SHIMADA Nobuko 島田信子

… Alternative Names

AHIMADA Nobuko 島田信子

Less

Researcher Number	60158962
External Links
Affiliation (based on the past Project Information) *help	2009: 東京都高齢者研究財団, 助手 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 助手 2007 – 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 助手 2000 – 2001: (財)東京都老人総合研究所, 遺伝子情報部門, 助手 2000: 東京都老人総合研究所, 遺伝子情報部門, 助手 … More 1999 – 2000: 財団法人東京都老人総合研究所, 遺伝子情報部門, 助手 1998: 財団法人, 東京都老人総合研究所・遺伝子情報部門, 助手 1993: (財)東京都老人総合研究所, 分子生物学部門, 助手 1993: (財)東京都老人総合研究所, 分子生物部門, 助手 1992 – 1993: 東京都老人総合研究所, 分子生物学部門, 助手 1991: (財)東京都老人総合研究所, 分子生物学部門, 助手 1987 – 1988: Tokyo Metropolitan Institute of Gerontology, Dept. Biochemistry, 生化学部, 助手 1986: (財)東京都老人総合研究所生化学部, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Eating habits, studies on eating habits / Biological pharmacy Except Principal Investigator Biological pharmacy / Experimental pathology / Pathological medical chemistry / Functional biochemistry / 物質生物化学 / General medical chemistry
Keywords	Principal Investigator PC12D / PACAP / 呼吸器 / 肺 / COPD / ビタミンC / 老化 / 肺気腫 / 喫煙 / 酸化ストレス … More / NDPキナーゼ / アデニル酸シクラーゼ / G蛋白 / NDPK / 三量体G蛋白 / cAMP / トランスフェクション / NDP kinase / adenylate cyclase / G-protein … More Except Principal Investigator nm23 / アイソフォーム / NDPキナーゼ / 細胞増殖 / ヌクレオシドニリン酸(NDP)キナーゼ / 細胞分化 / がん転移抑制 / シグナル伝達 / NDP kinase / Cell growth / NDPキナ-ゼ / cDNA / アイソフォ-ム / 遺伝子単離 / 蛋白一次構造 / 遺伝子構造 / 遺伝子発現 / 臓器・細胞特異的発現 / がん転移 / ヌクレオシド二リン酸キナーゼ / 転写開始点多型性 / RACE法 / コアプロモーター / CATアッセイ / 免疫染色 / タンパク質一次構造 / 遺伝子 / 分化 / 培養細胞 / Nm23 / Defferentiation / 酵素活性 / PC12細胞 / 神経突起形成 / NGF / dbcAMP / Signal transduction / Differentiation / Metastasis suppressor / ヌクレオシドニリン酸キナーゼ / アデニル酸シクラーゼ / GTP結合タンパク質(Gs) / ホルモン / グアニンヌクレオチド / 細胞膜結合性酵素 / GDPGTP / 細胞膜 / Nucleoside diphosphate kinase / Adenylate cyclase / GTP-binding protein(Gs) / Hormone / Guanine nucleotide Less

ビタミンCの体内動態及びビタミンCと骨粗鬆症に関する包括的研究Principal Investigator
- Principal Investigator
  
  島田信子
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Elucidation of the mechanism for the development of chronic obstructive pulmonary disease (COPD) by using vitamin C deficient micePrincipal Investigator
- Principal Investigator
  
  SHIMADA Nobuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
The target site and role of NDP kinase in cellular signaling networksPrincipal Investigator
- Principal Investigator
  
  SHIMADA Nobuko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼ/nm23に関する国際会議開催に向けての企画調査研究
- Principal Investigator
  
  木村成道
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Studies on the mechanism of NDP kinase/nm23 and its interacting proteins
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
ヌクレオシド二リン酸キナーゼの遺伝子発現調節の解析
- Principal Investigator
  
  石川直
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼの遺伝子発現調節と腫瘍細胞の転移能の変異との相関について
- Principal Investigator
  
  石川直
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Role of NDP kinase in cell growth and differentiation
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナ-ゼの構造と機能および遺伝子に関する研究
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼの機能解析と遺伝子の単離
- Principal Investigator
  
  木村成道
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Membrane-associated nucleoside diphosphate kinase: purification and its role in hormone sensitive adenylate cyclase system
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology

All 2009 2008 2007

All Journal Article Presentation

[Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease.2009
- Author(s)
  Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N. and Ishigami, A.
- Journal Title
  
  Biomed. Res.
  
