INOUE Hirokazu 井上弘

Researcher Number	60114203
Affiliation (based on the past Project Information) *help	2010: 埼玉大学, 名誉教授 2010: Saitama University, 理工学研究科, 名誉教授 2009: 埼玉大学, 理工学研究科, 教授 2008 – 2009: Saitama University, 大学院・理工学研究科, 教授 2007: Saitama University, Graduate School of Science and Engineering, Professor … More 2006: 埼玉大学, 大学院理工学研究科, 教授 2005: 埼玉大学, 理学部, 教授 1995 – 2001: Saitama University, Professor, 理学部, 教授 1992 – 1994: 埼玉大学, 理学部, 助教授 Less
Review Section/Research Field	Principal Investigator 遺伝 / Genetics/Genome dynamics / 遺伝学 Except Principal Investigator Breeding science / Applied genomics
Keywords	Principal Investigator アカパンカビ / 除去修復 / 遺伝子クローニング / 組み換え修復 / DNA修復 / 相同的組み換え / MRX / KU80 / KU70 / Neurospora … More / recQ / DNA repair / Neurospora crassa / RAD51 / mei-3 / ミトコンドリアDNA / ミトコンドリア / RIP / 紫外線損傷 / RFLPマッピング / Aspergillus / Ligase IV / Gene targeting / Nonhomologous end joining / 糸状菌 / 非相同組換え / Aserillus / Neurosora / Liase lV / 遺伝子ターゲッティング / 多目同末端結合 / コウジカビ / LigaseIV / 遺伝子ターゲッテイング / 非相同末端結合 / aging / Instability / mitochondria / queling / Recombination / DNAシークエンス / mus-10 / ゲノム不安定性 / クエリング / 寿命 / 組換え / Recombination repair / Cloning / Homologous recombination / recombinational repair / cloning / non-homologous recombination / homologous recombination / DNA修復欠損株 / 非相同的組み換え / 組換え修復 / 非相同的組換え / 相同的組換え / 変異原感受性 / 短寿命 / フラップエンドヌクレアーゼ / FENI / mus-38 / RAD2ホモログ / RAD1ホモログ / ヒスチジン感受性 / Mrellホモログ / Rad2ホモログ / Rad1ホモログ / RAD51ホモログ / ラスオンコジーン / Krev-1 / 紫外線 / TC(6-4)光産物 / チミンダイマー … More Except Principal Investigator 非相同末端結合 / 育種 / 相同組換え / DNA二本差切断修復 / 遺伝子ターゲッティング / KU70 / 遺伝子導入 / 担子菌 Less

非相同末端結合能破壊株を用いた高効率な遺伝子組換え作物作製技術の新規基盤開発
- Principal Investigator
  
  田中秀逸
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Breeding science
- Research Institution
  Saitama University
Mechanism of mtDNA deletion in short lived mutant of Neurospora.Principal Investigator
- Principal Investigator
  
  INOUE Hirokazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Saitama University
Host for highly efficient gene targeting in filamentous fungiPrincipal Investigator
- Principal Investigator
  
  INOUE Hirokazu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Saitama University
担子菌の標的遺伝子を高効率かつ高選択性をもって破壊する方法の開発
- Principal Investigator
  
  HATAKEYAMA Shin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Saitama University
アカパンカビのDNA除去修復機構の解明Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Saitama University
Characterization of the mus-10 and recQ genes involving in DNA repair, recombination, and senescencePrincipal Investigator
- Principal Investigator
  
  INOUE Hirokazu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  遺伝
- Research Institution
  Saitama University
アカパンカビのDNA除去修復機構の解明Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Saitama University
アカパンカビのDNA除去修復機構の解明Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
アカパンカビのDNA除去修復機構の解明Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
アカパンカビの組み換え修復にかかわる遺伝子の単離とその構造解析Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  遺伝
- Research Institution
  Saitama University
アカパンカビDNA修復遺伝子の構造と機能の解析Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
Cloning and Analysis of Neurospora genes which work on homologous recombinationPrincipal Investigator
- Principal Investigator
  
  INOUE Hirokazu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  遺伝
- Research Institution
  Saitama University
アカパンカビKrev-1遺伝子の構造と機能の解析Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
アカパンカビDNA修復遺伝子の構造と機能の解析Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
紫外線によって生じる遺伝子損傷の解析Principal Investigator
- Principal Investigator
  
  井上弘一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Saitama University
Effects of DNA repair on homologous and non-homologous recombinationPrincipal Investigator
- Principal Investigator
  
  INOUE Hirokazu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  遺伝学
- Research Institution
  Saitama University

All 2010 2008 2007 2006 Other

All Journal Article Presentation Patent

[Journal Article] Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence.2010
- Author(s)
  Kato, A., Kurashima, K., Chae, M., Sawada, S., Hatakeyama, S., Tanaka, S., Inoue, H.
- Journal Title
  
  Genetics
  
  Volume: 185 Pages: 1257-1269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570001
[Journal Article] Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence.2010
- Author(s)
  Kato A., Kurashima K., Chae M., Sawada S., Hatakeyama S., Tanaka S., Inoue H.
- Journal Title
  
  Genetics 185
  
  Pages: 1257-1269
- Data Source
  KAKENHI-PROJECT-20570001
[Journal Article] High efficient gene targeting on the AGAMOUS gene in an Arabidopsis AtLIG4 mutant.2010
- Author(s)
  S.Tanaka, C.Ishii, S.Hatakayama, H.Inoue
- Journal Title
  
  Biochem.Biophys.Research.Commun.
  
