HARADA Shoji 原田勝二

Researcher Number	60086618
External Links
Affiliation (based on the past Project Information) *help	2001: 筑波大学, 社会医学系, 教授 2000: 筑波大学, 社会医学系, 助教授 1986 – 1998: 筑波大学, 社会医学系, 助教授 1995: 筑波大学, 医学専門学群, 助教授
Review Section/Research Field	Principal Investigator Legal medicine / Public health/Health science / 公衆衛生学 / Psychiatric science Except Principal Investigator Legal medicine / Public health/Health science
Keywords	Principal Investigator Alcoholism / 遺伝的多型 / Genetic polymorphism / アルコール依存症 / PCR / GABA / GABA autoreceptor / GABA-Transaminase / ALA / ALA-Dehydratase … More / Gs protein / genetic polymorphism / 幻覚 / アルコ-ル依存症 / Human specific DNA / Y-Chromosome specific DNA / Microsatellite DNA / Minisatellite DNA / MVR-PCR / Tandem repeats / Heterozeigosity / DNA Profiling / GSTM1 gene deletion / CYP1A1 / polymorphism / lung cancer / genetic association / case control study / Xenobiotics / genetic risk factor / Promoter / 遺伝的リスク因子 / Cholecystokinin gene / Cholecystokinin B receptor / Genetic risk factor / ADH2 / ALDH2 / CYP2E1 / GSTM1 / NQO2 / プロ-ブ / 血痕 / 親子鑑定 / DNA Fingerprint法 / 血清蛋白型 / 個人識別 / DNA多型 / pHYN22 / MCT118 / VNTR / GStπ gene / ORM型 / Factor1 / 唾液アミラ-ゼ / フィンガ-プリント法 / PCR法 / 蛋白多型 / 人獣鑑定 / 性別鑑定 / RFLP_S / DNA / 赤血球酵素 / 血清蛋白 / Probe / Blood stain / Paternity testing / DNA fingerprinting / Serum protein / Individual identification / アルコール離脱症状 / autoreceptor / ALA-dehydratase / 遺伝子型 / GSSG / 酵素活性阻害 / GABA受容体 / ALA dehydratase / ALAD1型 / GABAーTransaminase / アルコ-ル離脱症状 / Gs蛋白 / Adenyl Cyclase / 赤血球膜 / GABAT多型 / Y-chromosome specific DNA / Tandem Repeats / genetric risk factor / 遺伝的危険因子 / 対照研究 / コレシストキニンB受容体 / セロトニン1A受容体 / ミトコンドリアDNA / コレシストキニン遺伝子 / アルコール性肝障害 / Aldehyde dehydrogenase / Risk factor / MAZ / Cis-element / アルコール離脱症 / 転写因子(Sp1) / radioimmunoassay / CCKペプチド濃度 / Serotonin Receptor / Promoter region / Case control study / Serotonin 1A receptor / Mitochondria DNA / アルコール / 代謝 / 飲酒量 / 離脱症状 / GSTM1遺伝子 / NQO1遺伝子 / NQO2遺伝子 / 多型性変異 / 転写制御領域 / CCKA受容体遺伝子 / CCKB受容体遺伝子 / CCK遺伝子 / Association Analysis / 転写因子 / 人種差 / Alcohol / Metabolisms / Alcohol consumption / アルデヒド脱水素酵素 / アルデヒド代謝 / 遺伝マ-カ- / 分子遺伝学 / アルコ-ル代謝 / 分子遺伝子 / アイソザイムV型の多型 / アルコール依存症の疫学 / Genetic Polymorphism / Aldehyde Dehydrogenase / Aldehyde Metabolism / Genetic Marker / Molecular Genetics … More Except Principal Investigator HLA / モンゴロイド / 形質人類学 / 人類遺伝学 / ALDH / DNA多型 / DNA / 遺伝子頻度 / PCR法 / 古人骨 / 個人識別 / 親子鑑定 / PCR / 人獣鑑別 / DNA polymorphism / 日本人 / 形態小変異 / 日本列島人 / ヒトゲノム情報 / DNA鑑定 / 遺伝子診断 / ヒトゲノムプロジェクト / 倫理的、法的、社会的問題 / 出生前診断 / アンジオテンシノーゲン遺伝子 / ハプロタイプ / 高血圧 / 24時間蓄尿 / アンギオテンシノーゲン遺伝子 / 本態性高血圧 / 24時間血圧 / ナトリウム摂取 / 遺伝子多型 / DNAフィンガ-プリント / プロ-ブ / RFLP(制限酵素断柿長多型) / サザンハイブリダイゼ-ション / ミトコンドリアDNA多型 / PCR(ポリメラ-ゼ連鎖反応) / VNTR(高変異反復配列) / RFLPs(制限酵素断片長多型) / サザンプロッテイング / 制限酵素 / サザンハイブリダイゼイション / Ha-ras遺伝子 / 個人性別 / DNA Polymorphism / DNA Fingerprint / Probe / RFLPs / Southern hybridization / Mitochondrial DNA / VNTR / ヒト特異的DNA / マイクロサテライト / ゲノム・サブトラクション / チンパンジー・ゲノムDNA / 人種特異的DNA / ヒト特異性DNA / ヒト特異性 / ヒト特異的DNA領域 / チンパンジ-・ゲノムDNA / サザン・ハイブリダイゼ-ション / Human-specific DNA / Specie identification / Microsatellite / Genome subtraction / Personal identification / Human race-specific DNA / 人類化石 / MONGOLOID / PHYSICAL ANTHROPOLOGY / HUMAN GENETICS / HUMAN SKELETAL REMAINS / MORPHOLOGY / GENE FREQUENCY / 血漿フィブリノーゲン / 血清総コレステロール / 疫学研究 / 環境要因 / 遺伝要因 / 虚血性心疾患 / 脳卒中 / 心筋梗塞 / Plasma fibrinogen / Sernm total cholesterol / Epidemiologic study / Environmental factors / Genetic factors / Coronary heart disease / Stioke / 血液型 / 血清型 / 酵素型 / 人特異形質 / 遺伝形質 / 電気泳動 / 免疫化学 / 白血球酵素型 / 赤血球酵素型 / 血液型物質 / ラジオイムノアッセイ,等電点電気泳動法 / 酵素抗体法 / レクチン / Blood Group / Blood Group Substance / Species Indentification / Immunoassay / Electrophoresis / Genetic Marker / Polymorphism Less

