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MARUO Takeshi  丸尾 猛

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… Alternative Names

丸尾 毅  マルオ タケシ

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Researcher Number 60135811
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007: Kobe University, 大学院・医学系研究科, 教授
2005 – 2006: 神戸大学, 大学院医学系研究科, 教授
2001 – 2005: 神戸大学, 大学院・医学系研究科, 教授
1996 – 2003: 神戸大学, 医学部, 教授
1995: 神戸大学, 医学部, 助教授 … More
1994: Kobe University School of Medicine, Associate Professor, 医学部・付属病院, 助教授
1994: 神戸大学, 医学部・附属病院, 助教授
1991 – 1993: 神戸大学, 医学部, 講師
1986 – 1990: 神戸大学, 医学部附属病院, 講師
1987 – 1989: 神戸大学, 医学部付属病院, 講師
1988: 神戸大学, 医学部付属病院・産婦人科, 講師
1988: Kobe University School of Medicine,Assistane Professor, 医学部附属病院産科婦人科, 講師
1986: 神戸大, 医学部, 講師
1986: 神戸大学, 医学部, 講師
1986: Assistant Professor, Kobe University Hospital, 附属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences
Keywords
Principal Investigator
アポトーシス / 胎盤 / EGF / granulosa cell / apoptosis / 甲状腺ホルモン / placenta / ovary / 増殖 / トロホブラスト … More / Bcl-2 / A-kinase / PCNA / Fas / progesterone / TNFα / プロゲステロン / differentiation / proliferation / growth factor / 卵巣 / 分化 / 卵巣顆粒膜細胞 / trophoblast / IGF-I / 浸潤能 / 絨毛外トロホブラスト / 子宮筋腫 / 絨毛癌 / Fas ligand / C-kinase / cyclic AMP / hCG / cervical cancer / choriocarcinoma / Tropko blaso / myc oncogene product / EGF receptor / dibutyryl cAMP / Epidermal Grouth Factor(EGF) / 子宮頸部扁平上皮癌 / Epidermal Growth Factor(EGF) / TA-4 / 繊毛性ゴナドトロピン / 繊毛癌 / Cyclic AMP / PDGF / TA-4Euideral growth factor(EGF) / 絨毛性ゴナドトロピン、腫瘍関連拡原 / cyclicAMP / 腫瘍関連抗原 / 絨毛性ゴナドトロピン / 子宮癌 / invasive potential / thyroid hormone / extravillous trophoblast / マトリックスメタロプロテイナーゼ阻害因子 / フィブロネクチン / マトリックスメタロプロテイナーゼ / インテグリン / 細胞接着関連因子 / 初代分離培養細胞 / 細胞接着関連分子 / 胎盤形成 / leiomyoma cell / 絨毛外栄養膜細胞 / テロメラーゼ / CDDP / 子宮頚部扁平上皮 / 子宮内膜細胞 / IUS / レボノルゲストレル / adrenomedullin / 子宮筋腫細胞 / uterus / 女性生殖器細胞 / 子宮 / 細胞死(アポトーシス) / FSH / TGFβ / 卵胞閉鎖 / エストロゲン / アポト-ミス / 卵胞 / oncogene / 細胞成長因子 / 顆粒膜細胞 / 卵胞発育 / サイトカイン / 受容体 / 癌遺伝子 / 成長因子 / 胎盤人口ホブラスト / Thyroid Hormone Receptor / Differentiation / Follicular Growth / maturation / erb-A / Thyroid Hormone / Granulosa cell / Ovary / proqesterone / estrodiol / human chorionic gonaclafropin / granuloga cell / epidermal growth factor / eropaoblast / epidermal groweh factor / polycystic ovary / insulinーlike groweh faetor / dual action / epidermcl grorseh tactor / Prophoblast / granu losa cell / plaeereta / diffarenf,aficr / insulin / IcrF-I / ehyroid horrurio / encogene, / ep,dermal grorsdi / Placeuta / Ooaiy / 妊娠高血圧症候群 / ミオシン / アクチン / Progesterone receptor / 筋腫細胞 / J867 / CDB-2914 / SPRM / コラーゲン / 細胞外基質蛋白 / プロゲステロン受容体モデュレーター / LGR8 / LGR7 / リラキシン受容体 / 子宮頚部癌 / アドレノモデュリン / 黄体顆粒膜細胞 / Caski / JAr / 扁平上皮癌 / 子宮頸部癌 / アドレノモジュリン / Fas antigen … More
