SAITO Haruo 斎藤春雄

Researcher Number	60114485
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2001 – 2014: 東京大学, 医科学研究所, 教授 2002: 東大, 医科学研究所, 教授
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Cell biology / Functional biochemistry
Keywords	Principal Investigator MAPキナーゼ / 酵母 / ストレス応答 / 細胞内シグナル伝達 / 細胞生物学 / 分子生物学 / シグナル伝達 / ヒト培養細胞 / stress / intracellular signal transduction … More / enzyme / environment / gene / ストレス / 酵素 / 環境 / 遺伝子 / MAP kinase / budding yeast / human cultured cells / stress response / signal transduction / ４回膜タンパク質 / 膜タンパク質 / 浸透圧応答 / Membrane protein / Osmoregulation / Yeast / Signal transduction / 浸透圧センサー Less

The mechanism of osmo-regulatory signal transduction by interactions among membrane proteins through their TM regionsPrincipal Investigator
- Principal Investigator
  
  SAITO Haruo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Osmoregulatory MAP kinase signal transduction pathwayPrincipal Investigator
- Principal Investigator
  
  SAITO Haruo
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Regulatory Mechanism of Stress-Responsive Signal Transduction PathwayPrincipal Investigator
- Principal Investigator
  
  SAITO Haruo
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Regulatory Mechanism of Stress-Responsive Signal Transduction Pathway in Human and Yeast CellsPrincipal Investigator
- Principal Investigator
  
  SAITO Haruo
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Regulatory mechanisms of the environmental stress-responsive MAP kinase signal pathwayPrincipal Investigator
- Principal Investigator
  
  SAITO Haruo
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
環境ストレス応答MAPキナーゼ経路活性化機構の研究Principal Investigator
- Principal Investigator
  
  斎藤春雄
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

[Journal Article] Osmosensing and scaffolding functions of the oligomeric four-transmembrane domain osmosensor Sho1.2015
- Author(s)
  Tatebayashi K, Yamamoto K, Nagoya M, Takayama T, Nishimura A, Sakurai M, Momma T, and Saito H.
- Journal Title
  
  Nature Communications
  
  Volume: 6 Issue: 1 Pages: 6975-6975
- DOI
  10.1038/ncomms7975
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24247034, KAKENHI-PROJECT-25440042, KAKENHI-PROJECT-24370053
[Journal Article] MCRIP1, an ERK substrate, mediates ERK-induced epigenetic gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP2015
- Author(s)
  Kenji Ichikawa, Yuji Kubota, Takanori Nakamura, Jane S. Weng, Taichiro Tomida, Haruo Saito and Mutsuhiro Takekawa
- Journal Title
  
  Molecular Cell
  
  Volume: 58 Issue: 1 Pages: 35-46
- DOI
  10.1016/j.molcel.2015.01.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117003, KAKENHI-PROJECT-24247034, KAKENHI-PROJECT-24390079, KAKENHI-PROJECT-25440043, KAKENHI-PROJECT-25650003, KAKENHI-PROJECT-15K19003, KAKENHI-PUBLICLY-15H01205, KAKENHI-PROJECT-15H04703, KAKENHI-PROJECT-15J07710
[Journal Article] Yeast osmosensors Hkr1 and Msb2 activate the Hog1 MAPK cascade by different mechanisms2014
- Author(s)
  K. Tanaka, K. Tatebayashi, A. Nishimura, K. Yamamoto, H.Y. Yang, and H. Saito
- Journal Title
  
  Science Signaling
  
  Volume: 7 Issue: 314 Pages: 1-10
- DOI
  10.1126/scisignal.2004780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24247034, KAKENHI-PROJECT-24370053, KAKENHI-PROJECT-25440042
[Journal Article] SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress.2013
- Author(s)
  Nakamura, T.
- Journal Title
  
  Nature Commun.
  
