NAGAOKA Isao 長岡功

Researcher Number	60164399
Other IDs
External Links
Affiliation (Current)	2021: 順天堂大学, 保健医療学部, 特任教授 2021: 順天堂大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2013 – 2020: 順天堂大学, 医学(系)研究科(研究院), 教授 2001 – 2015: 順天堂大学, 医学部, 教授 1992 – 1993: 順天堂大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including mycology) / General surgery / 細菌学 / Basic Section 49050:Bacteriology-related Except Principal Investigator Eating habits / Bacteriology (including mycology) / Basic Section 38050:Food sciences-related / Basic Section 49050:Bacteriology-related / Food science … More
Keywords	Principal Investigator 敗血症 / 抗菌ペプチド / 好中球 / alarmin / エンドトキシン / マクロファージ / サイトカイン / アポトーシス / Cathelicidin / エンドトキシンショック … More Except Principal Investigator グルコサミン / 機能性食品 / 敗血症 / 軟骨細胞 / サーチュイン / 抗炎症 / 炎症性サイトカイン / 炎症 / LL-37 / オートファジー / 滑膜細胞 / O-GlcNAc修飾 / 転写因子 / サブスタンスＰ / 抗炎症作用 / サイトカイン / サブスタンスＰ受容体 / サブスタンスP受容体 / 翻訳後修飾 / サブスタンスP / LPS / 抗菌ペプチド / 骨芽細胞 / 標的遺伝子 / 軟骨代謝 / 骨代謝 / グリコサミノグリカン / 糖化修飾 / Sp1 / IL-8 / 変形性関節症 / 糖鎖修飾 / 遺伝子発現 / ケタミン / MAPK / 悪性腫瘍 / 麻酔薬 / ペントバルビタール / プロポフォール / Lipopolysaccharide / sirtuin / LPS (lipopolysaccharide) / lipopolysaccharide / Sirtuin（サーチュイン） / NF-κB / p65 / 慢性掻痒 / シグナル伝達 / 鎮痛補助薬 / ガバペンチノイド / 掻痒 / ガバペンチン / プレガバリン / NK1受容体 / MAPキナーゼ / リポ多糖（LPS) / 翻訳語修飾 / PTM / アセチル化 / リポ多糖（LPS） / acetylation / 自然免疫 / acetyl化 / O-GlcNAc化 / エンドトキシン / 類洞内皮細胞 / 内毒素 / 血液浄化 / 血管内皮細胞 / 肝臓 / アセチルグルコサミン / 慢性疼痛 / 認知機能障害 / サブスンタンスP / 認知症の行動・心理症状 / 脳内炎症 / U373MG細胞 / シグナル伝達系 / マイクログリア / 認知症 / 漢方 / 行動・心理症状 / 動脈硬化症 / 細胞死 / 抗菌性ペプチド / 好中球 / ectosome / 抗菌活性分子 / lactoferrin / CRAMP / FPR2 / CXCR2 / エクトソーム / 抗菌活性 Less

食品素材グルコサミンの脱アセチル化酵素サーチュインを介した新規軟骨保護作用の解明Ongoing
- Principal Investigator
  
  五十嵐庸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Josai University
Host defense peptide LL-37 modulates the pathogenesis of sepsis by inducing the release of exosomesPrincipal InvestigatorOngoing
- Principal Investigator
  
  長岡功
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Juntendo University
感染刺激によって放出される抗菌性ペプチドLL-37による動脈硬化の増悪機構Ongoing
- Principal Investigator
  
  鈴木香
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Juntendo University
好中球細胞外小胞エクトソームの敗血症治療への応用を目指してOngoing
- Principal Investigator
  
  熊谷由美
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Juntendo University
機能性食品素材であるアセチルグルコサミンの抗炎症作用に関する分子メカニズムOngoing
- Principal Investigator
  
  染谷明正
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
認知症のリスクファクターとしての慢性疼痛におけるサブスタンスＰの役割Ongoing
- Principal Investigator
  
  山口敬介
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Juntendo University
機能性食品であるグルコサミンのオートファジーに対する新規作用の解明Ongoing
- Principal Investigator
  
  五十嵐庸
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Juntendo University
好中球エクトソームと危険信号分子アラーミンに着目した敗血症の新たな病態制御Principal InvestigatorOngoing
- Principal Investigator
  
  長岡功
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Juntendo University
Analysis of translational modifications of proteins involved in inflammatory signaling in sepsis
- Principal Investigator
  
  Murakami Taisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Juntendo University
Evaluation of the antimicrobial peptide LL-37 as an agent of LPS clearance
- Principal Investigator
  
  Suzuki Kaori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Juntendo University
molecular mechamisms of glucosamine for anti-inflammatory action
- Principal Investigator
  
  SOMEYA AKIMASA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Juntendo University
Elucidation of antipruritic mechanism of analgesic adjuvant via substance P receptorr
- Principal Investigator
  
  YAMAGUCHI KEISUKE
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Juntendo University
Roles of NETs and alarmins in the pathogenesis of sepsisPrincipal Investigator
- Principal Investigator
  
  NAGAOKA ISAO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Juntendo University
Evaluation of sirtuin roles in septic shock
- Principal Investigator
  
  MURAKAMI Taisuke
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Juntendo University
The elucidation of the new high dimension function of glucosamine.
- Principal Investigator
  
  IGARASHI Mamoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Juntendo University
Modulation of a novel death, pyroptosis by alarmins in septic shockPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Isao
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Juntendo University
Study of the molecular mechanisms of GlcN for antiinflammatory action in synovial cells.
- Principal Investigator
  
  SOMEYA AKIMASA
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
The Inhibitory Effects of Intravenous Anesthetics on Substance P Receptor in U373 MG Human Astrocytoma Cells.
- Principal Investigator
  
  YAMAGUCHI Keisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Juntendo University
Modulation of host cell apoptosis during sepsis by alarminsPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Juntendo University
Molecular mechanism for the regulation of septic shock by endogenous antimicrobial cathelicidin peptidesPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Isao
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Juntendo University
Modulation of neutrophil apoptosis in septic shock and its regulation by endogenous antimicrobial peptidesPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Isao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  JUNTENDO UNIVERSITY
LPS中和能を有する抗菌ペプチドによる敗血症治療の新たな試みPrincipal Investigator
- Principal Investigator
  
  長岡功
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Juntendo University
Evaluation of the expression of the neutrophil antibacterial defensin genesPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Isao
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Juntendo University School of Medicine

