Kishioka Shiro 岸岡史郎

… Alternative Names

KISHIOKA Shiroh 岸岡史郎

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Researcher Number	60137255
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 薬学部, 学長特命教員(特別顧問) 2025: 宝塚医療大学, 和歌山保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 和歌山県立医科大学, 薬学部, 学長特命教員(特別顧問) 2019: 和歌山県立医科大学, 医学部, 学長特命教員(特別顧問) 2006 – 2018: 和歌山県立医科大学, 医学部, 教授 2007 – 2008: 和歌山県立医科大学, 医学部・薬理学, 教授 2007: Wakayama Medical University, Professor
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Pain science / Pain science / Psychiatric science Except Principal Investigator Anesthesiology/Resuscitation studies / Pain science / Pharmacology in pharmacy / Biological pharmacy / Sports science
Keywords	Principal Investigator 神経炎症 / サイトカイン / マクロファージ / 神経障害性疼痛 / Jak-STAT / PPARγ / ケモカイン / 坐骨神経 / 炎症 / 慢性疼痛 … More / ニコチン / 化学療法薬 / 糖尿病 / アロディニア / 末梢神経 / DREADD / ミクログリア / ニコチン性アセチルコリン受容体 / STAT3 / α4β2 / ニコチン受容体 / フェノタイプ / 慢性炎症 / neuropathic pain / inflammatory cytokine / PPAR / 疼痛 / 神経因性疼痛 / 炎症性サイトカイン / CXCR4 / エピジェネティクス / ネットワーク / 血管内皮細胞 / VEGF / 血管新生 / ナルトレキソン / モルヒネ / オピオド / 鎮痛 / 耐性 / ナロキソン / 退薬症状 / 身体的依存 / 依存 / コルチコステロン / オピオイド / アルコール … More Except Principal Investigator 神経障害性疼痛 / マクロファージ / ケモカイン / サイトカイン / 坐骨神経 / アロディニア / 生活習慣病 / 脂肪細胞 / レプチン / アディポカイン / ニューロペプチド / 中枢感作 / 脊髄 / ニコチン受容体 / 2型糖尿病 / 末梢感作 / 脊髄後角 / ミクログリア / 神経炎症 / セマフォリン / がん疼痛 / VEGF / MIP / CCL8 / フェノタイプ / CCL3 / 炎症 / エピジェネティクス / ヒストン / 慢性疼痛 / HMGB1 / ヌクレオカイン / クロマチン免疫沈降 / 疼痛 / 高脂肪食 / 疼痛管理学 / PPAR / 神経因性疼痛 / アディポネクチン / ミクロソ-ム / ESR / ミクロソーム / EPR / スピントラッピング / 脂質過酸化 / ラジカル / ミオグロビン / 急性腎不全 / 横紋筋融解症 Less

Mechanisms-based therapeutic strategies for neuropathic pain through peripheral macrophagesPrincipal Investigator
- Principal Investigator
  
  Kishioka Shiroh
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Wakayama Medical University
Pathogenesis of neuropathic pain due to interaction between peripheral and central sensitization
- Principal Investigator
  
  Kiguchi Norikazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Novel therapeutics for macrophage-driven inflammatory diseases via nicotinic acetylcholine receptor signalingPrincipal Investigator
- Principal Investigator
  
  Kishioka Shiroh
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Wakayama Medical University
骨転移痛におけるセマフォリンの病態生理学的役割の解析
- Principal Investigator
  
  尾崎昌宣
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
Identification of crosstalk between pathological angiogenesis and neurons in regulating chronic painPrincipal Investigator
- Principal Investigator
  
  KISHIOKA Shiroh
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Molecular mechanism of chronic pain via histone-dependent peripheral sensitization
- Principal Investigator
  
  KIGUCHI Norikazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Study on pathophysiological mechanism underlying leptin-induced exacerbation of neuropathic pain
- Principal Investigator
  
  OZAKI Masanobu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
Study on neuropathic pain associated with pre-diabetes and obese
- Principal Investigator
  
  MAEDA Takehiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
  Wakayama Medical University
Involvement of opioid system in nicotine and alcohol dependencePrincipal Investigator
- Principal Investigator
  
  KISHIOKA Shiroh
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Wakayama Medical University
神経因性疼痛増悪因子としてのアディポサイトカインに関する研究
- Principal Investigator
  
  KIGUCHI Norikazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Detection and identification of lipid-derived radicals formed by myoglobin released from damaged skeletal muscles after excessive exercise
- Principal Investigator
  
  KUMAMOTO Kazumasa
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  Kinki University
Ligands for peroxisome proliferaoractivated receptor as possible novel analgesicPrincipal Investigator
- Principal Investigator
  