Except Principal Investigator
甲状腺ホルモン / 妊娠中毒症 / cytotrophoblast / 細胞内Na濃度 / 骨密度 / 妊娠高血圧症 / 顆粒膜細胞 / TSH / 5-deiodinase / 胎児仮死 / placenta / IUGR / Bcl-2蛋白 / トロホブラスト / 脱落膜 / 胎盤 / 増殖能 / アポトーシス / syncytiotrophoblast / Endothelin-1 / IGF-I / ダウンステージ / 術前化学療法 / 高用量化学療法 / 子宮頚癌 / Thyroid Hormone / Atrial Natriuretic Peptides, / Intracellular Sodium Concentration, / Intracellular Calcium Concentration, / Bone Mineral Density, / Pregnancy-induced Hypertension, / BeWo Cell Culture, / Intracellular Signal Transduction System, / 加令 / 肝細胞 / Ca / 加齢 / 骨代謝 / 細胞内ナトリウムイオン / 細胞内カルシウムイオン / 血小板 / 絨毛細胞機能 / 細胞成長因子 / 低エストロゲン / 腸管Ca吸収能 / エソドセリンー1 / 妊婦高血圧症 / hPL / 細胞内情報伝達系 / エンドセリンー1 / 心房性ナトリウム利尿ペプチド / 細胞内Ca濃度 / 培養絨毛癌(BeWo)細胞 / 細胞内刺激伝達系 / Granulosa Cell / Cell Culture / Functional Differentiation / sycytiotrophoblast / Human Placental Trophoblast / Nuclear Receptor / aromatization / steroidogenesis / 機能文化 / 核蛋白 / ヒト胎盤繊毛細胞 / 抗核レセプター抗体 / ブタ顆粒膜細胞 / ヒト胎盤絨毛細胞 / 核レセプター / 甲状線ホルモン / 細胞培養 / 機能分化 / ヒト胎盤絨毛 / 核レセプタ- / Latent Fetal Distress / Na^+-K^+-ATPase / Intracellular Na^+ concentration / Vasodepressor System / Vasopressor System / Calcium Metabolism / Pregnancy Induced Hypertension (PIH) / 降圧系 / 昇圧系 / vitamin D.ナ_<3.ニ> / 腸管カルシウム吸収 / ロールオーバーテスト / 血漿レニン活性(PRA) / 妊娠高血圧症(P1H) / 心房性ナトリウム利尿ホルモン / 推定胎児体重 / 胎盤機能 / パルスドップラー法 / 潜在性胎児仮死 / ナトリウムポンプ / 細胞内Na / 血圧調節ホルモン / カルシウム調節因子 / asialo-hCG / HCG / Thyroid function / Thyroid hormone / 甲状腺機能異常 / 絨毛 / Calcium / Metabolism During Pregnancy / Pregnancy Induced Yhpertension / Fetal Distress / Fetal Growth / カルシウム代謝 / 糖-脂質-蛋白質代謝 / 胎児発育 / intraarteial infusion / high dose chemotherapy / chemoflltration / neoadjuvant chemotherapy / uterine cervical carcinoma / STD / 体外循環 / CDDP / HPV / 抗癌剤毒性 / PPPEC / 高用量 / 動脈内投与 / 骨盤灌流化学療法 / 抗癌剤 / 子宮頚部癌 / decidua / invasion / matrigel / CAM / apoptosis / thyroid hormone / EVT / 絨毛外トロホブラスト / Fas / 絨毛外栄養膜細胞 / 浸潤能 / マトリゲル / 細胞接着関連分子 / Preeclampsia / Differentiation / Proliferation / Apoptosis / Extravillous trophoblast / Syncytiotrophoblast / Cytotrophoblast / Torophoblast / PIH / PCNA / PPAR / bcl-2 / 分化機能 / extravillous trophoblast / 絨毛細胞 / IGF-1 / Magnesium / Nitric Oxide / Fatty Acids / Hyperlipidemia / Platelet-Activating Factor / Pregnancy Induced Hypertension / エンドセリン / 液性因子 / マグネシウムイオン / カルシウムイオン / ナトリウムイオン / PAF-AH / プレゲステロン / エストラジオール / 血管内皮細胞 / 妊娠高血圧症(PIH) / 血小板活性化因子(PAF) / エンドセリン-1(ET-1) / マグネシウム / 一酸化窒素 / 脂肪酸 / 高脂血症 / 血小板活性化因子 / エンドセリン-I / 単クローン抗体 / 相補性DNA / シトシン塩基のメチル化 / 遺伝子発現 / 胎盤蛋白ホルモン / 免疫組織化学 / Molecular Hybridization / 繊毛癌 / 癌遺伝子 / 胎盤蛋白 / 遺伝 / PCR-RFLP / COMT / MMP / 相関解析 / 遺伝子多型 / 遺伝子 / 子宮体癌 / 活性炭吸着法 / 透析 / 吸着療法 / 動脈内化学療法 / 骨盤灌流 / シスプラチン / placeuta / EGF受容体 / EGF / cytotroblast Less
  • Research Projects

