SEKI Hiroko 関宏子

Researcher Number	60114245
Other IDs
Affiliation (based on the past Project Information) *help	2012: 千葉大学, 分析センター, 特任准教授 2007 – 2011: Chiba University, Chemical Analysis Center, associate professor 2004 – 2006: Chiba University, Chemical Analytical Center, Associate Professor, 分析センター, 助教授 2001 – 2004: 千葉大学, 分析センター, 助手
Review Section/Research Field	Principal Investigator Chemical pharmacy / Science and Engineering / Chemical pharmacy Except Principal Investigator Chemical pharmacy / Chemical pharmacy / Neurology / Physical pharmacy / Element strategy
Keywords	Principal Investigator CSI-MS / 水素結合 / イオン液体 / steroid compounds / hydrogen bonding / diffusion / PFG NMR / ステロイド化合物 / 分子拡散 / PFG-NMR … More / 分子間相互作用 / 緩和時間 / Narcissistic / ionic liquid / molecular interaction / タンパク質-薬物複合体 / クラスター / GSI-MS / 自己会合 / protein-ligand complex / X-ray analysis / chain structure / cold spray ionization (CSI)-MS / パルスシーケン / 生体分子 / 分子クラスター / HMBC / タンパク質-リガンド複合体 / X線解析 / 連鎖構造 / ^<31>P-NMR / ダイナミクス / 31P-NMR / 糖鎖構造 / 質量分析 / 核磁気共鳴 / 緩和時間(D_1, T_2) / 拡散係数(D) / コンタクトシフト / 溶液動態 / 緩和時間(T_1, T_2) / NMR / 分子間相亙作用 / CP-MAS / 固体NMR / 機能性化合物 / 併進ダイナミクス / クラスター構造 / 自己拡散係数 / ミセル構造 / 自己拡散測定 … More Except Principal Investigator DNA / GM1 / mass spectrometry / 質量分析 / コールドスプレー / cluster / RNA / catechin / HAS / high throughput analysis / cold-spray ionization / 分子会合 / 水素結合複合体 / NMR解析 / 単結晶X解析 / 分子拡散 / ビスグアニジン類 / 安息香酸 / クリスタルエンジニアリング / 分子化合物 / Morita-Baylis-Hillman反応 / スプレーイオン化 / 反応メカニズム / 連続送液システム / スルホンアミド / 反応解析デバイス / CSI-MS / building block / asymmetric synthesis / aldehyde / aziridine / guanidinium ylide / chiral catalyst / guanidine / β-ラクタム / ネーバー反応 / キラル / 還元的開裂 / 環開裂 / エポキシド / 反応機構 / キラルグアニジン / スフィンゴシン / ビニルアルデヒド / グアニジニウム塩 / ビルディングブロック / 不斉合成 / アルデヒド / アジリジン / グアニジニウムイリド / キラル触媒 / グアニジン / LPS / gangliosides / Haemophilus influenzae / Guillain-Barre syndrome / インフルエンザ / 神経内科学 / 神経免疫学 / 末梢神経 / インフルエンザ桿菌 / リポ多糖 / 糖脂質 / ヘモフィルス・インフルエンザ / ギラン・バレー症候群 / ionization / electrospray / hydrogen bonding / nucleoside / cluster ion / cold-spray / 非共有性相互作用 / クラスターイオン / 生体分子 / コールドスプレーイオン化 / ヌクレオシド / イオン化 / エレクトロスプレー / 水素結合 / ヌクレオチド / クラスターイオン化 / 複合材料・物性 / ディスプレイ / ナノ材料 / 有機導体 / 透明導電材料 Less

Structural analysis and dynamics of oligosaccharides by NMR Spectroscopy and Mass SpectrometryPrincipal Investigator
- Principal Investigator
  
  SEKI Hiroko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Study on spontaneously-formed transparent conducting organic/inorganic nanocomposite materials
- Principal Investigator
  
  HOSHINO Katsuyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Element strategy
- Research Institution
  Chiba University
溶液・固体NMR法によるイオン液体の構造解明Principal Investigator
- Principal Investigator
  
  関宏子
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
Molecular Structure Analysis on the Interactive Relations of Functionalized Compounds with NMR in Solution and Solid StatesPrincipal Investigator
- Principal Investigator
  