[Book] Functional Food Research 15 -健康寿命の延伸におけるファンクショナルフードの意義2019
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Total Pages
  115
- Publisher
  インフォノーツパブリッシング
- Data Source
  KAKENHI-PROJECT-17K00880
[Book] 分子栄養学 -科学的根拠に基づく食理学2019
- Author(s)
  長岡　功
- Total Pages
  241
- Publisher
  東京化学同人
- ISBN
  9784807916733
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] エンドトキシン・自然免疫研究22 -エンドトキシン・自然免疫研究の新たな可能性を求めて2019
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, Reich Johannes, 田村弘志, 長岡　功
- Total Pages
  82
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] エンドトキシン・自然免疫研究22 -エンドトキシン・自然免疫研究の新たな可能性を求めて2019
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, Reich Johannes, 田村弘志, 長岡　功
- Total Pages
  82
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-19K07562
[Book] エンドトキシン・自然免疫研究 222019
- Author(s)
  Kracklauer M, Tamura H, Nagaoka I, Reich J
- Total Pages
  82
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] エンドトキシン・自然免疫研究 222019
- Author(s)
  熊谷　由美, 村上　泰介, 桒原　京子, Reich Johannes, 田村　弘志, 長岡　功
- Total Pages
  82
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] エンドトキシン・自然免疫研究22 -エンドトキシン・自然免疫研究の新たな可能性を求めて2019
- Author(s)
  Kracklauer M, Tamura H, Nagaoka I, Reich J
- Total Pages
  82
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] エンドトキシン・自然免疫研究21- エンドトキシン・自然免疫研究のフロンティアをめざして2018
- Author(s)
  長岡　功, 細田浩司, 中村果歩, 胡　忠双, 村上泰介, 鈴木　香, 田村弘志
- Total Pages
  69
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] エンドトキシン・自然免疫研究21- エンドトキシン・自然免疫研究のフロンティアをめざして（小谷穣治, 長岡　功編集）2018
- Author(s)
  長岡　功, 細田浩司, 中村果歩, 胡　忠双, 村上泰介, 鈴木　香, 田村弘志　他
- Total Pages
  69
- Publisher
  医学図書出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] 血流改善成分の開発と応用2018
- Author(s)
  長岡功
- Total Pages
  231
- Publisher
  シーエムシー出版
- ISBN
  9784781313412
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] Functional Food Research 14 -ファンクショナルフードの未来2018
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Total Pages
  115
- Publisher
  インフォノーツパブリッシング
- Data Source
  KAKENHI-PROJECT-17K00880
[Book] 抗菌ペプチドの機能解明と技術利用2017
- Author(s)
  鈴木香, 長岡功
- Total Pages
  239
- Publisher
  CMC出版
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] 抗菌ペプチドの機能解明と技術利用（長岡　功監修）「Cathelicidin抗菌ペプチドの作用メカニズムと敗血症治療への応用」2017
- Author(s)
  鈴木香, 長岡功, 川村出, 岩室祥一, 若林裕之, 橋本茂樹, 田口精一, 山﨑浩司, 吉村幸則, 相沢智康, 谷口正之, 落合秋人, 加治屋勝子, 南雄二, 中神啓徳, 田村弘志, Johannes Reich, 伊藤英晃, ニヨンサバフランソワ, 善藤威史　他
- Total Pages
  239
- Publisher
  シーエムシー出版
- ISBN
  9784781312453
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] 抗菌ペプチドの機能解明と技術利用2017
- Author(s)
  長岡　功
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] 抗菌ペプチドの機能解明と技術利用2017
- Author(s)
  鈴木　香, 長岡　功
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] 抗菌ペプチドの機能解明と技術利用2017
- Author(s)
  田村弘志, Johannes Reich, 長岡　功
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] 抗菌ペプチドの機能解明と技術利用2017
- Author(s)
  長岡　功
- Total Pages
  239
- Publisher
  シーエムシー出版
- ISBN
  9784781312453
- Data Source
  KAKENHI-PROJECT-17K08840
[Book] エンドトキシン・自然免疫研究20（隅田泰生、長岡功編集）「平成 28 年度日本エンドトキシン・自然免疫研究会奨励賞・最優秀賞受賞講演：ヒト生体防御ペプチドLL-37の血管内皮細胞に対する作用～エンドトキシンとの相互作用について～」2017
- Author(s)
  深瀬浩一, 下山敦史, 藤本ゆかり, 鈴木香, 長岡功, 土谷正和, 清水智治, 小幡徹, 園田寛道, 三宅亨, 遠藤善裕, 谷徹, 谷眞至, 高橋徹, 萩沢康介, 木下学, 宮脇博基, 佐藤俊一, 鈴木英紀, 武岡真司　他
- Total Pages
  67
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] Functional Food Research 122016
- Author(s)
  橋口素子, 鈴木香, 金子和夫, 長岡　功
- Total Pages
  98
- Publisher
  エイド出版
- Data Source
  KAKENHI-PROJECT-16K08789
[Book] エンドトキシン・自然免疫研究18 自然免疫における生体防御ペプチドの多様性.2015
- Author(s)
  鈴木　香, 長岡　功
- Total Pages
  100
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] エンドトキシン・自然免疫研究18 自然免疫における生体防御ペプチドの多様性.2015
- Author(s)
  胡　忠双, 村上泰介, 鈴木　香, 田村弘志, 長岡　功
- Total Pages
  100
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] エンドトキシン・自然免疫研究18 自然免疫における生体防御ペプチドの多様性.2015
- Author(s)
  多田浩之, 松下健二, 松山考司, 長岡　功, 高田春比古
- Total Pages
  100
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] グルコサミン研究１０2014
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Publisher
  エイド出版
- Data Source
  KAKENHI-PROJECT-23580183
[Book] エンドトキシン・自然免疫研究17 －エンドトキシン・自然免疫の展開：新しい機序、診断、応用.2014
- Author(s)
  胡　忠双, 村上泰介, 鈴木　香, 田村弘志, 長岡　功
- Total Pages
  105
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-26460538
[Book] グルコサミンとN−アセチルグルコサミンは軟骨細胞においてサーチュイン1の遺伝子発現を亢進する.グルコサミン研究102014
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Publisher
  エイド出版(出版決定)
- Data Source
  KAKENHI-PROJECT-23580183
[Book] グルコサミン研究９2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Total Pages
  104
- Publisher
  エイド出版
- Data Source
  KAKENHI-PROJECT-23580183
[Book] グルコサミンの関節に及ぼす効果と機能性食品開発.アンチ・エイジングシリーズ3骨研究最前線〜代謝・疾患のメカニズムから再生医療・創薬・リハビリ機器・機能性食品開発まで〜2013
- Author(s)
  長岡功、五十嵐庸
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-23580183
[Book] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である.グルコサミン研究9−より多くの人達の関心を得るために.菅原忍、岡本芳晴、奥村正裕、中村洋、野村義宏、和田正裕、長岡功編集2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Publisher
  エイド出版
- Data Source
  KAKENHI-PROJECT-23580183
[Book] Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. Proceedings of the 9th Asia Pacific Chitin and Chitosan Symposium (Nha Trang, Vietnam, Aug 3-6, 2011), Edited by Ngo ND, Vårum KM, Nguyen DA, Trang TS.2012
- Author(s)
  Igarashi M, Sakamoto K, Nagaoka I.
- Publisher
  Agricultural Publishing House
- Data Source
  KAKENHI-PROJECT-23580183
[Book] Biological activities of glucosamine and its related substances. Advance in Food and Nutrition Research Vol. 65, Marine Medical Foods : Implications and Applications–Animals and Microbes. Edited by Kim, S-K.2012
- Author(s)
  Nagaoka I, Igarashi M, Sakamoto K.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-23580183
[Book] Advances in Food and Nutrition Research, Volume 65 (edited by Se-Kwon Kim)2012
- Author(s)
  Nagaoka I, Igarashi M and Sakamoto K
- Total Pages
  523
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-23580183
[Book] エンドトキシン研究14自然免疫と生体防御, エンドトキシンで誘発される血管内皮細胞のアポトーシスに対する抗菌ペプチドLL-37の保護効果2011
- Author(s)
  鈴木香,村上泰介,田村弘志,長岡功, (福井博,谷徹,嶋田紘編集)
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-23590519
[Book] 炎症と免疫応答現代栄養学を理解するための分子生物学入門(加藤茂明編著)2010
- Author(s)
  長岡功
- Total Pages
  221
- Publisher
  光生館,東京
- Data Source
  KAKENHI-PROJECT-20590456
[Book] エンドトキシン研究11新生「日本エンドトキシン・自然免疫研究会」の発展を願って(嶋田紘,谷徹,横地高志,清水智治編集)(Cathelicidinファミリーの生体防御ペプチドCAP11を用いた敗血症性メディエーターの制御)2009
- Author(s)
  村上泰介,田村弘志,長岡功
- Total Pages
  44
- Publisher
  医学図書出版,東京
- Data Source
  KAKENHI-PROJECT-20590456
[Book] グルコサミン研究42009
- Author(s)
  長岡功
- Total Pages
  106
- Publisher
  エイト出版
- Data Source
  KAKENHI-PROJECT-20590456
[Book] エンドトキシン研究12自然免疫学の新たな展開(高田春比古,谷徹,嶋田紘編集)(単核食細胞からのHMGB1放出に及ぼす生体防御ペプチドCAP11の効果)2009
- Author(s)
  渋沢謙太郎,村上泰介,田村弘志,長岡功
- Total Pages
  118
- Publisher
  医学図書出版,東京
- Data Source
  KAKENHI-PROJECT-20590456
[Book] Mediators of Inflammation2007
- Author(s)
  Nagaoka Isao
- Publisher
  Bactericidal and LPS-neutralizing activities of a human antimicrobial cathelicidin nentide CAP 18/LL-37
- Data Source
  KAKENHI-PROJECT-17590401
[Book] エンドトキシン研究9-自然免疫の最前線-2006
- Author(s)
  長岡功
- Total Pages
  172
- Publisher
  医学図書出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Book] Cathelicidinファミリーの殺菌ペプチドhCAP18/LL-37の好中球アポトーシスに及ぼす影響.2006
- Author(s)
  長岡功
- Publisher
  医学図書出版(forthcoming)
- Data Source
  KAKENHI-PROJECT-17590401
[Book] 別冊・医学のあゆみ2004
- Author(s)
  長岡功, 諌山太郎
- Data Source
  KAKENHI-PROJECT-15590400
[Book] 別冊・医学のあゆみ2004
- Author(s)
  長岡功, 諌山太郎
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Yokukansan, a Japanese Herbal Medicine, suppresses Substance P-induced Production of Interleukin-6 and Interleukin-8 by Human U373 MG Glioblastoma Astrocytoma Cells.2020
- Author(s)
  Yamaguchi K, Yamazaki S, Kumakura S, Someya A, Iseki M, Inada E, Nagaoka I
- Journal Title
  
  Endocr Metab Immune Disord Drug Targets.
  
  Volume: -
- DOI
  10.2174/1871530320666200131103733
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-18K08866
[Journal Article] グルコサミンによるO-N-アセチルグルコサミン修飾を介したNF-κBの制御2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00844
[Journal Article] Impact of primary tumor location as a predictive factor in patients suffering from colorectal cancer treated with cytotoxic anticancer agents based on the collagen gel droplet-embedded drug sensitivity test.2019
- Author(s)
  Ochiai T, Nishimura K, Watanabe T, Kitajima M, Nakatani A, Nagayasu K, Sakuyama N, Sato T, Kishine K, Abe Y, Nagaoka I
- Journal Title
  
  Oncology Letters
  
  Volume: 17 Pages: 1842-1850
- DOI
  10.3892/ol.2018.9805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-17K10653
[Journal Article] Bacterial lipopolysaccharide and antimicrobial LL-37 enhance ICAM-1 expression and NF-κB p65 phosphorylation in senescent endothelial cells2019
- Author(s)
  Suzuki K, Ohkuma M, Nagaoka I
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 44 Pages: 1187-1196
- DOI
  10.3892/ijmm.2019.4294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-19K07545, KAKENHI-PROJECT-16K08789
[Journal Article] Evaluation of the 5-fluorouracil Plasma Level in Patients With Colorectal Cancer Undergoing Continuous Infusion Chemotherapy2019
- Author(s)
  Abe Y, Sakuyama N, Sato T, Kishine K, Nagayasu K, Nakatani A, Kitajima M, Watanabe T, Nishimura K, Ochiai T, Nagaoka I
- Journal Title
  
  Mol Clin Oncol ,
  
  Volume: 11 Pages: 289-295
- DOI
  10.3892/mco.2019.1893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] Cartilage Metabolism in Endurance Athletes and Chondroprotective Action of Glucosamine2019
- Author(s)
  Nagaoka I
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 65 Issue: 2 Pages: 184-193
- DOI
  10.14789/jmj.2019.65.jmj19-ln01
  10.14789/jmj.2019.65.JMJ19-LN01
- NAID
  130007670504
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] The Potential Use of Grape Phytochemicals for Preventing the Development of Intestine-Related and Subsequent Inflammatory Diseases2019
- Author(s)
  Santa K, Kumazawa Y, Nagaoka I
- Journal Title
  
  Endocr Metab Immune Disord Drug Targets
  
  Volume: 19 Pages: 794-802
- DOI
  10.2174/1871530319666190529105226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] Effect of Aging on the Tendon Structure and Tendon-Associated Gene Expression in Mouse Foot Flexor Tendon2019
- Author(s)
  Sugiyama Y, Naito K, Goto K, Kojima Y, Furuhata A, Igarashi M, Nagaoka I, Kaneko K
- Journal Title
  
  Biomed Rep
  
  Volume: 10 Pages: 238-244
- DOI
  10.3892/br.2019.1200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] Chondroprotective Action of Glucosamine, a Chitosan Monomer, on the Joint Health of Athletes2019
- Author(s)
  Nagaoka I, Tsuruta A, Yoshimura M
- Journal Title
  
  Int J Biol Macromol
  
  Volume: 132 Pages: 795-800
- DOI
  10.1016/j.ijbiomac.2019.03.234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] Low Endotoxin Recovery-Masking of Naturally Occurring Endotoxin.2019
- Author(s)
  Reich J, Weyer FA, Tamura H, Nagaoka I, Motschmann H
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Pages: 838-838
- DOI
  10.3390/ijms20040838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] 滑膜細胞におけるグルコサミンの転写因子NF-κBの制御機構2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  Functional food research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00844
[Journal Article] Investigation of the kinetics and mechanism of low endotoxin recovery in a matrix for biopharmaceutical drug products.2018
- Author(s)
  Reich J, Tamura H, Nagaoka I.
- Journal Title
  
  Biologicals
  
  Volume: 53 Pages: 1-9
- DOI
  10.1016/j.biologicals.2018.04.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840
[Journal Article] Evaluation of the effect of the administration of a glucosamine-containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double-blind placebo-controlled study.2018
- Author(s)
  Tsuruta A, Horiike T, Yoshimura M, Nagaoka I
- Journal Title
  
  Mol Med Rep
  
  Volume: 18 Pages: 3941-3948
- DOI
  10.3892/mmr.2018.9396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] MrgX2?mediated internalization of LL?37 and degranulation of human LAD2 mast cells2018
- Author(s)
  Murakami T, Suzuki K, Niyonsaba F, Tada H, Reich J, Tamura H, Nagaoka I.
- Journal Title
  
  Mol Med Rep
  
  Volume: 18 Pages: 4951-4959
- DOI
  10.3892/mmr.2018.9532
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-17K10254
[Journal Article] Protective effect of a newly developed fucose-deficient recombinant antithrombin against histone-induced endothelial damage2018
- Author(s)
  Iba T, Hirota T, Sato K, Nagaoka I
- Journal Title
  