  Volume: 4 Issue: 1 Pages: 1775-1775
- DOI
  10.1038/ncomms2752
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117003, KAKENHI-PROJECT-24247034, KAKENHI-PROJECT-24390079, KAKENHI-PROJECT-25893039
[Journal Article] The temporal pattern of stimulation determines the extent and duration of MAPK activation in a Caenorhabditis elegans sensory neuron2012
- Author(s)
  Tomida, T., Oda, S., Takekawa, M., Iino, Y., and Saito, H
- Journal Title
  
  Sci Signal
  
  Volume: 5 Issue: 246 Pages: 76-76
- DOI
  10.1126/scisignal.2002983
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20115002, KAKENHI-PROJECT-23770141, KAKENHI-PROJECT-24247034, KAKENHI-PROJECT-24390079, KAKENHI-PLANNED-22117003, KAKENHI-PUBLICLY-23115706
[Journal Article] Response to hyperosmotic stress2012
- Author(s)
  H. Saito and F. Posas
- Journal Title
  
  Genetics
  
  Volume: 192 Issue: 2 Pages: 289-318
- DOI
  10.1534/genetics.112.140863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24247034
[Journal Article] Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation2011
- Author(s)
  Kubota Y, O' Grady P, Saito H, and Takekawa M
- Journal Title
  
  Nature Cell Biol
  
  Volume: 13 Pages: 282-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Regulation of cross-talk inyeast MAPK signaling pathways2010
- Author(s)
  Saito H
- Journal Title
  
  Curr Opin Microbiol
  
  Volume: 13 Pages: 677-683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Regulation of cross-talk in yeast MAPK signaling pathways2010
- Author(s)
  Haruo Saito
- Journal Title
  
  Current Opinion in Microbiology
  
  Volume: 13 Pages: 677-683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Dynamic control of yeast MAP kinase network by induced association and dissociation between the Ste50 scaffold and the Opy2 membrane anchor2010
- Author(s)
  Yamamoto K, Tatebayashi K, Tanaka K, and Saito H
- Journal Title
  
  Molecular Cell
  
  Volume: 40 Pages: 87-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Glycosylation defects activate filamentous growthKss1 MAPK and inhibit osmoregulatory Hog1 MAPK2009
- Author(s)
  Yang HY, Tatebayashi K, Yamamoto K, and Saito H
- Journal Title
  
  EMBO J
  
  Volume: 28 Pages: 1380-1391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Glycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK2009
- Author(s)
  Yang, H.-Y., Tatebayashi, K., Yamamoto, K., Saito, H.
- Journal Title
  
  EMBO J. 28
  
  Pages: 1380-1391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Stimulus-specific distinctions in spatial and emporal dynamics of stressactivated protein kinase kinase kinases revealed by a fluorescence resonance energy transfer biosensor2009
- Author(s)
  Tomida T, Takekawa M, O' Grady P, and Saito H
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 29 Pages: 6117-6127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Stimulus-specific distinctions in spatial and temporal dynamics of stress-activated protein kinase kinase kinases revealed by a fluorescence response energy transfer biosensor2009
- Author(s)
  Tomida, T., Takekawa, M., O'Grady, P., Saito, H.
- Journal Title
  
  Mol.Cell.Biol. 29
  
  Pages: 6117-6127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways2008
- Author(s)
  Arimoto, K., Fukuda, H., Imajo-Ohmi, S., Saito, H., Takekawa, M.
- Journal Title
  
  Nature Cell Biol. 10
  
  Pages: 1324-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Two adjacent docing sites in the yeast Hog1 mitogen-activated protein(MAP) kinase differentially interact with the Pbs2 MAP kinase kinase and the Ptp2 protein tyrosine phosphatase2008
- Author(s)
  Murakami Y, Tatebayashi K, and Saito H
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 28 Pages: 2481-2494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways2008
- Author(s)
  Arimoto K, Fukuda H, Imajo-Ohmi S, Saito H, and Takekawa M
- Journal Title
  