  SHIROH Kishioka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University

[Book] Chapter 13 PPAR and Pain 852009
- Author(s)
  前田武彦, 岸岡史郎
- Publisher
  Int.Rev.Neurobiol
- Data Source
  KAKENHI-PROJECT-20591376
[Book] Chapter 14 Involvement of inflammatory mediators in neuropathic pain caused by vincristine 852009
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Saika F, Kishioka S
- Publisher
  Int.Rev.Neurobiol
- Data Source
  KAKENHI-PROJECT-20591376
[Book] エッセンシャル神経科学(シナプス伝達(分担訳),第II部ニューロン)(前田正信監訳)2008
- Author(s)
  前田武彦, 岸岡史郎
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-20591376
[Book] エッセンシャル神経科学(分担訳)2008
- Author(s)
  岸岡史郎, 他
- Total Pages
  574
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-19659404
[Book] エッセンシャル神経科学(分担訳)2008
- Author(s)
  岸岡史郎, 他
- Total Pages
  574
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-20591376
[Book] エッセンシャル神経科学(神経伝達物質(分担訳),第II部ニューロン)(前田正信監訳)2008
- Author(s)
  岸岡史郎
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-20591376
[Book] グッドマン・ギルマン薬理書[上]薬物治療の基礎と臨床第11版2007
- Author(s)
  岸岡史郎
- Total Pages
  60
- Publisher
  広川書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613014
[Journal Article] Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates.2023
- Author(s)
  Ding H, Kiguchi N, Mabry KM, Kishioka S, Ko MC.
- Journal Title
  
  Neuropharmacology.
  
  Volume: 223 Pages: 109328-109328
- DOI
  10.1016/j.neuropharm.2022.109328
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K09227
[Journal Article] Functional roles of neuromedin B and gastrin-releasing peptide in regulating itch and pain in the spinal cord of non-human primates.2022
- Author(s)
  Kiguchi N, Ding H, Park SH, Mabry KM, Kishioka S, Shiozawa Y, Alfonso Romero-Sandoval E, Peters CM, Ko MC.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 198 Pages: 114972-114972
- DOI
  10.1016/j.bcp.2022.114972
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K09227
[Journal Article] Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice2021
- Author(s)
  Saika Fumihiro、Matsuzaki Shinsuke、Kishioka Shiroh、Kiguchi Norikazu
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 4 Pages: 874-874
- DOI
  10.3390/cells10040874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
[Journal Article] Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice Pharmacology Research and Perspective2021
- Author(s)
  Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y. Nakamura, Mei-Chuan Ko, Shiroh Kishioka
- Journal Title
  
  Pharmacology Research and Perspective
  
  Volume: - Issue: 3 Pages: 1-11
- DOI
  10.1002/prp2.790
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227
[Journal Article] Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain2020
- Author(s)
  Fumihiro Saika, Shinsuke Matsuzaki, Daichi Kobayashi, Yuya Ideguchi, Tomoe Y Nakamura, Shiroh Kishioka, Norikazu Kiguchi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 925-925
- DOI
  10.3389/fphar.2020.00925
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-20K07088, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-19K16697
[Journal Article] GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn2020
- Author(s)
  Kiguchi Norikazu、Uta Daisuke、Ding Huiping、Uchida Hitoshi、Saika Fumihiro、Matsuzaki Shinsuke、Fukazawa Yohji、Abe Manabu、Sakimura Kenji、Ko Mei-Chuan、Kishioka Shiroh
- Journal Title
  
  Neuropharmacology
  
  Volume: 170 Pages: 108025-108025
- DOI
  10.1016/j.neuropharm.2020.108025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07111, KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19K09323, KAKENHI-PROJECT-20K07088
[Journal Article] Nociceptin/Orphanin FQ Peptide Receptor-Related Ligands as Novel Analgesics.2020
- Author(s)
  Kiguchi N, Ding H, Kishioka S, Ko MC.
- Journal Title
  
  Curr Top Med Chem
  
  Volume: 20 Issue: 31 Pages: 2878-2878
- DOI
  10.2174/1568026620666200508082615
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09333
[Journal Article] Insufficient efferocytosis by M2-like macrophages as a possible mechanism of neuropathic pain induced by nerve injury.2020
- Author(s)
  Kobayashi D, Kiguchi N, Saika F, Kishioka S, Matsuzaki S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: Epub Issue: 1 Pages: 216-223
- DOI
  10.1016/j.bbrc.2020.02.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09333, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-19K16697
[Journal Article] Inflammatory Macrophages in the Sciatic Nerves Facilitate Neuropathic Pain Associated with Type 2 Diabetes Mellitus.2019
- Author(s)
  Saika F, Kiguchi N, Matsuzaki S, Kobayashi D, Kishioka S.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 368(3) Issue: 3 Pages: 535-544
- DOI
  10.1124/jpet.118.252668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-16K08994
[Journal Article] A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.2018
- Author(s)
  Ding H, Kiguchi N, Yasuda D, Daga PR, Polgar WE, Lu JJ, Czoty PW, Kishioka S, Zaveri NT, Ko MC.
- Journal Title
  
  Sci Transl Med
  
  Volume: 10(456) Issue: 456
- DOI
  10.1126/scitranslmed.aar3483
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Journal Article] Differential mRNA expression of neuroinflammatory modulators in the spinal cord and thalamus of type 2 diabetic monkeys.2018
- Author(s)
  Ding H, Kiguchi N, Kishioka S, Ma T, Peters CM, Ko MC.
- Journal Title
  
  J Diabetes
  
  Volume: 10(11) Issue: 11 Pages: 886-895
- DOI
  10.1111/1753-0407.12780
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Journal Article] Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury2018
- Author(s)
  Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S
- Journal Title
  
