KOYAMA Junko 小山淳子

Researcher Number	60102109
Other IDs
Affiliation (based on the past Project Information) *help	2012: 神戸薬科大学, 薬学部, 講師 2010: Kobe Pharmaceutical University, 薬学部, 准教授 2002 – 2009: 神戸薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Physical pharmacy Except Principal Investigator Laboratory medicine / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 第1還元電位 / EBV-EA活性化抑制効果 / サイクリックボルタンメトリー / 酸化還元電位 / Cyclic voltammetry / Heteroquinone / First reduction potential / Emodin / Inhibitory effects on EBV-EA activation / Anti-tumor promoter … More / Oxidation-reduction potential / Anthraquinone / キノン / 抗発癌プロモーター / ヘテロキノン / エモジン / 抗発がんプロモーター / アントラキノン / 電子的性質 / 細胞毒性 / 抗菌活性 / プロトベルベリン / EBV-EA活性化抑制試験 / ケミカルメディエーター / KU812細胞 / LC-MS / 抗アレルギー活性 / リグナン / フラボノイド / 生物活性物質 / 分析化学 … More Except Principal Investigator 抗体 / 抗体工学 / antibody / 一本鎖Fvフラグメント / 抗体ライブラリー / エストラジオール / ハプテン / 単一ドメイン抗体 / antibody-engineering / single-domain antibody / cyclodextrin / immunosensing / complex / acceptor / hapten / アクセプター / シクロデキストリン / イムノセンシング / 複合体 / フクセプター / selection / cleavable biotin / genetic engineering / affinity / phage antibody / phage display / single-chain Fv fragment / 新和力 / 選択法 / cleavableビオチン / 遺伝子工学 / 親和力 / ファージ抗体 / ファージディスプレイ / herbicide / permeability transition pore / voltage-dependent anion channel / superoxide / NADH-quinone oxidoreductase / mitochondria / paraquat / 電位依存性アニオンチャンネル / 電位依存性アニオンチャネル / ミクロソーム / チトクロムP450 / 解毒作用 / ミトコンドリア / 急性毒性 / 除草剤 / パラコート / ジゴキシン / ライブラリー / モニタリング / バイオマーカー / 免疫複合体 / シングルドメイン抗体 / イムノメトリックアッセイ / 分子認識 / ナノ抗体 Less

Generation of recombinant antibody libraries that facilitate highly sensitive monitoring of low molecular weight biomarkers
- Principal Investigator
  
  KOBAYASHI Norihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe Pharmaceutical University
Development and application of the high-throughput prediction method of activity for the bioactive substancesPrincipal Investigator
- Principal Investigator
  
  KOYAMA Junko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kobe Pharmaceutical University
Development of monitoring systems for bioactive haptens with high sensitivity using "nano-antibodies" as a molecular recognition unit
- Principal Investigator
  
  KOBAYASHI Norihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe Pharmaceutical University
Development of the anti-cancer promoting activity prediction method for the quinones which assume oxidation-reduction potential as a key parameterPrincipal Investigator
- Principal Investigator
  
  KOYAMA Junko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kobe Pharmaceutical University
Highly sensitive immunosensing based on new generation antibodies against a hapten-acceptor complex
- Principal Investigator
  
  KOBAYASHI Norihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe Pharmaceutical University
Generation of mutant antibodies with ultrahigh affinity based on a novel and universal selection method and their application to trace analysis
- Principal Investigator
  
  KOBAYASHI Norihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe Pharmaceutical University
Acute Cytotoxic Mechanisms and Detoxic Mechanisms of Paraquat Poisoning
- Principal Investigator
  
  HIRAI Keiichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kanazawa Medical University

All 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Geranyl Derivatives of Isoquinoline Alkaloids Show Incresed Biologycal Activities2010
- Author(s)
  Yumi Nishiyama, Junko Koyama, et al.
- Journal Title
  