  Nature Cell Biol
  
  Volume: 10 Pages: 1324-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Phosphorylated Ssk1 prevents unphosphorylated Ssk1 from activating the Ssk2 mitogen-activated protein kinase kinase kinase in the yeast high-osmolarity glycerol osmoregulatory pathway2008
- Author(s)
  Horie T, Tatebayashi K, Yamada R, and Saito H
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 28 Pages: 5172-5183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kianse domain2007
- Author(s)
  Miyake Z, Takekawa M., Ge Q, andSaito H
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 27 Pages: 2765-2776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway2007
- Author(s)
  Tatebayashi, K., Tanaka, K., Yang, H.-Y., Yamamoto, K., Matsushita, Y., Tomida, T., Imai, M., Saito, H.
- Journal Title
  
  EMBO J. 26
  
  Pages: 3521-3533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Activation of MTK1/MEICK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain.2007
- Author(s)
  Miyake, Z., Takekawa, M., Ge, Q., Saito, H.
- Journal Title
  
  Molecular and Cellular Biology 27
  
  Pages: 2765-2776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Transmembrane mucinsHkr1andMsb2areputativeosmosensorsinthe SHO1 branch of yeast HOG pathway.2007
- Author(s)
  Tatebayashi, K., Tanaka, K., Yang, H. -Y., Yamamoto, K., Matsushita, Y., Tomida, T., Imai, M., Saito, H.
- Journal Title
  
  EMBO J. 26
  
  Pages: 3521-3533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway.2007
- Author(s)
  Tatebayashi, K., Tanaka, K., Yang, H. -Y., Yamamoto, K., Matsushita, Y., Tomida, T., Imai, M., ^*Saito, H.
- Journal Title
  
  EMBO J. 26
  
  Pages: 3521-3533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway2007
- Author(s)
  Tatebayashi K, Tanaka K, Yang HY, Yamamoto K, Matsushita Y, Tomida T, Imai M, and Saito H
- Journal Title
  
  EMB J
  
  Volume: 26 Pages: 3521-3533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Journal Article] Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain.2007
- Author(s)
  Miyake, Z., Takekawa, M., Ge, Q., Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 2765-2776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain.2007
- Author(s)
  Miyake, Z., Takekawa, M., Ge, Q., ^*Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 2765-2776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Transmembrane mucins Hkrl and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway.2007
- Author(s)
  Tatebayashi, K., Tanaka, K., Yang, H.-Y., Yamamoto, K., Matsushita, Y., Tomsida, T., Imai, M., Saito, H.
- Journal Title
  
  The EMBO Journal 26
  
  Pages: 3521-3533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Adaptor functions of Cdc42, Ste50, and Shol in the yeast osmoregulatory HOG MAPK pathway.2006
- Author(s)
  Tatebayashi, K., Yamamoto, K., Tanaka, K., Tomida, T., Maruoka, T., Kasukawa, E., Saito, H.
- Journal Title
  
  The EMBO Journal 25
  
  Pages: 3033-3044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway.2006
- Author(s)
  Tatebayashi, K., Yamamoto, K., Tanaka, K., Tomida, T., Maruoka, T., Kasukawa, E., Saito, H.
- Journal Title
  
  EMBO J. 25
  
  Pages: 3033-3044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway.2006
- Author(s)
  Tatebayashi, K., Yamamoto, K., Tanaka, K., Tomida, T., Maruoka, T., Kasukawa, E., ^*Saito, H.
- Journal Title
  
  EMBO J. 25
  
  Pages: 3033-3044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.2005
- Author(s)
  Takekawa, M., Tatebayashi, K., ^*Saito, H.
- Journal Title
  
  Mol. Cell 18
  
  Pages: 295-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.2005
- Author(s)
  Nam, H. -J., Poy, F., ^*Saito, H., Frederick, C.A.
- Journal Title
  