  Int J Hematol
  
  Volume: 107 Pages: 528-534
- DOI
  10.1007/s12185-018-2402-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840
[Journal Article] Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis.2018
- Author(s)
  Iba T, Levy JH, Hirota T, Hiki M, Sato K, Murakami T, Nagaoka I.
- Journal Title
  
  Thromb Res
  
  Volume: 171 Pages: 1-6
- DOI
  10.1016/j.thromres.2018.09.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840
[Journal Article] JAK2/STAT3 pathway as a therapeutic target in ovarian cancers.2018
- Author(s)
  Yoshikawa T, Miyamoto M, Aoyama T, Soyama H, Goto T, Hirata J, Suzuki A, Nagaoka I, Tsuda H, Furuya K, Takano M
- Journal Title
  
  Oncol Lett
  
  Volume: 15 Pages: 5772-5780
- DOI
  10.3892/ol.2018.8028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08840
[Journal Article] 肝類洞内皮細胞の血液浄化作用に対するヒト生体防御ペプチドLL-37の効果－エンドトキシン除去作用に着目して－.2018
- Author(s)
  鈴木　香, 村上泰介, 胡　忠双, 長岡　功
- Journal Title
  
  日本血管血流学会誌
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-16K08789
[Journal Article] Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide2017
- Author(s)
  Hu Z, Murakami T, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Tabe Y, Nagaoka I.
- Journal Title
  
  Int J Mol Med
  
  Volume: in press Pages: 549-558
- DOI
  10.3892/ijmm.2017.2870
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-26460538
[Journal Article] Ketamine suppresses the substance P-induced production of IL-6 and IL-8 by human U373MG glioblastoma/astrocytoma cells.2017
- Author(s)
  Keisuke Yamaguchi, Isao Nagaoka
- Journal Title
  
  Int J Mol Med.
  
  Volume: 39 Pages: 687-692
- DOI
  10.3892/ijmm.2017.2875
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10564
[Journal Article] Evaluation of the effect of aloe-emodin on the proliferation and apoptosis of human synovial MH7A cells; a comparison with methotrexate.2017
- Author(s)
  Hashiguchi M, Suzuki K, Kaneko K, Nagaoka I
- Journal Title
  
  Mol. Med. Reports
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08789
[Journal Article] Evaluation of the effect of aloe-emodin on the proliferation and apoptosis of human synovial MH7A cells; a comparison with methotrexate.2017
- Author(s)
  Hashiguchi M, Suzuki K, Kaneko K, Nagaoka I
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 15 Pages: 4398-4404
- DOI
  10.3892/mmr.2017.6541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08789
[Journal Article] The Comparison of the Protective Effects of α- and β-Antithrombin against Vascular Endothelial Cell Damage Induced by Histone in Vitro2017
- Author(s)
  Iba T, Sasaki T, Ohshima K, Sato K, Nagaoka I, Thachil J
- Journal Title
  
  TH Open
  
  Volume: 1
- DOI
  10.1055/s-0037-1603926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840
[Journal Article] Evaluation of the effect of recombinant thrombomodulin on a lipopolysaccharide-induced murine sepsis model2017
- Author(s)
  Takehara K, Murakami T, Kuwahara-Arai K, Iba T, Nagaoka I, Sakamoto K
- Journal Title
  
  Exp Ther Med
  
  Volume: 13 Pages: 2969-2974
- DOI
  10.3892/etm.2017.4308
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-26460538
[Journal Article] Bacterial Endotoxin Assays Relevant to Host Defense Peptides2016
- Author(s)
  Tamura H, Reich J, Nagaoka I
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 62 Issue: 2 Pages: 132-140
- DOI
  10.14789/jmj.62.132
- NAID
  130005162209
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Vitamin D_3 analog maxacalcitol (OCT) induces hCAP-18/LL-37 production in human oral epithelial cells.2016
- Author(s)
  Hiroyuki Tada, Takamitsu Shimizu, Isao Nagaoka, Haruhiko Takada
- Journal Title
  
  Biomedical Research
  
  Volume: 37 Issue: 3 Pages: 199-205
- DOI
  10.2220/biomedres.37.199
- NAID
  130005161054
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463225, KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-16H00685, KAKENHI-PROJECT-26460538
[Journal Article] Physiological levels of pentraxin 3 and albumin attenuate vascular endothelial cell damage induced by histone H3 in vitro2016
- Author(s)
  Iba T, Hamakubo T, Nagaoka I, Sato K, Thachil J
- Journal Title
  
  Microcirculation.
  
  Volume: 23 Pages: 240-247
- DOI
  10.1111/micc.12269
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25462831, KAKENHI-PROJECT-16K11421
[Journal Article] The Effects of the Human Host Defense Peptide LL-37 on Endothelial Cells2016
- Author(s)
  Suzuki K, Nagaoka I
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 62 Issue: 2 Pages: 105-111
- DOI
  10.14789/jmj.62.105
- NAID
  130005162205
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-26460538
[Journal Article] Release mechanism of high mobility group nucleosome binding protein 1 from lipopolysaccharide-stimulated macrophages.2016
- Author(s)
  Murakami T, Hu Z, Tamura H, Nagaoka I
- Journal Title
  
  Molecular medicine reports
  
  Volume: 13 Pages: 3115-3120
- DOI
  10.3892/mmr.2016.4893
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-24590535
[Journal Article] ピロトーシスによる炎症惹起と抗菌ペプチドによる制御2016
- Author(s)
  胡　忠双, 長岡　功
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 6 Pages: 210-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Human host defense cathelicidin peptide LL-37 enhances the lipopolysaccharide uptake by liver sinusoidal endothelial cells without cell activation.2016
- Author(s)
  Suzuki K, Murakami T, Hu Z, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I
- Journal Title
  
  J Immunol
  
  Volume: 196 Pages: 1338-1347
- DOI
  10.4049/jimmunol.1403203
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-16K08789
[Journal Article] Modulation of Macrophage Cell Death, Pyroptosis by Host Defense Peptide LL-372016
- Author(s)
  Hu Z, Nagaoka I
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 62 Issue: 2 Pages: 98-104
- DOI
  10.14789/jmj.62.98
- NAID
  130005162200
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice.2016
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Nagaoka I
- Journal Title
  
  Int Immunol
  
  Volume: 28 Pages: 245-253
- DOI
  10.1093/intimm/dxv113
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-16K08789
[Journal Article] Have Host Defense Peptides Been Acting in Innate Immunity Since the Trilobites of the Cambrian Period 540 Million Years Ago?2016
- Author(s)
  Nagaoka I
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 62 Issue: 2 Pages: 96-97
- DOI
  10.14789/jmj.62.96
- NAID
  130005162201
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction.2015
- Author(s)
  Iba T, Hashiguchi N, Nagaoka I, Tabe Y, Kadota K, Sato K
- Journal Title
  
  Intensive Care Medicine Experimental
  
  Volume: 3 Pages: 36-36
- DOI
  10.1186/s40635-015-0072-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-25462831
[Journal Article] Neutrophil extracellular traps, damage-associated molecular patterns, and cell death during sepsis.2014
- Author(s)
  Iba T, Murai M, Nagaoka I, Tabe Y.
- Journal Title
  
  Acute Med Surg
  
  Volume: 1 Pages: 2-9
- DOI
  10.1002/ams2.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] Effect of Hemoperfusion Using Polymyxin B-immobilized Fibers on Acute Lung Injury in a Rat Sepsis Model.2014
- Author(s)
  Iba T, Nagaoka I, Yamada A, Nagayama M, Miki T.
- Journal Title
  
  Int J Med Sci
  
  Volume: 11 Pages: 255-261
- DOI
  10.7150/ijms.6276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519, KAKENHI-PROJECT-25462831, KAKENHI-PROJECT-26460538
[Journal Article] 抗菌ペプチドによる敗血症ショックの制御2014
- Author(s)
  長岡功,胡忠双,鈴木香,田村弘志
- Journal Title
  
  化学療法の領域
  
  Volume: 30 Pages: 615-623
- URL
  https://www.iyaku-j.com/iyakuj/system/dc8/index.php?trgid=28241
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] Combination of antithrombin and recombinant thrombomodulin attenuates leukocyte-endothelial interaction and suppresses the increase of intrinsic DAMPs in endotoxemic rats.2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Yamada A, Nagaoka I
- Journal Title
  
  J Surg Res
  
  Volume: 187 Pages: 581-586
- DOI
  10.1016/j.jss.2013.10.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519, KAKENHI-PROJECT-25462831
[Journal Article] Combination of antithrombin and recombinant thrombomodulin attenuates leukocyte-endothelial interaction and suppresses the increase of intrinsic damage-associated molecular patterns in endotoxemic rats.2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Yamada A, Nagaoka I
- Journal Title
  
  J Surg Res
  
  Volume: 187 Pages: 581-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] 抗菌ペプチドによる敗血症ショックの制御2014
- Author(s)
  長岡　功, 胡　忠双, 鈴木　香, 田村弘志
- Journal Title
  
  化学療法の領域
  
  Volume: 30 Pages: 59-67
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] グルコサミンは転写因子Sp1のO-N-アセチルグルコサミン修飾を介してIL-8産生を抑制する2014
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 20 Pages: 89-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592232
[Journal Article] Combination of antithrombin and recombinant thrombomodulin modulates neutrophil cell-death and decreases circulating DAMPs levels in endotoxemic rats.2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Tabe Y, Nagaoka I
- Journal Title
  
  Thromb Res
  
  Volume: 134 Pages: 169-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I
- Journal Title
  
  PLOS ONE
  
  Volume: 9(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] Is the neutrophil a 'prima donna' in the procoagulant process during sepsis?2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Tabe Y, Nagaoka I.
- Journal Title
  
  Critical Care
  
  Volume: 8 Pages: 230-230
- DOI
  10.1186/cc13983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462831, KAKENHI-PROJECT-26460538
[Journal Article] Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism.2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I
- Journal Title
  
  PLOS ONE
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism.2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I.
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0085765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] グルコサミンによる滑膜炎症の分子制御メカニズム2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 19 Pages: 111-115
- NAID
  40019737659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592232
[Journal Article] The anticoagulant therapy for sepsis-associated disseminated intravascular coagulation.2013
- Author(s)
  Iba T, Nagaoka I, Boulat M.
- Journal Title
  
  Thromb Res
  
  Volume: 131 Pages: 383-389
- DOI
  10.1016/j.thromres.2013.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol2013
- Author(s)
  Kumakura S, Yamaguchi K, Sugasawa Y, Murakami T, Kikuchi T, Inada E, Nagaoka I.
- Journal Title
  
  Mol Med Rep
  
  Volume: 8 Pages: 1643-1648
- DOI
  10.3892/mmr.2013.1745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519, KAKENHI-PROJECT-24890234
[Journal Article] Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol2013
- Author(s)
  Kumakura S, Yamaguchi K, Nagaoka I et al
- Journal Title
  
  Mol Med Rep
  
  Volume: 8 Pages: 8-1643
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] グルコサミンによる転写因子Sp1のO-N-アセチルグルコサミン修飾2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  グルコサミン研究
  
  Volume: 9 Pages: 48-52
- Data Source
  KAKENHI-PROJECT-23592232
[Journal Article] Effects of nitrous oxide on the production of cytokines and chemokines by the2013
- Author(s)
  Kumakura S, Yamaguchi K, Sugasawa Y, Murakami T, Kikuchi T, Inada E, Nagaoka
- Journal Title
  
  Mol Med Rep.
  