    (24 results)
  • Research Products

    (52 results)
  • Co-Researchers

    (25 People)
  •  Strategy for the development of new therapy for uterine leiomyoma based on the analysis of sex steroidal action in leiomyoma growthPrincipal Investigator

    • Principal Investigator
      OHARA Noriyuki, 丸尾 猛
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  絨毛外トロホブラスト浸潤能へのアクチン・ミオシン発現の関与とその局所・内分泌調節Principal Investigator

    • Principal Investigator
      丸尾 猛
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  遺伝疫学的アプローチによる子宮体癌発症関連遺伝子の解明

    • Principal Investigator
      OHARA Noriyuki
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  リラキシン(LGR7と8)の子宮内発現の解析とその細胞外ドメイン投与の効果Principal Investigator

    • Principal Investigator
      丸尾 猛
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Neoadjuvant high-dose intraarterial infusion chemotherapy under percutaneous pelvic perfusion with extracorporeal chemofiltration in patients with stage IIIa-IVa cervical cancer.

    • Principal Investigator
      MOTOYAMA Satoru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Research of endocrine regulation of the invasive potential and apoptosis extravillous trophoblastsPrincipal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  女性生殖器細胞の増殖、分化、アポトーシス調節におけるアドレノモデュリン発現の役割Principal Investigator

    • Principal Investigator
      丸尾 猛
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Molecular bases of the invasion of extavillous trophoblast to the decidua in human placenta

    • Principal Investigator
      MATSUO Hiroya
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      kobe University
  •  Molecular bases for the mechanism of apotosis regulation in placental trophoblast

    • Principal Investigator
      MATSUO Hiroya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  胎盤でのアポトーシス抑制遺伝子bcl・2発現の意義の解析とその周産期病態への関与Principal Investigator

    • Principal Investigator
      丸尾 猛
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  子宮頚癌に対する活性炭吸着体外循環回路を用いた超低毒性高用量骨盤潅流化学療法

