MAKINO Naoki 牧野直樹

Researcher Number	60157170
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014: 九州大学病院別府病院, 内科, 名誉教授 2011 – 2014: 九州大学, 大学病院, 教授 2013: 九州大学病院, 別府病院, 教授 2008 – 2010: 九州大学, 生体防御医学研究所, 教授 2005 – 2006: 九州大学, 生体防御医学研究所, 教授 … More 1999 – 2003: Medical Institute of Bioregulation Kyushu University Professor, 生体防御医学研究所, 教授 1995 – 1998: 九州大学, 生体防御医学研究所, 助教授 1990 – 1992: Kyushu University, Bioclimatology and Medicine Medical Institute of Bioregulation Associated Professor, 生体防御医学研究所, 助教授 1987 – 1989: 九州大学, 生体防御医学研究所, 講師 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / General internal medicine (including Psychosomatic medicine) / Circulatory organs internal medicine
Keywords	Principal Investigator MMP / PPAR-r / myocardial infarction / matrix metaloproteinase / 心筋梗塞 / 遺伝子治療 / 心筋肥大 / アンギオテンシン転換酵素阻害剤 / 遺伝子発現 / コラーゲン … More / alpha1-adrenoceptors / cardiac regression / cardiac hypertrophy / rat heart / heart sarcolemma / [5-methyl-^3H] nitrendipine binding / calcium ion pump / sodium-calcium ion exchange / 心筋細胞膜 / カルシウム / 膜イオン輸送 / Na^+K^+ーATPase / 膜リン脂質 / Ca^<2+>ポンプ / Na^+ーCa^<2+>交換 / 自然発症型高血圧ラット / 心筋肥大退縮 / ベ-タ-遮断剤 / アルファ-遮断剤 / カテコラミン受容体 / 自然発症高血圧ラット / ラット / 肥大退縮 / 膜脂質代謝 / アドレナリン受容体 / カルシウム代謝 / 圧負荷肥大心 / gene therapy / remodeling / tyrosine phosphorylation / angiogenesis / 血管新生療法 / SiRNA / SHP-1 / 血管内皮増殖因子 / リモデリング / チロシンリン酸化 / 血管新生 / NFκ-B / Cytokines / Brain Natriuretic Peptide / Cardiac Remodeling / TIMP / TNF-alpha / 心筋細胞 / 低酸素 / マトリックスメタロプロテアーゼ / NFk-b / サイトカイン / BNP / 心筋リモデリング / Tissue Necrosis Factor / Myocardial Fibrosis / Extracellular Matrix / メタロプロテアーゼ / TNFα / 心筋線維化 / 細胞外マトリックス / HYPERTROPHY / SHR / GENE THERAPY / ANGIOTENSINOGEN / アンジオテンシノーゲン / アンチセンス / NEBULIN / GENE EXPRESSION / HEART / 心房 / ネブリン / 心臓 / Enalapril / Angiotensin converting enzyme inhibitor / Gene expression / Myocardial damage / Immunohistochemistry / Fibronectin / Collagen, / Cardiomyopathic hamster / フイブロネクチン / コラ-ゲン / 心筋症ハムスタ- / エナラプリル / 免疫組織化学 / 心筋障害 / 免疫細織化学 / フィブロネクチン / 心筋症ハムスター … More Except Principal Investigator MRI / 心筋梗塞 / サイトカイン / 血管内皮細胞 / 老化 / テロメア / Sudden death / Periodic Variation / Bradyarrhythmias / Catecholamine / Acoustic stimuli / 致死性不整脈 / 細胞内Ca蓄積 / 左心房 / ジギタリスリセプター / 細胞膜心室細動 / 多現象記録 / カフェイン / ジギタリス / 不整脈の周期性変動 / 不整脈の自然変動 / カテコラミン / 長時間連続心電図記録 / テレメトリー / Ca拮抗剤 / カテコールアミン / 急死 / 徐脈性不整脈 / 音刺激 / 自然変動 / 不整脈 / Aging / Relaxation time / Muscle / 速筋 / 緩和時間 / 加齢 / 筋肉 / Myocardial infarction / Endothelial cells / Angiogenesis / Apoptosis / Soluble TNF receptor 1 / Tumor necrosis factor / 酸化LDL / TNF-alphaレセプタ-1 / 血管新生 / アポトーシス / soluble TNF receptor 1 / 腫瘍壊死因子(TNF) / AT1 Blocker / MyocarDial Infarction / Collagen / Matrix Metalloproteinase / Extracellular Mtrix / Cardiac Remodeling / ATI拮抗薬 / 心筋再構築 / コラーゲン / マトリックス・メタロプロテアーゼ / 細胞外マトリックス / Rat / Perfused Heart / Freeradical Scavenger / Sodium / Calcium / Free Radical / Cardiac Damage / Reperfusion / 灌流ラット心 / Na^+-K ATPase / 再灌流不整脈 / 心筋カルシウム / 心筋細胞膜 / 膜脂質過酸化 / 潅流ラット心 / 活性酸素 / Na^+ーK ATPaes / ラット心臓 / 活性酸素消去剤 / 腫瘍壊死因子 / インタ-ワイキン1 / 再潅流障害 / ラット / 摘出潅流心 / フリ-ラジカル消去剤 / フリ-ラジカル / カルシウム代謝 / 再潅流不整脈 / 再潅流心筋障害 / 近赤外線レーザー / 心臓局所温熱 / トランスジェニックマウス / ナノテクノロジー / 循環器 / 温熱療法 / 心不全 / 金ナノロッド / 白血球 / 環状DNA / DNA組換え / 慢性疾患 / DNAメチル化 / サブテロメア Less