  Volume: 3 Pages: 1643-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] 5. Effects of sevoflurane and propofol on pulmonary inflammatory responses during lung resection2012
- Author(s)
  Sugasawa Y, Yamaguchi K, Kumakura S, Murakami T, Suzuki K, Nagaoka I
- Journal Title
  
  J Anesth
  
  Volume: 26 Pages: 9-62
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] 滑膜細胞の遺伝子発現に対するグルコサミンの影響2012
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Journal Title
  
  グルコサミン研究
  
  Volume: 8 Pages: 24-32
- Data Source
  KAKENHI-PROJECT-23592232
[Journal Article] Modulation of neutrophil apoptosis by antimicrobial peptides2012
- Author(s)
  Nagaoka I, Suzuki K, Niyonsaba F, Tamura H, Hirata M
- Journal Title
  
  ISRN Microbiol.
  
  Volume: 27
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] Modulation of neutrophil apoptosis by antimicrobial peptides2012
- Author(s)
  Nagaoka I, Suzuki K, Niyonsaba F, Tamura H, Hirata M
- Journal Title
  
  ISRN Microbiol
  
  Volume: Volume 2012, Article ID 345791 Pages: 12-12
- DOI
  10.5402/2012/345791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519, KAKENHI-PROJECT-23591655
[Journal Article] Human antimicrobial cathelicidin peptide LL-372011
- Author(s)
  Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I
- Journal Title
  
  International Immunology
  
  Volume: 23 Pages: 185-193
- DOI
  10.1093/intimm/dxq471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590519
[Journal Article] Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation2011
- Author(s)
  Igarashi M, Sakamoto K, Nagaoka I.
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: Vol. 28, No. 3 Pages: 373-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580183
[Journal Article] The effect of one-lung ventilation upon pulmonary inflammatoryresponses during lung resection2011
- Author(s)
  Sugasawa Y, Yamaguchi K, , Nagaoka I et al
- Journal Title
  
  J Anesth
  
  Volume: 25 Pages: 7-170
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] Effects of sivelestat on bronchial inflammatory responses after esophagectomy2011
- Author(s)
  Yamaguchi K, Nagaoka I, et al
- Journal Title
  
  Int J Mol Med
  
  Volume: 28 Pages: 92-187
- Data Source
  KAKENHI-PROJECT-23592265
[Journal Article] Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation.2011
- Author(s)
  Igarashi M, Sakamoto K and Nagaoka I
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 28 Pages: 373-379
- DOI
  10.3892/ijmm.2011.686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580183
[Journal Article] Human antimicrobial cathelicidin peptide LL-37 suppresses the lipopolysaccharide-induced apoptosis of endothelial cell.2011
- Author(s)
  Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I
- Journal Title
  
  Int Imunol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Evaluation of the effect of α-defensins human neutrophil peptides on neutrophil apoptosis.2010
- Author(s)
  Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M
- Journal Title
  
  Int J Mol Med 26
  
  Pages: 925-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Evaluation of the effect of α-defensins human neutrophil peptides on neutrophil apoptosis.2010
- Author(s)
  Isao Nagaoka
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 26 Pages: 925-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] LPS刺激によるマクロファージ様細胞からのHMGB1放出と抗菌ペプチドCAP11の抑制効果2010
- Author(s)
  長岡功,渋沢謙太郎,鈴木香,五十嵐庸,田村弘志
- Journal Title
  
  日本血流血管学会誌 2
  
  Pages: 35-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Augmentation of the antimicrobial activities of guinea pig cathelicidin CAP11-derived peptides by amino acid substitutions.2009
- Author(s)
  Okuda D, Yomogida S, Kuwahara-Arai K, Hitamatsu K, Tamura H, Nagaoka I
- Journal Title
  
  Int J Mol Med 23
  
  Pages: 501-508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Antimicrobial cathelicidin peptide CAP11 suppresses HMGB1 release from lipopolysaccharide-stimulated mononuclear phagocytes via the prevention of necrotic cell death.2009
- Author(s)
  Shibusawa K, Murakami T, Yomogida S, Tamura H, Nagaoka I
- Journal Title
  
  Int J Mol Med 23
  
  Pages: 341-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] 好中球機能の基礎2008
- Author(s)
  長岡功
- Journal Title
  
  皮膚アレルギーフロンティア 6
  
  Pages: 13-20
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Evaluation of the effect of human β-defensins on neutrophil apoptosis2008
- Author(s)
  Nagaoka Isao
- Journal Title
  
  International Immunology 20
  
  Pages: 543-553
- NAID
  10021240643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] Evaluation of the effect of human β-defensins on neutrophil apoptosis.2008
- Author(s)
  Nagaoka I, Niyonsaba F, Tsutsumi-Ishii Y, Tamura H, Hirata M
- Journal Title
  
  Int Immunol 20
  
  Pages: 543-553
- NAID
  10021240643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590456
[Journal Article] Evaluation of the effect of human β-defensins on neutrophil apoptosis2008
- Author(s)
  Nagaoka, I, Niyonsaba, F, Tsutsumi-Ishii, Y, Tamura, H, Hirata, M
- Journal Title
  
  Int Immunol 20
  
  Pages: 543-553
- NAID
  10021240643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] Antibacterial cathelicidin peptide CAP 11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes2007
- Author(s)
  Murakami, T, Yomogida, S, Someya, A, Kuwahara-Arai, K, Tamura, H, Nagaoka, I
- Journal Title
  
  FEBS Lett 581
  
  Pages: 140-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X72006
- Author(s)
  Nagaoka, I, Tamura, H, Hirata, M
- Journal Title
  
  J Immnol 176
  
  Pages: 3044-3052
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] Determination of the antibacterial and LPS-neutralizing regions of guinea pig neutrophil cathelicidin peptide CAP 112006
- Author(s)
  Okuda, D, Yomogida, S, Tamura, H, Nagaoka, I
- Journal Title
  
  Antimicrob Agents Chernother 50
  
  Pages: 2602-2607
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] An antimicrobial cathelicidin peptide,human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X_72006
- Author(s)
  Nagaoka Isao
- Journal Title
  
  Journal of Immunology 176
  
  Pages: 3044-3052
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] An antimicrobial cathelicidin peptide, human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPPL1 and P2X_7.2006
- Author(s)
  Nagaoka Isao
- Journal Title
  
  Journal of Immunology 176
  
  Pages: 3044-3052
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] 内因性抗菌ペプチドを用いた感染症治療を目指して.2005
- Author(s)
  長岡功
- Journal Title
  
  化学療法の領域 21
  
  Pages: 1807-1814
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats.2005
- Author(s)
  Fukumoto K, Nagaoka I, Yamataka A, Kobayashi H, Yanai T, Kato Y, Miyano T
- Journal Title
  
  Pediatr Surg Int 21
  
  Pages: 20-24
- NAID
  10019041914
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] The effect of antibacterial peptide human beta-defensin-2 on interleukin-18 secretion by keratinocytes.2005
- Author(s)
  Sampanthanarak P, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura K, Ogawa H
- Journal Title
  
  J Dermatol Sci 37
  
  Pages: 188-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions.2005
- Author(s)
  Nagaoka Isao
- Journal Title
  
  Inflammation Research 57
  
  Pages: 66-73
- Data Source
  KAKENHI-PROJECT-17590401
[Journal Article] Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions.2005
- Author(s)
  Nagaoka I, Kuwahara-Arai K, Tamura H, Hiramatsu K, Hirata M
- Journal Title
  
  Inflamm Res 54
  
  Pages: 66-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] 好中球アポトーシスの分子制御2004
- Author(s)
  長岡功
- Journal Title
  
  臨床免疫 43
  
  Pages: 236-242
- NAID
  40006647018
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Antibacterial cathelicidin peptide CAP11 inhibits the lipopolysaccharide(LPS)-induced suppression of neutrophil apoptosis by blocking the binding of LPS to target cells.2004
- Author(s)
  Isao Nagaoka, et al.
- Journal Title
  
  Inflammation Research 53
  
  Pages: 609-622
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils.2004
- Author(s)
  Niyonsaba F, Ogawa H, Nagaoka I
- Journal Title
  
  Immunology 111
  
  Pages: 273-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Cathelicidinファミリーの殺菌ペプチドによる好中球アポトーシスの制御-LPS刺激による好中球アポトーシスの制御におよぼすCAP11の効果2004
- Author(s)
  長岡功, 他
- Journal Title
  
  エンドトキシン研究 7
  
  Pages: 55-64
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Cathelicidinファミリーの殺菌ペプチドCAP11による好中球アポトーシスの制御2004
- Author(s)
  長岡功, 他
- Journal Title
  
  炎症・再生 24
  
  Pages: 166-172
- NAID
  10026498445
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] 炎症・白血球・ラジカル2004
- Author(s)
  長岡功
- Journal Title
  
  日本病態生理学会誌 13
  
  Pages: 31-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Antibacterial cathelicidin peptide CAP11 inhibits the lipopolysaccharide (LPS)-induced suppression of neutrophil apoptosis by blocking the binding of LPS to target cells.2004
- Author(s)
  Isao Nagaoka, et al.
- Journal Title
  
  Inflammation Research 53
  
  Pages: 609-622
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] 好中球アポトーシスの分子制御2004
- Author(s)
  長岡功
- Journal Title
  
  臨床免疫 433
  
  Pages: 236-242
- NAID
  40006647018
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Antibacterial cathelicidin peptide CAP11 inhibits the lipopolysaccharide (LPS)-induced suppression of neutrophil apoptosis by blocking the binding of LPS to target cells.2004
- Author(s)
  Nagaoka I, Yomogida S, Tamura H, Hirata M
- Journal Title
  
  Inflamm Res 53
  
  Pages: 609-622
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats.2004
- Author(s)
  Koji Fukumoto, Isao Nagaoka et al.
- Journal Title
  
  Pediatric Surgery International 21
  
  Pages: 20-24
- NAID
  10019041914
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] Cathelicidinファミリーの殺菌ペプチドによる好中球アポトーシスの制御-LPS刺激による好中球アポトーシスの抑制におよぼすCAP11の効果2004
- Author(s)
  長岡功, 他
- Journal Title
  
  エンドトキシン研究 7
  
  Pages: 55-64
- Data Source
  KAKENHI-PROJECT-15590400
[Journal Article] 抗菌ペプチドによる敗血症ショックの制御.
- Author(s)
  長岡　功, 胡　忠双, 鈴木　香, 田村弘志
- Journal Title
  
