IWATANI Yoshinori 岩谷良則

… Alternative Names

岩谷良則イワタニヨシノリ

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Researcher Number	60168581
Other IDs	https://orcid.org/0000-0003-4371-0398
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 大阪大学, 医学系研究科, 名誉教授 2012 – 2016: 大阪大学, 医学(系)研究科(研究院), 教授 2008 – 2011: Osaka University, 医学系研究科, 教授 2010: Osaka University, 大学院・医学系研究科, 教授 2005 – 2006: 大阪大学, 医学系研究科, 教授 … More 2003: Osaka Univ., Osaka Univ. Graduate School of Medicine, Professor, 医学系研究科, 教授 2002: 大阪大学, 医学部, 教授 1996 – 2000: 大阪大学, 医学部, 教授 1994: Osaka Univ.Med.Sch., Dept.of Clin.Lab.Sci, Prof., 医学部, 教授 1992 – 1993: Osaka University,Medical School,Associate Professor, 医学部, 助教授 1990 – 1991: 大阪大学, 医学部, 講師 1986 – 1987: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / 内科学一般 / Laboratory medicine Except Principal Investigator Laboratory medicine / 内科学一般
Keywords	Principal Investigator 自己免疫疾患 / 甲状腺 / 遺伝子多型 / thyroid / サイトカイン / 重症度 / 一塩基多型 / 発症予知 / autoimmune disease / バセドウ病 … More / 橋本病 / 自己免疫性甲状腺疾患 / サイトカイン産生細胞 / マイクロRNA / 予防医学 / エピジェネティクス / TNFαメチル化 / Argonate / miR-27A / miR-146 / IL-18 / ＴＬＲ / 甲状腺自己抗原 / 予後予測 / Ｔｈ１７関連遺伝子 / Ｔｈ２走化性関連遺伝子 / ヨードサイロニン脱ヨウ素酵素 / ＴＮＦＡ遺伝子 / エピゲノム / ゲノム / メチル化 / ＶＥＧＦ/ＶＥＧＦＲ２遺伝子 / ＣＤ８０/ＣＤ８６遺伝子 / ＩＬ６遺伝子 / ＣＤ５８遺伝子 / ＩＦＮＧ遺伝子 / DNAメチル化 / 発症予測 / 病因・病態 / interleukin 10 / interleukin 2 / interferon gamma / intractability / severity / gene polymorphism / 遺伝子検査 / 予後 / サイトカインバランス / 予後診断 / インターロイキン10 / インターロイキン2 / インターフェロンγ / 難治度 / interleukin-10 (IL-10) / IgG3-secreting cells / CD50+CD8+ cells / CD25+CD8+ cells / CD25+CD4+ cells / deep vein thrombosis / autoimmune / CD30+CD8+細胞 / 樹状細胞 / NKT細胞 / CD25+CD4+細胞 / IgA / IgG3 / CD8 / CD4 / CD30 / 予後診断法 / インターロイキン10(IL-10) / IgG3産生細胞 / CD30^+CD8^+細胞 / CD25^+CD8^+細胞 / CD25^+CD4^+細胞 / 深部静脈血栓症 / enzyme immunoassay / image analysis / cytokine-producing cell / membrane proteins cells producing soluble / antibody-producing ell / immune function test / 免疫機能検査 / 酸素抗体法 / 細胞検出法 / 酵素抗体法 / 画像解析 / 可溶性膜蛋白産生細胞 / 抗体産生細胞 / 免疫機能検査法 / cytokine / apoptosis / peripheral tolerance / アポトーシス / 末梢トレランス / CD4^-CD8^- cells / CD4^+CD8^+ cells / Aggravation / Graves' disease / Hashimoto's disease / Thyroid / Infiltrating lymphocyte / Autoimmune disease / CD4^-CD8^-細胞 / CD4^+CD8^+細胞 / 増悪機序 / 組織浸潤リンパ球 / Autoimmune thyroid disease / Thyroid hormone / TSH receptor antibody / thyroid-peroxidase antibody / thyroglobulin antibody / CD5-B cells / CD5^+B cells / Autoantibodies / TSHレセプタ-抗体 / 甲状腺ペルオキシダ-ゼ抗体 / CD5^-Bリンパ球 / CD5^+Bリンパ球 / 甲状腺ホルモン / TSHレセプター抗体 / 甲状腺ペルオキシダーゼ抗体 / サイログロブリン抗体 / CD5^-リンパ球 / CD5^+リンパ球 / 臓器特異的自己抗体 / Standardization / Automation / ELISPOT assay / Cytokine-producing cells / Specific antibody-producing cells / 標準化 / 自動化 / ELISPOT法 / 特異抗体産生細胞 / マイクロＲＮＡ / Th2細胞 / Th1細胞 / マスター遺伝子 / MTRR / DNMT1 / FCRL3 / CD40 / ＥＰＯ / ＩＬ－１０ / ＣＤ２４ / DNAメチル化酵素 / 疾患感受性遺伝子 / 発症予知診断法 / 免疫応答制御因子 / HHEX / GITRL / Foxel / 甲状線 / FOXP3 / GITR / 発生制御因子 / 制御性T細胞 / 末梢性自己寛容 / 診断法 … More Except Principal Investigator バセドウ病 / Prediction of onset / Graves' disease / 出産後発症 / 発症予防 / 発症予測 / 橋本病 / 自己免疫疾患 / Hashimoto's disease / Screening / postpartum onset / Prevention of onset / Autoimmune disase / 膠原病 / スクリーニング / Autoantibodies / Postpartum / Pregnancy / Prevention / Hashimoto's thyroiditis / Autoimmune desease / 慢性関節リウマチ / 出産 / 妊娠 / 慢性関節リュウマチ / 自己抗体 / エンザイムイムノアッセイ / 受容体抗体 / オリゴペプチド / TSH受容体 Less

