SAKAMOTO Haruhiko 阪本晴彦

Researcher Number	60106549
Other IDs
Affiliation (based on the past Project Information) *help	2010 – 2012: 香川大学, 医学部, 教授 2005: Kagawa University, Faculty of Medicine, Prof., 医学部, 教授 2004: 国立大学法人香川大学, 医学部, 教授 2003: 香川大学, 医学部, 教授 2002: 香川医科大学, 医学部, 教授 1996 – 1999: Kagawa Medical University, Fuculty of Medicine, Professor, 医学部, 教授 1991 – 1994: 香川医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator Circulatory organs internal medicine / Biomedical engineering/Biological material science / Pathological medical chemistry / Neurology
Keywords	Principal Investigator RT-PCR / アミノ酸配列 / トランスフェリン / 白血球貧食能 / 人血小板 Except Principal Investigator 音速 / 超音波顕微鏡 / 音響特性 / 超音波 / MAGP-36 … More / PDX-1 / RNA editing / Calbrain / カルモジュリン依存性リン酸化酵素 / calbrain / p35 / Cdk5 / Propagation velocity / Acoustic microscopy / 動脈硬化 / acoustic cover membrane / 超音波減衰量 / microbubble / cell activation / cell function / irradiation / ultrasound / 微小気泡 / 細胞活性 / 細胞機能 / 超音波照射 / amyloidosis / acoustic microscopy / valvular regurgitation / elasticity / valvular tissue / sound speed / 僧帽弁 / 大動脈弁 / 組織 / 弁膜症 / アミロイドーシス / 弁逆流 / 弾性 / 弁組織 / immunosuppressant / neuropeptide Y receptor / Presenilin / brain ischemia / glutamate receptor / アルツハイマー脳 / GABAトランスポーター / カッパーオピオイドアゴニスト / 成長ホルモン促進ペプチド / p33ING1 / 情報伝達クロストーク / 脳 / クロストーク / 情報伝達 / ライディッヒ細胞 / 低体温法 / 虚血 / 海馬神経細胞 / 免疫抑制剤 / ニューロペプチドY受容体 / Presenilin-1 / 脳虚血 / グルタミン酸受容体 / acoustic property / propagation sound speed / endothel / atherosclerosis / acoustic microscope / 血管内皮 / calmodulin-dependent enzyme / ecalectin / ischemic neuronal death / kindlling / neuronal cell / calcium / 網膜 / タウ / 長期記憶増強 / リンホカイン / RU-51599 / 老化促進モデルマウス / 脳血管関門 / 成長ホルモン / カルモジュリン依存性酵素 / エカレクチン / 虚血性神経細胞死 / キンドリング / 脳神経細胞 / カルシウム / Density / Bulk modulus / Acoustic cover membrane / Stunned myocardium / Myocardial viability / Acoustic properties / ischemic preconditioning / 培養心筋細胞 / acousitc cover membrane / stunned myocardium / 心筋viability / 弾性特性 / Intima / Coronary artery / Ultrasonic attenuation / Arteriosclerosis / Quantitative assessment of tissue characteristics / tissue characterization / 内膜音速 / 減衰量 / 心筋 / 内膜 / 冠動脈 / 音響的定量評価 / 血液脳関門 / Glut5 / 血管脳関門 / CD36 / オステオポンチン / 血管性認知症 / 臨床神経形態学 / 音響インピーダンス / 体積弾性率 / 力学物性 Less

Development of new therapies for vascular dementia
- Principal Investigator
  
  UENO Masaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagawa University
Basic Studies on Sonodynamic Approaches of Cells by Ultrasound Activation.
- Principal Investigator
  
  SENDA Shoichi
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  KAGAWA UNIVERSITY
  香川大学(医学部)
Quantitative Tissue Characterization of Valvular Disease Based Upon Acoustic Properties Measured by High-frequency Ultrasound
- Principal Investigator
  
  SAKAMOTO Seiji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kagawa Medical University
Cross-talk regulation in multiple signaling systems
- Principal Investigator
  
  TAKAHARA Jiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Elucidation of the mechanisms of the impairment of functional neuron networks and establishment of the therapeutic strategies.
- Principal Investigator
  
  NAGAO Seigo, 入野昭三
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Physical characterization and dynamic pathophysiological study of endothel using scanning acoustic microscopy
- Principal Investigator
  
  SENDA Shoichi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kagawa Medical University
高周波超音波顕微鏡応用による生体組織微細構造と力学物性に関する研究
- Principal Investigator
  
  SENDA Shoichi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  香川医科大学
Evaluation of Progression of Arteriosclerosis by the Quantitative Assessment of Acoustic Tissue Characteristics Using Acoustic Microscopy
- Principal Investigator
  
  SENDA Shoichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kagawa Medical School
白血球の食作用を調節する血小板由来高分子量物質に関する研究Principal Investigator
- Principal Investigator
  
  阪本晴彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  香川医科大学
Evaluation of Progression of Arteriosclerosis by the Quantitative Assessment of Acoustic Tissue Characteristics Using Acoustic Microscopy
- Principal Investigator
  
  SENDA Shoichi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kagawa Medical School

All 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] Blood-brain barrier in SAMP82012
- Author(s)
  Ueno M. Sakamoto H, Akiguchi I
- Publisher
  Elesevier, The Senescence-Accelerated Mouse (SAM): Achievements and future directions
- Data Source
  KAKENHI-PROJECT-22590958
[Book] Transporters in the blood-brain barrier2011
- Author(s)
  Ueno M, Nakagawa T, Sakamoto H.
- Publisher
  Intech, Alzheimer's disease pathogenesis
- Data Source
  KAKENHI-PROJECT-22590958
[Journal Article] CD36 expression in the brains of SAMP82013
- Author(s)
  Wu B, Ueno M, Kusaka T, Miki T, Nagai Y, Nakagawa T, Kanenishi K, Hosomi N, Sakamoto H
- Journal Title
  