  化学療法の領域
  
  Volume: 30 Pages: 615-623
- Data Source
  KAKENHI-PROJECT-26460538
[Patent] サーチュイン１遺伝子の発現増強剤2014
- Inventor(s)
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Holder
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-262048
- Filing Date
  2014-01-22
- Data Source
  KAKENHI-PROJECT-23580183
[Patent] サーチュイン1遺伝子の発現増強剤2013
- Inventor(s)
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Holder
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-013933
- Filing Date
  2013-01-29
- Overseas
- Data Source
  KAKENHI-PROJECT-23580183
[Patent] サーチュイン１遺伝子の発現増強剤2013
- Inventor(s)
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Holder
  長岡功、五十嵐庸、坂本廣司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-013933
- Filing Date
  2013-01-29
- Data Source
  KAKENHI-PROJECT-23580183
[Patent] アナンダミド生成抑制2005
- Inventor(s)
  長岡功
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Number
  2005-176312
- Filing Date
  2005-06-16
- Data Source
  KAKENHI-PROJECT-17590401
[Patent] アポトーシス抑制剤2005
- Inventor(s)
  長岡功
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Number
  2005-339395
- Filing Date
  2005-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Patent] 抗菌性ペプチド2004
- Inventor(s)
  長岡功
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Number
  2004-199835
- Filing Date
  2004-07-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590400
[Presentation] ヒト抗菌ペプチドLL-37 が血管内皮細胞のオートファジーおよび細胞死に及ぼす影響2020
- Author(s)
  鈴木　香, 大熊　真理, 長岡　功
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07545
[Presentation] ヒト抗菌ペプチドLL-37 が血管内皮細胞のオートファジーおよび細胞死に及ぼす影響2020
- Author(s)
  鈴木　香, 大熊真理, 長岡　功
- Organizer
  93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Antimicrobial peptide LL-37 induces antibacterial ectosomes from neutrophils2020
- Author(s)
  熊谷由美, 村上泰介, 桑原京子, 長岡　功
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 生体防御ペプチドLL-37 の敗血症モデルに対する保護効果2020
- Author(s)
  長岡　功, 熊谷　由美, 細田　浩司, 村上　泰介, 鈴木　香
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 生体防御ペプチドLL-37 の敗血症モデルに対する保護効果2020
- Author(s)
  長岡　功, 熊谷由美, 細田浩司, 村上泰介, 鈴木　香
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Antimicrobial peptide LL-37 induces antibacterial ectosomes from neutrophils2020
- Author(s)
  熊谷　由美, 村上　泰介, 桑原　京子, 長岡　功
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンによるIKKβの活性抑制を介したNF-κBの制御2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第17回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-18K05479
[Presentation] 機能性食品の軟骨代謝に及ぼす影響2019
- Author(s)
  長岡　功, 鶴田曉史, 堀池　巧, 吉村雅文
- Organizer
  日本農芸化学会2019年度(平成31年度)大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] グルコサミンによるNF-κB抑制メカニズムの解析2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第26回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-18K05479
[Presentation] グルコサミンはO-N-アセチルグルコサミン修飾を介してIκBα分解を抑制しNF-κB作用を阻害する2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K05479
[Presentation] 抗菌ペプチドLL-37は好中球からの細胞外小胞の放出を介してマウス敗血症を改善する2019
- Author(s)
  熊谷　由美, 村上　泰介, 長岡　功
- Organizer
  第66回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 軟骨細胞におけるグルコサミンのオートファジー誘導に関する機能解析2019
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] 抗菌ペプチドLL-37による好中球細胞外（エクトソーム）の放出を介したマウス敗血症の病態改善2019
- Author(s)
  熊谷　由美, 村上　泰介, 桒原　京子, 長岡　功
- Organizer
  第6回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Antimicrobial peptide LL-37 induces antibacterial ectosomes from neutrophils2019
- Author(s)
  熊谷由美, 村上泰介, 桑原京子, 長岡　功
- Organizer
  第93回日本細菌学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07562
[Presentation] 抗菌ペプチドLL-37による好中球細胞外（エクトソーム）の放出を介したマウス敗血症の病態改善2019
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, 長岡　功
- Organizer
  第6回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 軟骨細胞におけるグルコサミンによるオートファジー誘導に関する機能解析2019
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Organizer
  第26回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] 老化血管内皮細胞におけるLPS応答の増強効果2019
- Author(s)
  鈴木　香, 大熊真理, 長岡　功
- Organizer
  第25回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 老化血管内皮細胞におけるLPS応答の増強効果2019
- Author(s)
  鈴木　香, 大熊　真理, 長岡　功
- Organizer
  第25回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37が血管内皮細胞のオートファジーおよび細胞死に及ぼす影響2019
- Author(s)
  鈴木　香, 大熊真理, 長岡　功
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 抗菌ペプチドLL-37は好中球からの細胞外小胞の放出を介してマウス敗血症を改善する2019
- Author(s)
  熊谷由美, 村上泰介, 長岡　功
- Organizer
  第66回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-19K07562
[Presentation] MrgX2 を介した抗菌ペプチドLL-37 のマスト細胞内への移行と脱顆粒2019
- Author(s)
  村上　泰介, 鈴木　香, 長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 軟骨細胞におけるグルコサミンによるオートファジー誘導に関する機能解析2019
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Organizer
  第17回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] 滑膜細胞におけるグルコサミンの転写因子NF-κBの制御機構2019
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第15回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05479
[Presentation] グルコサミンと健康－グルコサミンの軟骨保護作用と抗炎症作用2019
- Author(s)
  長岡　功
- Organizer
  第14回ファンクショナルフード学会・研修会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] MrgX2 を介した抗菌ペプチドLL-37 のマスト細胞内への移行と脱顆粒2019
- Author(s)
  村上泰介, 鈴木　香, 長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 抗菌ペプチドLL-37は好中球からの細胞外小胞の放出を介してマウス敗血症を改善する2019
- Author(s)
  熊谷由美, 村上泰介, 長岡　功
- Organizer
  第66回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 軟骨細胞におけるグルコサミンのオートファジー誘導に関する機能解析2019
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Antimicrobial peptide LL-37 ameliorates mouse sepsis through microparticle release from neutrophils2019
- Author(s)
  熊谷　由美, 村上　泰介, 桑原　京子, 長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンの軟骨細胞におけるオートファジー誘導に関する機能解析2019
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Organizer
  第15回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Recent aspects of the chondroprotective and antiinflammatory actions of glucosamine, a chitosan monomer.2019
- Author(s)
  Nagaoka I
- Organizer
  The 29th Annual Meeting & International Symposium, The Korean Society for Chitin and Chitosan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Antimicrobial peptide LL-37 ameliorates mouse sepsis through microparticle release from neutrophils2019
- Author(s)
  熊谷由美, 村上泰介, 桑原京子, 長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 老化血管内皮細胞におけるLPS炎症応答の増幅効果2019
- Author(s)
  鈴木　香, 長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 抗菌ペプチドLL-37による好中球細胞外（エクトソーム）の放出を介したマウス敗血症の病態改善2019
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, 長岡　功
- Organizer
  第6回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-19K07562
[Presentation] 生体防御ペプチドLL-37 の敗血症モデルに対する保護効果2019
- Author(s)
  長岡　功, 熊谷由美, 細田浩司, 村上泰介, 鈴木　香
- Organizer
  第93回日本細菌学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07562
[Presentation] アスリートの軟骨代謝に及ぼす機能性食品の効果2019
- Author(s)
  長岡　功
- Organizer
  第24回ifia JAPAN 2019（国際食品素材/添加物展・会議）・第17回HFE JAPAN 2019（ヘルスフードエキスポ）
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] ヒト抗菌ペプチドLL-37が血管内皮細胞のオートファジーおよび細胞死に及ぼす影響2019
- Author(s)
  鈴木　香, 大熊　真理, 長岡　功
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07545
[Presentation] 老化血管内皮細胞におけるLPS炎症応答の増幅効果2019
- Author(s)
  鈴木　香,長岡　功
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Analysis of the components of neutrophil-derived microparticles with antibacterial activity.2018
- Author(s)
  Li Yan，熊谷由美，鈴木　香，長岡　功
- Organizer
  第91回日本細菌学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Involvement of MrgX2-mediated LL-37 internalization in degranulation of human mast cells.2018
- Author(s)
  村上泰介，鈴木　香，長岡　功
- Organizer
  第91回日本細菌学会総会（福岡）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンはO-GlcNAc修飾を介してNF-κBの活性化と核移行を抑制する2018
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] 宿主細胞の細胞死に注目した、抗菌ペプチドLL-37の敗血症マウスモデルに対する効果2018
- Author(s)
  長岡　功
- Organizer
  第33回日本Shock学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンの軟骨細胞におけるオートファジー誘導における機能解析2018
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] グルコサミンの軟骨細胞におけるオートファジーに対する機能解析2018
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Organizer
  第18回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Antimicrobial peptide LL-37 induces microparticle release from neutrophils in a mouse sepsis model.2018
- Author(s)
  熊谷由美，Li Yan，村上泰介，田村弘志，長岡　功
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] グルコサミンの軟骨細胞におけるオートファジー誘導に関する機能解析2018
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Organizer
  第16回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Antimicrobial peptide LL-37 induces microparticle release from neutrophils in a mouse sepsis model.2018
- Author(s)
  熊谷由美，Li Yan，村上泰介，田村弘志，長岡　功
- Organizer
  第91回日本細菌学会総会（福岡）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37による血管内皮細胞のオートファジーと細胞死に対する作用2018
- Author(s)
  鈴木　香, 大熊真理, 長岡　功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Mas-related gene X2を介した、マスト細胞への抗菌ペプチドLL-37細胞内移行と脱顆粒応答.2018
- Author(s)
  村上泰介, 森林叔子, 鈴木　香, 長岡　功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Glucosamine modulates the activation of NF-κB via the O-linked-N-acetylglucosamine modification in synovial cells2018
- Author(s)
  Someya A, Sakamoto K, Nagaoka I
- Organizer
  14th International Chitin and Chitosan Conference, 12th Asia-Pacific Chitin and Chitosan Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] グルコサミンによるO-N-アセチルグルコサミン修飾を介したNF-κBの機能制御2018
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第25回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] Human cathelicidin peptide LL-37 ameliorates sepsis in a mouse model through induction of microparticles with antibacterial potential from neutrophils.2018
- Author(s)
  Kumagai Y, Murakami T, Reich J, Tamura H, Nagaoka I
- Organizer
  Joint Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] ヒト抗菌ペプチドLL-37による血管内皮細胞のオートファジーと細胞死に対する作用.2018
- Author(s)
  鈴木　香, 大熊真理, 長岡　功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] Human cathelicidin peptide LL-37 ameliorates sepsis in a mouse model through induction of microparticles with antibacterial potential from neutrophils.2018
- Author(s)
  Kumagai Y, Murakami T, Reich J, Tamura H, Nagaoka I
- Organizer
  2018 Joint Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Chondroprotective action of glucosamine, a chitosan monomer, on the joint health of athletes.2018
- Author(s)
  Nagaoka I
- Organizer
  14th ICCC/12th APCCS/32nd JSCCC
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 抗菌ペプチドLL-37による好中球細胞外小胞（エクトソーム）の産生を介したマウス敗血症の病態改善2018
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, Reich Johannes, 田村弘志, 長岡　功
- Organizer
  第24回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンの軟骨細胞におけるオートファジーに対する機能解析2018
- Author(s)
  五十嵐庸、中村果歩、坂本廣司、長岡功
- Organizer
  第14回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] 軟骨細胞におけるグルコサミンによるサーチュイン1を介したオートファジー誘導に関する機能解析2018
- Author(s)
  五十嵐庸, 中村果歩, 坂本廣司, 長岡功
- Organizer
  第25回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Yokukansan, Japanese Herbal Medicine, Suppresses the Substance P-induced Production of IL-6 and IL-8 in Human U373 MG Cells2018
- Author(s)
  Yamaguchi K, Hamaoka S, Iseki M, Nagaoka I
- Organizer
  17th World Congress on Pain, Boston
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10564
[Presentation] 好中球細胞外小胞の産生を介したLL-37によるマウス敗血症の病態改善2018
- Author(s)
  熊谷由美, 村上泰介, 桑原京子, 射場敏明, 長岡　功
- Organizer
  第101回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 宿主細胞の細胞死に注目した、抗菌ペプチドLL-37の敗血症マウスモデルに対する効果.2018
- Author(s)
  長岡　功
- Organizer
  第33回日本Shock学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 好中球細胞外小胞の産生を介したLL-37によるマウス敗血症の病態改善.2018
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, 射場敏明, 長岡　功
- Organizer
  第101回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 抗菌ペプチドLL-37による好中球細胞外小胞（エクトソーム）の産生を介したマウス敗血症の病態改善.2018
- Author(s)
  熊谷由美, 村上泰介, 桒原京子, Reich Johannes, 田村弘志, 長岡　功
- Organizer
  第24回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] ヒト抗菌ペプチド LL-37 による血管内皮細胞のオートファジー誘導.2018
- Author(s)
  鈴木　香，大熊真理，長岡　功
- Organizer
  第91回日本細菌学会総会（福岡）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells.2018
- Author(s)
  Murakami T, Suzuki K, Niyonsaba F, Reich J, Tamura H, Nagaoka I
- Organizer
  oint Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] グルコサミンによる転写因子NF-κBの活性化抑制の作用メカニズム2018
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第18回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] Mas-related gene X2を介した、マスト細胞への抗菌ペプチドLL-37細胞内移行と脱顆粒応答2018
- Author(s)
  村上泰介, 森林叔子, 鈴木　香, 長岡　功
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] グルコサミンによるNF-κB阻害タンパクであるIκBαの制御2018
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第16回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] Analysis of the components of neutrophil-derived microparticles with antibacterial activity.2018
- Author(s)
  Li Yan，熊谷由美，鈴木　香，長岡　功
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] ヒト抗菌ペプチド LL-37 による血管内皮細胞のオートファジー誘導.2018
- Author(s)
  鈴木　香，大熊真理，長岡　功
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells.2018
- Author(s)
  Murakami T, Suzuki K, Niyonsaba F, Reich J, Tamura H, Nagaoka I
- Organizer
