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YAMAMOT Kenichi  山本 健一

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YAMAMOTO Ken-ichi  山本 健一

山本 健一  ヤマモト ケンイチ

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Researcher Number 60115285
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2006 – 2007: 金沢大学, がん研究所, 教授
1993 – 2002: 金沢大学, がん研究所, 教授
1995: 金沢大学がん研究所, 病態生理部, 教授
1986: 金沢大, がん研究所, 助手
Review Section/Research Field
Principal Investigator
Immunology / Biological Sciences / Pathological medical chemistry / Cell biology
Keywords
Principal Investigator
インヒビター / 蛋白分解 / 転写因子 / リン酸化 / 免疫抑制剤 / シグナル伝達 / p53 / NF-kB / NF-κB / 蛋白相互作用 … More / 細胞周期 / CDK / Rad51 / プロテアソーム / ユビキチン / アポトーシス / ATM / キネシン / Glivec / c-Abl / Arg / DNA損傷 / トリDT40細胞 / 遺伝子ノックアウト / ATR / ノックアウト / FKBP / プロテアゾーム / NF‐kB / ロイシンジッパー / 免疫制御 / 有害ストレス / Focus Formation / Self-Association / Tyrosine Phosohorvlation / Homoloaous Recombination / DNA Repair / Focus形成 / チロシン隣酸化 / Givec / focus形成 / self-association / チロシン燐酸化 / 相同組み替え / DNA修復 / RAD 17 / RAD 9 / RAD 51 / ARG / DNA DAMAGE / CHICKEN DT40 CELLS / GENE DISRUPTION / CELL CYCLE / Rad17 / Rad9 / Microtubules / Kinesin Superfamily / Proteolysis / NF-kappaB Inhibitors / NF-kappaB / Apoptosis / Growth / T Cells / Tリンパ球 / 遺伝子導入 / 血清アミロイドA遺伝子の発現誘導 / インターロイキンI / c-abl / 活性酵素 / 放射線 / ゲノム維持 / PI3キナーゼ / DT-40 / トリB細胞 / 免疫不全 / 細胞分裂 / スプライシング / 中心体分離 / キネシン様蛋白 / ユビキムン / 相互作用 / MAPK / MAPキナーゼ / Tax / HTLV-1 / Rel / 白血病 / サイトカイン / SH基 / 酸化還元 / 活性酸素 / レドックス機構 / 炎症 … More
Except Principal Investigator
Signal Transduction / ADF / AP-1 / REDUCTION / OXIDATIVE STRESS / REDOX / THIOREDOXIN / NFRB / Redox Regulation / チオレドキシン / レドックス制御 / プロモーター解析 / オキシゲン、バースト / 酸化ストレス / 白血病 / ノックアウトマウス / 胚形成 / Redox regulation / REDOX REGULATION / SIGNAL TRANSDUCTION Less
  • Research Projects

    (25 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (23 People)
  •  c-Abl regulates Rad51 chromatin associationPrincipal Investigator

    • Principal Investigator
      YAMAMOT Kenichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  ゲノム維持機構におけるATMファミリーの機能とその異常による発がん機構の解析Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  ROLES FOR VERTEBRATE ATM IN CELL CYCLE CHECKPOINT CONTROLPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Ken-ichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      KANAZAWA UNIVERSITY
  •  ゲノム維持機構におけるATMファミリーの機能とその異常による発がん機構の解析Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  細胞ストレス応答におけるプロテアソームの活性制御機構Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  シグナルモジュレーターとしてのFKBPシャペロンの役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  細胞ストレス応答におけるプロテアーゼの役割とその制御Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  ATMファミリーの異常による免疫不全の分子病態Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  シグナルモジュレーターとしてのFKBP分子シャペロンの役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  エイズ病態におけるNF-kB活性化とその制御機構Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  転写因子活性化におけるプロテアゾームの役割とその制御Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  シグナルモジュレーターとしてのFKBPシャペロンの役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  新しいキネシン様蛋白質のクローニングとその転写因子制御における役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  エイズにおけるNF-κBとp53の役割とその活性制御機構Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  転写因子活性化におけるプロテアーゼの役割とその制御Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  造血系の細胞の分化・増殖・アポトーシスにおけるNF-kBファミリーの役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  NF-kB活性化のシグナル伝達機構の解析とその阻害剤の開発Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  Redox Regulation and Cellular Signal Transduction

