SHIMADA Nobuko 島田信子

… Alternative Names

Researcher Number	60158962
External Links
Affiliation (based on the past Project Information) *help	2009: 東京都高齢者研究財団, 助手 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 助手 2007 – 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 助手 2000 – 2001: (財)東京都老人総合研究所, 遺伝子情報部門, 助手 2000: 東京都老人総合研究所, 遺伝子情報部門, 助手 … More
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Eating habits, studies on eating habits / Biological pharmacy Except Principal Investigator Biological pharmacy / Experimental pathology / Pathological medical chemistry / Functional biochemistry / 物質生物化学 / General medical chemistry
Keywords	Principal Investigator PC12D / PACAP / 呼吸器 / 肺 / COPD / ビタミンC / 老化 / 肺気腫 / 喫煙 / 酸化ストレス … More Except Principal Investigator nm23 / アイソフォーム / NDPキナーゼ / 細胞増殖 / ヌクレオシドニリン酸(NDP)キナーゼ / 細胞分化 / がん転移抑制 / シグナル伝達 / NDP kinase / Cell growth / NDPキナ-ゼ / cDNA / アイソフォ-ム / 遺伝子単離 / 蛋白一次構造 / 遺伝子構造 / 遺伝子発現 / 臓器・細胞特異的発現 / がん転移 / ヌクレオシド二リン酸キナーゼ / 転写開始点多型性 / RACE法 / コアプロモーター / CATアッセイ / 免疫染色 / タンパク質一次構造 / 遺伝子 / 分化 / 培養細胞 / Nm23 / Defferentiation / 酵素活性 / PC12細胞 / 神経突起形成 / NGF / dbcAMP / Signal transduction / Differentiation / Metastasis suppressor / ヌクレオシドニリン酸キナーゼ / アデニル酸シクラーゼ / GTP結合タンパク質(Gs) / ホルモン / グアニンヌクレオチド / 細胞膜結合性酵素 / GDPGTP / 細胞膜 / Nucleoside diphosphate kinase / Adenylate cyclase / GTP-binding protein(Gs) / Hormone / Guanine nucleotide Less

ビタミンCの体内動態及びビタミンCと骨粗鬆症に関する包括的研究Principal Investigator
- Principal Investigator
  
  島田信子
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Elucidation of the mechanism for the development of chronic obstructive pulmonary disease (COPD) by using vitamin C deficient micePrincipal Investigator
- Principal Investigator
  
  SHIMADA Nobuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
The target site and role of NDP kinase in cellular signaling networksPrincipal Investigator
- Principal Investigator
  
  SHIMADA Nobuko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼ/nm23に関する国際会議開催に向けての企画調査研究
- Principal Investigator
  
  木村成道
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Studies on the mechanism of NDP kinase/nm23 and its interacting proteins
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
ヌクレオシド二リン酸キナーゼの遺伝子発現調節の解析
- Principal Investigator
  
  石川直
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼの遺伝子発現調節と腫瘍細胞の転移能の変異との相関について
- Principal Investigator
  
  石川直
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Role of NDP kinase in cell growth and differentiation
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナ-ゼの構造と機能および遺伝子に関する研究
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
NDPキナーゼの機能解析と遺伝子の単離
- Principal Investigator
  
  木村成道
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Membrane-associated nucleoside diphosphate kinase: purification and its role in hormone sensitive adenylate cyclase system
- Principal Investigator
  
  KIMURA Narimichi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology

All 2009 2008 2007

All Journal Article Presentation

[Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease.2009
- Author(s)
  Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N. and Ishigami, A.
- Journal Title
  
  Biomed. Res.
  
  Pages: 0-0
- NAID
  130004903756
- Data Source
  KAKENHI-PROJECT-19590925
[Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008
- Author(s)
  Kondo, Y., Sasaki, T., Sato, Y., Amano, A., Iwama, M., Handa, S., Shimada, N., Fukuda, M., Akita, M., Lee, J., Jeong, KS., Maruyama, N. and Ishigami, A.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377
  
  Pages: 291-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるビタミンCの活性酸素消去能の検討2008
- Author(s)
  近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるビタミンCの活性酸素消去能の解析2008
- Author(s)
  近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] マウス肝臓におけるSMP30/GNLの組織学的加齢変化2008
- Author(s)
  半田節子、島田信子、天野晶子、福田貢、近藤嘉高、丸山直記、石神昭人
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 弱酸性域に至適pHを持つベータガラクトシダーゼ活性を用いた老化度測定法の開発2008
- Author(s)
  五味恵子、島田信子、福田貢、榊原達哉、半田節子、高橋良哉、丸山直記、石神昭人
- Organizer
  第48回日本臨床化学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] アルツハイマー病早期臨床検査試薬としてのシトルリン化GFAPサンドイッチELISA法の確立2008
- Author(s)
  石神昭人、半田節子、島田信子、丸山直記、真鍋幸子、高橋良哉、内田好昭
- Organizer
  第48回日本臨床化学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] ビタミン C 欠乏による SVCT1 および SVCT2 発現調節の検討2008
- Author(s)
  天野晶子、島田信子、岩間水輝、福田貢、半田節子、丸山直記、相垣敏郎、石神昭人
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] カルニチン合成系へのビタミンCの関与2008
- Author(s)
  石神昭人、古澤元、佐藤安訓、井内陽子、錦見盛光、村田晃、半田節子、島田信子、福田貢、高橋良哉
- Organizer
  第60回日本ビタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] ビタミンC不足は老化を加速2007
- Author(s)
  石神昭人、佐藤安訓、近藤嘉高、古澤元、天野晶子、島田信子、福田貢、半田節子、久保幸穂、丸山直記
- Organizer
  第127回日本薬学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 脳におけるペプチジルアルギニンデイミナーゼ2(PAD2)の加齢変化2007
- Author(s)
  島田信子、朝倉(遊長)由希、半田節子、町田武生、石神昭人
- Organizer
  第30回日本基礎老化学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590925
[Presentation] 細胞老化関連遺伝子TARSH/Abi3bpの発現量低下と発癌の機能的関連2007
- Author(s)
  上川奈都子、島田信子、石神昭人、杉本昌隆、丸山直記、丸山光生
- Organizer
  第30回日本基礎老化学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590925

1. KIMURA Narimichi (60073029)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. ISHIKAWA Naoshi (30184485)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. FUKUDA Mitsugu (30100126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. MATSUZAKI Takao

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAGUSHI Takahiko (80073005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NOMURA Kohji (30073026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 石井章雄 (60167244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 戸田年総 (80133635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石神昭人 (50270658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. 渡辺和忠 (70114717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石嶋康史

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMADA Nobuko 島田 信子

AHIMADA Nobuko 島田 信子

Research Projects

Research Products

Co-Researchers

ビタミンCの体内動態及びビタミンCと骨粗鬆症に関する包括的研究Principal Investigator

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Elucidation of the mechanism for the development of chronic obstructive pulmonary disease (COPD) by using vitamin C deficient micePrincipal Investigator

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The target site and role of NDP kinase in cellular signaling networksPrincipal Investigator

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[Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008

Author(s)

Journal Title

Data Source

[Presentation] 脳におけるビタミンCの活性酸素消去能の検討2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 脳におけるビタミンCの活性酸素消去能の解析2008

Author(s)

Organizer

SHIMADA Nobuko 島田信子

AHIMADA Nobuko 島田信子