    • Principal Investigator
      本山 覚
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Mechanism underlying the regulation of apoptosis in female reproductive cellsPrincipal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Molecular endocrinological study on the local regulatory mechanism of the proliferation, differentiation and apoptosis of female reproductive cellsPrincipal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Molecular endocrinological study on the regulatory mechanism of the proliferation and differentiation of female reproductive cellsPrincipal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  THE STUDY OF ETIOLOGY AND PATHOPHYSIOLOGY OF PREECLAMPSIA,ANALYSIS IN THE ASPECT OF INTRACELLULAR SIGNAL TRANSDUCTION

    • Principal Investigator
      MOCHIZUKI Matsuto
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      KOBE UNIVERSITY
  •  絨毛・脱落膜相関における細胞成長因子と癌遺伝子の作用機体に関する分子生物学的研究

    • Principal Investigator
      ASHITAKA Yoshihiko
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  The role of growth factors and oncogenes in the functional regulation of the ovary and placentaPrincipal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Basic and Clinical Studies on Roles of Calcium Metabolism in Female Reproductive Phenomena

    • Principal Investigator
      MOCHIZUKI Matsuo
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Studies on the Thyroid Hormone Actions in the Field of Reproduction

    • Principal Investigator
      ASHITAKA Yoshihiko
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  ヒト胎盤蛋白ホルモンならびに癌遺伝子の制御機構からみた繊毛の文化と癌化

    • Principal Investigator
      HOSHINA Makoto
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Research on pathophysiology, the prediction of onset and the prediction of latent fetal distress in toxemic pregnancy.

    • Principal Investigator
      MORIKAWA Hajime
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University
  •  Moleculon endocrinologieal stidies on the rcqulation of synthesis and socretion of hCG( , ) by trophoblastic and non-trophoblastic cells.Principal Investigator

    • Principal Investigator
      MARUO Takeshi
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University School of Medicine
  •  Integrated Studies on Endocrino-Metabolic Mechanisms of Fetal Growth and Fetal Distress

    • Principal Investigator
      MOCHIZUKI Matsuto
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University School of Medicine
  •  Studies on the Control Mechanism of Thyroid Function during Pregnancy and its Clinical Application, especially for a Possibility of Foeto-therapy.

    • Principal Investigator
      ASHITAKA Yoshihiko
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kobe University

All 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Translational research in uterine biology2008

    • Author(s)
      Ohara N, Xu Q, Matsuo H, Maruo T
    • Publisher
      Elsevier(In press)
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Book] 子宮筋腫研究の最近の話題と今後の展望. 子宮筋腫の臨床2008

    • Author(s)
      小原範之、丸尾猛
    • Publisher
      メジカルビュー社
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Book] Translational research in uterine biology2008

    • Author(s)
      Ohara N, Xu Q, Matsuo H, Maruo T
    • Publisher
      Elsevier, Amsterdam, Progesterone and progesterone receptor modulator in uterine leiomyoma growth
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Book] Translational research in uterine biology2008

    • Author(s)
      Ohara N, Xu Q, Matsuo H, Maruo T
    • Publisher
      Elsevier(In press)
    • Data Source
      KAKENHI-PROJECT-18659487
  • [Book] 子宮筋腫とSPRM : 子宮筋腫治療の新戦略. Annual Review 糖尿病・代謝・内分泌2008

    • Author(s)
      小原範之、丸尾猛
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells2008

    • Author(s)
      Xu Q, Ohara N, Liu J, Amano M, Sitruk-Ware R, Yoshida S, Maruo T
    • Journal Title

      Mol Hum Reprod 14

      Pages: 181-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] The effects of progesterone on apoptosis in the human trophoblast-derived HTR-8/SV neo cells2008

    • Author(s)
      Liu J, Matsuo H, Laoag-Fernandez JB, Xu Q, Maruo T
    • Journal Title

      Mol Hum Reprod (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer2008

    • Author(s)
      Morikawa A, Ohara N, Xu Q, Nakabayashi K, DeManno DA, Chwalisz K, Yoshida S, Maruo T
    • Journal Title

      Hum Reprod 23

      Pages: 944-951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellularmatrix metalloproteinase inducer2008