Targeted heart hyperthermia for heart failure using gold nano-rod
- Principal Investigator
  
  HIGUCHI Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
The evaluation of genomic aging by quantifying telomeric circular DNA in peripheral leukocytes of patients with chronic disease.
- Principal Investigator
  
  MAEDA Toyoki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kyushu University
The relationship between telomere attrition and the subtelomeric methylation of peripheral leukocytes
- Principal Investigator
  
  MAEDA Toyoki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kyushu University
Role of Tyrosine Dephosphorylation on Angiogenesis in Remodeling after Myocardial IschemiaPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERCITY
Matrix Degradative Enzyme Activities on Cardiac Remodeling in Heart FailurePrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Development of new gene therapy for treatment of atherosclerosis using anti-apoptotic genes
- Principal Investigator
  
  SUGANO Masahiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
New approach for evaluating muscle function by using MR imaging
- Principal Investigator
  
  HATAKENAKA Masamitsu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  KYUSHU UNIVERSITY
Regulation of Synthesis and Degradation of Extracellular Matrix in Acute Myocardial InfarctionPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki, 畑知二
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Chronic Effects of Antisense Oligodeoxynucleotides Against Angiotensinogen on Cardiac Remodeling in Spontaneously Hypertensive RatsPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Investigation of Extracellular Matrix Synthesis and Degradation after Myocardial Infarction.
- Principal Investigator
  
  HATA Tomoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
POSITION SPECIFIC GENE EXPRESSION IN HEARTPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
STUDIES OF PATHOPHYSIOLOGICAL AND BIOCHEMICAL ASPECTS ON THE DEVELOPMENT OF CARDIOMYOPATHIC HAMSTERSPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Role of Calcium and Protective Effects on Reperfusion Cardiac Damages
- Principal Investigator
  
  YANAGA Takashi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Sarcolemmal Ion Transport in Pressure Induced Cardiac HypertrophyPrincipal Investigator
- Principal Investigator
  
  MAKINO Naoki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Mechanism of appearance of periodic variation of arrhythmias
- Principal Investigator
  
  TAKASHI YANAGA
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] X-irradiation alters the telomerase activity and the telomere length distribution of cultured human vascular endothelial cells2014
- Author(s)
  Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino
- Journal Title
  
  Appl Cell Biol
  
  Volume: 3
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Vascular endothelial cell surviving through under prolonged elevated temperature shows persistent or transient up-regulation of telomerase and stress-associated proteins2014
- Author(s)
  Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino
- Journal Title
  
  Appl Cell Biol
  
  Volume: 2
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] X-irradiation alters the telomerase activity and the telomere length distribution of cultured human vascular endothelial cells.2014
- Author(s)
  Toyoki Maeda1, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino.
- Journal Title
  
  Appl Cell Biol
  
  Volume: 3 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Vascular endothelial cell surviving through under prolonged elevated temperature shows persistent or transient up-regulation of telomerase and stress-associated proteins.2014
- Author(s)
  Toyoki Maeda1, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino.
- Journal Title
  
  Appl Cell Biol
  
  Volume: 3 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Hyperthermia by bathing in a hot spring improves cardiovascular functions and reduces the production of inflammatory cytokines in patients with chronic heart failure.2013
- Author(s)
  Oyama J, Kudo Y, Maeda T, Node K, Makino N.
- Journal Title
  
  Heart Vessels.
  
  Volume: 28 Issue: 2 Pages: 173-178
- DOI
  10.1007/s00380-011-0220-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Analysis of telomere length and subtelomeric methylation of circulating leucocytes in female patients with Alzheimer's disease2013
- Author(s)
  J-Z. Guan, T. Maeda N. Makino
- Journal Title
  
  Aging Clin Exp Res
  
  Volume: 25 Pages: 17-23
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Telomerase activity and telomere length distribution in vascular endothelial cell in a short-term culture under the presence of hydrogen peroxide2013
- Author(s)
  Maeda T, Jing-Zhi Guan, Koyanagi M, Makino N
- Journal Title
  
  Geriatrics and Gerontology International
  
  Volume: 13 Pages: 774-782
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition2013
- Author(s)
  Maeda T, G. Jing-Zhi, Koyanagi M Makino N
- Journal Title
  
  Aging Clin Exp Res
  
  Volume: 25 Pages: 231-238
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition.2013
- Author(s)
  Maeda T, Guan JZ, Koyanagi M, Makino N.
- Journal Title
  
  Aging Clin Exp Res.
  
  Volume: 25 Issue: 3 Pages: 231-238
- DOI
  10.1007/s40520-013-0045-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885, KAKENHI-PROJECT-23591083
[Journal Article] Telomerase activity and telomere length distribution in vascular endothelial cells in a short-term culture under the presence of hydrogen peroxide.2013
- Author(s)
  Maeda T, Guan JZ, Koyanagi M, Makino N.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 13 Issue: 3 Pages: 774-782
- DOI
  10.1111/j.1447-0594.2012.00936.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Hyperthermia by bathing in a hot spring improves the cardiovascular functions and reduces the production of inflammatory cytokines in patients with chronic heart failure2013
- Author(s)
  Jun-ichi Oyama, Yoshihiro Kudo, Toyoki Maeda, Koichi Node, Naoki Makino
- Journal Title
  
  Heart and Vessels
  
  Volume: 13 Pages: 774-782
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Analysis of telomere length and subtelomeric methylation of circulating leukocytes in women with Alzheimer's disease.2013
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino N.
- Journal Title
  
  Aging Clin Exp Res.
  