  SEKI Hiroko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
コールドスプレー質量分析およびNMR法によるイオン液体の溶液動態の構造解明Principal Investigator
- Principal Investigator
  
  関宏子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
Obsevation of ordered biomolecules in solution by using CSI-MS
- Principal Investigator
  
  YAMAGUCHI Kentaro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokushima Bunri University
Molecular-reorientational dynamics investigation of biomolecules in solution by NMR, X-ray and CSI-MS.Principal Investigator
- Principal Investigator
  
  SEKI Hiroko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
New Guanidine Chemistry
- Principal Investigator
  
  ISHIKAWA Tsutomu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Structural investigation of aggregates in various functional complexes, polymers and biomolecules hi solution by using PFG-NMR analysis.Principal Investigator
- Principal Investigator
  
  SEKI Hiroko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Development of cold-spray ionization mass spectrometry and its application to supramolecules and biomolecules
- Principal Investigator
  
  YAMAGUCHI Kentaro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University
The features of saccharides on the LPS of Hemophilus influenzae which elicits Guillain-Barre syndrome
- Principal Investigator
  
  HATTORI Takamichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  CHIBA UNIVERSITY

All 2013 2012 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Degradation Index for Quality Evaluation of Commercial Dietary Supplements of Bilberry Extract2013
- Author(s)
  Masao Yamamoto, Katsunori Yamaura, Makiko Ishiwatari, Maki Shimada, Sayaka Kado, Hiroko Seki, Norimoto Shimada, and Koichi Ueno
- Journal Title
  
  Journal of Food Science
  
  Volume: 78 Issue: 3 Pages: 477-483
- DOI
  10.1111/1750-3841.12043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590001, KAKENHI-PROJECT-24590723
[Journal Article] Ultraslow Dynamics at Crystallization of a Room-Temperature Ionic Liquid, 1-Butyl-3-methylimidazolium Bromid2012
- Author(s)
  Mamoru Imanari, Kozo Fujii, Takatsugu Endo, Hiroko Seki, Ken-ichi Tozaki, and Keiko Nishikawa
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 116 Pages: 3991-3997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590001
[Journal Article] Structural analyses of mannose pentasaccharide of high mannose type oligosaccharides by 1D and 2D NMR spectroscopy2012
- Author(s)
  Y. Kubota, H. Hori, R. Sawa, H. Seki and J. Uzawa
- Journal Title
  
  Magn. Reson. Chem.
  
  Volume: 50 Pages: 659-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590001
[Journal Article] NMR Study of Cation Dynamics in Three Crystalline States of 1-Butyl-3-methyl- imidazolium Hexafluorophosphate Exhibiting Crystal Polymorphis2012
- Author(s)
  Takatsugu Endo, Hiroki Murata, Mamoru Imanari, Noriko Mizushima, Hiroko Seki, and Keiko Nishikawa
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 116 Pages: 3780-3788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590001
[Journal Article] Ultraslow Dynamics at Crystallization of a Room-Temperature Ionic Liquid, 1-Butyl-3- methylimidazolium Bromide.2012
- Author(s)
  M. Imanari, K. Fujii, T. Endo, H. Seki, K. Tozaki,K. Nishikawa
- Journal Title
  
  J. Phys. Chem.
  
  Volume: B116 Issue: 13 Pages: 3991-3997
- DOI
  10.1021/jp300722j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21245003, KAKENHI-PROJECT-22590001, KAKENHI-PROJECT-24300265, KAKENHI-PROJECT-24655003
[Journal Article] NMR Study of Cation Dynamics in Three Crystalline States of Butyl-3-Methylimidazolium Hexafluorophosphate Exhibiting Crystal Polymorphism.2012
- Author(s)
  T. Endo, H. Murata, M. Imanari, N. Mizushima, H. Seki, K. Nishikawa
- Journal Title
  
  J. Phys. Chem.
  
  Volume: B116 Issue: 12 Pages: 3780-3788
- DOI
  10.1021/jp300636s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21245003, KAKENHI-PROJECT-22590001, KAKENHI-PROJECT-24655003
[Journal Article] The Characterization of Various o-Bisguanidinobenzene-Benzoic Acid Complexes in Solid And in Solution States2010
- Author(s)
  Kumamoto, T. Seki, H
- Journal Title
  