  J. Exp. Med. 201
  
  Pages: 441-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.2005
- Author(s)
  Takekawa, M., Tatebayashi, K., Saito, H.
- Journal Title
  
  Mol. Cell 18
  
  Pages: 295-306
- NAID
  10016687433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.2005
- Author(s)
  Takekawa, M., Tatebayashi, K., Saito, H.
- Journal Title
  
  Molecular Cell 18
  
  Pages: 295-306
- NAID
  10016687433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Dictyostelium discoideum requires an Alix/AIP1 homolog, DdAlix, for morphogenesis in alkaline environments.2005
- Author(s)
  Ohkouchi, S., Saito, H., Aruga, F., Maeda, T., Shibata, H., ^*Maki, M.
- Journal Title
  
  FEBS Lett. 579
  
  Pages: 1745-1750
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.2005
- Author(s)
  Nam, H.-J., Poy, F., Saito, H., Frederick, C. A.
- Journal Title
  
  Journal of Experimental Medicine 201
  
  Pages: 441-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.2005
- Author(s)
  Nam, H. -J., Poy, F., Saito, H., Frederick, C. A.
- Journal Title
  
  J. Exp. Med. 201
  
  Pages: 441-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 276-272
- NAID
  10016201785
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast.2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast.2004
- Author(s)
  Saito, H., Tatebayashi, K.
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  The Journal of Biochemistry 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast.2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 276-272
- NAID
  10016201785
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast.2004
- Author(s)
  Saito, H., Tatebayashi, K.
- Journal Title
  
  J. Biochem. (Tokyo) 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast.2004
- Author(s)
  ^*Saito, H., Tatebayashi, K.
- Journal Title
  
  J. Biochem. (Tokyo) 136
  
  Pages: 267-272
- NAID
  10016201785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Regulation of the osmoregulatory HOG MAPK cascade in yeast2004
- Author(s)
  Saito, Haruo
- Journal Title
  
  Journal of Biochemistry 136
  
  Pages: 276-272
- NAID
  10016201785
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] The Sln1-Ypol-Ssk1 multistep phosphorelay system that regulates an osmosensing MAP kinase cascade in yeast2003
- Author(s)
  Saito, Haruo
- Journal Title
  
  Histidine kinases in signal transduction, edited by Inouye, M., and Dutta, R., Academic Press, San Diego
  
  Pages: 397-419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] The Sln1-Ypd1-Ssk1 multistep phosphorelay system that regulates an osmosensing MAP kinase cascade in yeast.2003
- Author(s)
  Saito, H.
- Journal Title
  
  In Histidine kinases in signal transduction, (Inouye, M., & Dutta, R., Eds). Academic Press, San Diego.
  
  Pages: 397-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlar in vivo.2003
- Author(s)
  Krueger, N. X., Reddy, R. S., Johnson, K., Bateman, J., Kaufmann, N., Scalice, D., Van Vactor, D., ^*Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 23
  
  Pages: 6909-6921
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway.2003
- Author(s)
  Tatebayashi, K., Takekawa, M., ^*Saito, H.
- Journal Title
  
  EMBO J. 22
  
  Pages: 3624-3634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] The Slnl-Ypdl-Sskl multistep phosphorelay system that regulates an osmosensing MAP kinase cascade in yeast.2003
- Author(s)
  Saito, Haruo
- Journal Title
  
  “Histidine kinases in signal transduction, " edited by Inouye, M・, and Dutta, R., Academic Press, San Diego
  
  Pages: 397-419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Yeast osmosensor Sln1 and plant cytokininreceptor Cre1 respond to changes in turgor pressure.2003
- Author(s)
  Reiser, V., Raitt, D. C., Saito, H.
- Journal Title
  
  J. Cell Biol. 161
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] The Sln1-Ypd1-Ssk1 multistep phosphorelay system that regulates an osmosensing MAP kinase cascade in yeast.2003
- Author(s)
  Saito, Haruo
- Journal Title
  