Development of the diagnostic methods to predict the development and the prognosis of autoimmune diseases based on the genome and epigenome informationsPrincipal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Diagnostic methods to predict the development and the prognosis of autoimmune diseases based on the reguratory mechanisms for gene expressionPrincipal Investigator
- Principal Investigator
  
  Iwatani Yoshinori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Diagnostic methods to predict the development of autoimmune diseases by gene polymorphisms of immune regulatory factorsPrincipal Investigator
- Principal Investigator
  
  YOSHINORI Iwatani
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Development of predictive diagnostic method for autoimmune diseases on the basis of the mechanism of peripheral self-tolerance inductionPrincipal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Development of predictive diagnostic method for autoimmune disease by gene polymorphisms of immunomodulatory factorsPrincipal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Development of the method to diagnose the prognosis of autoimmune disease by clarifying the pathologic factors.Principal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Development of a sensitive analyzer for multiple immune function.Principal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
Study on abnormalities of peripheral tolerance induction by target cells in organ-specific autoimmune diseases.Principal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
Prediction of postpartum onset of autoimmune disease and its prevention
- Principal Investigator
  
  AMINO Nobuyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Study on lymphocyte subsets infiltrating the target organ in autoimmune diseases.Principal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
合成オリゴペプチドを用いたTSH受容体抗体の免疫測定法の開発と臨床応用
- Principal Investigator
  
  AMINO Nobuyuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Development of an automatic high-sensitive assay system for cells producing a specific antibody or a cytokine.Principal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka University
Study on B cell subsets producing ongan-specific autoantibodiesPrincipal Investigator
- Principal Investigator
  
  IWATANI Yoshinori
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
Prediction and prevention of postpartum onset of autoimmune disease
- Principal Investigator
  
  AMINO Nobuyuki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University

[Book] 臨床検査学実習書シリーズ遺伝子検査学実習書2010
- Author(s)
  岩谷良則編
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Increases of CD80 and CD86 Expression on Peripheral Blood Cells and their Gene Polymorphisms in Autoimmune Thyroid Disease.2020
- Author(s)
  Watanabe A, Inoue N, Watanabe M, Yamamoto M, Ozaki H, Hidaka Y, Iwatani Y.
- Journal Title
  
  Immunol Invest
  
  Volume: 49(1-2) Issue: 1-2 Pages: 191-203
- DOI
  10.1080/08820139.2019.1688343
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-17K15774
[Journal Article] Association of CD58 Polymorphisms and its Protein Expression with the Development and Prognosis of Autoimmune Thyroid Diseases.2020
- Author(s)
  Yamamoto M, Watanabe M, Inoue N, Watanabe A, Ozaki H, Ohsaki M, Hidaka Y, Iwatani Y.
- Journal Title
  