  Heterocycles 80巻
- NAID
  40016900107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590002
[Journal Article] NMR study on a novel mucin from jellyfish in natural abundance, qniumucin from Aurelia aurita2009
- Author(s)
  Uzawa, J., Urai, M., Baba, T., Seki, H., Taniguchi, K., Ushida, K
- Journal Title
  
  J.Nat.Prod. 72巻
  
  Pages: 818-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590002
[Journal Article] Complexability of o-Bisguanidino- benzenes with Arsenic and Phosphoric Acids in Solution and Solid States,and the Potential Use of their Immobilized Derivatives as Solid Base Ligands for Metal Salts and Arsenic Acid2009
- Author(s)
  Ito, T., Suda, K., Kumamoto, T., Nakanishi, W., Watanabe, T. Ishikawa, T. Seki, H. Kawahata, M. Yamaguchi, K. Ogura, Y. Kazuo T. Suzuki
- Journal Title
  
  Molecular Diversity
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590002
[Journal Article] Total synthesis of (±)-methyl-kinamycin C2007
- Author(s)
  T. Kumamoto, Y. Kitani, H. Tsuchiya, K.Yamaguchi, H. Seki, T. Ishikawa
- Journal Title
  
  Tetrahedron 63巻
  
  Pages: 5189-5199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590002
[Journal Article] Absolute Ordered Cluster Formation of an o-Bisguanidinobenzene - Benzoic Acid Complexes2006
- Author(s)
  Kawahata, M., Shikii, K., Seki, H., Ishikawa, T., Yamaguchi, K.
- Journal Title
  
  Chem.Pharm.Bull. 54
  
  Pages: 147-148
- NAID
  110004820346
- Data Source
  KAKENHI-PROJECT-17390008
[Journal Article] Observation of Water Molecules Bound to a Protein Using Cold-Spray Ionization Mass Spectrometry2005
- Author(s)
  Sei, Y., Shimotakahara, S., Ishii, J., Shindo, H., Seki, H., Yamaguchi, K., Tashiro, M.
- Journal Title
  
  Anal.Sci. 21
  
  Pages: 449-451
- NAID
  10015513763
- Data Source
  KAKENHI-PROJECT-17390008
[Journal Article] Intermolecular Hydrogen Bonding of Steroid Compounds : PFG NMR Diffusion Study, Cold-Spray Ionization(CSI)-MS and X-ray Analysis2005
- Author(s)
  Shikii, K., Seki, H., Sakamoto, S., Sei, Y., Utsumi, H., Yamaguchi, K.
- Journal Title
  
  Chem.Pharm.Bull. 53
  
  Pages: 792-795
- NAID
  10016655065
- Data Source
  KAKENHI-PROJECT-17390008
[Journal Article] Application of Difference NOE-pumping NMR Technique and Cold-Spray Ionization Mass Spectrometry to Identify a Ligand Binding with a Protein Receptor2004
- Author(s)
  H.Seki
- Journal Title
  
  Anal. Sci., 20
  
  Pages: 1467-1470
- NAID
  10013657686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590002
[Journal Article] Application of Difference NOE-pumping NMR Technique and Cold-Spray Ionization Mass Spectrometry to Identify a Ligand Binding with a Protein Receptor2004
- Author(s)
  H.Seki
- Journal Title
  
  Anal.Sci. 20
  
  Pages: 1467-1470
- NAID
  10013657686
- Data Source
  KAKENHI-PROJECT-16590002
[Journal Article] Application of Difference NOE-pumping NMR Technique and Cold-Spray Ionization Mass Spectrometry to Identify aLigand Binding with a Protein Receptor2004
- Author(s)
  H.Seki
- Journal Title
  