  “Histidine kinases in signal transduction, "edited by Inouye, M., and Dutta, R., Academic Press, San Diego
  
  Pages: 397-419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlarinvivo.2003
- Author(s)
  Krueger, N. X., Reddy, R. S., Johnson, K., Bateman, J., Kaufmann, N., Scalice, D., Van Vactor, D., Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 23
  
  Pages: 6909-6921
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway.2003
- Author(s)
  Tatebayashi, K., Takekawa, M., Saito, H.
- Journal Title
  
  The EMBO Journal 22
  
  Pages: 3624-3634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104021
[Journal Article] Yeast osmosensor Sln1 and plant cytokinin receptor Cre1 respond to changes in turgor pressure.2003
- Author(s)
  Reiser, V., Raitt, D. C., ^*Saito, H.
- Journal Title
  
  J. Cell Biol. 161
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway.2003
- Author(s)
  Tatebayashi, K., Takekawa, M., Saito, H.
- Journal Title
  
  EMBO J. 22
  
  Pages: 3624-3634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] The Sln1-Ypd1-Ssk1 multistep phosphorelay system that regulates an osmosensing MAP kinase cascade in yeast.2003
- Author(s)
  ^*Saito, H.
- Journal Title
  
  In Histidine kinases in signal transduction, ((Inouye, M., & Dutta, R., Eds). Academic Press, San Diego. )
  
  Pages: 397-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Regulation of MTK1/MEKK4 kinase activity by its N-terminal domain and GADD45 binding.2002
- Author(s)
  Mita, H., Tsutsui, J., Takekawa, M., Witten, E. A., ^*Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 22
  
  Pages: 4544-4555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Smad-dependent GADD45b expression mediates delayed activation of p38 MAP kinase by TGF-b.2002
- Author(s)
  Takekawa, M., Tatebayashi, K., Itoh, F., Adachi, M., Imai, K., Saito, H.
- Journal Title
  
  EMBO J. 21
  
  Pages: 6473-6482
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Smad-dependent GADD45b expression mediates delayed activation of p38 MAP kinase by TGF-b.2002
- Author(s)
  Takekawa, M., Tatebayashi, K., Itoh, F., Adachi, M., Imai, K., ^*Saito, H.
- Journal Title
  
  EMBO J. 21
  
  Pages: 6473-6482
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Regulation of MTK1/MEKK4 kinase activity by its N-terminal domain and GADD45 binding.2002
- Author(s)
  Mita, H., Tsutsui, J., Takekawa, M., Witten, E. A., Saito, H.
- Journal Title
  
  Mol. Cell. Biol. 22
  
  Pages: 4544-4555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.2002
- Author(s)
  Tsujikawa, K., Ichijo, T., Moriyama, K., Tadotsu, N., Sakamoto, K., Sakane, N., Fukada, S., Furukawa, T., Saito, H., Yamamoto, H.
- Journal Title
  
  Mol. Cancer Res. 1
  
  Pages: 155-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086202
[Journal Article] Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.2002
- Author(s)
  Tsujikawa, K., Ichijo, T., Moriyama, K., Tadotsu, N., Sakamoto, K., Sakane, N., Fukada, S., Furukawa, T., Saito, H., ^*Yamamoto, H.
- Journal Title
  
  Mol. Cancer Res. 1
  
  Pages: 155-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086101
[Journal Article] Response to hyperosmotic stress
- Author(s)
  Saito H, and Posas F
- Journal Title
  