  Volume: 25 Issue: 1 Pages: 17-23
- DOI
  10.1007/s40520-013-0006-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Different levels of hypoxia regulate telomere length and telomerase activity2012
- Author(s)
  Jing-Zhi Guan, Wei-Ping Guan, Toyoki Maeda, Naoki Makino
- Journal Title
  
  Aging Clin Exp Res
  
  Volume: 24 Pages: 213-217
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Continuous Positive Airway Pressure Therapy Improves Vascular Dysfunction and Decreases Oxidative Stress in Patients With the Metabolic Syndrome and Obstructive Sleep Apnea Syndrome2012
- Author(s)
  Oyama JI, Yamamoto H, Maeda T, Ito A, Node K, Makino N
- Journal Title
  
  Clin Cardiol
  
  Volume: 35 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease.2012
- Author(s)
  Maeda T, Guan JZ, Koyanagi M, Higuchi Y, Makino N.
- Journal Title
  
  Journal of Neurogenetics
  
  Volume: 26 Issue: 2 Pages: 245-251
- DOI
  10.3109/01677063.2011.651665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885, KAKENHI-PROJECT-23591083
[Journal Article] Alteration of telomere length and subtelomeric methylation in human endothelial cell under different levels of hypoxia.2012
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino N.
- Journal Title
  
  Archives of Medical Research
  
  Volume: 43 Issue: 1 Pages: 15-20
- DOI
  10.1016/j.arcmed.2012.02.001
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-alpha overexpression2012
- Author(s)
  Higuchi Y, Kubota T, Koyanagi M, Maeda T, Feldman AM, Makino N.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 302(11) Issue: 11 Pages: H2352-H2362
- DOI
  10.1152/ajpheart.01026.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591083, KAKENHI-PROJECT-24591098
[Journal Article] Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats.2012
- Author(s)
  Oyama J, Maeda T, Sasaki M, Higuchi Y, Node K, Makino N.
- Journal Title
  
  American Journal of Physiology Heart Circulation Physiology
  
  Volume: 302 Issue: 10 Pages: 2092-2101
- DOI
  10.1152/ajpheart.00225.2011
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Radiation- associated telomere length changes of peripheral leukocytes of inpatients with cancer International2012
- Author(s)
  Toyoki Maeda, Katsumasa Nakamura, Kazushige Atsumi, Masakazu Hirakawa, Yasuko Ueda, Naoki Makino
- Journal Title
  
  Journal of Radiation Biology
  
  Volume: 89 Pages: 106-109
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease.2012
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino N.
- Journal Title
  
  Gerontology
  
  Volume: 58 Issue: 1 Pages: 62-69
- DOI
  10.1159/000327821
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Alteration of telomere length and subtelomeric methylation in human endothelial cell under different levels of hypoxia2012
- Author(s)
  Jing-Zhi Guan, Wei-Ping Guan, Toyoki Maeda, Naoki Makino
- Journal Title
  
  Archives of Medical Research
  
  Volume: 43 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats2012
- Author(s)
  Oyama JI, Maeda T, Sasaki M, Higuchi Y, Node K, Makino N
- Journal Title
  
  Am J Physiol-Heart Circ Physiol
  
  Volume: 302
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Continuous positive airway pressure therapy improves vascular dysfunction and decreases oxidative stress in patients with the metabolic syndrome and obstructive sleep apnea syndrome.2012
- Author(s)
  Oyama J, Yamamoto H, Maeda T, Ito A, Node K, Makino N.
- Journal Title
  
  Clinical Cardiolology
  
  Volume: 35 Issue: 4 Pages: 231-236
- DOI
  10.1002/clc.21010
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] The Subtelomere of Short Telomeres is Hypermethylated in Alzheimer's Disease.2012
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino N.
- Journal Title
  
  Aging and Disease
  
  Volume: 3 Pages: 164-170
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Upregulation of Anticoagulant Proteins, Protein S and Tissue Factor Pathway Inhibitor, in the Mouse Myocardium with Cardio-Specific TNF- x03B1; Overexpression2012
- Author(s)
  Yosihiro Higuchi, Masamichi Koyanagi, Toru Kubota, Toyoki Maeda, Arthur Feldman, Naoki Makino
- Journal Title
  
  Am J Physiol-Heart Circ Physiol
  
  Volume: 302
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Different levels of hypoxia regulate telomere length and telomerase activity.2012
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino.
- Journal Title
  
  Aging Clin Exp Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Different levels of hypoxia regulate telomere length and telomerase activity.2012
- Author(s)
  Guan JZ, Guan WP, Maeda T, Makino N.
- Journal Title
  
  Aging and Clinical Experimental Research
  
  Volume: 24 Pages: 213-217
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] The gender-related alterations in the telomere length and subtelomeric methylation status in patients with Parkinson's disease2012
- Author(s)
  Maeda T, Jing-Zhi Guan, Koyanagi M, Makino N
- Journal Title
  
  Ageing Res
  
  Volume: 4 Pages: 61-66
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease2012
- Author(s)
  Toyoki Maeda, Jing Zhi Guan, Masamichi Koyanagi, Yoshihiro Higuchi, Naoki Makino
- Journal Title
  