  Immunol Invest
  
  Volume: 49(1-2) Issue: 1-2 Pages: 106-119
- DOI
  10.1080/08820139.2019.1659811
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-19H04048
[Journal Article] Gene polymorphisms of VEGF and VEGFR2 are associated with the severity of Hashimoto’s disease and the intractability of Graves’ disease, respectively2020
- Author(s)
 Okamoto M, Watanabe M, Inoue N, Ogawa K, Hidaka Y, Iwatani Y.
- Journal Title
 
 Endocr J
 
 Volume: 67 Issue: 5 Pages: 545-559
- DOI
 10.1507/endocrj.EJ19-0480
- NAID
 130007847996
- ISSN
 0918-8959, 1348-4540
- Language
 English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-20K07847, KAKENHI-PROJECT-19H04048
[Journal Article] Association of IL6 gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.2019
- Author(s)
  Hirai N, Watanabe M, Inoue N, Kinoshita R, Ohtani H, Hidaka Y, Iwatani Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 52(7-8) Issue: 7-8 Pages: 251-255
- DOI
  10.1080/08916934.2019.1669568
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-19H04048, KAKENHI-PROJECT-17K08982
[Journal Article] Association of IFNG gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.2019
- Author(s)
  Hashimoto H, Watanabe M, Inoue N, Hirai N, Haga E, Kinoshita R, Hidaka Y, Iwatani Y.
- Journal Title
  
  Cytokine
  
  Volume: 123 Pages: 154770-154770
- DOI
  10.1016/j.cyto.2019.154770
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-19H04048
[Journal Article] Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases2018
- Author(s)
  Tokiyoshi Ena、Watanabe Mikio、Inoue Naoya、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Autoimmunity
  
  Volume: 51 Issue: 1 Pages: 35-42
- DOI
  10.1080/08916934.2017.1416468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-16H03261
[Journal Article] Functional polymorphisms of the type 1 and type 2 iodothyronine deiodinase genes in autoimmune thyroid diseases2018
- Author(s)
  Inoue, N., Watanabe, M., Katsumata, Y., Ishido, N., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Immunol Invest
  
  Volume: 47 Issue: 5 Pages: 534-542
- DOI
  10.1080/08820139.2018.1458861
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03261, KAKENHI-PROJECT-17H04111
[Journal Article] Methylation levels of the TNFA gene are different between Graves’ and Hashimoto’s diseases and influenced by the TNFA polymorphism2018
- Author(s)
  Morita Emi、Watanabe Mikio、Inoue Naoya、Hashimoto Hidemi、Haga Emi、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Autoimmunity
  
  Volume: 印刷中 Issue: 3 Pages: 118-125
- DOI
  10.1080/08916934.2018.1448078
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-16H03261
[Journal Article] Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease2018
- Author(s)
  Kunisato T, Watanabe M, Inoue N, Okada A, Nanba T, Kobayashi W, Inoue Y, Katsumata Y, Omori N, Nobuhara T, Takemura K, Hidaka Y, Iwatani Y
- Journal Title
  
  Autoimmunity
  
  Volume: 51 Issue: 7 Pages: 360-369
- DOI
  10.1080/08916934.2018.1534963
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-16H03261, KAKENHI-PROJECT-17H04111
[Journal Article] Association of the polymorphisms in Th2 chemotaxis-related genes with the development and prognosis of autoimmune thyroid diseases2018
- Author(s)
  Omori N, Watanabe M, Inoue N, Taniguchi J, Hidaka Y, Iwatani Y
- Journal Title
  
  Endocr J
  
  Volume: 65 Issue: 8 Pages: 815-826
- DOI
  10.1507/endocrj.EJ18-0050
- NAID
  130007458402
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08982, KAKENHI-PROJECT-17H04111
[Journal Article] Genotype-Based Epigenetic Differences in Monozygotic Twins Discordant for Positive Antithyroglobulin Autoantibodies2018
- Author(s)
  Watanabe Mikio、Takenaka Yoichi、Honda Chika、Osaka Twin Research Group、Iwatani Yoshinori
- Journal Title
  
