src相同領域2 / タンパク質チロシンキナ-ゼ / Gタンパク質 / 細胞内遊離カルシウムイオン濃度 / 線維芽細胞 / 細胞内遊離カルシウムイオン濃度。 / ホルボールエステル / コレラ毒素 / T細胞 / OKT3 / GDPβS / GTPγS / フッ化アルミニウム / GTP結合タンパク質 / CBP-1 / in situ hybridization / 免疫組織化学 / 単クローン抗体 / アデノウイルスベクター / Efs / ラスp21タンパク質 / ラス遺伝子 Less
  • Research Projects

    (15 results)
  • Co-Researchers

    (9 People)
  •  Studies on the function of a protein-tyrosine kinase CAKβ/PYK2 and a protein Hic-5 binding to CAKβ

    • Principal Investigator
      SASAKI Terukatsu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  第二のFAK族チロシンキナーゼCAKβの機能に関する研究

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
  •  FAK族キナーゼCAKβと焦点接着局在Hic-5による細胞形態とJNKの調節機構

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
  •  Studies on the function of Hic-5, a CAKβ-binding protein localized at focal adhesionsPrincipal Investigator

    • Principal Investigator
      SASAKI Hiroko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  A study on the signaling pathway activating CAKbeta, second protein-tyrosine kinase of the FAK subfamily.

    • Principal Investigator
      SASAKI Terukatsu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  新たにクローン化したCAKβおよびEfsの細胞接着、分化増殖、癌化における役割

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  新たにクローン化した第2のFAK、CAKβ、の活性化機序とシグナル伝達機構の研究

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  第2のFAK族キナーゼ、CAKβ、のカドヘリンを介するシグナル受容における役割Principal Investigator

    • Principal Investigator
      佐々木 洋子
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Sapporo Medical University
  •  Mechanism of Signal Transduction by Nonreceptor Protein-tyrosine Kinases

    • Principal Investigator
      SASAKI Terukatsu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  Establishment of Neural Cell Lines by Introducing cDNA for Immortalization ; Studies on their Surface Antigens and Growth/Differentiation FactorsPrincipal Investigator

    • Principal Investigator
      SASAKI Hiroko
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical University
  •  Mechanism of Activation of Signaling Enzymes in Inositol Lipid Metabolism Following Ligation of Cell Surface Receptors in T Lymphocytes

    • Principal Investigator
      SASAKI Terukatsu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Sapporo Medical College
  •  PDGF受容体およびT細胞受容体を介するホスホリパ-ゼCの活性化機構

    • Principal Investigator
      SASAKI Terukatsu
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  T細胞抗原受容体およびNK細胞表面膜受容体を介する細胞内二次シグナルの生成機構

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  PDGF受容体およびT細胞抗原受容体を介するホスホリパーゼCの活性化機構-GTP結合タンパク質の関与しない共役機構の解析-

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  T細胞抗原受容体およびNK細胞表面膜受容体を介する細胞内二次シグナルの生成機構

    • Principal Investigator
      佐々木 輝捷
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  • 1.  SASAKI Terukatsu (00045494)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 2.  ISHINO Masaho (30232325)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  AOTO Hiroshi (30285001)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  YAMASHITA Yumi
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NAGURA Kazuko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  遠藤 俊明 (90213595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  三高 俊広 (50231618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  望月 洋一 (40045381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  鈴木 るみ子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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