  J Neuroinflammation
  
  Volume: 15 Issue: 1 Pages: 96-96
- DOI
  10.1186/s12974-018-1133-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08994, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-15K10563
[Journal Article] Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages2017
- Author(s)
  Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 11 Pages: 2296-2296
- DOI
  10.3390/ijms18112296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08994, KAKENHI-PROJECT-17K15758, KAKENHI-PROJECT-15K10563
[Journal Article] Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys2017
- Author(s)
  Kiguchi N, Ding H, Peters CM, Kock ND, Kishioka S, Cline JM, Wagner JD, Ko MC
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1863 Issue: 1 Pages: 274-283
- DOI
  10.1016/j.bbadis.2016.10.007
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10563, KAKENHI-PROJECT-16K08994
[Journal Article] Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation2017
- Author(s)
  Kiguchi Ｎ, Sakaguchi H, Kadowaki Y, Saika F, Fukazawa Y, Matsuzaki S, Kishioka S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 133 Issue: 1 Pages: 53-56
- DOI
  10.1016/j.jphs.2016.11.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10563, KAKENHI-PROJECT-16K08994
[Journal Article] Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain.2015
- Author(s)
  Kiguchi N, Kobayashi Y, Saika F, Sakaguchi H, Maeda T, Kishioka S
- Journal Title
  
  Pain
  
  Volume: 156(4) Issue: 4 Pages: 684-93
- DOI
  10.1097/j.pain.0000000000000097
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25460108, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Journal Article] Peripheral alpha4beta2 nicotinic acetylcholine receptor signalling attenuates tactile allodynia and thermal hyperalgesia after nerve injury in mice.2015
- Author(s)
  Saika F, Kiguchi N, Kobayashi Y, Kishioka S
- Journal Title
  
  Acta Physiol (Oxf)
  
  Volume: 213(2) Issue: 2 Pages: 462-71
- DOI
  10.1111/apha.12437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Journal Article] Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain.2014
- Author(s)
  Kiguchi N, Kobayashi Y, Kadowaki Y, Fukazawa Y, Saika F, Kishioka S
- Journal Title
  
  J Neurochem
  
  Volume: 129 Issue: 1 Pages: 169-178
- DOI
  10.1111/jnc.12614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397
[Journal Article] Epigenetic regulation of CC-chemokine ligand 2 in nonresolving inflammation.2014
- Author(s)
  Kiguchi N, Saika F, Kobayashi Y, Kishioka S
- Journal Title
  
  Biomol Concepts
  
  Volume: 5(4) Issue: 4 Pages: 265-73
- DOI
  10.1515/bmc-2014-0022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397, KAKENHI-PROJECT-26860357
[Journal Article] 傷害末梢神経におけるヒストン修飾は神経障害性疼痛を調節する.2014
- Author(s)
  木口倫一、岸岡史郎
- Journal Title
  
  Pain Research
  
  Volume: 29 Pages: 9-16
- NAID
  130004839642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592356
[Journal Article] Possible Involvement of Endogenous Opioid System Located Downstream of <i>α</i>7 Nicotinic Acetylcholine Receptor in Mice With Physical Dependence on Nicotine2014
- Author(s)
  Ueno K1, Kiguchi N, Kobayashi Y, Saika F, Wakida N, Yamamoto C, Maeda T, Ozaki M, Kishioka S.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Issue: 1 Pages: 47-53
- DOI
  10.1254/jphs.13172FP
- NAID
  130003382624
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-25460108
[Journal Article] Possible involvement of endogenous opioid system located downstream of 7 nicotinic acetylcholine receptor in mice with physical dependence on nicotine.2014
- Author(s)
  Ueno K, Kiguchi N, Kobayashi Y, Saika F, Wakida N, Yamamoto C, Maeda T, Ozaki M, Kishioka S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730
[Journal Article] Epigenetic upregulation of CCL2 and CCL3 via histone modifications in infiltrating macrophages after peripheral nerve injury.2013
- Author(s)
  Kiguchi N, Kobayashi Y, Saika F, Kishioka S
- Journal Title
  
  Cytokine
  
  Volume: 64 Issue: 3 Pages: 666-672
- DOI
  10.1016/j.cyto.2013.09.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397
[Journal Article] HMGB1 as a Potential Therapeutic Target for Neuropathic Pain2013
- Author(s)
  Maeda T1, Ozaki M, Kobayashi Y, Kiguchi N, Kishioka S.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 123 Issue: 4 Pages: 301-305
- DOI
  10.1254/jphs.13R08CP
- NAID
  130003382621
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-25460108
[Journal Article] Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice.2013
- Author(s)
  Kishioka S, Kiguchi N, Kobayashi Y, Yamamoto C, Saika F, Wakida N, Ko MC, Woods JH
- Journal Title
  
  Neurosci Lett
  
  Volume: 552 Pages: 98-102
- DOI
  10.1016/j.neulet.2013.07.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356, KAKENHI-PROJECT-25861397
[Journal Article] Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms2012
- Author(s)
  Iwai S, Kiguchi N, Kobayashi Y, Fukazawa Y, Saika F, Ueno K, Yamamoto C, Kishioka S
- Journal Title
  
  Drug Discov Ther
  
  Volume: 6 Pages: 31-37
- NAID
  130005054734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592356
[Journal Article] CC-chemokine ligand 4/macrophage inflammatory protein-1β participates in the induction of neuropathic pain after peripheral nerve injury.2012
- Author(s)
  Saika F, Kiguchi N, Kobayashi Y, Fukazawa Y, and Kishioka S
- Journal Title
  
  Eur J Pain.
  