  Neurogenetics
  
  Volume: 26 Pages: 245-251
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Antioxidant Therapy Attenuates Myocardial Telomerase Activity Reduction in Superoxide Dismutase-Deficient Mice2011
- Author(s)
  Makino N, Maeda T, Oyama JI, Sasaki M, Higuchi Y, Mimori K, Shimizu T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 50 Pages: 670-677
- NAID
  120004951631
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] The effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease2011
- Author(s)
  Jing-Zhi Guan, Wei-Ping Guan, Toyoki Maeda, Naoki Makino
- Journal Title
  
  Gerontology
  
  Volume: 58 Pages: 62-69
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] The correlation between clinical laboratory data and telomeric status of male patients with metabolic disorders and no clinical history of vascular events.2011
- Author(s)
  T Maeda, JI Oyama, M Koyanagi, Y Higuchi, M Sasaki, K Mimori, T Arima, N Makino
- Journal Title
  
  Aging Male 14
  
  Pages: 21-26
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension.2011
- Author(s)
  T Maeda, JI Oyama, M Sasaki, T Arima, N Makino
- Journal Title
  
  J Nutr Health Aging 15
  
  Pages: 240-244
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析.2011
- Author(s)
  前田豊樹,小柳雅孔,尾山純一,樋口義洋,牧野直樹
- Journal Title
  
  適応医学
  
  Volume: 14 Pages: 50-59
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析2011
- Author(s)
  前田豊樹, 小柳雅孔, 尾山純一, 樋口義洋, 牧野直樹
- Journal Title
  
  適応医学 14
  
  Pages: 50-59
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension.2011
- Author(s)
  T Maeda, J-I Oyama, M Sasaki, T Arima, N Makino.
- Journal Title
  
  J Nutr Health Aging
  
  Volume: 15 Pages: 240-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The subtelomere of short telomeres is hypermethylated in Alzheimer's disease2011
- Author(s)
  Jing-Zhi Guan, Toyoki Maeda, Naoki Makino
- Journal Title
  
  Aging and Disease
  
  Volume: 3 Pages: 164-170
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] Telomerase inhibition promotes an initial step of cell differentiation of primate embryonic stem cell2011
- Author(s)
  Maeda T, Kurita R, Yokoo T, Tani K, Makino N
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 407 Pages: 491-494
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析2011
- Author(s)
  前田豊樹,小柳雅孔,尾山純一,樋口義洋,牧野直樹
- Journal Title
  
  適応医学
  
  Volume: 14 Pages: 50-59
- Data Source
  KAKENHI-PROJECT-23590885
[Journal Article] 種々の臨床検査値と末梢血白血球テロメア関連パラメータとの連関の解析2010
- Author(s)
  前田豊樹, 小柳雅孔, 尾山純一, 樋口義洋, 牧野直樹
- Journal Title
  
  適応医学
  
  Volume: 14 Pages: 50-59
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Green Tea Catechins Improve Human Forearm Endothelial Dysfunction and Have Antiatherosclerotic Effects in Smokers.2010
- Author(s)
  JI.Oyama, T.Maeda, K.Kouzuma, R.Ochiai, I.Tokimitsu, Y.Higuchi, M.Sugano, N.Makino
- Journal Title
  
  Circ J. 74
  
  Pages: 578-588
- NAID
  10025943880
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The physical ability of Japanese female elderly with cerebrovascular disease correlates to the telomere length and subtelomeric methylation status in their peripheral blood leukocytes.2010
- Author(s)
  T.Maeda, JI.Oyama, Y.Higuchi, Y.Nishiyama, Y.Kudo, T Yamori, T.Nakazono, T.Arima, K.Mimori, N.Makino
- Journal Title
  
  Gerontology 57
  
  Pages: 137-143
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Green tea catechins improve human forearm vascular function and have potent anti-inflammatory and anti-apoptotic effects in smokers.2010
- Author(s)
  J-I Oyama, T Maeda, M Sasaki, K Kozuma, R Ochiai, I Tokimitsu, S Taguchi, Y Higuchi, N Makino N.
- Journal Title
  
  Intern Med.
  
  Volume: 49 Pages: 2553-2559
- NAID
  130000413399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The physical ability of elderly female Japanese patients with cerebrovascular disease correlates with the telomere length in their peripheral blood leukocytes.2010
- Author(s)
  T Maeda, J-I Oyama, M Sasaki, Y Nishiyama, Y Kudo, T Yamori, T Nakazono, T Arima, N Makino.
- Journal Title
  
  Aging Clin Exp Res
  
  Volume: 23 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The physical ability of Japanese female elderly with cerebrovascular disease correlates to the telomere length and subtelomeric methylation status in their peripheral blood leukocytes.2010
- Author(s)
  T Maeda, J-I Oyama, Y Higuchi, Y Nishiyama, Y Kudo, T Yamori, T.Nakazono, T.Arima, K Mimori, N.Makino.
- Journal Title
  
  Gerontology
  
  Volume: 57 Pages: 137-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 女性高血圧患者における血液検査値と末梢血テロメア長の相関について2010
- Author(s)
  前田豊樹、牧野直樹
- Journal Title
  
  日本老年医学会雑誌 47
  
  Pages: 573-577
- NAID
  10028123522
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 高血圧患者におけるアムロジピン錠「EMEC」の臨床的検討2010
- Author(s)
  前田豊樹、牧野直樹
- Journal Title
  