  Volume: 396 Pages: 289-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658003
[Journal Article] A defect of LigD (human Lig4 homolog) for nonhomologous end Joining significantly improves efficiency of gene-targeting in Aspergillus oryzae2008
- Author(s)
  Mizutani, o., Y. Kudo, A,. Saito, T. Matuura, H. Inoue, K. Abe, and K. Gomi.
- Journal Title
  
  Fungal Genet. Biol 45
  
  Pages: 878-889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] Detection of physical interactions by immunoprecipitation of FLAG-and HA-tagged proteins expressed at the his-3 locus in Neurospora crassa2007
- Author(s)
  T. Kawabata and H. Inoue
- Journal Title
  
  Fungal Genet. Newslett. 54
  
  Pages: 5-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] Neurospora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitilation in response to UV-iradiation2007
- Author(s)
  Kawabata, T., A. Kato, K. Suzuki, and H. Inoue.
- Journal Title
  
  Current Genetics 52
  
  Pages: 125-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] Detection of physical interactions by immunoprecipitation of FLAG-and HA-tagged proteins expressed at the his-3 locus in Neurospora crassa2007
- Author(s)
  T.Kawabata and H.Inoue
- Journal Title
  
  Fungal Genetics Newsletter 54
  
  Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] Nonhomologous chromosomal integration of foreign DNA is Completely dependent on MUS-53 (human Lig4 homolog) in Neurospora2006
- Author(s)
  Ishibashi, K., K. Suzuki, Y. Ando, C. Takakura, and H. Inoue.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103
  
  Pages: 14871-18476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] Growth defect and mutator phenotypes of RecQ-deficient Neurospora crassa mutants separately result from homologous recombination and nonhomologous end joining during repair of DNA double-strand breaks2006
- Author(s)
  A. Kato and H. Inoue
- Journal Title
  
  Genetics 172
  
  Pages: 113-125
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370001
[Journal Article] High efficient gene targeting on the AGAMOUS gene in an Arabidopsis AtLIG4 mutant.
- Author(s)
  S.Tanaka, C.Ishii, S.Hatakayama, H.Inoue
- Journal Title
  
  Biochem.Biophys.Research.Commun. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21658003
[Patent] 遺伝子ターゲッティングに伴うランダムインテグレーションを抑える方法2006
- Inventor(s)
  井上弘, 他5人
- Industrial Property Rights Holder
  埼玉大学
- Filing Date
  2006-05-11
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] New features of the mutagen sensitive-10 mutant reveal relationship between mitochondrial morphology and senescence in Neurospora crassa2010
- Author(s)
  Kurashima K., Kato A., Sawada S., Hatakeyama S., Chae M., Tanaka S., Inoue H.
- Organizer
  Neurospora 2010 meeting
- Place of Presentation
  Asilomar, California
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-20570001
[Presentation] Construction of host for high homologous recombination in Aspergillus oryzae2006
- Author(s)
  Youhei Kudo, Osamu Mizutani, Tomoki Matuura, Hirokazu Inoue, Keietsu Abe, and Katsuya Gomi
- Organizer
  58 th Society for Biotechnology in Japan
- Year and Date
  2006-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] Analysis of gene targeting mechanism in Neurospora2006
- Author(s)
  Chihiro Takakura, Yosinori Ando, Kazuma Ishibashi, Keiichiro Suzuki, and Hirokazu Inoue
- Organizer
  78 th Genetic Society of Japan
- Year and Date
  2006-09-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] Establishment of gene-targeting method in fungi2006
- Author(s)
  Hirokazu Inoue
- Organizer
  78 th Genetic Society of Japan
- Year and Date
  2006-09-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] DNA repair and Genomic Instability in Neurospora crassa2006
- Author(s)
  H. Inoue
- Organizer
  NEUROSPORA 2008
- Place of Presentation
  Asilomar, California, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] DNA repair and genomic instability in Neurospora crassa2006
- Author(s)
  Hirokazu Inoue
- Organizer
  2006 Neurospora meeting
- Place of Presentation
  in Asilomar, CA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] 糸状菌の効率的遺伝子破壊法:宿主としての非相同組換え欠損株2006
- Author(s)
  井上弘一
- Organizer
  第58回日本生物工学会
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2006-09-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370001
[Presentation] 糸状菌における遺伝子ターゲッティング機構の解析2006
- Author(s)
  井上弘一
- Organizer
  第78回日本遺伝学会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2006-09-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370001

1. ISHII Chizu (00114215)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. TANAKA Shuuitsu (90202431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. HATAKEYAMA Shin (00396665)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. GOMI Katsuya (60302197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ABE Keietsu (50312624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 阿部敬悦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

INOUE Hirokazu 井上 弘

Research Projects

Research Products

Co-Researchers

非相同末端結合能破壊株を用いた高効率な遺伝子組換え作物作製技術の新規基盤開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of mtDNA deletion in short lived mutant of Neurospora.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Host for highly efficient gene targeting in filamentous fungiPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

担子菌の標的遺伝子を高効率かつ高選択性をもって破壊する方法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アカパンカビのDNA除去修復機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Characterization of the mus-10 and recQ genes involving in DNA repair, recombination, and senescencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アカパンカビのDNA除去修復機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アカパンカビのDNA除去修復機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アカパンカビのDNA除去修復機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アカパンカビの組み換え修復にかかわる遺伝子の単離とその構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アカパンカビDNA修復遺伝子の構造と機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Cloning and Analysis of Neurospora genes which work on homologous recombinationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アカパンカビKrev-1遺伝子の構造と機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アカパンカビDNA修復遺伝子の構造と機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

INOUE Hirokazu 井上弘