  2018 Joint Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Functional analysis of glucosamine in the induction of autophagy in chondrocytes.2018
- Author(s)
  Igarashi M, Nakamura K, Sakamoto K, Nagaoka I
- Organizer
  14th ICCC/12th APCCS/32nd JSCCC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] Antimicrobial cathelicidin peptide LL-37 protects septic mice by modulating macrophage pyroptosis and neutrophil NETosis.2017
- Author(s)
  Nagaoka I, Hosoda H, Hu Z, Nakamura K, Murakami T, Tamura H, Reich J
- Organizer
  Society for Leukocyte Biology 50th Annual Meeting (Vancouver, Canada)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] NETs形成に注目した、抗菌ペプチドLL-37の敗血症マウスモデルに対する効果の検討.2017
- Author(s)
  長岡　功, 細田浩司, 中村果歩, 胡　忠双, 村上泰介, 鈴木　香, 田村弘志
- Organizer
  第23回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] グルコサミンの軟骨細胞におけるオートファジーに対する機能解析2017
- Author(s)
  五十嵐庸、坂本廣司、長岡功
- Organizer
  第24回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] 抗菌ペプチドLL-37はNET形成を誘導して敗血症マウスモデルの生存率を改善する.2017
- Author(s)
  細田浩司, 中村果歩, 胡　忠双, 田村弘志, 長岡　功
- Organizer
  第64回トキシンシンポジウム（兵庫）
- Invited
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37は血管内皮細胞にオートファジーを誘導する.2017
- Author(s)
  鈴木　香, 長岡　功
- Organizer
  第64回トキシンシンポジウム（兵庫）
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37 は血管内皮細胞にオートファジーを誘導する2017
- Author(s)
  鈴木　香, 田村弘志, 長岡　功
- Organizer
  第90回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] グルコサミンの軟骨細胞におけるオートファジーに対する機能解析2017
- Author(s)
  五十嵐庸、坂本廣司、長岡功
- Organizer
  第15回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-17K00880
[Presentation] ヒト抗菌ペプチドLL-37 による肝類洞内皮細胞のLPS 取り込み促進作用.2017
- Author(s)
  鈴木　香, 長岡　功
- Organizer
  第100回日本細菌学会関東支部会総会（東京）
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] NETs形成に注目した、抗菌ペプチドLL-37の敗血症マウスモデルに対する効果の検討.2017
- Author(s)
  長岡　功, 細田浩司, 中村果歩, 胡　忠双, 村上泰介, 鈴木　香, 田村弘志
- Organizer
  第23回日本エンドトキシン・自然免疫研究会（兵庫）
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Antimicrobial cathelicidin peptide LL-37 protects septic mice by modulating macrophage pyroptosis and neutrophil NETosis.2017
- Author(s)
  Nagaoka Isao, Hosoda Hiroshi, Hu Zhongshuang, Nakamura Kaho, Murakami Taisuke, Tamura Hiroshi, Johannes
- Organizer
  Society for Leukocyte Biology 50th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] 抗菌ペプチドLL-37 はNET形成を増加させマウスCLP敗血症モデルの生存期間を延長する2017
- Author(s)
  細田浩司, 中村果歩, 胡　忠双, 李　燕, 田村弘志, 長岡　功
- Organizer
  第90回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] Involvement of Mas-related genes X2 in the internalization of LL-37 into mast cells.2017
- Author(s)
  村上泰介, 鈴木香, 長岡　功
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37は血管内皮細胞にオートファジーを誘導する2017
- Author(s)
  鈴木香, 田村弘志, 長岡　功
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] ヒト抗菌ペプチドLL-37は血管内皮細胞のオートファジーを活性化する.2017
- Author(s)
  鈴木　香, 長岡　功
- Organizer
  第4回日本血管血流学会学術集会（福岡）
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Involvement of MrgX2 in the internalization of LL-37 and degranulation of LAD2 human mast cells.2017
- Author(s)
  Murakami T, Suzuki K, Nagaoka I
- Organizer
  Society for Leukocyte Biology 50th Annual Meeting (Vancouver, Canada)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 抗菌ペプチドLL-37はNET形成を誘導して敗血症マウスモデルの生存率を改善する.2017
- Author(s)
  細田浩司, 中村果歩, 胡　忠双, 田村弘志, 長岡　功
- Organizer
  第64回トキシンシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K08840
[Presentation] グルコサミンによる転写因子NF-κBの活性化抑制の作用メカニズム2017
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第17回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] 滑膜細胞におけるグルコサミンによるO-GlcNAc修飾を介した転写因子NF-κBの抑制2017
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第15回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] Neutrophil extracellular traps (NETs) induces the IL-1β production by macrophages in combination with lipopolysaccharide2016
- Author(s)
  Hu Z, Suzuki K, Murakami T, Reich J, Tamura H, Nagaoka I
- Organizer
  14th Biennial Meeting International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] Neutrophil extracellular traps (NETs) induces the IL-1β production by macrophages in combination with lipopolysaccharide.2016
- Author(s)
  Hu Z, Suzuki K, Murakami T, Reich J, Tamura H, Nagaoka I
- Organizer
  14th Biennial Meeting International Endotoxin and Innate Immunity Society
- Place of Presentation
  Hamburg
- Year and Date
  2016-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] 抗菌ペプチドLL-37によるマスト細胞の活性化機序.2016
- Author(s)
  村上泰介, 鈴木香, 森林淑子, 長岡　功
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] The mechanism for a cathelicidin peptide LL-37-mediated LPS uptake by liver sinusoidal endothelial cells.2016
- Author(s)
  Suzuki K, Murakami T, Nagaoka I
- Organizer
  14th Biennial Meeting International Endotoxin and Innate Immunity Society
- Place of Presentation
  Hamburg
- Year and Date
  2016-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08789
[Presentation] Neutrophil extracellular traps (NETs) induces the IL-1β production by macrophages.2016
- Author(s)
  Hu Zhongshuang，鈴木　香，田村　弘志，長岡　功
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] The mechanism for a cathelicidin peptide LL-37-mediated LPS uptake by liver sinusoidal endothelial cells2016
- Author(s)
  Suzuki K, Murakami T, Nagaoka I
- Organizer
  14th Biennial Meeting International Endotoxin and Innate Immunity Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] グルコサミンは滑膜細胞からの炎症促進分子の発現・産生を抑制する2016
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第30回キチン・キトサン学会
- Place of Presentation
  埼玉県　ウエスタ川越
- Year and Date
  2016-08-18
- Data Source
  KAKENHI-PROJECT-15K00844
[Presentation] NETs (neutrophil extracellular traps) induce IL-1β production by macrophages in the presence of lipopolysaccharide.2015
- Author(s)
  Hu Z, Suzuki K, Tamura H, Nagaoka I
- Organizer
  48Th Annual Meeting of the Society for Leukocyte Biology
- Place of Presentation
  Hilton North Raleigh, NC, USA
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] NETs (neutrophil extracellular traps) induces the the IL-1β production by macrophages.2015
- Author(s)
  Hu Z, Suzuki K, Tamura H, Nagaoka I
- Organizer
  第21回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  がん研有明病院（東京）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] The role of NETs (neutrophil extracellular traps) in the IL-1β production by macrophages.2015
- Author(s)
  Hu Z, Suzuki K, Tamura H, Nagaoka I
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センターミレニアムホール（東京）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] マクロファージ系細胞におけるIL-1β産生に対するNETs (neutrophil extracellular traps)の作用.2015
- Author(s)
  胡　忠双, 鈴木　香, 田村弘志, 長岡　功
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] A novel mechanism for the human host defense peptide LL-37-Induced mast cell degranulation.2015
- Author(s)
  Suzuki K, Murakami T, Moribayashi T, Nagaoka I
- Organizer
  48Th Annual Meeting of the Society for Leukocyte Biology
- Place of Presentation
  Hilton North Raleigh, NC, USA
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] The role of NETs (neutrophil extracellular traps) in the IL-1β production by macrophages.2015
- Author(s)
  Hu Z, Suzuki K, Tamura H, Nagaoka I
- Organizer
  第98回日本細菌学会関東支部会総会
- Place of Presentation
  東京歯科大学血脇ホール（東京）
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] Mechanism for the lipopolysaccharide-induced release of high mobility group nucleosome-binding domain-1 from murine macrophage like RAW264.7.2015
- Author(s)
  Murakami T, Hu Z, Suzuki K, Tamura H, Nagaoka I
- Organizer
  48Th Annual Meeting of the Society for Leukocyte Biology
- Place of Presentation
  Hilton North Raleigh Midtown hotel,Raleigh, NC, US
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590535
[Presentation] The effects of antimicrobial peptide LL-37 on the pyroptosis of macrophages and a polymicrobial sepsis model2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I
- Organizer
  The 12th Japan-Korea International Symposium on Microbiology 2014
- Place of Presentation
  Tokyo, (Program & Abstracts 58)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] LL-37 enhances the LPS uptake without cell activation in endothelial cells.2014
- Author(s)
  Suzuki K, Nagaoka I
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] グルコサミンは散骨細胞においてサーチュイン１の遺伝子発現を亢進する2014
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第１４回日本抗加齢医学会総会
- Place of Presentation
  大阪国際会議場（大阪府)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 機能性ペプチド（特に生体防御ペプチド）の構造と多様性. ペプチド研究の新潮流. “未来へのバイオ技術”勉強会.2014
- Author(s)
  長岡　功
- Organizer
  バイオインダストリー協会（JBA）バイオセミナーシリーズ.
- Place of Presentation
  バイオインダストリー協会（東京）
- Year and Date
  2014-11-17
- Invited
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] The effects of LL-37 on the LPS/ATP-induced pyroprosis of macrophages and a murine sepsis model2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京, (日本細菌学会雑誌69: 137)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Antimicrobial peptide LL-37 enhances the LPS uptake without cell activation in endothelial cells2014
- Author(s)
  Suzuki K, Nagaoka I
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京, (日本細菌学会雑誌69: 185)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] グルコサミンはサーチュイン1の遺伝子発現を亢進する2014
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第14回日本加齢医学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] グルコサミンとN−アセチルグルコサミンは軟骨細胞においてサーチュイン1の遺伝子発現を亢進する2014
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第10回グルコサミン研究会学術集会
- Place of Presentation
  国立オリンピック記念青少年総合センター(東京都)
- Year and Date
  2014-02-15
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] Human antimicrobial peptide LL-37 enhances the LPS uptake without cell activation in endothelial cells2014
- Author(s)
  Suzuki K, Tamura H, Nagaoka I
- Organizer
  The 12th Japan-Korea International Symposium on Microbiology 2014
- Place of Presentation
  Tokyo, (Program & Abstracts 59)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] The effects of LL-37 on the LPS/ATP-induced pyroprosis of macrophages and a murine sepsis model.2014
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] サーチュイン１は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第２０回日本未病システム学会学術集会
- Place of Presentation
  学術総合センター（東京都)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第9回グルコサミン研究会学術集会
- Place of Presentation
  順天堂大学医学部有山登記念館講堂(東京都)
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] サーチュイン１は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第１１回日本機能性食品医用学会総会
- Place of Presentation
  東京海洋大学品川キャンパス（東京都)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 滑膜細胞からのIL-8産生に対するグルコサミンの分子抑制メカニズム2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] LPS/ATPで誘導されるピロトーシスに対する抗菌ペプチドLL-37の効果と作用機構.2013
- Author(s)
  胡　忠双, 村上　泰介, 鈴木　香, 田村　弘志, 長岡　功
- Organizer
  第19回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] 抗菌ペプチドLL-37によるマクロファージピロトーシスの制御.2013
- Author(s)
  胡　忠双, 村上　泰介, 鈴木　香, 田村　弘志, 長岡　功
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] マクロファージ系細胞のピロトーシスに対する抗菌ペプチドLL-37の制御作用.2013
- Author(s)
  胡　忠双, 村上　泰介, 鈴木　香, 田村　弘志, 長岡　功
- Organizer
  第13回日本AS学会/第7回日本血流血管学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Sirtuin 1 is a target gene of glucosamine in chondrocyte2013
- Author(s)
  Igarashi M, Suzuki K, Someya A, Sakamoto K, Nagaoka I.
- Organizer
  10th Asia-Pacific Chitin & Chitosan Symposium
- Place of Presentation
  米子コンベンションセンター(鳥取県)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism.2013
- Author(s)
  Nagaoka I, Hu Z, Murakami T, Suzuki K, Tamura H
- Organizer
  Mechanisms and Functions of Non-apoptotic Cell Death, The 2013 Cold Spring Harbor Asia Conference
- Place of Presentation
  Suzhou, China
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] サーチュイン１は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] グルコサミンは転写因子Sp1のO-N-アセチルグルコサミン修飾を介してIL-8の発現を抑制する2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第20回日本未病システム学会学術総会
- Place of Presentation
  東京、学術総合センター
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第11回日本機能性食品医用学会総会
- Place of Presentation
  東京海洋大学品川キャンパス(東京都)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 生体防御ペプチドによるLPSシグナルの制御2013
- Author(s)
  鈴木香,長岡功
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉, (日本細菌学会雑誌68: 90)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Glucosamine suppresses IL-8 expression through the O-N-acetylglucosamine modification of transcription factor Sp1 in synovial cells2013
- Author(s)
  Someya A, Sakamoto K, Nagaoka I.
- Organizer
  10th Asia-pacific Chitin and chitosan Symposium
- Place of Presentation
  米子、米子コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] Dual mechanism of antimicrobial cathelicidin peptide LL-37 for the inhibition of LPS/ATP-induced pyroptosis.2013
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Sirtuin 1 is a target gene of glucosamine in chondrocytes.2013
- Author(s)
  M. Igarashi, K. Suzuki, A. Someya, K. Sakamoto, I. Nagaoka
- Organizer
  10th Asia-Pacific Chitin & Chitosan Symposium
- Place of Presentation
  米子コンベンションセンター（鳥取県）
