KIGUCHI Kazushige 木口一成

… Alternative Names

木口一成キグチカズシゲ

Less

Researcher Number	60101911
Other IDs
External Links
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2006 – 2010: 聖マリアンナ医科大学, 医学部, 教授 2002: 聖マリアンナ医大, 医学部, 助教授 1997 – 2002: 聖マリアンナ医科大学, 医学部, 助教授 1991 – 1992: 慶應義塾大学, 医学部, 講師 1988 – 1989: 慶應義塾大学, 医学部・産婦人科, 講師 1987: 慶応義塾大学, 医学部・産婦人科, 講師
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 卵巣癌 / Lewis^x / 糖鎖遺伝子 / 腹膜播種 / 血液型物質 / sulfatide / 婦人科腫瘍学 / pathology / proteomics / protein … More / oncology / gynecologic oncology / 婦人科学 / 病理学 / プロテオミクス / 蛋白質 / 腫瘍学 / type I carbohydrate chain / fucosyltransferase / carbohydrate chain gene / Ovarian cancer / I型糖鎖 / フコース転移酵素 / dissemination / Flow cytometry / Cell adhesion / TLC-immunostaining / Glycolipid / 転移能 / HLA-24拘束性CTLクローン / 抗ErbB-2抗体 / 卵巣癌培養細胞株 / EGFR / ErbB-2 / 複合糖脂質 / 卵巣癌腹膜播種 / RMG-1 / clear cell carcinoma / peritoneal dissemination / ovarian cancer / 不死化腹膜細胞 / 細胞接着 / 卵巣明細胞腺癌株 / RMG-I / スルファチド / 卵巣明細胞腺癌 / GAT / Type III GSLs / MRG-I / N-cerebronyl phitosphingosine / I^3SO_3-GalCer / mucinous cystadenocarcinoma / Ovarian Tumors / Glycosphingolipids / Nーcerebronyl phytosphingosine / galactosyl transferase / sulfoーtransferase / 癌化に伴う糖代謝異常 / 粘液性腺腫 / 子宮頚部扁平上皮癌 / 小胞体 / ゴルジ体 / モノクローナル抗体MRG-1 / ムチン性卵巣癌 / 癌関連ガラクトース転移酵素(GAT) / タイプIIIA型糖脂質 / MRG-1 / Le^a,Le^b / Sulfo-GalCer / 粘液性嚢胞腺癌 / 卵巣腫瘍 / 糖鎖 / トランスポーター / 婦人科癌 / 糖鎖抗原 / 抗癌剤耐性 / ABCトランスポーター / 糖脂質 … More Except Principal Investigator Flow cytometry / Monoclonal antibody / Sulfotransferase / Sulfatide / Endometrium / Glycolipids / フローサイトメトリー / パラグロボシド / ヒト型HMSTー1抗体 / 血液型物質ルイスb / マウス型MSNー1抗体 / ヒト子宮内膜 / 子宮腔内抗原測定 / モノクローナル抗体MSN-1,MSN-2,フローサイトメトリー / Forssman抗原 / GA1,GM3,Sulfatide / ステロイドホルモン / マウス子宮内膜 / I型糖鎖 / ヒト型モノクロ-ナル抗体 / 血液型糖鎖 / フロ-サイトメトリ / モノクロ-ナル抗体 / 硫酸基転移酵素 / スルファチド / 子宮内膜 / 糖脂質 Less

Optimization of chemotherapy of ovarian cancer as an indicator of transporter expression and glycolipidPrincipal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St.Marianna University School of Medicine
A trial at developing molecular-targeted therapy of ovarian cancer using a molecular chaperon heat shock protein(Hsp) as the targetPrincipal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St.Marianna University School of Medicine
Study of effect of a carbohydrate chain gene on the characteristics of ovarian cancer cellsPrincipal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St. Marianna University School of Medicine
Analysis and Clinical Significance on the Carbohydrate Chain Gene related to the Peritoneal Dissemination of Ovarian Cancer.Principal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St.Marianna University School of Medicine
Analysis of the molecular bases and the expression of the Lewis^x sugar chain, which may account for the high dissemination potential.Principal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St.Marianna Univ.School of Medicine
Glycosphingolipids of various human ovarian tumorsPrincipal Investigator
- Principal Investigator
  
  KIGUCHI Kazushige
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University School of Medicine
Analysis of Glycolipids in Human Endometrium - using mouse and human monoclonal antibodies -
- Principal Investigator
  
  NOZAWA Shiro
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University

All 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] 婦人科がん化学療法の有害事象-卵巣機能不全2010
- Author(s)
  鈴木直、杉下陽堂、小林陽一、木口一成、石塚文平
- Journal Title
  
  産科と婦人科 77巻
  
  Pages: 586-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] Performance status不良の進行婦人科癌に対するweekly paclitaxel+carboplatin療法の有用性2010
- Author(s)
  矢作奈美子、小林陽一、細沼信示、大原樹、近藤春裕、鈴木直、木口一成、石塚文平
- Journal Title
  