  Progress in Medicine
  
  Volume: 30 Pages: 3143-3152
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo.2010
- Author(s)
  JI.Oyama, S.Satoh, N.Suematsu, T.Kadokami, T.Maeda, M.Sugano, N.Makino
- Journal Title
  
  Heart Vessels 25
  
  Pages: 379-385
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The correlation between the telomeric parameters and the clinical laboratory data in the patients with brain infarct and metabolic disorders.2010
- Author(s)
  T.Maeda, JI.Oyama, Y.Higuchi, T.Arima, K.Mimori, N.Makino
- Journal Title
  
  J Nutr Health Aging 14
  
  Pages: 793-797
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The correlation between clinical laboratory data and telomeric status of male patients with metabolic disorders and no clinical history of vascular events.2010
- Author(s)
  T Maeda, J-I Oyama, M Koyanagi, Y Higuchi, M Sasaki, K Mimori, T Arima, N Makino
- Journal Title
  
  Aging Male
  
  Volume: 14 Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 高血圧患者におけるアムロジピン錠「EMEC」の臨床的検討2010
- Author(s)
  前田豊樹, 牧野直樹
- Journal Title
  
  Prog Med. 30
  
  Pages: 3143-3152
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Green tea catechins improve human forearm vascular function and have potent anti-inflammatory and anti-apoptotic effects in smokers.2010
- Author(s)
  JI Oyama, T Maeda, M Sasaki, K Kozuma, R Ochiai, I Tokimitsu, S Taguchi, Y Higuchi, N Makino
- Journal Title
  
  Intern Med. 49
  
  Pages: 2553-2559
- NAID
  130000413399
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Antioxidant Therapy Attenuates Myocardial Telomerase Activity Reduction in Superoxide Dismutase-Deficient Mice.2010
- Author(s)
  N Makino, T Maeda T, JI Oyama, M Sasaki, Y Higuchi, K Mimori, T Shimizu
- Journal Title
  
  J Mol Cell Cardiol. 50
  
  Pages: 670-677
- NAID
  120004951631
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 女性高血圧患者における血液検査値と末梢血テロメア長の相関について2010
- Author(s)
  前田豊樹、牧野直樹
- Journal Title
  
  日本老年医学会雑誌
  
  Volume: 472 Pages: 573-577
- NAID
  10028123522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The correlation between the telomeric parameters and the clinical laboratory data in the patients with brain infarct and metabolic disorders.2010
- Author(s)
  T Maeda, J-I Oyama, Y Higuchi, T Arima, K Mimori, N Makino.
- Journal Title
  
  J Nutr Health Aging
  
  Volume: 14 Pages: 793-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Telomere biology in cardiovascular disease - role of insulin sensitivity in diabetic hearts.2010
- Author(s)
  N Makino, M Sasaki, T Maeda, K Mimori
- Journal Title
  
  Exp Clin Cardiol. 15
  
  Pages: 128-133
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo.2010
- Author(s)
  J-I Oyama, S Satoh, N Suematsu, T Kadokami, T Maeda, M Sugano, N Makino.
- Journal Title
  
  Heart Vessels
  
  Volume: 25 Pages: 379-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Green Tea Catechins Improve Human Forearm Endothelial Dysfunction and Have Antiatherosclerotic Effects in Smokers.2010
- Author(s)
  J-I Oyama, T.Maeda, K.Kouzuma, R.Ochiai, I.Tokimitsu, Y Higuchi, M Sugano, N Makino
- Journal Title
  
  Circ J.
  
  Volume: 74 Pages: 578-588
- NAID
  10025943880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Antioxidant Therapy Attenuates Myocardial Telomerase Activity Reduction in Superoxide Dismutase-Deficient Mice.2010
- Author(s)
  N Makino, T Maeda, J-I Oyama, M Sasaki, Y Higuchi, K Mimori, T Shimizu.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 50 Pages: 670-677
- NAID
  120004951631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Telomere biology in cardiovascular disease-role of insulin sensitivity in diabetic hearts.2010
- Author(s)
  N Makino, M Sasaki, T Maeda, K Mimori.
- Journal Title
  
  Exp Clin Cardiol.
  
  Volume: 15 Pages: 128-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Improving insulin sensitivity via activation of PPAR-gamma increases telomerase activity in the heart of OLETF rats2009
- Author(s)
  牧野直樹, 前田豊樹, 尾山純一, 樋口義洋, 三森功士
- Journal Title
  
  Am J Physiol Heart Circ Physiol 297
  
  Pages: 2188-2195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-associated alteration of subtelomeric methylation in Parkinson's disease.2009
- Author(s)
  T Maeda, JZ Guan, JI Oyama, Y Higuchi, N Makino
- Journal Title
  
  J Gerontol A Biol Sci and Med Sci 64
  
  Pages: 949-955
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Improving insulin sensitivity via activation of PPAR-gamma increases telomerase activity in the heart of OLETF rats.2009
- Author(s)
  N.Makino, T.Maeda, JI Oyama, Y.Higuchi, K Mimori
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 297
  
  Pages: 2188-2195
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 老化促進に作用する環境因子2009
- Author(s)
  牧野直樹、前田豊樹、尾山純一、樋口義洋
- Journal Title
  
  日本臨床 67
  
  Pages: 1332-1336
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Age-related changes in subtelomeric methylation in the normal Japanese population2009
- Author(s)
  前田豊樹, 管静芝, 尾山純一, 樋口義洋, 牧野直樹
- Journal Title
  