  HETEROCYCLES
  
  Volume: 81 Pages: 1193-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Geranyl Derivatives of Isoquinoline Alkaloids Show Incresed Biologycal Activities2010
- Author(s)
  Yumi Nishiyama, Kinuko Iwasa, Suguru Okada, Sousuke Takeuchi, Masataka Moriyasu, Miyoko Kamigauchi, Junko Koyama, Atsuko Takeuchi, Harukuni Tokuda, Hye-Sook Kim, Yusuke Wataya, Kazuyoshi, Takeda, Yi-Nan Liu, Pei-Chi Wu, Kenneth F.Bastow, Toshiyuki Akiyama, Kuo-Hsiung Lee
- Journal Title
  
  HETEROCYCLES 81
  
  Pages: 1193-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Biotransformation of Phenolic Tetrahydroprotoberbe-rines in Plant Cell Cultures Followed by LC-NMR, LC-MS, and LC-CD2010
- Author(s)
  Kinuko Iwasa, Wenhua Cui, Teturo Takahashi, Yumi Nishiyama, Miyoko Kamigauchi, Junko Koyama, Atsuko Takeuchi, Masataka Moriyasu, Kazuyoshi Takeda
- Journal Title
  
  J.Nat.Prod. 73
  
  Pages: 115-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Biotransformation of Phenolic Tetrahydroprotoberberines in Plant Cell Cultures Followed by LC-NMR, LC-MS, and LC-CD2010
- Author(s)
  Kinuko Iwasa, Junko Koyama
- Journal Title
  
  J.Nat. Prod. 73
  
  Pages: 115-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Correlation between Cytotoxic Activities and Reduction Potentials of Heterocyclic Quinones2010
- Author(s)
  Junko Koyama, Izumi Morita, Takao Yamori
- Journal Title
  
  Molecules 15
  
  Pages: 6559-6569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Cytotoxic Activities and Reduction Potentials of Heterocyclic Quinones2010
- Author(s)
  Junko Koyama, et al.
- Journal Title
  
  Molecules
  
  Volume: 15 Pages: 6559-6569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Development of an LC-ESI-MS/MS method for the determination of histamine : Application to the quantitative measurement of histamine degranulation by KU812 cells2009
- Author(s)
  Junko Koyama
- Journal Title
  
  J. Chromatogr. B 877
  
  Pages: 207-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS2009
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 7493-7499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Development of an LC-ESI-MS/MS method for the determination of histamine : Application to the quantitative measurement of histamine degranulation by KU812 cells.2009
- Author(s)
  J.Koyama, A.Takeuchi, C.Tode, M.Shimizu, I.Morita, M.Nobukawa, M.Nobukawa Nobukawa, N.Kobayashi
- Journal Title
  
  J.Chromatogr.B 877
  
  Pages: 207-212
- NAID
  10028011987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Development of an LC-ESI-MS/MS method for the determi-nation of histamine : Application to the quantitative measurement of histamine degranulation by KU812 cells2009
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography B 877
  
  Pages: 207-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS2009
- Author(s)
  J.Koyama, A.Takeuchi, I.Morita, Y.Nishino, M.Shimizu, M.Inoue, N.Kobayashi
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 7493-7499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Development of an LC-ESI-MS/MS method for the determination of histamine: Application to the quantitative measurement of histamine degranulation by KU812 cells.2009
- Author(s)
  J. Koyama, A. Takeuchi, C. Tode, M. Shimizu, I. Morita, M. Nobukawa, M. Nobukawa, N. Kobayashi
- Journal Title
  
  J. Chromatogr. B 877
  
  Pages: 207-212
- NAID
  10028011987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives.2008
- Author(s)
  J. Koyama, Y. Nishino. I. Morita, N. Kobayashi, T. Osakai, H. Tokuda
- Journal Title
  
  Bioorg. Med. Chem. Lett. 18
  
  Pages: 4106-4109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids2008
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 263
  
  Pages: 61-66
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives2008
- Author(s)
  J.Koyama, Y.Nishino, I.Morita, N.Kobayashi, T.Osakai, H.Tokuda
- Journal Title
  