本態性高血圧の遺伝要因とナトリウム摂取の相互作用に関する疫学研究
- Principal Investigator
  
  磯博康
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  University of Tsukuba
Developmental research on the novel genetic factors related to alcohol metabolismPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Jiro, 原田勝二
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  University of Tsukuba
本態性高血圧の遺伝要因とナトリウム摂取に関する疫学・分子生物学的研究
- Principal Investigator
  
  SHIMAMOTO Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  University of Tsukuba
Molecular-Ecogenetic study on the ethiology of alcoholismPrincipal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  University of Tsukuba
DNA鑑定に関する包括的研究
- Principal Investigator
  
  KATSUMATA Yoshinao
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Nagoya University
Intensive study for evaluation and establishment of DNA identity in criminal justice.Principal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  University of Tsukuba
Epidemiology and moleculorbiology on emvircnemnted and genetic factors for atheis sclirosis and thrombasis
- Principal Investigator
  
  SHIMAMOTO Takashi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  University of Tsukuba
Epidemiological and molecular genetic study for environmental and occupational cancers.Principal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  University of Tsukuba
拡散集団の起源・系統(自然人類学)
- Principal Investigator
  
  百々幸雄
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Genetic and Epidemiological study on alcohol withdrawalPrincipal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  公衆衛生学
- Research Institution
  University of Tsukuba
Isolation of Human-specific DNA Regions and its Forensic Application to Personal Identification
- Principal Investigator
  
  MISAWA Shogo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  University of Tsukuba
拡散集団の起源・系統(自然人類学)
- Principal Investigator
  
  百々幸雄
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
拡散集団の起源・系統(自然人類学)
- Principal Investigator
  
  DODO Yukio
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Application of New Genetic Markers on Proteins, Enzymes and DNA to Forensic Medicine.Principal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  University of Tsukuba
Basic Studies on DNA Polymorphism for Application to Foresic Medicine
- Principal Investigator
  
  MISAWA Shogo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  University of Tsukuba
ORIGINES AND AFFINITIES OF DIPERSAL POPULATIONS (PHYSICAL ANTHROPOLOGY)
- Principal Investigator
  
  DODO Yukio
- Project Period (FY)
  1989 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Epidemiological study on isozyme variants of aldehyde dehydrogenase and alcoholism.Principal Investigator
- Principal Investigator
  
  HARADA Shoji
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Tsukuba
Investigation of human genetic marker and human specific component in body fluids and its application to forensic medicine
- Principal Investigator
  
  YOSHIOKA Naofumi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  Akita University

All 2003 2002 2001 2000 1999 Other

All Journal Article

[Journal Article] Association Analyses between Polymorphisms of the Phase II Detoxification Enzymes (GSTM1, NQO1, NQO2) and Alcohol Withdrawal Symptoms.2003
- Author(s)
  Okubo T, Harada S, Higucbi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Association Analyses between Polymorphisms of the Phase II Detoxification Enzymes (GSTM1, NQO1, NQO2) and Alcohol Withdrawal Symptoms.2003
- Author(s)
  Okubo T, Harada, S, Higuchi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Investigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism.2002
- Author(s)
  Okubo T, Harada S, Higuchi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res. 26(8)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] lnvestigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism.2002
- Author(s)
  Okubo T, Harada S, Higucbi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res. 26(8):2S-5S.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphisms of the CCK, CCKAR and CCKBR genes : an association with alcoholism study.2001
- Author(s)
  Okubo T, Harada S.
- Journal Title
  
  J Stud Alcohol ; 62(4)
  
  Pages: 413-421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorders.2001
- Author(s)
  Harada, S, Agarwal DP, Nomura F, Higuchi S
- Journal Title
  
  Alcohol Clin Exp Res, 25 71S-75S
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorders .2001
- Author(s)
  Harada, S, Agarwal DP, Nomura F, Higuchi S
- Journal Title
  
  Alcohol Clin Exp Res 25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphism of the neuropeptide Y gene : an association study with alcohol withdrawal.2001
- Author(s)
  Okubo T, Harada S.
- Journal Title
  
  Alcohol Clin Exp Res 25(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphism of the 5'-flanking region of the CYP2E1 gene : an association study with alcoholism.2001
- Author(s)
  Itoga S, Harada S, Nomura F.
- Journal Title
  
  Alcohol Clin Exp Res. 25(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphisms of the CCK, CCKAR and CCKBR genes : an association with alcoholism study.2001
- Author(s)
  Okubo T, Harada S.
- Journal Title
  
  J Stud Alcohol ; 62(4):413-421.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphism of the 5'-flanking region of the CYP2E1 gene : an association study with alcoholism.2001
- Author(s)
  Itoga S, Harada S, Nomura F.
- Journal Title
  
  Alcohol Clin Exp Res. 25(6):11S-5S
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Polymorphism of the neuropeptide Y gene : an association study with alcohol withdrawal.2001
- Author(s)
  Okubo T, Harada S.
- Journal Title
  