    • Principal Investigator
      YODOI Junji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  ストレス応答因子としてのNF-kBの活性化とその制御機構Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  有害ストレスによる細胞周期ブロックの分子機序の研究Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  NF-kB制御に関わるT細胞因子のクローニングとT-B細胞間相互作用における役割Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  Molecular cloning of a new kinesin superfamily member interacting with a NF-kappaB inhibitorPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Ken-ichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University
  •  ストレス応答因子としてのNF-κBの活性化機構とその制御Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  サイトカイン産生異常におけるNF-κB/Relの機能変化とその制御異常Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University
  •  インターロイキン1リセプターに対する単クローン抗体の作製と遺伝子工学への応用Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University

All 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] ATM, a paradigm for a stress-responsive signal transducer in higher vertebrate cells.2006

    • Author(s)
      Yamamoto, K., et. al.
    • Journal Title

      Subcell Biochem. 40

      Pages: 327-339

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Journal Article] ATM, a paradigm for a stress-responsive signal transducer in higher vertebrate cells2006

    • Author(s)
      Yamamoto, K., et. al.
    • Journal Title

      Subcell Biochem 40

      Pages: 327-339

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] Activation mechanisms for ATM kinase by oxidative stress2008

    • Author(s)
      Kobayashi, M., Yamamoto, K
    • Organizer
      International AT Workshop
    • Place of Presentation
      Otu, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] A critical role for NBS1 in DNA replication checkpoint activation2007

    • Author(s)
      Yamamoto K., et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      神奈川県(横浜市)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] ATM activation by a sulfhydryl-reactive cyclopentenone prostaglandin2007

    • Author(s)
      Kobayashi, M., Yamamoto, K
    • Organizer
      The 30th Annual Meeting of the Molecular Biology Society of Japan and The80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] Function of the Ran system genes for telomere silencing in budding yeast2007

    • Author(s)
      Hayashi, N., Nishimoto, T., Murakami, S., Yamamoto, K
    • Organizer
      The 30th Annual Meeting of the Molecular Biology Society of Japan and The80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] A role for Tyr-315 in Rad51 functions.2007

    • Author(s)
      Shimizu, H.,Yamamoto, K
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] Activation mechanisms for ATM checkpoint kinase by oxidative stress2007

    • Author(s)
      Kobayashi, M.,Yamamoto, K
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] A critical role for NBS1 in DNA replication checkpoint activation2007

    • Author(s)
      Yamamoto, K., Kobayashi, M., Shiotani, B., Wakabayashi, K
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] DNA損傷シグナリングにおけるDNA修復因子の機能解析2006

    • Author(s)
      Yamamoto K., et. al.
    • Organizer
      第65回日本癌学会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] A role for ATM in cellular oxidative stress response2006

    • Author(s)
      Kobayashi, M.,Yamamoto, K
    • Organizer
      65th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] A role for tyrosine phosphorylation in Rad51 focus formation2006

    • Author(s)
      Shimizu, H.,Yamamoto, K
    • Organizer
      65th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • [Presentation] Functional analysis of DNA repair factors in DNA damage signaling2006

    • Author(s)
      Yamamoto, K., Kobayashi, M., Shiotani, B., Wakabayashi, K
    • Organizer
      65thAnnual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590286
  • 1.  SHIMIZU Hiroko (20126585)
    # of Collaborated Projects: 22 results
    # of Collaborated Products: 0 results
  • 2.  中山 構造 (70192680)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIOKA Katuji (60200937)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  YODOI Junji (80108993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KUCHINO Yoshiyuki (60124418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TOYOKUNI Shinya (90252460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SABE Hisataka (40187282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  チェー ホーズン
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  パク サムチュル
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ストルツ ギゼラ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  カリン マイケル
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  チュルツ トーマス
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  CHAE Ho Zoon
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  PARK Sang Chul
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  STORZ Gisela
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KARIN Michael
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TURSZ Thomas
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  チュルソ トーマス
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  コルスマイヤー スタンレ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  チュルツ トマス
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  キン ユン
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  キャンビア ジョン
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  花房 秀三郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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