  Bioorg.Med.Chem.Lett. 18
  
  Pages: 4106-4109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids2008
- Author(s)
  J. Koyama, I. Morita, N. Kobayashi, T. Konoshima, M. Takasaki, T. Osakai, H. Tokuda
- Journal Title
  
  Cancer Lett. 263
  
  Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivative2008
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorganic & Medicinal Chemical Letters 18
  
  Pages: 4106-4109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids2008
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 263
  
  Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids.2008
- Author(s)
  Junko Koyama, Izumi Morita, Norihiro Kobayashi, Takao Konoshima, Modori Takasaki, Toshiyuki Osakai, Harukuni Tokuda
- Journal Title
  
  Cancer Lett. 263
  
  Pages: 61-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Correlation between reduction potentials and inhibitions of Epstein-Barrvirus activation by anthraquinone derivatives2008
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorg. Med. Chem. Lett. 18
  
  Pages: 4106-4109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590046
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis2007
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography A 1145
  
  Pages: 183-189
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis.2007
- Author(s)
  Junko Koyama, Izumi Morita, Norihiro Kobayashi
- Journal Title
  
  J. Chromatogr. A 1145
  
  Pages: 183-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Simultaneous determinations of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis2007
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography A 1145
  
  Pages: 183-189
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] in rhubarb by high-performance liquid chromatography and capillary electrophoresis.2007
- Author(s)
  J. Koyama, I. Morita, N. Kobayashi
- Journal Title
  
  J. Chromatogr. A 1145
  
  Pages: 183-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis2007
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography A 1145・1-2
  
  Pages: 183-189
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis2007
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography A 1145
  
  Pages: 183-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590576
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by highperformance liquid chromatography and capillary electrophoresis2007
- Author(s)
  Junko Koyama
- Journal Title
  
  Journal of Chromatography A 1145
  
  Pages: 183-189
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis.2007
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  J. Chromatogr. A 1145(1-2)
  
  Pages: 183-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives.2006
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Cancer Lett. 241(2)
  
  Pages: 263-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 241
  
  Pages: 263-267
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Antiallergic Activity of Aqueous Extracts and Constituents of Taxus yunnanensis2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 2310-2312
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Anti-infective quinone derivatives of recent patent.2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Recent Patents on Anti-Infective Drug Discovery 1
  
  Pages: 113-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Biological and Pharmaceutical Bulletin 29・11
  
  Pages: 2310-2312
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 241
  
  Pages: 263-267
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis.2006
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Biol. Pharm. Bull. 29(11)
  
  Pages: 2310-2312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Biological and Pharmaceutical Bulletin 29
  
  Pages: 2310-2312
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Anti-infective quinone derivatives of recent patents2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Recent Patents on Anti-Infective Drug Discovery 1
  
  Pages: 113-125
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives.2006
- Author(s)
  Junko Koyama, Munetaka Inoue, Izumi Morita, Norihiro Kobayashi Toshiyuki Osakai, Hoyoku Nishino, Harukuni Tokuda
- Journal Title
  
  Cancer Lett. 241
  
  Pages: 263-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives2006
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 241.2
  
  Pages: 263-267
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Antiallergic activity of aqueous extracts and constituents of Taxus Yunnanensis.2006
- Author(s)
  Junko Koyama, Izumi Morita, Norihiro Kobayashi, Keiichi Hirai, Eriko Simamura, Takahiro Nobukawa, Shigetoshi Kadota
- Journal Title
  
  Biol. Pharm. Bull. 29(11)
  
  Pages: 2310-2312
- NAID
  110004840413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Journal Article] Structure-activity relations of azafluorenone and azaanthra- quinone as antimicrobial compounds2005
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 15(4)
  
  Pages: 1079-1082
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Structure-activity relations of azafluorenone and azaanthraquinone as antimicrobial compounds2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15
  
  Pages: 1079-1082
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation of poly-substituted anthraquinones2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 225・2
  
  Pages: 193-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Simultaneous determination of anthraquinones, their 8-β-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis.2005
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin 53
  