  日本婦人科腫瘍学会雑誌 29巻
  
  Pages: 112-117
- NAID
  10029412160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 子宮内膜間質肉腫18例の臨床病理学的検討2010
- Author(s)
  大原樹、小林陽一、鈴木直、木口一成、新井正秀、角田新平、上坊敏子、平澤猛、村松俊成、三上幹夫
- Journal Title
  
  日本婦人科腫瘍学会雑誌 28巻
  
  Pages: 144-149
- NAID
  10026446941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 婦人科にて初期治療を施行したGIST症例の臨床病理学的検討2009
- Author(s)
  今井愛、二井美津穂、上坊敏子、海野信也、平澤猛、村松俊成、三上幹男、鈴木直、小林陽一、木口一成
- Journal Title
  
  日本婦人科腫瘍学会誌 27巻
  
  Pages: 63-68
- NAID
  10025202791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] Ovarian toxicity of paclitaxel and effect on fertility in the rat2009
- Author(s)
  Watatu Tarumi、Nao Suzuki、Noriyuki Takahashi、Yoichi Kobayashi、Kazushige Kiguchi、Kahei Sato、Bunpei Ishizuka
- Journal Title
  
  J.Obstet.Gynaecol.Res 35巻
  
  Pages: 1321-1325
- NAID
  10025339881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 再発卵巣癌に対するIrinotecan+Cisplatin療法の有用性2009
- Author(s)
  矢作奈美子、小林陽一、大原樹、近藤春裕、鈴木直、木口一成、石塚文平
- Journal Title
  
  癌と科学療法 36巻
  
  Pages: 2583-2586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma2009
- Author(s)
  Miyazawa Masaki、Yasuda Masanori、Fujita Mariko、Kajiwara Hiroshi、Hirabayashi Kenichi、Takekoshi Susumu、Hirasawa Takeshi、Murakami Masaru、Ogane Naoki、Kiguchi Kazushige、Ishiwata Isamu、Mikami Mikio、Osamura R Yoshiyuki
- Journal Title
  
  Pathology International 59巻
  
  Pages: 19-27
- NAID
  10027378890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] TGP(Thermoreversible Gelation Polymer)を用いた感受性試験に基づく婦人科癌化学療法の個別化の試み2009
- Author(s)
  小林陽一、大原樹、鈴木直、木口一成、石塚文平
- Journal Title
  
  日本婦人科腫瘍学会雑誌 27巻
  
  Pages: 37-41
- NAID
  10025202415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 卵巣がん診療の最前線2009
- Author(s)
  木口一成
- Journal Title
  
  聖マリアンナ医科大学雑誌 37
  
  Pages: 287-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 境界悪性傍卵巣腫瘍の1例2009
- Author(s)
  矢作奈美子、栗林靖、和田康菜、大熊克彰、水原浩、相田芳夫、鈴木直、小林陽一、木口一成、石塚文平
- Journal Title
  
  日本産科婦人科学会関東連合地方部会誌 46巻
  
  Pages: 373-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary2009
- Author(s)
  Yoshioka Norihito、Suzuki Nao、Uekawa Atsushi、Kiguchi Kazushige、IshizukaBunpei
- Journal Title
  
  HUMAN CELL 4巻
  
  Pages: 94-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 卵巣がん診療の最前線2009
- Author(s)
  木口一成
- Journal Title
  
  聖マリアンナ医科大学雑誌 37巻
  
  Pages: 287-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 抗癌剤耐性細胞とペルオキシゾーム欠損細胞における糖脂質合成の促進2008
- Author(s)
  岩森正男、岩森由里子、斎藤真木子、田中京子、石渡勇、木口一成
- Journal Title
  
  JCBL(第50回日本脂質生化学会講演要旨集) 50巻
  
  Pages: 131-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 【卵巣癌治療の最前線6】卵巣癌の維持化学療法2008
- Author(s)
  鈴木直、大原樹、小林陽一、木口一成
- Journal Title
  
  臨床婦人科産科 62巻
  
  Pages: 1321-1325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] VP-16内服にてCRを得た再発卵巣癌の一例2008
- Author(s)
  古屋直樹、小林陽一、桑原真理子、吉岡伸人、渡辺弓花、吉岡範人、渡辺敦子、大原樹、和田康菜、井上憲、奥田順子、鈴木直、木口一成、石塚文平
- Journal Title
  
  第378回日本産科婦人科学会神奈川地方部会誌 44巻
  
  Pages: 25-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591965
[Journal Article] 卵巣癌に対する分子標的治療の現況。2007
- Author(s)
  木口一成
- Journal Title
  
  聖マリアンナ医科大学雑誌 35
  
  Pages: 5-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] 卵巣癌に対する分子標的治療の現況2007
- Author(s)
  木口一成
- Journal Title
  
  聖マリアンナ医科大学雑誌 35
  
  Pages: 5-21
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Cytology and histology of corpus uteri cancer.2007
- Author(s)
  Kazushige Kiguchi
- Journal Title
  