  Volume: 16 Issue: 9 Pages: 1271-1280
- DOI
  10.1002/j.1532-2149.2012.00146.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356
[Journal Article] Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain2012
- Author(s)
  Kiguchi N, et al
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 340 Issue: 3 Pages: 577-587
- DOI
  10.1124/jpet.111.187724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791469, KAKENHI-PROJECT-22590090, KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356
[Journal Article] Chemokines and cytokines in neuroinflammation leading to neuropathic pain2012
- Author(s)
  Kiguchi N, et al
- Journal Title
  
  Curr Opin Pharmacol
  
  Volume: 12(invited) Issue: 1 Pages: 55-61
- DOI
  10.1016/j.coph.2011.10.007
- Data Source
  KAKENHI-PROJECT-21791469, KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24592356
[Journal Article] The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice2012
- Author(s)
  Kobayashi Y, Kiguchi N, Maeda T, Ozaki M, Kishioka S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 421 Issue: 2 Pages: 318-322
- DOI
  10.1016/j.bbrc.2012.03.153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590090, KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356
[Journal Article] Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms2012
- Author(s)
  Iwai S, Kiguchi N, Kobayashi Y, Fukazawa Y, Saika F, Ueno K, Yamamoto C, Kishioka S
- Journal Title
  
  Drug Discov Ther
  
  Volume: 6 Pages: 31-37
- NAID
  130005054734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590730
[Journal Article] Activation of nicotinic acetylcholine receptors on bone marrow-derived cells relieves neuropathic pain accompanied by peripheral neuroinflamation.2012
- Author(s)
  Kiguchi N, Kobayashi Y, Maeda T, Tominaga S, Nakamura J, Fukazawa Y, Ozaki M and Kishioka S
- Journal Title
  
  Neurochem Int.
  
  Volume: 61 Issue: 7 Pages: 1212-1219
- DOI
  10.1016/j.neuint.2012.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791724, KAKENHI-PROJECT-24590730, KAKENHI-PROJECT-24590734, KAKENHI-PROJECT-24592356
[Journal Article] Availability of serum corticosterone level for quantitative evaluation of morphine withdrawal in mice2011
- Author(s)
  Ueno K, Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S.
- Journal Title
  
  Drug Discov Ther
  
  Volume: 5 Pages: 71-75
- NAID
  130005054697
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22466143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590090
[Journal Article] Availability of serum corticosterone level for quantitative evaluation of morphine withdrawal in mice.2011
- Author(s)
  Ueno K, Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S
- Journal Title
  
  Drug Discov.Ther. 5(2)
  
  Pages: 71-75
- NAID
  130005054697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Macrophage inflammatory protein-1 alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1 beta up-regulation.2010
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S
- Journal Title
  
  Pain 149(2)
  
  Pages: 305-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Increment of activated serine/threonine protein phosphatase in brain membrane fraction synchronized with antinociceptive effect of morphine in mice.2010
- Author(s)
  Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S
- Journal Title
  
  Biol.Pharm.Bull. 33(6)
  
  Pages: 1011-1014
- NAID
  130000247970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Macrophage inflammatory protein-1 α mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1β up-regulation2010
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S
- Journal Title
  
  Pain
  
  Volume: 149 Pages: 305-315
- URL
  http://dx.doi.org/10.1016/j.pain.2010.02.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592023
[Journal Article] Increment of activated serine/threonine protein phosphatase in brain membrane fraction synchronized with antinociceptive effect of morphine in mice2010
- Author(s)
  Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S
- Journal Title
  
  Biol.Pharm. Bull.
  
  Volume: 33 Pages: 1011-1014
- NAID
  130000247970
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20522968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590090
[Journal Article] CC-chemokine MIP-1α in the spinal cord contributes to nerve injury-induced neuropathic pain.2010
- Author(s)
  Kiguchi N, Kobayashi Y, Maeda T, Saika F, Kishioka S
- Journal Title
  
  Neurosci.Lett. 484
  
  Pages: 17-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] The pharmacological mechanisms of electroacupuncture.2009
- Author(s)
  Fukazawa Y, Maeda T, Kishioka S
- Journal Title
  
  Curr.Opin.Investig.Drugs 10(1)
  
  Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation2009
- Author(s)
  Maeda T, Kiguchi N, Kobayashi Y, Ikuta T, Ozaki M, Kishioka S
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 106 Issue: 31 Pages: 13076-13081
- DOI
  10.1073/pnas.0903524106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592023
[Journal Article] Activation of extracellular signal-regulated kinase in sciatic nerve contributes to neuropathic pain after partial sciatic nerve ligation in mice.2009
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S
- Journal Title
  
  Anesth.Analg. 109(4)
  
  Pages: 1305-1311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Leptin enhances CC-chemokine ligand expression in cultured murine macrophage.2009
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 384(3)
  
  Pages: 311-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation.2009
- Author(s)
  Maeda T, Kiguchi N, Kobayashi Y, Ikuta T, Ozaki M, Kishioka S
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(31)
  
  Pages: 13076-13081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Modulation of opioid actions by nitric oxide signaling.2009
- Author(s)
  Toda N, Kishioka S, Hatano Y, Toda H
- Journal Title
  
  Anesthesiology 110(1)
  
  Pages: 166-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice.2008
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Kondo T, Ozaki M, Kishioka S
- Journal Title
  
  Eur.J.Pharmacol. 592(1-3)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury.2008
- Author(s)
  Maeda T, Kiguchi N, Kobayashi Y, Ozaki M, Kishioka S
- Journal Title
  
  J.Pharmacol.Sci. 108(3)
  
  Pages: 341-347
- NAID
  10024593242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice.2008
- Author(s)
  Kiguchi N, Maeda T, Tsuruga M, Yamamoto A, Yamamoto C, Ozaki M, Kishioka S
- Journal Title
  