  Thyroid
  
  Volume: 28 Issue: 1 Pages: 110-123
- DOI
  10.1089/thy.2017.0273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04111, KAKENHI-PROJECT-15K00402, KAKENHI-PROJECT-16H03261
[Journal Article] Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases.2017
- Author(s)
  Otsu, H., Watanabe, M., Inoue, N., Masutani, R., Iwatani, Y.
- Journal Title
  
  Clin Chem Lab Med
  
  Volume: 55 Issue: 5 Pages: 626-635
- DOI
  10.1515/cclm-2016-0449
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-16H03261, KAKENHI-PROJECT-17H04111
[Journal Article] Functional polymorphisms affecting Th1 differentiation are associated with the severity of autoimmune thyroid diseases2017
- Author(s)
  Inoue Naoya、Watanabe Mikio、Nakaguchi Azusa、Ueda Daishi、Kawaguti Hayaka、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 7 Pages: 695-703
- DOI
  10.1507/endocrj.EJ16-0551
- NAID
  130005866013
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04111
[Journal Article] Frequency-specific genetic influence on inferior parietal lobule activation commonly observed during action observation and execution2017
- Author(s)
  Araki Toshihiko、Onishi Mai、Yanagisawa Takufumi、Hirata Masayuki、Watanabe Yoshiyuki、Ogata Soshiro、Hayakawa Kazuo、Honda Chika、Watanabe Mikio、Iwatani Yoshinori、Yorifuji Shiro
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17660-17660
- DOI
  10.1038/s41598-017-17662-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K13271, KAKENHI-PROJECT-17H04111, KAKENHI-PUBLICLY-17H06032
[Journal Article] TSHR gene polymorphisms in the enhancer regions are most strongly associated with the development of Graves’ disease, especially intractable disease, and with that of Hashimoto’s disease.2017
- Author(s)
  Fujii, A., Inoue, N., Watanabe, M., Kawakami, C., Hidaka, Y., Hayashizaki, Y. and Iwatani, Y.
- Journal Title
  
  Thyroid
  
  Volume: 27 Issue: 1 Pages: 111-119
- DOI
  10.1089/thy.2016.0345
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-16H03261
[Journal Article] The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto’s disease.2017
- Author(s)
  Arakawa, Y. Watanabe, M., Takemura, K., Inoue, N., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  International Journal of Immunogenetics
  
  Volume: 44 Issue: 2 Pages: 41-50
- DOI
  10.1111/iji.12305
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-16K19207, KAKENHI-PROJECT-17H04111
[Journal Article] The polymorphisms in the thyroid peroxidase gene were associated with the development of autoimmune thyroid disease and the serum levels of anti-thyroid peroxidase antibody2017
- Author(s)
  Tomari Saki、Watanabe Mikio、Inoue Naoya、Mizuma Tomoyo、Yamanaka Chika、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 10 Pages: 1025-1032
- DOI
  10.1507/endocrj.EJ17-0191
- NAID
  130006186082
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04111
[Journal Article] Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease2017
- Author(s)
  Takuse Yukina、Watanabe Mikio、Inoue Naoya、Ozaki Ritsuko、Ohtsu Hiroshi、Saeki Minori、Katsumata Yuka、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Immunological Investigations
  
  Volume: 46 Issue: 6 Pages: 590-602
- DOI
  10.1080/08820139.2017.1322975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04111
[Journal Article] Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease2017
- Author(s)
  Mizuma Tomoyo、Watanabe Mikio、Inoue Naoya、Arakawa Yuya、Tomari Saki、Hidaka Yoh、Iwatani Yoshinori
- Journal Title
  