    • Author(s)
      Morikawa H, Ohara N, Xu Q, Nakabayashi K, DeManno DA, Chwalisz K, Yoshida s, Maruo T
    • Journal Title

      Hum Reprod 23

      Pages: 944-951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Effects of progesterone receptor modulator CDB-2914 0n the expression of extracellularmatrix proteins in cultured human uterine leiomyoma cells2008

    • Author(s)
      Xu Q, Ohara N, Liu J, Amano M, Sitruk-Ware R, Yoshida s, Maruo T
    • Journal Title

      Mol Hum Reprod 14

      Pages: 181-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Effects of levonorgestrel-releasing IUS and progesterone receptor modulator PRM CDB-2914 on uterine leiomyomas2007

    • Author(s)
      Maruo T, Ohara N, Matsuo H, Xu Q, Chen W, Sitruk-Ware R, Johansson EDB
    • Journal Title

      Contraception 75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Comparative effects of SPRM asoprisnil(J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells2007

    • Author(s)
      Ohara N, Morikawa A, Chen W, Wang J, DeManno DA, Chwalisz K, Maruo T
    • Journal Title

      Reprod Sci 14

      Pages: 20-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells2007

    • Author(s)
      Xu Q, Ohara N, Liu J, Nakabayashi K, DeManno D, Chwalisz K, Yoshida S, Maruo T
    • Journal Title

      Am J Physiol Endocrinol Metab 293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Concentration-dependent effects of a selective estrogen receptor modulator raloxifene on proliferation and apoptosis in human uterine leiomyoma cells cultured in vitro2007

    • Author(s)
      Liu J, Matsuo H, Xu Q, Chen W. Wang J, Maruo T
    • Journal Title

      Hum Reprod 22

      Pages: 1253-1259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells2007

    • Author(s)
      Xu Q, Ohara N, Liu J, Nakabayashi K, DeManno D, Chwalisz K, Yoshida S, Maruo T
    • Journal Title

      Am J Physiol Endocrinol Metab 293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] A novel selective progesterone receptor modulator Asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGF β 3, and their receptors in cultured uterine leiomyoma cells2006

    • Author(s)
      Wang J, Ohara N, Wang Z, Chen W, Morikawa A, Sasaki II, DeManno DA, Chwalisz K, Maruo T
    • Journal Title

      Hum Reprod 21

      Pages: 1869-1877

    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Matrix metal loproteinase-1 and -9 promoter polymorphisms and endometrial carcinoma risk in a Japanese population2006

    • Author(s)
      Sugimoto M, Yoshida S, Kennedy S, Deguchi M, Ohara N, Maruo T
    • Journal Title

      J Soc Gynecol Investig 13

      Pages: 523-529

    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells2006

    • Author(s)
      Xu Q, Ohara N, Chen W, Liu J, Sasaki H, Morikawa A, Sitruk-Ware R, Johansson ED, Maruo T
    • Journal Title

      Hum Reprod 21

      Pages: 2408-2416

    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Matrix metalloproteinase (MMP)-1 and MMP-9 promoter polymorphisms are not associated with an increased risk of uterine leiomyomas in a Japanese population2006

    • Author(s)
      Takemura N, Yoshida S, Kennedy S, Deguchi M, Ohara N, Maruo T
    • Journal Title

      J Soc Gynecol Investig 13

      Pages: 232-236

    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] A novel selective progesterone receptor modulator Asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells2006

    • Author(s)
      Chen W, Ohara N, Wnag J, Xu Q, Liu J, Morikawa A, Sasaki H, Yoshida S, DeManno DA, Chwalisz K, Maruo T
    • Journal Title

      J Clin Endocrinol Metab 91

      Pages: 1296-1304

    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] The CYP17 MspAl polymorphism is not associated with an increased risk of uterine leiomyomas in a Japanese population2006