  J Gerontol A Biol Sci Med Sci. 64
  
  Pages: 426-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Age-related changes in subtelomeric methylation in the normal Japanese population.2009
- Author(s)
  Maeda T, Guan JZ, Oyama J, Higuchi Y, Makino N.
- Journal Title
  
  The Journals of Gerontology. Seies A, Biological Sciences and Medical Sciences. 64
  
  Pages: 426-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-associated alteration of subtelomeric methylation in Parkinson's disease2009
- Author(s)
  前田豊樹, 管静芝, 尾山純一, 樋口義洋, 牧野直樹
- Journal Title
  
  J Gerontol A Biol Sci Med Sci. 64
  
  Pages: 949-955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] TNF-alpha employs a protein-tyrosine phosphatase to inhibit activation of hepatocyte growth factor receptor and hepatocyte growth factorinduced endothelial cell proliferation.2009
- Author(s)
  Sugano M, Iwasaki Y, Abe M, Maeda T, Tsuchida K, Makino N.
- Journal Title
  
  Molecular and Cellular Biochemistry 322
  
  Pages: 113-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Age-related changes in subtelomeric methylation in the normal Japanese population.2009
- Author(s)
  T Maeda, JZ Guan, JI Oyama, Y Higuchi, N Makino
- Journal Title
  
  J Gerontol A Biol Sci and Med Sci 64
  
  Pages: 426-434
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Diagonal earlobe crease are associated with shorter telomere in male Japanese patients with metabolic syndrome.2009
- Author(s)
  Higuchi Y, Maeda T, Guan JZ, Oyama J, Sugano M, Makino N
- Journal Title
  
  Circulation Journal 73
  
  Pages: 274-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-related alterations of subtelomeric methylation in sarcoidosis patients2009
- Author(s)
  前田豊樹, 管静芝, 尾山純一, 樋口義洋, 牧野直樹
- Journal Title
  
  J Gerontol A Biol Sci Med Sci. 64
  
  Pages: 752-760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] 老化促進に作用する環境因子2009
- Author(s)
  牧野直樹, 前田豊樹, 尾山純一, 樋口義洋
- Journal Title
  
  日本臨床 67
  
  Pages: 1332-1336
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-associated alteration of subtelomeric methylation in Parkinson's disease2009
- Author(s)
  Maeda T, Guan JZ, Oyama J, Higuchi Y, Makino N.
- Journal Title
  
  The Journals of Gerontology. Seies A, Biological Sciences and Medical Sciences. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Diagonal Earlobe Creases Are Associated with a Shorter Telomere Length in Male Japanese Patients with Metabolic Syndrome2009
- Author(s)
  Y Higuchi, T Maeda, JI Oyama, N Makino
- Journal Title
  
  - A Pilot Study- Circ J 73
  
  Pages: 274-279
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-related alterations of subtelomeric methylation in sarcoidosis patients.2009
- Author(s)
  T Maeda, JZ Guan, JI Oyama, Y Higuchi, N Makino
- Journal Title
  
  J Gerontol A Biol Sci and Med Sci 64
  
  Pages: 752-760
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] TNF-alpha employs a protein-tyrosine phosphatase to inhibit activation of hepatocyte growth factor receptor and hepatocyte growth factor-induced endothelial cell2009
- Author(s)
  M Sugano, Y Iwasaki, M Abe, T Maeda, K Tsuchida, N Makino
- Journal Title
  
  proliferation. Mol Cell Biochem. 322
  
  Pages: 113-117
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Aging-related alterations of subtelomeric methylation in sarcoidosis patients2009
- Author(s)
  Maeda T, Guan JZ, Oyama J, Higuchi Y, Makino N.
- Journal Title
  
  The Journals of Gerontology. Seies A, Biological Sciences and Medical Sciences. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] An analysis of the telomere length distribution in Parkinson's disease patients.2008
- Author(s)
  JZ Guan, T Maeda, M Sugano, J Oyama, Y Higuchi, N Makino
- Journal Title
  
  J Gerontol A Biol Sci and Med Sci 63
  
  Pages: 467-473
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] A percentage analysis of the telomere length in Parkinson's disease patients.2008
- Author(s)
  Guan JZ, Maeda T, Sugano M, Oyama J, Higuchi Y, Suzuki TMakino N.
- Journal Title
  
  The Journals of Gerontology. Seies A, Biological Sciences and Medical Sciences. 63
  
  Pages: 467-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] SiRNA targeting SHP-1 accelerates angiogenesis in a rat model of hindlimb ischemia.) : 33-9.2007
- Author(s)
  Sugano M, Tsuchida K. Maeda T, Makino N
- Journal Title
  
  Atherosclerosis. 191
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Transient receptor potential (TRP) protein 7 acts as a G protein-activated Ca2+ channel mediating angiotensin II-induced myocardial apoptosis.2007
- Author(s)
  Satoh S, Tanaka H, Ueda Y, Oyama J, Sugano M, Sumimoto H, Mori Y, Makino N
- Journal Title
  
  Mol Cell Biochem. 294
  
  Pages: 205-215
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] SiRNA targeting SHP-1 accelerates angiogenesis in a rat model of hindlimb ischemia.) : 33-9.2007
- Author(s)
  Sugano M, Tsuchida K, Maeda T, Makino N
- Journal Title
  