  Alcohoi Clin Exp Res 25(6):59S-62S
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Genetic polymorphism of the CCK gene in patients with alcohol withdrawal symptoms.2000
- Author(s)
  Okubo T, Harada S, Higuchi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res. 24(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] Genetic polymorphism of the CCK gene in patients with alcohol withdrawal symptoms.2000
- Author(s)
  Okubo T, Harada S, Higuchi S, Matsushita S.
- Journal Title
  
  Alcohol Clin Exp Res.; 24(4)12S-4S.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] A novel polymorphism (-357 G/A) of the ALDH2 gene : linkage disequilibrium and an association with alcoholism.1999
- Author(s)
  Harada S, Okubo T, Nakamura T, Fujii C, Nomura F, Higuchi S, Tsutsumi M.
- Journal Title
  
  Alcohol Clin Exp Res. Jun ; 23(6)
  
  Pages: 958-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470106
[Journal Article] A novel polymorphism (-357 G/A) of the ALDH2 gene : linkage disequilibrium and an association with alcoholism.
- Author(s)
  Harada S, Okubo T, Nakamura T, Fujii C, Nomura F, Higuchi S, Tsutsumi M.
- Journal Title
  
  Alcohol Clin Exp Res. 1999 Jun;23(6):958-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12470106

1. DODO Yukio (50000146)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. OMOTO Keiichi (10011503)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 徳永勝士 (40163977)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. JUJI Takeo (20009997)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SAITOU Naruya (30192587)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SUZUKI Koichi (60171211)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. ISO Hiroyasu (50223053)

# of Collaborated Projects: 3 results

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8. MISAWA Shogo (50086534)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. TANAKA Einosuke (30138416)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. YOSHIOKA Hisabumi (80108935)

# of Collaborated Projects: 2 results

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11. HUKUSHIMA Hirobumi (70135218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. SHIMOJO Nobuhiro (00080622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KATSUMATA Yoshinao (30109326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SHIMAMOTO Takashi (50143178)

# of Collaborated Projects: 2 results

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15. KOIKE Kazuko (60110508)

# of Collaborated Projects: 2 results

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16. ISHIMOTO Gouishi (30024673)

# of Collaborated Projects: 2 results

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17. SATO Shinji (90162437)

# of Collaborated Projects: 2 results

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18. ODA Susumu (90049156)

# of Collaborated Projects: 2 results

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19. NOMURA Fumio (80164739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
20. NAKAMURA Jiro (10110751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
21. 平井百樹 (60156635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. UMEZU Kazuo (10091828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOKOI Takeshi (70135226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. WASHIO Keiko (60230942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. UEDA Shintaryoh (20143357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. BABA Hisao (90049221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KUROSAKI Kunihiko (60240701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YAMANOUCHI Haruo (30134919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TAMAKI Yoshihiro (20028377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MURAKAMI Masataka (30010078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. MORITA Nobuaki (10251068)

# of Collaborated Projects: 1 results

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32. SAGISAKA Kaoru (70006740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 長沼範良 (40164454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 鈴森薫 (80117829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 伊東研祐 (00107492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 谷川武 (80227214)

# of Collaborated Projects: 1 results

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37. 岩佐峰雄 (00021452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 寺沢浩一 (40142715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 進藤祥子 (10134090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. SAGAI Masaru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 向山明孝

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 豊増翼

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. TOYOMASU Tasuku

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HARADA Shoji 原田 勝二

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Developmental research on the novel genetic factors related to alcohol metabolismPrincipal Investigator

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Molecular-Ecogenetic study on the ethiology of alcoholismPrincipal Investigator

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Intensive study for evaluation and establishment of DNA identity in criminal justice.Principal Investigator

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Epidemiological and molecular genetic study for environmental and occupational cancers.Principal Investigator

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Genetic and Epidemiological study on alcohol withdrawalPrincipal Investigator

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Application of New Genetic Markers on Proteins, Enzymes and DNA to Forensic Medicine.Principal Investigator

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HARADA Shoji 原田勝二