  Pages: 0-0
- NAID
  130004903756
- Data Source
  KAKENHI-PROJECT-19590925
[Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008
- Author(s)
  Kondo, Y., Sasaki, T., Sato, Y., Amano, A., Iwama, M., Handa, S., Shimada, N., Fukuda, M., Akita, M., Lee, J., Jeong, KS., Maruyama, N. and Ishigami, A.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377
  
  Pages: 291-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるビタミンCの活性酸素消去能の検討2008
- Author(s)
  近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるビタミンCの活性酸素消去能の解析2008
- Author(s)
  近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] マウス肝臓におけるSMP30/GNLの組織学的加齢変化2008
- Author(s)
  半田節子、島田信子、天野晶子、福田貢、近藤嘉高、丸山直記、石神昭人
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 弱酸性域に至適pHを持つベータガラクトシダーゼ活性を用いた老化度測定法の開発2008
- Author(s)
  五味恵子、島田信子、福田貢、榊原達哉、半田節子、高橋良哉、丸山直記、石神昭人
- Organizer
  第48回日本臨床化学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] アルツハイマー病早期臨床検査試薬としてのシトルリン化GFAPサンドイッチELISA法の確立2008
- Author(s)
  石神昭人、半田節子、島田信子、丸山直記、真鍋幸子、高橋良哉、内田好昭
- Organizer
  第48回日本臨床化学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] ビタミン C 欠乏による SVCT1 および SVCT2 発現調節の検討2008
- Author(s)
  天野晶子、島田信子、岩間水輝、福田貢、半田節子、丸山直記、相垣敏郎、石神昭人
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] カルニチン合成系へのビタミンCの関与2008
- Author(s)
  石神昭人、古澤元、佐藤安訓、井内陽子、錦見盛光、村田晃、半田節子、島田信子、福田貢、高橋良哉
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] ビタミンC不足は老化を加速2007
- Author(s)
  石神昭人、佐藤安訓、近藤嘉高、古澤元、天野晶子、島田信子、福田貢、半田節子、久保幸穂、丸山直記
- Organizer
  第127回日本薬学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるペプチジルアルギニンデイミナーゼ2(PAD2)の加齢変化2007
- Author(s)
  島田信子、朝倉(遊長)由希、半田節子、町田武生、石神昭人
- Organizer
  第30回日本基礎老化学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 細胞老化関連遺伝子TARSH/Abi3bpの発現量低下と発癌の機能的関連2007
- Author(s)
  上川奈都子、島田信子、石神昭人、杉本昌隆、丸山直記、丸山光生
- Organizer
  第30回日本基礎老化学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590925

1. KIMURA Narimichi (60073029)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. ISHIKAWA Naoshi (30184485)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. FUKUDA Mitsugu (30100126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. MATSUZAKI Takao

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAGUSHI Takahiko (80073005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NOMURA Kohji (30073026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 石井章雄 (60167244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 戸田年総 (80133635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石神昭人 (50270658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. 渡辺和忠 (70114717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石嶋康史

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMADA Nobuko 島田 信子

AHIMADA Nobuko 島田 信子

Research Projects

Research Products

Co-Researchers

ビタミンCの体内動態及びビタミンCと骨粗鬆症に関する包括的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism for the development of chronic obstructive pulmonary disease (COPD) by using vitamin C deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The target site and role of NDP kinase in cellular signaling networksPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008

Author(s)

Journal Title

Data Source

[Presentation] 脳におけるビタミンCの活性酸素消去能の検討2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 脳におけるビタミンCの活性酸素消去能の解析2008

Author(s)

Organizer

SHIMADA Nobuko 島田信子

AHIMADA Nobuko 島田信子