    • Author(s)
      Tsujino T, Ohara N, Yoshida S, Kennedy S, Takemura N, Deguchi M, Maruo T
    • Journal Title

      Gynecol Endocrinol 22

      Pages: 87-91

    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] Prevention of postpartum hemorrhage by uterotonic agents : comparison of oxytocin and methylergometrine in the management of the third stage of labor2006

    • Author(s)
      Fujimoto M, Takeuchi K, Sugimoto M, Maruo T
    • Journal Title

      Acta Obstet Gynecol Scand 85

      Pages: 1310-1314

    • Data Source
      KAKENHI-PROJECT-18659487
  • [Journal Article] Association study of endometriosis and intercellular adhesion molecule-1 gene polymorphisms in a Japanese population2005

    • Author(s)
      Yamashita M, Yoshida S, Kennedy S, Ohara N, Motoyama S, Maruo T
    • Journal Title

      Journal of Society for Gynecologic Investigation 13

      Pages: 267-271

    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] 右心房に達した子宮原発静脈内平滑筋腫症の一例2005

    • Author(s)
      武木田茂樹, 本山 覚, 丸尾 猛
    • Journal Title

      産婦人科の進歩 57

      Pages: 32-36

    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] 女性性器クラミジア感染症に対するアジスロマイシン1000mg単回投与法の有用性2005

    • Author(s)
      本山 覚, 森山俊武, 丸尾 猛
    • Journal Title

      治療 87

      Pages: 984-989

    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Lack of association between endometriosis and the CYP 17 MspA1 polymorphisms in UK and Japanese populations2005

    • Author(s)
      Asghar T, Yoshida S, Nakago S, Morizane M, Ohara N, Motoyama S, Kennedy S, Barrow D, Maruo T
    • Journal Title

      Gynecologic Endocrinology 20

      Pages: 59-63

    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Lack of association between endometriosis and N-zcetyl transferase 1 and 2 polymorphisms in a Japanese population2005

    • Author(s)
      Deguchi M, Yoshida S, Kennedy S, Ohara N, Motoyama S, Maruo T
    • Journal Title

      Journal of Society for Gynecologic Investigation 12

      Pages: 208-213

    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Effect of cis-diamine dichioroplatinum on vascular endotherial grouth factor expression in uterine cervical carcinoma.2004

    • Author(s)
      Miyahara Y, Yoshida S, Motoyama S, Tateiwa Y, Hamana S, Maruo T.
    • Journal Title

      European Journal of Gynecology and Obstetrics 25

      Pages: 33-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Neoadjuvant High-dose Intraarterial Infusion Chemotherapy under Percutaneous Pelvic Perfusion with Extracorporeal Chemofiltration In Patients with Stage IIIa-IVa Cervical Cancer.2004

    • Author(s)
      Motoyama S, Hamana S, Ku Y, Fernandez J, Deguchi M, Yoshida S, Tominaga M, Iwasaki T, Ohara N, Maruo T.
    • Journal Title

      Gynecologic Oncology 95

      Pages: 576-582

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Transient increase in squamous cell carcinoma antigen expression in cultured cervical carcinoma Caski cells in response to exposure to Cisdiamminedichloroplatinum.2004

    • Author(s)
      Tateiwa Y, Yoshida S, Miyahara Y, Hamana S, Motoyam SMaruo T
    • Journal Title

      TUMOR BIOLOGY 24

      Pages: 219-227

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390506
  • [Journal Article] Effects of progesterone receptor modulator CDB-2914 on the expression of extracellular matrix proteins in cultured human uterine leiomyoma cells

    • Author(s)
      Xu Q, Ohara N, Liu J, Amano M, Sitruk-Ware R, Yoshida S, Maruo T
    • Journal Title

      Mol Hum Reprod (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Journal Article] Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer

    • Author(s)
      Morikawa H, Ohara N, Xu Q, Nakabayashi K, DeManno DA, Chwalisz K, Yoshida S, Maruo T
    • Journal Title