  Brain Res. 1189
  
  Pages: 70-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Up-regulation of tumor necrosis factor-alpha in spinal cord contributes to vincristine-induced mechanical allodynia in mice.2008
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Kishioka S
- Journal Title
  
  Neurosci.Lett. 445
  
  Pages: 140-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591376
[Journal Article] Identification of a radical formed in the reaction mixture of rat brain homogenate with a ferrous ion/ascorbic acid system using HPLC-EPR and HPLC-EPR-MS2007
- Author(s)
  Kumamoto K, Hirai T, Kishioka S, Iwahashi H
- Journal Title
  
  Free Radical Research 41(6)
  
  Pages: 650-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500519
[Journal Article] Identification of a radical formed in the reaction mixture of rat brain homogenate with ferrous ion/ascorbic acid using HPLC-ESR and HPLC-ESR-MS2006
- Author(s)
  Kumamoto K, Hirai T, Kishioka S, Iwahashi H
- Journal Title
  
  Proceeding of The 13^<th> Congress of the Society for Free radical Research International (Davos, Swjtzerland, August 15-19, 2006) CD-ROM
- Data Source
  KAKENHI-PROJECT-18500519
[Presentation] DREADDシステムを用いたマクロファージ／ミクログリア機能制御が神経障害性疼痛モデルに及ぼす疼痛抑制効果.2020
- Author(s)
  雑賀史浩, 木口倫一, 小林大地, 出口雄也, 松﨑伸介, 岸岡史郎.
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K09333
[Presentation] 末梢性神経障害性疼痛治療薬としてのニコチン受容体作動薬の可能性.2019
- Author(s)
  岸岡史郎, 木口倫一, 雑賀史浩.
- Organizer
  令和元年度東北医科薬科大学創薬研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K09333
[Presentation] 神経障害性疼痛に関与するマクロファージ／ミクログリアの機能解析.2018
- Author(s)
  雑賀史浩, 木口倫一, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] Inflammatory macrophages mediate neuropathic pain caused by type 2 diabetes mellitus.2018
- Author(s)
  Kiguchi N, Saika F, Kobayashi D, Matsuzaki S, Kishioka S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経障害性疼痛モデルマウスを用いた抗炎症性マクロファージの機能解析.2018
- Author(s)
  小林大地, 木口倫一, 雑賀史浩, 松﨑伸介, 岸岡史郎.
- Organizer
  第38回鎮痛薬・オピオイドペプチドシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] α4β2 ニコチン性アセチルコリン受容体アゴニストはマウスにおける2型糖尿病性神経障害性疼痛を減弱する.2018
- Author(s)
  雑賀史浩, 木口倫一, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 炎症性マクロファージは神経傷害後のミクログリア活性化および機械的アロディニアを調節する.2018
- Author(s)
  木口倫一, 雑賀史浩, 小林大地, 松﨑伸介, 岸岡史郎.
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 非ヒト霊長類における疼痛制御因子の発現と機能解析.2018
- Author(s)
  木口倫一, 岸岡史郎, Mei-Chuan Ko.
- Organizer
  第38回鎮痛薬・オピオイドペプチドシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] Inflammatory macrophages in the injured peripheral nerves facilitate spinal microglial activation and neuropathic pain in mice.2018
- Author(s)
  Kiguchi N, Saika F, Kobayashi D, Matsuzaki S, Kishioka S.
- Organizer
  17th World Congress on Pain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経傷害後の末梢マクロファージによる脊髄ミクログリア調節作用2017
- Author(s)
  木口倫一、小林大地、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] 傷害神経に浸潤するマクロファージは脊髄ミクログリアの活性化を調節する2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松﨑伸介、岸岡史郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 2型糖尿病発症カニクイザルの脊髄後角におけるケモカイン発現変動2017
- Author(s)
  木口倫一、Huiping Ding、雑賀史浩、松﨑伸介、岸岡史郎、Mei-Chuan Ko
- Organizer
  生理学研究所研究会「痛みの理解を目指した先端的アプローチ」
- Place of Presentation
  岡崎
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] 2型糖尿病発症カニクイザルの脊髄後角におけるケモカイン発現変動2017
- Author(s)
  木口倫一、Huiping Ding、雑賀史浩、松﨑伸介、岸岡史郎、Mei-Chuan Ko
- Organizer
  生理学研究所研究会「痛みの理解を目指した先端的アプローチ」
- Place of Presentation
  岡崎
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] マクロファージ上で発現するα4β2ニコチン性アセチルコリン受容体活性化による神経障害性疼痛の緩和2017
- Author(s)
  雑賀史浩、木口倫一、松﨑伸介、岸岡史郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] ニコチン性アセチルコリン受容体リガンドの末梢投与は神経障害性疼痛を改善する2017
- Author(s)
  木口倫一、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第5回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 神経傷害後の末梢マクロファージによる脊髄ミクログリア調節作用2017
- Author(s)
  木口倫一、小林大地、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] 傷害神経に浸潤するマクロファージは脊髄ミクログリアの活性化を調節する2017
- Author(s)
  木口倫一、雑賀史浩、小林大地、松﨑伸介、岸岡史郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] マクロファージ上で発現するα4β2ニコチン性アセチルコリン受容体活性化による神経障害性疼痛の緩和2017
- Author(s)
  雑賀史浩、木口倫一、松﨑伸介、岸岡史郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K08994
[Presentation] ニコチン性アセチルコリン受容体リガンドの末梢投与は神経障害性疼痛を改善する2017
- Author(s)
  木口倫一、雑賀史浩、松﨑伸介、岸岡史郎
- Organizer
  第5回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-15K10563
[Presentation] IL-13 はマクロファージのフェノタイプシフトによって神経障害性疼痛を緩和する2015
- Author(s)
  阪口晴香、木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 末梢免疫細胞を標的とした神経障害性疼痛病態の解明2015
- Author(s)
  小林悠佳、木口倫一、深澤洋滋、雑賀史浩、前田武彦、岸岡史郎
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] マクロファージ由来血管内皮細胞増殖因子は神経障害性疼痛に関与する2015
- Author(s)
  門脇友維、小林悠佳、木口倫一、雑賀史浩、岸岡史郎
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 末梢免疫細胞を標的とした神経障害性疼痛病態の解明2015
- Author(s)
  小林悠佳、木口倫一、深澤洋滋、雑賀史浩、前田武彦、岸岡史郎
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 末梢性神経障害性疼痛におけるマクロファージ由来血管内皮細胞増殖因子（VEGF）の関与2014
- Author(s)
  門脇友維、小林悠佳、木口倫一、雑賀史浩、岸岡史郎
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] Peripheral macrophages in long-lasting neuroinflammation and neuropathic pain.2014
- Author(s)
  Kiguchi N, Kishioka S
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] Peripheral macrophages in long-lasting neuroinflammation and neuropathic pain.2014
- Author(s)
  Kiguchi N, Kishioka S
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 傷害坐骨神経周囲の新生血管網形成とマクロファージ2014
- Author(s)
  小林悠佳、木口倫一、雑賀史浩、門脇友維、岸岡史郎
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] IL-4はマクロファージの機能調節を介して神経障害性疼痛を改善する2014