  Atherosclerosis. 191
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Transient receptor potential (TRP) protein 7 acts as a G protein-activated Ca2+ channel mediating angiotensin II- induced myocardial apoptosis.2007
- Author(s)
  Satoh S, Tanaka H, Ueda Y, Oyama J, Sugano M, Sumimoto H, Mori Y, Makino N
- Journal Title
  
  Mol Cell Biochem. 294
  
  Pages: 205-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Transient receptor potential (TRP) protein 7 acts as a G protein-activated Ca2+channel mediating angiotensin II-induced myocardial apoptosis.2007
- Author(s)
  Satoh S, Tanaka H, Ueda Y, Oyama J, Sugano M, Sumimoto H, Mori Y, Makino N
- Journal Title
  
  Mol Cell Biochem. 294
  
  Pages: 205-215
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] SiRNA targeting SHP-l accelerates angiogenesis in a rat model of hindlimb ischemia.2007
- Author(s)
  Sugano M, Tsuchida K, Maeda T, Makino N
- Journal Title
  
  Atherosclerosis. 191
  
  Pages: 33-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia.2006
- Author(s)
  Makino N, Sugano M, Satoh S, Oyama J, Maeda T.
- Journal Title
  
  Cell Biochem Biophys. 44
  
  Pages: 65-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Somatic DNA recombination in a mouse genomic region, BC-1, in brain and non-brain tissue.2006
- Author(s)
  Maeda T, Mizuno R, Sugano M, Satoh S, Oyama J, Sakoda S, Suzuki T, Makino N
- Journal Title
  
  Can J Physiol Phafmacol. 84
  
  Pages: 443-449
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia.2006
- Author(s)
  Makino N, Sugano M, Satoh S, Oyama J, Maeda T
- Journal Title
  
  Cell Biochem Biophys. 44
  
  Pages: 65-71
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Somatic DNA recombination in a mouse genomic region, BC-1,in brain and non-brain tissue.2006
- Author(s)
  Maeda T, Mizuno R, Sugano M, Satoh S, Oyama J, Sakoda S, Suzuki T, Makino N
- Journal Title
  
  Can J Physiol Pharmacol. 84
  
  Pages: 443-449
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia.2006
- Author(s)
  Makino N, Sugano M, Satoh S, Oyama J, Maeda T.
- Journal Title
  
  Cell Biochem Biophys 44(1)
  
  Pages: 65-71
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Somatic DNA recombination in the brain.2006
- Author(s)
  Maeda T, Sakoda S, Suzuki T, Makino N.
- Journal Title
  
  Can J Physiol Pharmacol 84
  
  Pages: 319-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Somatic DNA recombination in a mouse genomic region, BC-l, in brain and nonbrain tissue.2006
- Author(s)
  Maeda T, Mizuno R, Sugano M, Satoh S, Oyama J, Sakoda S, Suzuki T, Makino N
- Journal Title
  
  Can J Physiol Pharmacol. 84
  
  Pages: 443-449
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Somatic DNA recombination in the brain.2006
- Author(s)
  Maeda T, Sakoda S, Suzuki T, Makino N
- Journal Title
  
  Can J Physiol Pharmacol 84
  
  Pages: 319-324
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuietic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia.2006
- Author(s)
  Makino N, Sugano M, Satoh S, Oyama J, Maeda T.
- Journal Title
  
  Cell Biochem Biophys. 44
  
  Pages: 65-71
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] High serum TNF-alpha level in Type 2 diabetic patients with microangiopathy is associated with eNOS down-regulation and apoptosis in endothelial cells2005
- Author(s)
  Makino N, Maeda T, Sugano M, Satoh S, Watanabe R, Abe N
- Journal Title
  
  J Diabetes Complications. 19(6)
  
  Pages: 347-355
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] RNA interference targeting SHP-1 attenuates myocardial infarction in rats.2005
- Author(s)
  Sugano M, Tsuchida K, Hata T, Makino N.
- Journal Title
  
  FASEB J. 19(14)
  
  Pages: 2054-2056
- Data Source
  KAKENHI-PROJECT-17590746
[Journal Article] The effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease.
- Author(s)
  JZ Guan, WP Guan, T Maeda, N Makino
- Journal Title
  
  Gerontology. in press.
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease.
- Author(s)
  JZ Guan, WP Guan, T Maeda, N Makino
- Journal Title
  
  Gerontology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Telomerase inhibition promotes an initial step of cell differentiation of primate embryonic stem cell
- Author(s)
  T Maeda, R Kurita, T Yokoo, K Tani, N Makino.
- Journal Title
  
  Biochem.Biophys.Res.Commun
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] The physical ability of elderly female Japanese patients with cerebrovascular disease correlates with the telomere length in their peripheral blood leukocytes.
- Author(s)
  T.Maeda, JI Oyama, M.Sasaki, Y.Nishiyama, Y.Kudo, T.Yamori, T.Nakazono, T.Arima, N.Makino
- Journal Title
  
  Aging Clin Exp Res. in press.
- Data Source
  KAKENHI-PROJECT-20590703
[Journal Article] Telomerase inhibition promotes an initial step of cell differentiation of primate embryonic stem cell.
- Author(s)
  T Maeda, R Kurita, T Yokoo, K Tani, N Makino
- Journal Title
  