      Hum Reprod (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Attack on uterine fibroids by progesterone receptor modulator in a cell-type specific manner2008

    • Author(s)
      Maruo T
    • Organizer
      International Workshop on Uterine Fibroids
    • Place of Presentation
      Germany
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Attack on uterine fibroids by progesterone receptor modulator in acell-type specific manner2008

    • Author(s)
      Maruo T, et al
    • Organizer
      International Workshop on Uterine Fibroids
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and progesterone receptor modulator in uterine leiomyomagrowth: their implication in reproductive health2007

    • Author(s)
      Maruo T, Matsuo H, Samoto T, Nakago S, Xu Q, Chen W, Wang J, Ohara N
    • Organizer
      The 12th Annual Conference of Egyptian Fertility and Sterility Society
    • Place of Presentation
      Cairo, Egypt,
    • Data Source
      KAKENHI-PROJECT-18659487
  • [Presentation] Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured uterine leiomyoma cells2007

    • Author(s)
      Xu Q, Ohara N, Liu J, Sasaki H, Morikawa A, Yoshida S, DeManno D, Chwalisz K, Maruo T
    • Organizer
      The 20th Asian and Oceanic Congress of Obstetrics and Gynecology
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and progesterone receptor modulator in uterine leiomyoma growth: their implication in reproductive health2007

    • Author(s)
      Maruo T, Matsuo H, Samoto T, Nakago S, Xu Q, Chen W, Wang J, Ohara N
    • Organizer
      The 12th Annual Conference of Egyptian Fertility and Sterility Society
    • Place of Presentation
      Cairo, Egypt,
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells2007

    • Author(s)
      Xu Q, Ohara N, Liu J, Morikawa A, Sasaki H, Maruo T
    • Organizer
      第59回日本産科婦人科学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and progesterone receptor modulator in uterine leiomyoma growth : their implication in reproductive health2007

    • Author(s)
      Maruo T, Matsuo H, Samoto T, Nakago S, Xu Q, Chen W, Wang J, Ohara N
    • Organizer
      The 12th Annual Conference of the Egyptian Fertility and Sterility Society
    • Place of Presentation
      Cairo, Egypt
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Effects of CDB-2914 on ECM expression in cultured leiomyoma cells2007

    • Author(s)
      Maruo T
    • Organizer
      The 91th International Committee Meeting of the Population Council
    • Place of Presentation
      New York, USA
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] 子宮筋腫における選択的プロゲステロン受容体モデュレーターJ867のコラーゲン関連タンパク発現への影響の検討2007

    • Author(s)
      森川哲、小原範之、中林幸士、丸尾猛
    • Organizer
      第59回日本産科婦人科学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and progesterone receptor modulator in uterine leiomyoma growth. The Oxford-Kobe Biomedical Seminar2007

    • Author(s)
      Maruo T, Matsuo H, Ohara N, Samoto T, Nakago S, Xu Q, Chen W, Wang J
    • Organizer
      International Symposium on Translational Research in Uterine Biology
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Comparative effects of SPRM asoprisnil(J867)on the proliferation, apoptosis and the expression of growth factors and ECM in cultured uterine leiomyoma cells and normal myometrial cells2006

    • Author(s)
      Maruo T, Ohara N, Morikawa A, Chen W, Wang J, DeManno D, Chwalisz K
    • Organizer
      The 8th International Conference on the Extracellular Matrix of the Female Reproductive Tract
    • Place of Presentation
      Maui, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Comparative effects of progesterone and PRM CDB-2914 on cultured uterine leiomyoma cells and myometrial cells2006

    • Author(s)
      Maruo T, Matsuo H, Ohara N, Xu Q, Chen W, Sitruk-Ware R, Johansson EDB
    • Organizer
      The 89th International Committee Meeting of the Population Council
    • Place of Presentation
      New York, USA
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] SPRM asoprisnil(J867)inhibits the proliferation and induces apoptosis in cultured uterine leiomyoma cells but not in cultured normal myometrial cells2006