- Author(s)
  木口倫一、小林悠佳、岸岡史郎
- Organizer
  第36回日本疼痛学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] Vascular endothelial growth factor signaling in injured nerves mediates peripheral sensitization in neuropathic pain.2014
- Author(s)
  Kiguchi N, Kobayashi Y, Kadowaki Y, Saika F, Kishioka S
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-23
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] マクロファージを標的とした神経障害性疼痛治療戦略の検討2014
- Author(s)
  木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第34回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] IL-13は末梢神経傷害時の炎症性マクロファージを抑制する2014
- Author(s)
  阪口晴香、木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] マクロファージを標的とした神経障害性疼痛治療戦略の検討2014
- Author(s)
  木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第34回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] Nicotine stimulates opioid system through the activation of nicotinic acetylcholine receptor.2010
- Author(s)
  Kishioka S, Ueno K, Yamamoto C, Yamamoto A, Saika F, Iwai S, Kobayashi Y, Kiguchi N, Maeda T
- Organizer
  The International Narcotics Research Conference 2010
- Place of Presentation
  Malmo, Sweden
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Leptin and neuropathic pain2010
- Author(s)
  Kishioka S, Maeda T
- Organizer
  Molecular Targets for Novel Pain Therapeutics From basic research to clinical translation
- Place of Presentation
  Calabria, Italy
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21592023
[Presentation] Leptin and neuropathic pain2010
- Author(s)
  Kishioka S, Maeda T
- Organizer
  Molecular Targets for Novel Pain Therapeutics From basic research to clinical translation
- Place of Presentation
  Calabria, Italy
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Nicotine stimulates opioid system through the activation of nicotinic acetylcholine receptor2010
- Author(s)
  Kishioka S, et al.
- Organizer
  The International Narcotics Research Conference 2010
- Place of Presentation
  Malmo, Sweden
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Serum corticosterone increase is a useful indicator to quantify the magnitude of naloxone-precipitated morphine withdrawal in mice2010
- Author(s)
  Kishioka S, et al.
- Organizer
  Neuroscience2010
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Serum corticosterone increase is a useful indicator to quantify the magnitude of naloxone-precipitated morphine withdrawal in mice.2010
- Author(s)
  Kishioka S, Ueno K, Yamamoto A, Yamamoto C, Kobayashi Y, Kiguchi N, Maeda T
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Leptin and neuropathic pain.2010
- Author(s)
  Kishioka S, Maeda T
- Organizer
  Molecular Targets for Novel Pain Therapeutics From basic research to clinical translation
- Place of Presentation
  Calabria. Italy
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] レプチンの神経障害性疼痛における役割2010
- Author(s)
  前田武彦、木口倫一、小林悠佳、岸岡史郎
- Organizer
  第15回アディポサイエンス研究会シンポジウム
- Place of Presentation
  吹田
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21592023
[Presentation] Role of macrophage inflammatory protein-1 in the pathogenesis of neuropathic pain.2010
- Author(s)
  Kiguchi N, Maeda T, Kobayashi Y, Kishioka S
- Organizer
  Molecular Targets for Novel Pain Therapeutics From basic research to clinical translation
- Place of Presentation
  Calabria, Italy
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] HMGB1によるレプチンシグナル活性化は神経障害性疼痛の形成に関与する2010
- Author(s)
  前田武彦, 木口倫一, 小林悠佳, 岸岡史郎
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592023
[Presentation] HMGB1によるレプチンシグナル活性化は神経障害性疼痛の形成に関与する2010
- Author(s)
  前田武彦, 木口倫一, 小林悠佳, 岸岡史郎
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Leptin and neuropathic pain2010
- Author(s)
  Kishioka S, Maeda T
- Organizer
  Molecular Targets for Novel Pain Therapeutics From basic research to clinical translation
- Place of Presentation
  Calabria, Italy
- Data Source
  KAKENHI-PROJECT-22590090
[Presentation] Inhibition of morphine tolerance under the several pain conditions in mice.2009
- Author(s)
  Iwai S, Kiguchi N, Kobayashi Y, Maeda T, Kishioka S
- Organizer
  The 1^<st> meeting of the Asian College of Neuropsychopharmacology
- Place of Presentation
  Kyoto
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] アディポカインは神経障害性疼痛の形成を調節する2009
- Author(s)
  前田武彦、岸岡史郎
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-21592023
[Presentation] Development of tolerance to nicotine-induced corticosterone increase and antinociception in mice.2009
- Author(s)
  Kishioka S, Ueno K, Yamamoto C, Yamamoto Y, Saika F, Iwai S, Kobayashi Y, Kiguchi N, Maeda T
- Organizer
  The 1^<st> meeting of the Asian College of Neuropsychopharmacology
- Place of Presentation
  Kyoto
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Involvement of endogenous opioid system in the development of physical dependence on nicotine in mice.2009
- Author(s)
  Kishioka S, Ueno K, Yamamoto C, Maeda T, Kiguchi N, Kobayashi Y, Fukazawa Y
- Organizer
  The International Narcotics Research Conference 2009
- Place of Presentation
  Portland, Oregon
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Adipokines regulate development of neuropathic pain.2009
- Author(s)
  Maeda T, Kishioka S
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Involvement of endogenous opioid system in nicotine-induced antinociception and physical dependence in mice.2009
- Author(s)
  Kobayashi Y, Ueno K, Kiguchi N, Maeda T, Yamamoto C, Kishioka S