  Autoimmunity
  
  Volume: 50 Issue: 6 Pages: 386-392
- DOI
  10.1080/08916934.2017.1344971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04111
[Journal Article] Optimization of recovery and analysis of RNA in sorted cells in mRNA quantification after fluorescence-activated cell sorting.2016
- Author(s)
  Maeda, T., Date, A., Watanabe, M., Hidaka, Y., Iwatani, Y., Takano, T.
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 46 Pages: 435-441
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs.2016
- Author(s)
  Watanabe, M., Honda, C., The Osaka Twin Research Group, Iwatani, Y.
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 9 Issue: 1 Pages: 55-63
- DOI
  10.1186/s12920-016-0217-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-16H03261
[Journal Article] Association between functional SIRT1 polymorphisms and the clinical characteristics of patients with autoimmune thyroid disease.2016
- Author(s)
  Sarumaru M, Watanabe M, Inoue N, Hisamoto Y, Morita E, Arakawa Y, Hidaka Y, Iwatani Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 49
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] Association of the polymorphisms of chemokine genes (IL8, RANTES, MIG, IP10, MCP1 and IL16) with the pathogenesis of autoimmune thyroid diseases.2016
- Author(s)
  Akahane M, Watanabe M, Inoue N, Miyahara U, Arakawa Y, Inoue Y, Katsumata Y, Hidaka Y, Iwatani Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 49
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] Involvement of genes encoding apoptosis regulatory factors (FAS, FASL, TRAIL, BCL2, TNFR1 and TNFR2) in the pathogenesis of autoimmune thyroid diseases .2016
- Author(s)
  Inoue, N., Watanabe, M., Ishido, N., Kodu, A., Maruoka, H., Katsumata, Y., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Hum Immunol
  
  Volume: 77 Issue: 10 Pages: 944-945
- DOI
  10.1016/j.humimm.2016.07.232
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] Association of polymorphisms in the ICOS and ICOSL genes with the pathogenesis of autoimmune thyroid diseases2016
- Author(s)
 Yoshie N, Watanabe M, Inoue N, Kawaguchi H, Hidaka Y, Iwatani Y.
- Journal Title
 
 Endocr J
 
 Volume: 63 Issue: 1 Pages: 61-68
- DOI
 10.1507/endocrj.EJ15-0435
- NAID
 130005121495
- ISSN
 0918-8959, 1348-4540
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26293128
[Journal Article] Polymorphisms in and expression of Toll-like receptors in autoimmune thyroid diseases.2016
- Author(s)
  Inoue, N., Katsumata, Y., Watanabe, M., Ishido, N., Manabe, Y., Watanabe, A., Masutani, R., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 26 Issue: 3 Pages: 1-10
- DOI
  10.1080/08916934.2016.1261835
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-26860369, KAKENHI-PROJECT-17H04111
[Journal Article] Increases of microRNA let-7e in peripheral blood mononuclear cells in Hashimoto's disease.2016
- Author(s)
  Kagawa T, Watanabe M, Inoue N, Otsu H, Saeki M, Katsumata Y, Takuse Y, Iwatani Y.
- Journal Title
  
  Endocrine J
  
  Volume: 63
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases .2016
- Author(s)
  Saeki, M., Watanabe, M., Inoue, N., Tokiyoshi, E. Takuse, Y., Arakawa, Y. Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 49 Pages: 514-522
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] Association between functional polymorphisms in the Toll-like receptor 4 (TLR4) gene and HD severity.2015
- Author(s)
  Inoue, N., Watanabe, M., Katsumata, Y., Ishido, N., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Tissue Antigens
  
  Volume: 85 Issue: 3 Pages: 209-211
- DOI
  10.1111/tan.12518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590695, KAKENHI-PROJECT-26293128, KAKENHI-PROJECT-26860369
[Journal Article] The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits2015
- Author(s)
  Karri Silventoinen, Aline Jelenkovic, Reijo Sund, et al.
- Journal Title
  
  Twin Research and Human Genetics
  
  Volume: 18(4) Issue: 4 Pages: 348-360
- DOI
  10.1017/thg.2015.29
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23593419, KAKENHI-PROJECT-26671010, KAKENHI-PROJECT-15H05105, KAKENHI-PROJECT-26293128
[Journal Article] The Relationship between Skewed X Chromosome Inactivation and the Prognosis of Graves’ and Hashimoto’s Diseases2015
- Author(s)
  Ishido,N., Inoue, N., Watanabe, M., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Thyroid
  
  Volume: 25 Issue: 2 Pages: 256-261
- DOI
  10.1089/thy.2014.0318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590695, KAKENHI-PROJECT-26293128
[Journal Article] Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.2015
- Author(s)
  Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Chika Honda et al.
- Journal Title
  