    • Author(s)
      Maruo T, Ohara N, Chen W, Wang J, DeManno D, Chwalisz K
    • Organizer
      The 12th World Congress of Gynecological Endocrinology
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] 選択的プロゲステロン受容体モデュレーターJ867は組織選択的に培養子宮筋腫細胞の増殖を阻害し、アポトーシスを誘導する2006

    • Author(s)
      森川哲、小原範之、陳衛、王佳茵、丸尾猛
    • Organizer
      第58回日本産科婦人科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Effects of CDB-2914 on PR-A and PR-B in leiomyoma and normal myometrium2006

    • Author(s)
      Maruo T
    • Organizer
      The 89th International Committee Meeting of the Population Council
    • Place of Presentation
      New York, USA
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and selective progesterone receptor modulator in uterine leiomyoma growth2006

    • Author(s)
      Maruo T, Matsuo H, Samoto T, Shimomura Y, Kurachi O, Nakago S, Yamada T, Xu Q, Chen W, Wang J, Ohara N
    • Organizer
      The 92th Annual Congress of the Korean Society of Obstetrics and Gynecology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone receptor modulator(CDB-2914) induces apoptosis and inhibits proliferation and VEGF expression in cultured uterine leiomyoma cells but not in cultured normal myometrial cells2006

    • Author(s)
      Maruo T, Ohara N, Xu Q, Chen W, Sitruk-Ware R, Johansson EDB
    • Organizer
      The XVIII FIGO World Congress of Gynecology and Obstetrics
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] プロゲステロン受容体モデュレーターCDB-2914は培養子宮筋腫細胞におけるVEGF, adrenomedullinとその受容体発現を抑制する2006

    • Author(s)
      徐沁、小原範之、佐々木紘子、陳衛、丸尾猛
    • Organizer
      第58回日本産科婦人科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] In vitro effects of progesterone and progesterone receptor modulator on uterine leiomyoma growth2006

    • Author(s)
      Maruo T, Ohara N, Matsuo H, Nakago S, Yamada T, Chen W, Xu Q, Wang J, Sitruk-Ware R, Johansson EDB
    • Organizer
      The XVIII FIGO World Congress of Gynecology and Obstetrics
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Data Source
      KAKENHI-PROJECT-18390449
  • [Presentation] Progesterone and selective progesterone receptor modulator in uterine leiomyoma growth.International Seminar in Reproductive Endocrinology2006

    • Author(s)
      Maruo T, Matsuo H, Xu Q, Chen W, Wang J, Ohara N
    • Place of Presentation
      Siena, Italy
    • Year and Date
      2006-02-28
    • Data Source
      KAKENHI-PROJECT-18390449
  • 1.  MOCHIZUKI Matsuto (80030922)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  MATSUO Hiroya (60229432)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 14 results
  • 3.  ASHITAKA Yoshihiko (10030959)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  OHARA Noriyuki (70214210)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 31 results
  • 5.  OTANI Tetsuo (50203823)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  NAKABAYASHI Koji (80362789)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 7.  DEGUCHI Masaki (70163938)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  MORIKAWA Hajime (30030894)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  UEDA Yasuo (20168636)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  MOTOYAMA Satoru (80283878)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 11.  TAKEKIDA Shigeki (60324927)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SATO Asomi (90314484)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  YOSHIDA Shigeki (70294212)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 14.  YAMASAKI Mineo (00220301)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  NAKAGO Satoshi (50283891)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  佐本 崇 (80294213)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  KU Yonsoa (40195615)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 18.  HAMANA Shinya (00335449)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 19.  HOSHINA Makoto (30116248)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  BO Masaki (40243315)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  KATAYAMA Kazuaki (70112084)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  OHASHI Masanobu (90176975)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  竹内 聡 (60252772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  武内 享介 (80273770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  西村 隆一郎 (00127383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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