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BEPPU Masatoshi  別府 正敏

ORCIDConnect your ORCID iD *help
Researcher Number 60114633
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2006 – 2008: 東京薬科大学, 薬学部, 教授
1997 – 2003: 東京薬科大学, 薬学部, 教授
1995 – 1996: 東京薬科大学, 薬学部, 助教授
1986: Tokyo College of Pharmacy, 薬学部, 講師
Review Section/Research Field
Principal Investigator
Biological pharmacy / Environmental pharmacy / Biological pharmacy
Except Principal Investigator
Radiation science / Environmental pharmacy / Biological pharmacy / Biological pharmacy
Keywords
Principal Investigator
アポトーシス / マクロファージ / 酸化ストレス / CD43 / 糖鎖認識 / 生体防御 / 細胞認識 / Oxidative stress / Host defense / Cell recognition … More / ACPH / レクチン / 環境化学物質 / 内分泌撹乱化学物質 / 環境ホルモン / 細胞毒性指標 / 細胞死 / タンパク質リン酸化 / シグナル伝達撹乱 / アポトーシス撹乱 / ミクログリア / 死細胞除去 / シャトルタンパク質 / 動脈硬化 / ヌクレオリン / スカベンジャーレセプター / ベータアミロイド / 酸化的ストレス / マクロファージレクチン / 細胞傷害 / ポリラクトサミン糖鎖 / 老化赤血球 / アポトーシス細胞 / 老化細胞 / macrophage lectin / Cell damage / Polylactosamine / Aged erythrocyte / Apoptotic cell / プロテアーゼ / セリンプロテアーゼ / タンパク質分解 / 赤血球プロテアーゼ / グリーケーション / 酸化タンパク質 / グリケーション / Protease / Serine protease / Proteolysis / Erythrocyte protease / Glycation / Oxidized protein / 細胞接着 / macrophage / lectin / oxidative stress / apoptosis / carbohydrate recognition / cell recognition / host defense / 貪食 / Macrophage / Apoptosis / Carbohydrate recognition / Phagocytosis … More
Except Principal Investigator
MUC1 / Radiation / GFP / Tumor antigen / MUCl / 放射線 / 腫瘍抗原 / 放射線応答 / ムチン / X線 / Tumor anitigen / マクロファージ / 内分泌撹乱化学物質 / 分化 / 内分泌攪乱化学物質 / macrophage / endocrine disrupting chemicals / differentiation / ヌクレオリン / シャトルタンパク / タンパク質 / NUCLEOLIN / SHUTTLE PROTEIN / 赤血球 / 細胞膜 / 過酸化脂質 / 膜タンパク / 膜傷害 / アルデヒド / マロンアルデヒド / ケイ光 / Erythrocyte / Cell membrane / Lipid oxidation / Membrane damage / Membrane protein / Malonaldehyde / Aldehyde Less
  • Research Projects

    (10 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (6 People)
  •  STUDY ON THE FUNCTIONS OF CELL-SURFACE SHUTTLE PROTEIN NUCLEOLINPrincipal Investigator

    • Principal Investigator
      BEPPU Masatoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Studies of nucleolin, a shuttle protein between the nucleus, cytoplasm, and cell surface

    • Principal Investigator
      HIRANO Kazuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  化学物質の新たな毒性指標としてのアポトーシス撹乱作用Principal Investigator

    • Principal Investigator
      別府 正敏
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Molecular mechanisms of the carbohydrate-dependent recognition and clearance of apoptotic cells and oxidized cells by macrophages.Principal Investigator

    • Principal Investigator
      BEPPU Masatoshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  REAL-TIME DETECTION OF THE EFFECTS OF ENVIRONMENTAL STRESS TO CELLULAR IMMUNITY

    • Principal Investigator
      HIRANO Kazuya
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCE
  •  遺伝子発現を利用した照射効果測定

    • Principal Investigator
      HIRANO Kazuya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCE
      The University of Tokyo
  •  Structure and function of a lectin-like protein of macrophage cell membrane that recognizes oxidized cellsPrincipal Investigator

    • Principal Investigator
      BEPPU Masatoshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Structural and Functional Studies of a Protease That Preferentially Degrades Oxidized ProteinsPrincipal Investigator

    • Principal Investigator
      BEPPU Masatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Mechanism of Recognition of Cells Denatured by Oxidative StressPrincipal Investigator

    • Principal Investigator
      BEPPU Masatoshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Involvement of Lipid Oxidation Products in Erythrocyte Membrane Damage

    • Principal Investigator
      KIKUGAWA Kiyomi
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo College of Pharmacy

All 2009 2007

All Journal Article

  • [Journal Article] Clearance of oxidatively damaged cells by macrophages : Recognition of glycoprotein clusters by macrophage-surface nucleolin as early apoptotic cells2009

    • Author(s)
      Miki, Y., Itoh, T., Hirano, K., Eda, S., Hayashi, A., Yamanaka, M., and Beppu, M.
    • Journal Title

      Biol. Pharm. Bull. 32

      Pages: 564-572

    • NAID

      110007160701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590080
  • [Journal Article] Clearance of oxidized erythrocytes by macrophages : Involvement of caspases in the generation of clearance signal at band 3 glycoprotein2007

    • Author(s)
      Miki, Y., Tazawa, T., Hirano, K., Matsushima, H., Kumamoto, S, Hamasaki, N., Yamaguchi, T., and Beppu, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 363

      Pages: 57-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590080
  • 1.  HIRANO Kazuya (80251221)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 2.  MIKI Yuichi (20366420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  KIKUGAWA Kiyomi (90120146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SUZUKI Norio (10010050)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  林 明子 (20339097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  松本 義久 (20302672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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