  Genetics
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Dynamic regulation of hyperosmotic stress response in the budding yeast2011
- Author(s)
  斎藤春雄
- Organizer
  Society of General Microbiology Conference
- Place of Presentation
  Harrogate, UK
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Dynamic regulation of hyperosmotic stress response in the budding yeast2011
- Author(s)
  Haruo Saito
- Organizer
  Society for General Microbiology Conference 2011
- Place of Presentation
  Harrogate, UK
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Osmosensory signal transduction inbudding yeast2010
- Author(s)
  斎藤春雄
- Organizer
  Gordon Research Conference on "Sensory Transduction in Microorganisms."
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2010-01-27
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Osmosensory signal transduction in budding yeast2010
- Author(s)
  Haruo Saito
- Organizer
  Gordon Research Conference on"Sensory Transduction in Microorganims."
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2010-01-27
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Signal transduction pathways2010
- Author(s)
  斎藤春雄
- Organizer
  Analysis and Engineering of Biomolecular Systems
- Place of Presentation
  Spetses, Greece
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Regulation of the osmoadaptive HOG MAPK pathway in the budding yeast2009
- Author(s)
  斎藤春雄
- Organizer
  Marie Curie Research & Training Network Meeting on "MAPK Signalling during Fungal Pathogenesis"
- Place of Presentation
  Berlin, Germa
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Regulation of the osmoadaptive HOG MAPK pathway in the budding yeast2009
- Author(s)
  Haruo Saito
- Organizer
  Marie Curie Research & Training Network Meeting on"MAPK Signalling during Fungal Pathogenesis."
- Place of Presentation
  Berlin, Germany
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Regulation of stress MAPK pathways in mammalian and yeast cells2008
- Author(s)
  斎藤春雄
- Organizer
  OIST国際ワークショップ
- Place of Presentation
  沖縄県国頭郡恩納
- Year and Date
  2008-03-10
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Regulation of stress MAPK pathways in mammalian and yeastcells2008
- Author(s)
  斎藤春雄
- Organizer
  OIST(沖縄科学技術研究基盤整備機構)国際ワークショップ「Systems Biology on MAPK Pathways Workshop」
- Place of Presentation
  沖縄県国頭郡恩納
- Year and Date
  2008-03-10
- Data Source
  KAKENHI-PROJECT-19107004
[Presentation] Dynamic regulation of hyperosmotic stress signaling in the budding yeast
- Author(s)
  H. Saito
- Organizer
  第２２回　国際生化学・分子生物学会議
- Place of Presentation
  スペイン　セビリア
- Invited
- Data Source
  KAKENHI-PROJECT-24247034
[Presentation] Role of membrane proteins in osmoregulatory signal transduction in yeast
- Author(s)
  H. Saito
- Organizer
  PRBB会議
- Place of Presentation
  スペイン　バルセロナ
- Invited
- Data Source
  KAKENHI-PROJECT-24247034

1. 舘林和夫 (50272498)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. 武川睦寛 (30322332)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. YOSHIOKA Katsuji (60200937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MAEDA Tatsuya (90280627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 西田栄介 (60143369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 秋山徹 (70150745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 野澤義則 (10021362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ICHIKAWA Kazuhisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 飯野雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO Haruo 斎藤 春雄

Research Projects

Research Products

Co-Researchers

The mechanism of osmo-regulatory signal transduction by interactions among membrane proteins through their TM regionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Osmoregulatory MAP kinase signal transduction pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory Mechanism of Stress-Responsive Signal Transduction PathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory Mechanism of Stress-Responsive Signal Transduction Pathway in Human and Yeast CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanisms of the environmental stress-responsive MAP kinase signal pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

環境ストレス応答MAPキナーゼ経路活性化機構の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Osmosensing and scaffolding functions of the oligomeric four-transmembrane domain osmosensor Sho1.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MCRIP1, an ERK substrate, mediates ERK-induced epigenetic gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Yeast osmosensors Hkr1 and Msb2 activate the Hog1 MAPK cascade by different mechanisms2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The temporal pattern of stimulation determines the extent and duration of MAPK activation in a Caenorhabditis elegans sensory neuron2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response to hyperosmotic stress2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation2011

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of cross-talk inyeast MAPK signaling pathways2010

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of cross-talk in yeast MAPK signaling pathways2010

Author(s)

SAITO Haruo 斎藤春雄