  Archives of Gerontology and Geriatrics
  
  Volume: 56 Pages: 75-79
- URL
  http://dx.doi.org/10.1016/j.archger.2012.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590958
[Journal Article] The expression of CD36 in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model.2011
- Author(s)
  Ueno M, Nakagawa T, Nagai Y, Nishi N, Kusaka T, Kanenishi K, Onodera M, Hosomi N, Huang C, Yokimise H, Tomimoto H, Sakamoto H.
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 37 Issue: 7 Pages: 727-737
- DOI
  10.1111/j.1365-2990.2011.01172.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590958, KAKENHI-PROJECT-22591201
[Journal Article] Blockage of AT1 receptors protects the blood-brain barrier and improve cognition in Dahl salt-sensitive hypertensive rats.2011
- Author(s)
  Pelish N, Hosomi N, Ueno M, Nakano D, Hitomi H, Mogi M, Shimada K, Kobori H, Horiuchi M, Sakamoto H, Matsumoto M, Kohno M, Nishiyama A.
- Journal Title
  
  Am J Hypertens
  
  Volume: 24 Issue: 3 Pages: 362-368
- DOI
  10.1038/ajh.2010.241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590958, KAKENHI-PROJECT-22790792
[Journal Article] Platelet high-density lipoprotein activates transferring-derived phagocytosis activators, MAPPs, following thrombin digestion2011
- Author(s)
  Sakamoto H, Wu B, Nagai Y, Tanaka S, Onodera M, Ogawa T, Ueno M
- Journal Title
  
  Platelets
  
  Volume: 22 Issue: 5 Pages: 371-379
- DOI
  10.3109/09537104.2010.533797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590958
[Journal Article] The expression of LDL receptor in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model2010
- Author(s)
  Ueno M, Wu B, Nakagawa T, Nagai Y, Onodera M, Huang C, Kusaka T, Kanenishi K, Sakamoto H
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 133 Issue: 6 Pages: 669-676
- DOI
  10.1007/s00418-010-0705-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] 酸化ストレスとアミロイドベータ蛋白輸送体の発現との関係について2012
- Author(s)
  上野正樹、松本晃一、田中澄子、阪本晴彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] 血液脳関門障害血管における CD36 の発現について2011
- Author(s)
  上野正樹、池田研二、阪本晴彦
- Organizer
  第52回日本神経病理学会学術研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] 血液脳関門障害血管における CD36 の発現について2011
- Author(s)
  上野正樹、松本晃一、阪本晴彦
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] Therapeutic targets for vascular dementia2010
- Author(s)
  Ueno M, Onodera M, Sakamoto H
- Organizer
  BIT's 1stannual world congress of NeuroTalk 2010
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] 血液脳関門障害血管における LDL 受容体の発現について2010
- Author(s)
  上野正樹、小野寺正征、松本晃一、阪本晴彦
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] 血液脳関門障害血管における LDL 受容体の発現について2010
- Author(s)
  上野正樹、小野寺正征、阪本晴彦
- Organizer
  第51回日本神経病理学会学術研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590958
[Presentation] Gene analyses in vessels with blood-brain barrier impairment2010
- Author(s)
  Ueno M, Onodera M, Sakamoto H
- Organizer
  XVIIth International Congress of Neuropathology
- Place of Presentation
  Salzburg, Austria
- Data Source
  KAKENHI-PROJECT-22590958

1. SENDA Shoichi (30145049)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. MATSUO Hirohide (90028514)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MASUGATA Hisashi (70263910)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MIZUSHIGE Katsufumi (90166009)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. UDA Hirotsugu (80107044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MORITA Hisaki (70145051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NISHIMURA Toshihiro (70117406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAGAO Seigo (60100947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TOKUDA Masaaki (10163974)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KOBAYASHI Ryoji (00020917)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TAKAHARA Jiro (00033085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 黄政龍 (10271511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. UENO Masaki (30322267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
14. MAETA Hajime (00075508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HIRASHIMA Mitsuomi (70109700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAKEUCHI Yoshiki (20116619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SUWAKI Hiroshi (10033367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SAKAMOTO Seiji (60253267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NOZAKI Shiro (80243773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FURUHATA Hiroshi (70056985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山内周 (60243755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 田中澄子 (70155141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小野寺正征 (40359922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. 入野昭三 (50033056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 板野俊文 (60145042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 畠瀬修 (50033220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 桑原宏子 (50243754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 永井雅巳 (40180450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 福永惠 (40283775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKAMOTO Haruhiko 阪本 晴彦

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白血球の食作用を調節する血小板由来高分子量物質に関する研究Principal Investigator

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[Book] Blood-brain barrier in SAMP82012

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[Book] Transporters in the blood-brain barrier2011

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[Journal Article] CD36 expression in the brains of SAMP82013

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[Journal Article] The expression of CD36 in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model.2011

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[Journal Article] Blockage of AT1 receptors protects the blood-brain barrier and improve cognition in Dahl salt-sensitive hypertensive rats.2011

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[Journal Article] Platelet high-density lipoprotein activates transferring-derived phagocytosis activators, MAPPs, following thrombin digestion2011

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SAKAMOTO Haruhiko 阪本晴彦