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] グルコサミンによる転写因子Sp1のO-N-アセチルグルコサミン修飾とIL-8発現の抑制2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  京都、京都国際会議場
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] グルコサミンによる転写因子Sp1のO-N-アセチルグルコサミン修飾の亢進2013
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第9回グルコサミン研究会学術集会
- Place of Presentation
  東京、順天堂大学有山記念講堂
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] 抗菌ペプチドLL-37は二つのメカニズムによってLPS/ATPで誘導されるピロトーシスを抑制する.2013
- Author(s)
  胡　忠双, 村上　泰介, 鈴木　香, 田村　弘志, 森田隆司, 長岡　功
- Organizer
  第60回トキシンシンポジウム
- Place of Presentation
  宍粟
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である2013
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第20回日本未病システム学会学術集会
- Place of Presentation
  学術総合センター(東京都)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 滑膜細胞における遺伝子発現とO-N-アセチルグルコサミン修飾に及ぼすグルコサミンの網羅的解析2012
- Author(s)
  染谷明正, 五十嵐　庸, 坂本廣司, 長岡　功
- Organizer
  第26回キチン・キトサンシンンポジウム
- Place of Presentation
  札幌、北海道大学学術交流会館
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] 滑膜細胞の遺伝子発現に及ぼすグルコサミンの影響と糖鎖修飾の関与2012
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  福岡、ホテル日航福岡
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] 滑膜細胞におけるグルコサミンの遺伝子発現制御メカニズム2012
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡、福岡国際会議場･マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] グルコサミンによる滑膜炎症の分子制御メカニズム2012
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第19回日本未病システム学会学術総会
- Place of Presentation
  金沢、金沢勤労者プラザ
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] 生体防御ペプチドによる宿主細胞のアポトーシス制御2012
- Author(s)
  長岡功,鈴木香,田村弘志
- Organizer
  第21回日本Cell Death学会
- Place of Presentation
  名古屋, (プログラム予稿集27)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Modulation of the LPS/ATP-induced pyroptosis of macrophages by antimicrobial cathelicidin peptide LL-372012
- Author(s)
  Hu Z, Murakami T, Suzuki K, Nagaoka I
- Organizer
  The 12th Biennial International Endotoxin & Innate Immunity Society Meeting
- Place of Presentation
  Tokyo, (IEIIS2012 Program & Abstract : 174)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] 抗菌ペプチドによる好中球アポトーシスの制御.2011
- Author(s)
  長岡　功
- Organizer
  第58回毒素シンポジウム(招待講演)
- Place of Presentation
  順天堂大学（東京）
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation2011
- Author(s)
  Igarashi M, Sakamoto K, Nagaoka I.
- Organizer
  The 9th Asia-Pacific Chitin and Symposium
- Place of Presentation
  Yasaka Saigon Nha Trang Hotel(ニャチャン、ベトナム社会主義共和国)
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] Antimicrobial peptides, human defensins and LL-37, modulate neutrophil apoptosis2011
- Author(s)
  Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M
- Organizer
  International Union of Microbiological Societies 2011 Congress (IUMS2011)
- Place of Presentation
  Sapporo, (Program 131)
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Antimicrobial peptides, human defensins and LL-372011
- Author(s)
  Isao Nagaoka
- Organizer
  IUMS2011
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] 抗菌ペプチドによる好中球アポトーシスの制御.2011
- Author(s)
  長岡　功
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation.2011
- Author(s)
  Igarashi M, Sakamoto K and Nagaoka I
- Organizer
  The 9th Asia-Pacific Chitin and Chitosan Symposium
- Place of Presentation
  ベトナム社会主義共和国ニャチャン
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] LPSで誘導される血管内皮細胞のアポトーシスに対するヒト抗菌ペプチドLL-37の抑制効果2010
- Author(s)
  鈴木香,栞原京子,射場敏明,山倉文幸,田村弘志,村上泰介,細田浩司,長岡功
- Organizer
  第57回毒素シンポジウム予稿集(60-62)
- Place of Presentation
  長浜
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] 敗血症モデルマウスにおける肝血管内皮細胞アポトーシスに対する抗菌ペプチドLL-37の効果2010
- Author(s)
  鈴木香,村上泰介,田村弘志,長岡功
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(2P-1039)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] ヒトα-デフェンシンによる好中球アポトーシスの制御2010
- Author(s)
  長岡功,鈴木香,村上泰介,細田浩司,田村弘志
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)(2P-1040)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] An antimicrobial cathelicidin peptide LL-37 suppresses the LPS-induced endothelial cell apoptosis. The three Rs of immunity : recognition, response and resolution.2010
- Author(s)
  Suzuki K, Murakami T, Tamura H, Nagaoka I
- Organizer
  109, Annual Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] Evaluation of the effect of alpha-defensins human neutrophil peptides on neutrophil apoptosis. The three Rs of immunity : recognition, response and resolution.2010
- Author(s)
  Nagaoka I, Suzuki K, Murakami T, Niyonsaba F, Tamura H, Hirata M
- Organizer
  63, Annual Meeting of the Society for Leukocyte Biology & the International Endotoxin and Innate Immunity Society
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] Antimicrobial cathelicidin peptide CAP11 suppresses HMGB1 (high mobility group box-1) release from lipopolysaccharide-stimulated mononuclear phagocytes via the prevention of necrotic cell death.2009
- Author(s)
  Nagaoka I, Shibusawa K, Murakami T, Tamura H
- Organizer
  Cytokine 48 : 97, Tri-Society Annual Conference
- Place of Presentation
  Lisbon
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] 抗菌ペプチドCAP11によるマクロファージ様細胞からのHMGB1の放出制御機構2009
- Author(s)
  長岡功,渋沢澤謙太郎,村上泰介,鈴木香,田村弘志
- Organizer
  第56回毒素シンポジウム予稿集(122-127)
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] LPS刺激によるマクロファージ様細胞からのHMGB1放出と抗菌ペプチドCAP11の抑制効果2009
- Author(s)
  長岡功
- Organizer
  第3回日本血流血管学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] Cathelicidinファミリー抗菌ペプチドLL-37はLPSで誘導される血管内皮細胞のアポトーシスを抑制する2009
- Author(s)
  鈴木香,渋沢謙太郎,栞原京子,射場敏明,山倉文幸,田村弘志,長岡功
- Organizer
  生化学81:200,396,第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] Antimicrobial cathelicidin peptide CAP11 suppresses HMGB1(high mobility group box-1)release from lipopolysaccharide-stimulated mononuclear phagocytes via the prevention of necrotic cell death2009
- Author(s)
  長岡功
- Organizer
  Tri-Society Annual Conference
- Place of Presentation
  Lisbon
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] 敗血症性ショックにおける抗菌ペプチドCAP11によるHMGB1の放出制御2008
- Author(s)
  渋沢謙太郎,村上泰介,田村弘志,長岡功
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会講演要旨集:822
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590456
[Presentation] Inhibitory effects of antimicrobial cathelicidin peptide CAP11 on the production and release of anandamide and HMGB1 in an endotoxin shock model. MBM2007 Abstract : 8562007
- Author(s)
  Murakami, T, Okuda, D, Yomogida, S, Tamura, H, Nagaoka, I
- Organizer
  MBM2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Evaluation of the effects of antimicrobial cathelicidin peptide CAP11 on the production and release of anandamide and HMGB 1 in an endotoxin shock model. J Leukoc Biol Suppl : 272007
- Author(s)
  Murakami, T, Yomogida, S, Shibusawa, K, Okuda, D, Tamura, H, Nagaoka, I
- Organizer
  40th Annual Meeting of the Society for Leukocyte Biology
- Place of Presentation
  Massachusetts
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Regulationof neutrophil apoptosis by antimicrobial human β-defensins. MBM2007 Abstract : 8562007
- Author(s)
  Nagaoka, I, Niyonsaba, F, Tsutsumi-Ishii, Y, Tamura, H, Hirata, M
- Organizer
  MBM2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Bactericidal and LPS-neutralizing activities of antimicrobial cathelicidin peptides, CAP 18/LL-37 and CAP11. The 5th Glucan Workshop2006
- Author(s)
  Nagaoka, I
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Suppressive effects of antibacterial cathelicidin peptide CAP 11 on the anandamide production from LPS-stimulated mononuclear phagocytes. J Leukoc Biol Suppl : 372006
- Author(s)
  Murakami, T, Okuda, D, Yomogida, S, Tamura, H, Nagaoka, I
- Organizer
  Joint conference of the Society for Leukocyte Biology 39th Annual Meeting and International Endotoxin and Innate Immunity Society 9th Biennial Meeting, San Antonio
- Place of Presentation
  Texas
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Antimicrobial human beta-defensin-3 suppresses neutrophil apoptosis via the action on CCR6. J Leukoc Biol Suppl : 782006
- Author(s)
  Nagaoka, I, Tsutsumi-Ishii, Y, Tamura, H, Hirata, M
- Organizer
  Joint conference of the Society for Leukocyte Biology 39th Annual Meeting and International Endotoxin and Innate Immunity Society 9th Biennial Meeting, San Antonio
- Place of Presentation
  Texas
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Antibacterial cathelicidin peptide human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X7. J Leukoc Biol Suppl : 562005
- Author(s)
  Nagaoka, I, Tsutsumi-Ishii, Y, Tamura, H, Hirata, M
- Organizer
  Society for Leukocyte Biology 38th Annual Meeding
- Place of Presentation
  Oxford, UK
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Antibacterial cathelicidin peptide human CAP18/LL-37 suppresses neutrophil apoptosis via the activation of FPRL1 and P2X72005
- Author(s)
  Nagaoka Isao
- Organizer
  38th Annual Meeting of the Society for Leukocyte Biology
- Place of Presentation
  Oxford,UK
- Year and Date
  2005-09-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590401
[Presentation] Antimicrobial peptide LL-37 inhibits pyroptosis of macrophages and protects sepsis in a murine model.
- Author(s)
  Hu Z, Murakami T, Suzuki K, Tamura H, Nagaoka I
- Organizer
  Joint Meeting of the Society for Leukocyte Biology and the Interntional Endotoxin and Innate Immunity Society
- Place of Presentation
  Salt Lake (USA)
- Year and Date
  2014-10-23 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] サーチュイン1は軟骨細胞におけるグルコサミンの標的遺伝子である
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第９回グルコサミン研究会学術集会
- Place of Presentation
  順天堂大学医学部有山登記念館講堂
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 抗菌ペプチドLL-37によるマクロファージの細胞死ピロトーシスの制御.
- Author(s)
  胡　忠双, 村上　泰介, 鈴木　香, 田村　弘志, 長岡　功
- Organizer
  第61回トキシンシンポジウム
- Place of Presentation
  ルネッサンスリゾートナルト（鳴門）
- Year and Date
  2014-09-03 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] Human host defense peptide LL-37 enhances the LPS uptake by endothelial cells without cell activation: a possible role in the LPS clearance.
- Author(s)
  Suzuki K, Hu Z, Tamura H, Nagaoka I
- Organizer
  Joint Meeting of the Society for Leukocyte Biology and the Interntional Endotoxin and Innate Immunity Society
- Place of Presentation
  Salt Lake (USA)
- Year and Date
  2014-10-23 – 2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] Cathelicidinファミリーの抗菌ペプチドLL-37によるエンドトキシン除去作用.
- Author(s)
  鈴木　香, 村上泰介, 胡　忠双, 細田浩司, 長岡　功
- Organizer
  第20回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  順天堂大学（東京）
- Year and Date
  2014-12-05 – 2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] 生体防御ペプチドによる宿主細胞のアポトーシス制御.
- Author(s)
  長岡　功
- Organizer
  第21回日本Cell Death学会
- Place of Presentation
  名古屋大学医学部（愛知県）
- Invited
- Data Source
  KAKENHI-PROJECT-23590519
[Presentation] グルコサミンは転写因子Sp1の細胞内局在をO-N-アセチルグルコサミン修飾を介して調節する
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第26回キチン・キトサンシンンポジウム
- Place of Presentation
  東京、順天堂大学本郷・お茶の水キャンパス
- Year and Date
  2014-08-07 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] 滑膜細胞からのIL-8産生に対するグルコサミンの分子抑制メカニズム
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] NETs (neutrophil extracellular traps) induce the IL-1β production by macrophages.
- Author(s)
  胡　忠双, 鈴木　香, 田村弘志, 長岡　功
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] グルコサミンによる転写因子Sp1の糖鎖修飾を介したIL-8産生制御機構
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第12回機能性食品医用学会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] Cell surface HS proteoglycans mediate the uptake of antimicrobial peptide LL-37-LPS complex by LSECs.
- Author(s)
  鈴木　香, 田村弘志, 長岡　功
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] 滑膜細胞におけるグルコサミンによる転写因子Sp1の制御機構について
- Author(s)
  染谷明正, 坂本廣司, 長岡　功
- Organizer
  第21回日本未病システム学会学術総会
- Place of Presentation
  大阪、千里ライフサイエンスセンター
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] Potential effects of human antimicrobial peptide LL-37 on macrophage pyroptosis and sepsis.
- Author(s)
  Nagaoka I, Hu Z, Suzuki K, Tamura H
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] 滑膜細胞の遺伝子発現に対するグルコサミンの影響
- Author(s)
  染谷明正、坂本廣司、長岡　功
- Organizer
  第8回グルコサミン研究会学術集会
- Place of Presentation
  学校法人城西大学　東京紀尾井町キャンパス　ホール
- Data Source
  KAKENHI-PROJECT-23592232
[Presentation] グルコサミンおよびN-アセチルグルコサミンは散骨細胞においてサーチュイン１の遺伝子発現を亢進する
- Author(s)
  五十嵐庸、鈴木香、坂本廣司、長岡功
- Organizer
  第１０回グルコサミン研究会学術集会
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都）
- Data Source
  KAKENHI-PROJECT-23580183
[Presentation] 血管内皮細胞によるLPSの取り込みに対するヒト抗菌ペプチドLL-37の促進作用.
- Author(s)
  鈴木　香, 胡　忠双, 田村　弘志, 長岡　功
- Organizer
  第61回トキシンシンポジウム
- Place of Presentation
  ルネッサンスリゾートナルト（鳴門）
- Year and Date
  2014-09-03 – 2014-09-05
- Invited
- Data Source
  KAKENHI-PROJECT-26460538
[Presentation] 抗菌ペプチドLL-37によるマクロファージのピロトーシス制御.
- Author(s)
  胡　忠双, 村上泰介, 鈴木　香, 田村弘志, 長岡　功
- Organizer
  第20回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  順天堂大学（東京）
- Year and Date
  2014-12-05 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-26460538