  Pages: 573-575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Structure-activity relations of azafluorenone and azaanthraquinone as antimicrobial compounds2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 15
  
  Pages: 1079-1082
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Simultaneous determination of anthraquinones, their 8-beta-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Chemical and Pharmaceutical Bulletin 53・5
  
  Pages: 573-575
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Structure-activity relations of azafluorenone and azaanthraquinone as antimicrobial compounds.2005
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 15
  
  Pages: 1079-1082
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation of poly-substituted anthraquinones2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 225
  
  Pages: 193-198
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation of poly- substituted anthraquinones.2005
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Cancer Lett. 225(2)
  
  Pages: 193-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Simultaneous determination of anthraquinones, their 8-β-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Chemical and Pharmaceutical Bulletin 53
  
  Pages: 573-575
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Simultaneous determination of anthraquinones, their 8- beta-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis.2005
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Chem. Pharm. Bull. 53(5)
  
  Pages: 573-575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Structure-activity relations of azafluorenone and azaanthraquinone as antimicrobial compounds2005
- Author(s)
  Junko Koyama
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 15・4
  
  Pages: 1079-1082
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590504
[Journal Article] Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of 2-azaanthraquinones.2004
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Cancer Letters 212
  
  Pages: 1-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation of redox potentials and inhibitory effects on Epstein-Barr virus Activation of 2-azaanthraquinones2004
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 212
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of 2-azaanthraquinones2004
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 212
  
  Pages: 1-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Capillary electrophoresis of simultaneous determination of emodin, chrysophanol, and their 8-β-D-glucosides.2003
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin 51
  
  Pages: 418-420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of naphthoquinones2003
- Author(s)
  Junko Koyama
- Journal Title
  
  Cancer Letters 201
  
  Pages: 25-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Capillary electrophoresis of simultaneous determination of emodin, chrysophanol, and their 8-β-D-glucosides2003
- Author(s)
  Junko Koyama
- Journal Title
  
  Chemical and Pharmaceutical Bulletin 51
  
  Pages: 418-420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Journal Article] Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of naphthoquinones.2003
- Author(s)
  Junko Koyama et al.
- Journal Title
  