  Biochem.Biophys.Res.Commun. in press.
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] Thrombomodulin Alpha Improved the Cardiac Function but not Hypertrophy in a Transgenic Mouse Model of Inflammatory Cardiomyopathy2013
- Author(s)
  Higuchi Y, Koyanagi M, Kubota T, Feldman AM, and Makino N.
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24591098
[Presentation] 心エコー検査による心機能評価と白血球テロメア長の相関について2013
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第23回日本老年医学会九州地方会
- Place of Presentation
  福岡
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] アルツハイマー病女性患者における末梢白血球テロメア長の変化について2012
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第54回日本老年医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] 鉱泥浴治療効果の客観的指標の探索2012
- Author(s)
  前田豊樹、工藤義弘、西山保弘、牧野直樹
- Organizer
  第77回に本温泉気候物理学会
- Place of Presentation
  仙北
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] パーキンソン病女性患者における末梢白血球テロメア長の変化について2012
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第22回日本老年医学会九州地方会
- Place of Presentation
  佐賀
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] 鉱泥浴治療効果の客観的指標の探索2012
- Author(s)
  前田豊樹、工藤義弘、西山保弘、牧野直樹
- Organizer
  第77回日本温泉気候物理学会
- Place of Presentation
  仙北
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] 外来男性生活習慣病患者における臨床検査値と末梢白血球テロメア長の相関の検討2011
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第21回日本老年医学会九州地方会
- Place of Presentation
  福岡
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 外来男性生活習慣病患者における各種臨床検査値と末梢血白血球テロメア長関連パラメータについて2011
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23590885
[Presentation] 高血圧治療中女性患者における各種臨床検査値と末梢血白血球テロメア長の相関の検討2010
- Author(s)
  前田豊樹, 牧野直樹
- Organizer
  第20回日本老年医学会九州地方会
- Place of Presentation
  熊本
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 療養病床における女性脳卒中入院患者の身体機能と末梢血白血球テロメア長関連パラメータの相関について2010
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第52回日本老年医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 女性高血圧患者における各種臨床検査値と末梢血白血球テロメア長の相関の検討2010
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第19回日本老年医学会九州地方会
- Place of Presentation
  熊本
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 高血圧治療中女性患者における各臨床検査値と末梢血白血球テロメア長の相関の検討2010
- Author(s)
  前田豊樹、尾山純一、樋口義洋、牧野直樹
- Organizer
  第107回日本内科学会総会・講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 療養病床高齢入院患者における種々の臨床検査値と末梢血白血球テロメア長の相関について2009
- Author(s)
  前田豊樹, 牧野直樹
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] 療養病床入院患者末梢血白血球テロメア長の解析2009
- Author(s)
  前田豊樹, 牧野直樹
- Organizer
  第18回日本老年医学会九州地方会
- Place of Presentation
  宮崎(宮崎大学医学部)
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] Telomeric and subtelomeric structural change with aging in chronically ill patients2009
- Author(s)
  前田豊樹, 尾山純一, 樋口義洋, 牧野直樹
- Organizer
  XIXth IAGG World Congress of gerontology and geriatrics
- Place of Presentation
  Paris
- Year and Date
  2009-07-06
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] ゲノムDNAの加齢性変化と疾病2008
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第12回日本適応医学会シンポジゥム
- Place of Presentation
  別府
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590703
[Presentation] サブテロメア領域のメチル化の加齢性変化について2008
- Author(s)
  前田豊樹、牧野直樹
- Organizer
  第18回日本老年医学会九州地方会
- Place of Presentation
  福岡
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-20590703

1. YANO Kenichi (60230281)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. HATA Tomoji (90198739)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MAEDA Toyoki (30264112)

# of Collaborated Projects: 4 results

# of Collaborated Products: 113 results
4. OYAMA Junichi (30359939)

# of Collaborated Projects: 3 results

# of Collaborated Products: 49 results
5. KOYANAGI Masamichi (00325474)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
6. YANAGA Takashi (80038702)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HATAKENAKA Masamitu (40253413)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HIGUCHI Yoshihiro (40404032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
9. SUGANO Masahiro (20206395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. NIIDOME Takuro (20264210)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. MATSUI Hirosuke (10284572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SATOH Shinji (60274445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOSHIMITU Kengo (20274467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ADACHI Toshisada (10335979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YUHEI ICHIMARU (70038909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOSHIDA Satoshi (50158440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 安藤洋志 (80301349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 増田康治 (10037377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大塚誠 (60203840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 門上俊明 (40335980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 上野照紀 (10117070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TSUCHIDA Keiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MATSUTOMO Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HIRAYAMA Hiroyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MAKINO Naoki 牧野 直樹

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Role of Tyrosine Dephosphorylation on Angiogenesis in Remodeling after Myocardial IschemiaPrincipal Investigator

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Matrix Degradative Enzyme Activities on Cardiac Remodeling in Heart FailurePrincipal Investigator

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Regulation of Synthesis and Degradation of Extracellular Matrix in Acute Myocardial InfarctionPrincipal Investigator

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Chronic Effects of Antisense Oligodeoxynucleotides Against Angiotensinogen on Cardiac Remodeling in Spontaneously Hypertensive RatsPrincipal Investigator

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POSITION SPECIFIC GENE EXPRESSION IN HEARTPrincipal Investigator

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STUDIES OF PATHOPHYSIOLOGICAL AND BIOCHEMICAL ASPECTS ON THE DEVELOPMENT OF CARDIOMYOPATHIC HAMSTERSPrincipal Investigator

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Sarcolemmal Ion Transport in Pressure Induced Cardiac HypertrophyPrincipal Investigator

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MAKINO Naoki 牧野直樹