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] Effects of peroxisome proliferator-activated receptor gamma agonist on the neuropathic pain induced by partial sciatic nerve ligation in mice.2008
- Author(s)
  Kishioka S, Maeda T, Kiguchi N, Kobayashi Y
- Organizer
  Japan-China Medical Workshop on Drug Discoveries and Therapeutics 2008
- Place of Presentation
  Tokyo
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] The activation of peroxisome proliferator-activated receptor gamma (PPARγ) suppresses the neuropathic pain due to partial sciatic nerve ligation in mice.2008
- Author(s)
  Maeda T, Kishioka S
- Organizer
  XI Workshop on Apoptosis in Biology and Medicine
- Place of Presentation
  Sendai
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20591376
[Presentation] 牛腎ミクロソーム/NADPH反応溶液中のフリーラジカル生成に対するミオグロビン添加の影響2007
- Author(s)
  熊本和正, 平井富弘, 岸岡史郎, 岩橋秀雄
- Organizer
  BMB2007(第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18500519
[Presentation] Identification of 1-Ethoxyethyl Radicals in the Reaction of Ferrous Ions with Serums from Rats Exposed to Diethyl Ether2007
- Author(s)
  Kumamoto K, Hirai T, Kishioka S, Iwahashi H
- Organizer
  The XI International Congress of Toxicology
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-18500519
[Presentation] Identification of a radical formed in the reaction mixture of rat brain homogenate with ferrous ion/ascorbic acid using HPLC-ESR and HPLOESR-MS2006
- Author(s)
  Kumamoto K, Hirai T, Kishioka S, Iwahashi H
- Organizer
  The 13^<th> Congress of the Society for Free Radical Research International
- Place of Presentation
  Davos, Switzerland
- Data Source
  KAKENHI-PROJECT-18500519
[Presentation] Macrophage inflammatory proteins contributing to neuropathic pain were upregulated by histone modifications after peripheral nerve injury
- Author(s)
  Kiguchi N, Kobayashi Y, Kishioka S
- Organizer
  International Symposium for Neurosciences 2013
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 骨髄由来細胞におけるニコチン性アセチルコリン受容体シグナルの神経障害性疼痛改善効果
- Author(s)
  木口倫一、小林悠佳、前田武彦、岸岡史郎
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] IL-4は炎症性マクロファージおよび神経障害性疼痛を抑制する
- Author(s)
  木口倫一、小林悠佳、雑賀史浩、前田武彦、岸岡史郎
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 血管新生マクロファージは末梢神経炎症を伴う神経障害性疼痛に関与する
- Author(s)
  木口倫一、小林悠佳、岸岡史郎
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] ケモカインによる末梢感作と神経障害性疼痛
- Author(s)
  木口倫一、小林悠佳、岸岡史郎
- Organizer
  第1回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 血管新生マクロファージは末梢神経炎症を伴う神経障害性疼痛に関与する
- Author(s)
  木口倫一、小林悠佳、岸岡史郎
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 神経障害性疼痛治療標的としての末梢ニコチン性アセチルコリン受容体
- Author(s)
  岸岡史郎、木口倫一、雑賀史浩、小林悠佳
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 神経障害性疼痛治療標的としての末梢ニコチン性アセチルコリン受容体
- Author(s)
  岸岡史郎、木口倫一、雑賀史浩、小林悠佳
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] Nicotine acts on the bone marrow-derived immune cells and prevents neuropathic pain following peripheral nerve injury
- Author(s)
  Kishioka S, Wakida N, Kobayashi Y, Maeda T, Kiguchi N
- Organizer
  Neuroscience 2012, SfN’s 42nd annual meeting
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 骨髄由来細胞におけるニコチン性アセチルコリン受容体シグナルは神経障害性疼痛を改善する
- Author(s)
  木口倫一、小林悠佳、前田武彦、冨永信太、中村淳、岸岡史郎
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] ケモカインによる末梢感作と神経障害性疼痛
- Author(s)
  木口倫一、小林悠佳、岸岡史郎
- Organizer
  第1回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 骨髄由来細胞におけるニコチン性アセチルコリン受容体シグナルは神経障害性疼痛を改善する
- Author(s)
  木口倫一、小林悠佳、前田武彦、冨永信太、中村淳、岸岡史郎
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 神経障害性疼痛における末梢性VEGFシグナルの関与
- Author(s)
  木口倫一、小林悠佳、門脇友維、雑賀史浩、岸岡史郎
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] マクロファージ炎症性タンパク質は末梢神経炎症を介して神経障害性疼痛を惹起する
- Author(s)
  木口倫一、岸岡史郎
- Organizer
  第34回日本疼痛学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] マクロファージ炎症性タンパク質は末梢神経炎症を介して神経障害性疼痛を惹起する
- Author(s)
  木口倫一、岸岡史郎
- Organizer
  第34回日本疼痛学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] Augmentation of the MIP-2/CXCR2 axis through histone H3 acetylation in injured peripheral nerves facilitates neuropathic pain
- Author(s)
  Kiguchi N, Kobayashi Y, Kishioka S
- Organizer
  Neuroscience 2012, SfN’s 42nd annual meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] マクロファージによる血管新生と神経障害性疼痛
- Author(s)
  岸岡史郎、木口倫一、小林悠佳、門脇友維、和木田直希
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 神経炎症を標的とした神経障害性疼痛の末梢性調節
- Author(s)
  木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第2回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] Novel mediators of peripheral sensitization
- Author(s)
  Kishioka S, Wakida N, Kobayashi Y, Kiguchi N
- Organizer
  NEW TRENDS IN PAIN RESEARCH
- Place of Presentation
  Calabria, Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 神経障害性疼痛における末梢性VEGFシグナルの関与
- Author(s)
  木口倫一、小林悠佳、門脇友維、雑賀史浩、岸岡史郎
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 傷害末梢神経におけるヒストン修飾は神経障害性疼痛を調節する
- Author(s)
  木口倫一、岸岡史郎
- Organizer
  第35回日本疼痛学会
- Place of Presentation
  さいたま
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 神経炎症を標的とした神経障害性疼痛の末梢性調節
- Author(s)
  木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第2回ニューロカンファレンス和歌山
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] マクロファージ由来VEGFは血管新生および神経障害性疼痛に関与する
- Author(s)
  門脇友維、木口倫一、小林悠佳、雑賀史浩、岸岡史郎
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590730
[Presentation] 骨髄由来細胞におけるニコチン性アセチルコリン受容体シグナルの神経障害性疼痛改善効果
- Author(s)
  木口倫一、小林悠佳、前田武彦、岸岡史郎
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24592356
[Presentation] 傷害末梢神経におけるヒストン修飾は神経障害性疼痛を調節する
- Author(s)
  木口倫一、岸岡史郎
- Organizer
  第35回日本疼痛学会
- Place of Presentation
  さいたま
- Data Source
  KAKENHI-PROJECT-24590730