  Cancer Letters 201
  
  Pages: 25-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390180
[Presentation] LC-ESI-MS/MSによるTaxus yunnanensis中の抗アレルギー活性成分研究2010
- Author(s)
  清水香衣,小山淳子,森田いずみ,小林典裕
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-ESI-MS/MSによるPGD2・ヒスタミン測定を用いたリグナン類の抗アレルギー活性の評価2010
- Author(s)
  清水香衣,森田いずみ,竹内敦子,小林典裕,小山淳子,信川真智子,信川京子
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] Separation of O-methyl-ω-hydroxyemodins by LC-MS/MS using a β-cyclodextrin-bonded column2010
- Author(s)
  小山淳子,森田いずみ,竹内敦子,小林典裕
- Organizer
  15th International Cyclodextrin Symposium
- Place of Presentation
  ウィーン
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-ESI-MS/MSによるPGD_2・ヒスタミン放出抑制率測定を基盤とする抗アレルギー活性フラボノイドの探索2010
- Author(s)
  多賀詩織,小山淳子,森田いずみ,竹内敦子,小林典裕
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-APCI-MSを用いたエモジン2量体のRaji細胞内代謝物の検索2010
- Author(s)
  清水真希,小山淳子,森田いずみ,竹内敦子,小林典裕
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] Cacearia sylvestrisの成分研究2010
- Author(s)
  森田いずみ, 小山淳子
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-ESI-MS/MSによるPGD_2・ヒスタミン測定を用いたリグナン類の抗アレルギー活性の評価2010
- Author(s)
  清水香衣、小山淳子
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] Casearia sylvestrisの成分研究2010
- Author(s)
  森田いずみ,小山淳子,小林典裕
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-APCI-MS/MSを用いたエモジンのRaji 細胞内代謝物の同定2009
- Author(s)
  清水真希, 小山淳子, 竹内敦子, 森田いずみ, 小林典裕
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] プロトベルベリン型アルカロイドの生物活性と還元電位との相関性について2009
- Author(s)
  小山淳子,森田いずみ,小林典裕,岩佐衣子,守安正恭
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-MSを用いたケミカルメディエーター類の分析と抗アレルギー活性評価への応用2009
- Author(s)
  森田いずみ,小山淳子,小林典裕
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-APCI-MS/MSによるTaxus yunnanensis中の成分研究2009
- Author(s)
  森田いずみ, 小山淳子, 清水真希, 小林典裕, 信川真智子, 信川真貴子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] LC-APCI-MS/MSによるTaxus yunnanensisの成分研究2009
- Author(s)
  森田いずみ, 小山淳子, 清水真希, 小林典裕, 信川真智子, 信川真貴子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] LC-APCI-MS/MSを用いたエモジンのRaji細胞内代謝物の同定2009
- Author(s)
  清水真希, 小山淳子, 竹内敦子, 森田いずみ, 小林典裕
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] プロトベルペリン型アルカロイドの生物活性と還元電位との相関性について2009
- Author(s)
  小山淳子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-APCI-MS/MSによるTaxus yunnanensis中の成分研究2009
- Author(s)
  森田いずみ,小山淳子,清水真希,小林典裕,信川真智子,信川真貴子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] プロトベルベリン型アルカロイドの生物活性と還元電位との相関性について2009
- Author(s)
  小山淳子, 森田いずみ, 小林典裕, 岩佐衣子, 守安正恭
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] LC-ESI-MS/MSを用いたKU812細胞由来プロスタグランジンD2ならびにヒスタミンの分析2009
- Author(s)
  多賀詩織,小山淳子,森田いずみ,竹内敦子,清水真希,小林典裕
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  東大阪市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-ESI-MS/MSを用いたKU812細胞由来プロスタグランジンD_2ならびにヒスタミンの分析2009
- Author(s)
  多賀詩織, 小山淳子
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  東大阪市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] LC-APCI-MS/MSを用いたエモジンのRaji細胞内代謝物の同定2009
- Author(s)
  清水真希,小山淳子,竹内敦子,森田いずみ,小林典裕
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] プロトベルベリン型アルカロイドの生物活性と還元電位との相関性について2009
- Author(s)
  小山淳子, 森田いずみ, 小林典裕, 岩佐衣子, 守安正恭
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] トゲバンレイシAnnona muricata の成分研究2008
- Author(s)
  森田いずみ, 小山淳子, 小林典裕
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] 新規アレルギー活性成分の検索を目的とするLC/ESI-MSによるKU812細胞由来ヒスタミンの定量2008
- Author(s)
  小山淳子, 竹内敦子, 森田いずみ, 小林典裕, 信川真智子, 守川耕平, 岡野哲郎
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] プロトベルベリン類によるEpstein-Barr virus活性抑制と還元電流との相関性について2008
- Author(s)
  小山淳子, 森田いずみ, 小林典裕, 徳田春邦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] プロトベルベリン類によるEpstein-Barr virus活性抑制と還元電位との相関性について2008
- Author(s)
  小山淳子,森田いずみ,小林典裕,徳田春邦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] 新規抗アレルギー活性成分の検索を目的とするLC/ESI-MSによるKU812細胞由来ヒスタミンの定量2008
- Author(s)
  小山淳子
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Presentation] LC/ESI-MSによるKU812細胞由来ヒスタミンならびに生体アミン類の分析2008
- Author(s)
  清水真希,小山淳子,竹内敦子,森田いずみ,小林典裕
- Organizer
  第58回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] プロトベルベリン類によるEpstein-Barr virus活性抑制と還元電位との相関性について2008
- Author(s)
  小山淳子, 森田いずみ, 小林典裕, 徳田春邦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] LC/ESI-MSによるKU812細胞由来ヒスタミンならびに生体アミン類の分析2008
- Author(s)
  清水真希, 小山淳子, 竹内敦子, 森田いずみ, 小林典裕
- Organizer
  第58回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] プロトベルペリン類によるEpstein-Barr virus活性抑制と還元電位との相関性について2008
- Author(s)
  小山淳子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590046
[Presentation] トゲバンレイシAnnona muricataの成分研究2008
- Author(s)
  小山淳子
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Presentation] ヘテロキノン化合物のがん細胞増殖抑制効果と還元電位の相関性について2007
- Author(s)
  小山淳子, 森田いずみ, 小林典裕, 矢守隆夫
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] ヘテロキノン化合物のがん細胞増殖抑制効果と還元電位との相関性について2007
- Author(s)
  小山淳子
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Presentation] ヘテロキノン化合物のがん細胞増殖抑制効果と還元電位との相関性について2007
- Author(s)
  小山淳子
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] LC/APCI-MSを用いたエモジンのRaji細胞内活性代謝物の検索2007
- Author(s)
  小山淳子
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Presentation] LC/APCI-MSを用いたエモジンのRaji細胞内代謝物について2007
- Author(s)
  西野悠, 小山淳子, 竹内敦子, 森田いずみ, 小林典裕
- Organizer
  薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-29
- Data Source
  KAKENHI-PROJECT-19590576
[Presentation] エモジン誘導隊の発がんプロモーション抑制効果について2006
- Author(s)
  小山淳子
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042
[Presentation] LC/APCI-MSを用いたエモジンのRaji細胞内活性代謝物の検索2006
- Author(s)
  小山淳子
- Organizer
  第56回日本薬学会近畿支部総会
- Place of Presentation
  京都
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590042