1. IBA Toshiaki (40193635)

# of Collaborated Projects: 8 results

# of Collaborated Products: 23 results
2. KUWAHARA Kyoko (10167976)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
3. SUZUKI Kaori (90631929)

# of Collaborated Projects: 4 results

# of Collaborated Products: 58 results
4. IGARASHI Mamoru (00277815)

# of Collaborated Projects: 3 results

# of Collaborated Products: 41 results
5. SOMEYA AKIMASA (90167479)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
6. YAMAGUCHI Keisuke (10338410)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. MURAKAMI Taisuke (40384135)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
8. 熊谷由美 (90277591)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. TABE Yoko (70306968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. FUKUDA Yutaka (40208971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 平田陸正 (20048359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小林滋 (70301497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 井関雅子 (80221076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 三田智也 (90532557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HU Zhongshuang

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
16. WAKABAYASHI saiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TADA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. SUGASAWA Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山口啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
20. 清水崇光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 浜窪隆雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 落合匠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. ニヨンサバフランソワ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

NAGAOKA Isao 長岡 功

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食品素材グルコサミンの脱アセチル化酵素サーチュインを介した新規軟骨保護作用の解明Ongoing

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Host defense peptide LL-37 modulates the pathogenesis of sepsis by inducing the release of exosomesPrincipal InvestigatorOngoing

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感染刺激によって放出される抗菌性ペプチドLL-37による動脈硬化の増悪機構Ongoing

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好中球細胞外小胞エクトソームの敗血症治療への応用を目指してOngoing

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機能性食品素材であるアセチルグルコサミンの抗炎症作用に関する分子メカニズムOngoing

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認知症のリスクファクターとしての慢性疼痛におけるサブスタンスＰの役割Ongoing

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機能性食品であるグルコサミンのオートファジーに対する新規作用の解明Ongoing

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好中球エクトソームと危険信号分子アラーミンに着目した敗血症の新たな病態制御Principal InvestigatorOngoing

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Roles of NETs and alarmins in the pathogenesis of sepsisPrincipal Investigator

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NAGAOKA Isao 長岡功