1. KIGUCHI Norikazu (90433341)

# of Collaborated Projects: 10 results

# of Collaborated Products: 106 results
2. MAEDA Takehiko (50271010)

# of Collaborated Projects: 6 results

# of Collaborated Products: 38 results
3. KOBAYASHI Yuka (20511562)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
4. OZAKI Masanobu (30094650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. FUKAZAWA Yohji (70336882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 雑賀史浩 (10644099)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
7. KOBAYASHI Daichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
8. KUMAMOTO Kazumasa (50225231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. IWAHASHI Hideo (50145926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. HIRAI Tomohiro (70020104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. KADOWAKI Yui

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
12. SAKAGUCHI Haruka

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MATSUZAKI Shinsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
14. 西谷友重

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kishioka Shiro 岸岡 史郎

KISHIOKA Shiroh 岸岡 史郎

Research Projects

Research Products

Co-Researchers

Mechanisms-based therapeutic strategies for neuropathic pain through peripheral macrophagesPrincipal Investigator

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Pathogenesis of neuropathic pain due to interaction between peripheral and central sensitization

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Novel therapeutics for macrophage-driven inflammatory diseases via nicotinic acetylcholine receptor signalingPrincipal Investigator

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骨転移痛におけるセマフォリンの病態生理学的役割の解析

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Identification of crosstalk between pathological angiogenesis and neurons in regulating chronic painPrincipal Investigator

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Molecular mechanism of chronic pain via histone-dependent peripheral sensitization

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Study on pathophysiological mechanism underlying leptin-induced exacerbation of neuropathic pain

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Study on neuropathic pain associated with pre-diabetes and obese

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Involvement of opioid system in nicotine and alcohol dependencePrincipal Investigator

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神経因性疼痛増悪因子としてのアディポサイトカインに関する研究

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Detection and identification of lipid-derived radicals formed by myoglobin released from damaged skeletal muscles after excessive exercise

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Ligands for peroxisome proliferaoractivated receptor as possible novel analgesicPrincipal Investigator

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[Book] Chapter 13 PPAR and Pain 852009

Author(s)

Publisher

Kishioka Shiro 岸岡史郎

KISHIOKA Shiroh 岸岡史郎