1. MORITA Izumi (20299085)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
2. KOBAYASHI Norihiro (90205477)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
3. KATO Yoshinori (10368491)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. GOTO Junichi (80006337)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OYAMA Hiroyuki (80572966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIRAI Keiichi (60027092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIMADA Hiroki (60278108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOYAMA Junko 小山 淳子

Research Projects

Research Products

Co-Researchers

Generation of recombinant antibody libraries that facilitate highly sensitive monitoring of low molecular weight biomarkers

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Development and application of the high-throughput prediction method of activity for the bioactive substancesPrincipal Investigator

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Development of monitoring systems for bioactive haptens with high sensitivity using "nano-antibodies" as a molecular recognition unit

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Development of the anti-cancer promoting activity prediction method for the quinones which assume oxidation-reduction potential as a key parameterPrincipal Investigator

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Highly sensitive immunosensing based on new generation antibodies against a hapten-acceptor complex

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Generation of mutant antibodies with ultrahigh affinity based on a novel and universal selection method and their application to trace analysis

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Acute Cytotoxic Mechanisms and Detoxic Mechanisms of Paraquat Poisoning

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[Journal Article] Geranyl Derivatives of Isoquinoline Alkaloids Show Incresed Biologycal Activities2010

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[Journal Article] Geranyl Derivatives of Isoquinoline Alkaloids Show Incresed Biologycal Activities2010

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[Journal Article] Biotransformation of Phenolic Tetrahydroprotoberbe-rines in Plant Cell Cultures Followed by LC-NMR, LC-MS, and LC-CD2010

Author(s)

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[Journal Article] Biotransformation of Phenolic Tetrahydroprotoberberines in Plant Cell Cultures Followed by LC-NMR, LC-MS, and LC-CD2010

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[Journal Article] Correlation between Cytotoxic Activities and Reduction Potentials of Heterocyclic Quinones2010

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[Journal Article] Cytotoxic Activities and Reduction Potentials of Heterocyclic Quinones2010

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[Journal Article] Development of an LC-ESI-MS/MS method for the determination of histamine : Application to the quantitative measurement of histamine degranulation by KU812 cells2009

Author(s)

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[Journal Article] Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS2009

Author(s)

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Data Source

[Journal Article] Development of an LC-ESI-MS/MS method for the determination of histamine : Application to the quantitative measurement of histamine degranulation by KU812 cells.2009

Author(s)

KOYAMA Junko 小山淳子