  Anal. Sci. 20
  
  Pages: 1467-1470
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590002
[Presentation] [C_4mim]^+カチオンを含むイオン液体の遅い相転移2010
- Author(s)
  関宏子
- Organizer
  第2回イオン液体全体会議
- Place of Presentation
  千葉
- Year and Date
  2010-01-19
- Data Source
  KAKENHI-PROJECT-20031006
[Presentation] ^1H NMR分光法によるイミダゾール系イオン液体の相転移に伴うカチオンのダイナミクス2010
- Author(s)
  関宏子
- Organizer
  第77回日本分析化学会有機微量分析研究懇談会・第83回計測自動制御学会力学量計測部会第・27回合同シンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22590001
[Presentation] 常磁性イオン液体の^<13>C-NMRによるアニオンーカチオン相互作用の研究2010
- Author(s)
  関宏子
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20031006
[Presentation] NMR study on influence of alkyl-chain length in phase transition of 1-alkvl-3- methylimidazolium bromide2009
- Author(s)
  Hiroko Seki
- Organizer
  The 50^<th> ENC
- Place of Presentation
  Asilomar, California
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-20031006
[Presentation] ビスグアニジン型化合物の金属カチオンとの親和性:環境浄化試薬開発を指向した金属塩補足の評価2008
- Author(s)
  関宏子
- Organizer
  第75回日本分析化学会有機微量分析研究懇談会・第77回計測自動制御学会力学量計測部会・第25回合同シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19590002
[Presentation] 常磁性イオン液体bmimFeCl_4の^<13>CNMRによる構造解明2008
- Author(s)
  関宏子
- Organizer
  文部科学省科学研究費補助金特定領域研究「イオン液体の科学1平成20年度第2回公開シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20031006
[Presentation] ビスグアニジン型化合物の金属カチオンとの親和性 : 環境浄化試薬開発を指向した金属塩補足の評価2008
- Author(s)
  関宏子
- Organizer
  第75回日本分析化学会有機微量分析研究懇談会・第77回計測自動制御学会力学量計測部会第・25回合同シンポジウム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19590002
[Presentation] ^<1>H NMR Study on Reorientational Dynamics of Ionic Liquid, 1-Butyl-3-metylimidazolium bromide, Accompanied with Phase Transitions2008
- Author(s)
  Hiroko Seki
- Organizer
  49th ENC
- Place of Presentation
  USA
- Year and Date
  2008-03-10
- Data Source
  KAKENHI-PROJECT-18045006
[Presentation] イオン液体〔bmim〕Xの動態構造について2007
- Author(s)
  関宏子
- Organizer
  「イオン液体の科学」平成19年度第2回公開シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2007-12-26
- Data Source
  KAKENHI-PROJECT-18045006
[Presentation] Molecular reorientational dynamics of 1-butyl-3-methylimidazolium halide by ^<13>C NMR focusing on the phase transition2007
- Author(s)
  H. Seki
- Organizer
  International Symposium on Structures and Dynamics of Ionic Liquids
- Place of Presentation
  横浜
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18045006

1. KUMAMOTO Takuya (50292678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. YAMAGUCHI Kentaro (50159208)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. HOSHINO Katsuyoshi (50192737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YOSHIDA Sayaka (10568439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. HATTORI Takamichi (30114317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NODA Kimitoshi (60164703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KUWABARA Satoshi (70282481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORI Masahiro (70345023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIKAWA Tsutomu (20114233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WATANABE Toshiko (40120323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. DANJYO Hiroshi (70332567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SEI Yoshihisa (40389177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 中越雅道 (40377114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小林稔 (50389178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 東崎健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 西川恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SEKI Hiroko 関 宏子

Research Projects

Research Products

Co-Researchers

Structural analysis and dynamics of oligosaccharides by NMR Spectroscopy and Mass SpectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on spontaneously-formed transparent conducting organic/inorganic nanocomposite materials

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

溶液・固体NMR法によるイオン液体の構造解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular Structure Analysis on the Interactive Relations of Functionalized Compounds with NMR in Solution and Solid StatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

コールドスプレー質量分析およびNMR法によるイオン液体の溶液動態の構造解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Obsevation of ordered biomolecules in solution by using CSI-MS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular-reorientational dynamics investigation of biomolecules in solution by NMR, X-ray and CSI-MS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Guanidine Chemistry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural investigation of aggregates in various functional complexes, polymers and biomolecules hi solution by using PFG-NMR analysis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cold-spray ionization mass spectrometry and its application to supramolecules and biomolecules

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The features of saccharides on the LPS of Hemophilus influenzae which elicits Guillain-Barre syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Degradation Index for Quality Evaluation of Commercial Dietary Supplements of Bilberry Extract2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ultraslow Dynamics at Crystallization of a Room-Temperature Ionic Liquid, 1-Butyl-3-methylimidazolium Bromid2012

Author(s)

Journal Title

Data Source

[Journal Article] Structural analyses of mannose pentasaccharide of high mannose type oligosaccharides by 1D and 2D NMR spectroscopy2012

SEKI Hiroko 関宏子