  Clinical Gynecology and Obstertrics 61
  
  Pages: 120-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Surgery conducted during pregnancy : conization.2007
- Author(s)
  Kazushige Kiguchi.
- Journal Title
  
  Perinatal Medicine(Supple) 37
  
  Pages: 315-318
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] 妊娠中の手術-円錐切除-2007
- Author(s)
  木口一成
- Journal Title
  
  周産期医学増刊号 37
  
  Pages: 315-318
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Current status of molecular targeting therapy for ovarian cancer.2007
- Author(s)
  Kazushige Kiguchi.
- Journal Title
  
  St. Maranna Medical Journal 35
  
  Pages: 5-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] 妊娠中の手術-円錐切除-。2007
- Author(s)
  木口一成
- Journal Title
  
  周産期医学増刊号 37
  
  Pages: 315-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] 子宮体癌の細胞診・組織診2007
- Author(s)
  木口一成, 他
- Journal Title
  
  臨床婦人科産科 61
  
  Pages: 120-125
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance.2006
- Author(s)
  Kazushige Kiguchi
- Journal Title
  
  Cancer Science 97(12)
  
  Pages: 1321-1326
- NAID
  10020387745
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] 子宮頸部初期病変(CIN)の取り扱い2006
- Author(s)
  木口一成, 他
- Journal Title
  
  産婦人科の実際 55
  
  Pages: 1499-1507
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Management of early cervical intraepothelial neoplasia(CIN)2006
- Author(s)
  Kazushige Kiguchi
- Journal Title
  
  Obstrail and Gynecological Practice 55
  
  Pages: 1499-1507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance.2006
- Author(s)
  Kazushige Kiguchi
- Journal Title
  
  Cancer Science 97
  
  Pages: 1321-1326
- NAID
  10020387745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Journal Article] Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance2006
- Author(s)
  Kazushige Kiguchi, et. al.
- Journal Title
  
  Cancer Science 97
  
  Pages: 1321-1326
- NAID
  10020387745
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591849
[Presentation] Cancer stem cells of ovarian cancer and the resistance to anticancer drugs2008
- Author(s)
  Kazushige Kiguchi
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591965
[Presentation] Cancer stem cells of ovarian cancer and the resistance to anticancer drugs.2008
- Author(s)
  Kazushige Kiguchi, et al.
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591965
[Presentation] HSPを標的とした卵巣癌分子標的治療の作用メカニズムの解析2006
- Author(s)
  木口一成, 他
- Organizer
  第58回日本産科婦人科学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Presentation] HSPを標的とした卵巣癌分子標的治療の作用メカニズムの解析2006
- Author(s)
  木口一成, 他
- Organizer
  第65回日本癌学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Presentation] A trial at developing molecular-targeted therapy of ovarian cancer using a molecular chaperon heat shock protein(Hsp) as the target.2006
- Author(s)
  Kazushige Kiguchi, et. al.
- Organizer
  The 65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849
[Presentation] Analysis of the action mechanism involved in molecular targeting therapy for ovarian cancer using HSP as a target.2006
- Author(s)
  Kazushige Kiguchi, et. al.
- Organizer
  58th Annual Congress of the Japan Society of Obstetrics and Gynecology.
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591849

1. YOSHIDA Norio (10267619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. OHARA Tatsuru (30445879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. KAMEI Kazuhiko (40224688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HORIKOSHI Hiroshi (80247379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IWATA Masanori (80257401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKUMA Yoshiaki (70386952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NOZAWA Shiro (90051557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UDAGAWA Yasuhiro (80118918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MUKAI Makio (50101895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高松潔 (30206875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIGUCHI Kazushige 木口 一成

木口 一成 キグチ カズシゲ

Research Projects

Research Products

Co-Researchers

Optimization of chemotherapy of ovarian cancer as an indicator of transporter expression and glycolipidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A trial at developing molecular-targeted therapy of ovarian cancer using a molecular chaperon heat shock protein(Hsp) as the targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of effect of a carbohydrate chain gene on the characteristics of ovarian cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis and Clinical Significance on the Carbohydrate Chain Gene related to the Peritoneal Dissemination of Ovarian Cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the molecular bases and the expression of the Lewis^x sugar chain, which may account for the high dissemination potential.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Glycosphingolipids of various human ovarian tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Glycolipids in Human Endometrium - using mouse and human monoclonal antibodies -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 婦人科がん化学療法の有害事象-卵巣機能不全2010

Author(s)

Journal Title

Data Source

[Journal Article] Performance status不良の進行婦人科癌に対するweekly paclitaxel+carboplatin療法の有用性2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 子宮内膜間質肉腫18例の臨床病理学的検討2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 婦人科にて初期治療を施行したGIST症例の臨床病理学的検討2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Ovarian toxicity of paclitaxel and effect on fertility in the rat2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 再発卵巣癌に対するIrinotecan+Cisplatin療法の有用性2009

Author(s)

Journal Title

Data Source

[Journal Article] Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma2009

Author(s)

Journal Title

NAID

Data Source

KIGUCHI Kazushige 木口一成

木口一成キグチカズシゲ