  Twin Research and Human Genetics
  
  Volume: 18 Issue: 5 Pages: 557-570
- DOI
  10.1017/thg.2015.57
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26671010, KAKENHI-PROJECT-15H05105, KAKENHI-PROJECT-25671015, KAKENHI-PROJECT-26293128
[Journal Article] Associations of single nucleotide polymorphisms in pri-miR-125a and the expression of mature miR-125a with the development and prognosis of autoimmune thyroid diseases.2014
- Author(s)
  Inoue, Y., Watanabe, M., Inoue, N., Kagawa, T., Shibutani, S., Otsu, H., Saeki, M., Takuse, Y., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 178 Issue: 2 Pages: 229-235
- DOI
  10.1111/cei.12410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590695, KAKENHI-PROJECT-26293128
[Journal Article] In vitro evaluations of topical agents to treat Acanthamoeba keratitis.2014
- Author(s)
  Sunada A, Kimura K, Nishi I, Toyokawa M, Ueda A, Sakata T, Suzuki T, Inoue Y, Ohashi Y, Asari S,Iwatani Y.
- Journal Title
  
  Ophthalmology
  
  Volume: 121 Issue: 10 Pages: 2059-2065
- DOI
  10.1016/j.ophtha.2014.04.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293128
[Journal Article] The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases.2014
- Author(s)
  Inoue, N., Watanabe, M., Ishido, N., Katsumata, Y., Kagawa, T., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 178 Issue: 2 Pages: 262-269
- DOI
  10.1111/cei.12420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590695, KAKENHI-PROJECT-26293128
[Journal Article] Interference by Pralidoxime (PAM) salts in clinical laboratory tests2013
- Author(s)
  Nagase, S., Kohguchi, K., Tohyama, K., Watanabe, M., Iwatani, Y
- Journal Title
  
  Clin Chim Acta
  
  Volume: 416 Pages: 72-79
- DOI
  10.1016/j.cca.2012.11.017
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Preparation of thyroid follicular cells for mRNA quantifi cation after fl uorescence-activated cell sorting2013
- Author(s)
  Matsumoto, C., Ito, M., Yamada, H., Yoshida, H., Watanabe, M., Hidaka, Y., Iwatani, Y., Miyauchi, A., Takano, T
- Journal Title
  
  Scandinavian Journal of Clinical & Laboratory Investigation
  
  Volume: 73 Issue: 3 Pages: 245-252
- DOI
  10.3109/00365513.2013.769624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590670, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease2013
- Author(s)
  Inoue, N., Watanabe, M., Wada, M., Morita, M., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Cytokine
  
  Volume: 64 Issue: 1 Pages: 370-374
- DOI
  10.1016/j.cyto.2013.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] The association between a functional polymorphism in the CD24 gene and the development of autoimmune thyroid diseases2013
- Author(s)
  Inoue, N., Watanabe, M., Hayashi F., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Tissue Antigen
  
  Volume: 81(3) Issue: 3 Pages: 161-3
- DOI
  10.1111/tan.12070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] Different genotypes of a functional polymorphism of the TSHR gene are associated with the development and severity of Graves and Hashimotos diseases2013
- Author(s)
  Inoue, N., Watanabe, M., Katsumata, Y., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Tissue Antigen
  
  Volume: 82 Issue: 4 Pages: 288-290
- DOI
  10.1111/tan.12190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] Genes that characterize T3-predominant Graves' thyroid tissues2013
- Author(s)
  Matsumoto, C., Ito, M., Yamada, H., Yamakawa, N., Yoshida, H., Date, A., Watanabe, M., Hidaka, Y., Iwatani, Y., Miyauchi, A., Takano, T
- Journal Title
  
  Eur J Endocrinol
  
  Volume: 168(2) Issue: 2 Pages: 137-44
- DOI
  10.1530/eje-12-0507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590670, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] An Overview of multidisciplinary Research Resouces at the Osaka University Center for Twin Research2013
- Author(s)
  Kazuo Hayakawa, Yoshinori Iwatani and the Osaka Twin Research Group
- Journal Title
  
  Twin Research and Human Genetics
  
  Volume: 16(1) Issue: 1 Pages: 217-220
- DOI
  10.1017/thg.2012.141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659428, KAKENHI-PROJECT-23390150
[Journal Article] The GG genotype of the 1125G/T polymorphism in the EPO gene protects against the development of Graves' disease2013
- Author(s)
  Inoue, N. Watanabe, M., Nobuhara, T., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Immunol Letters
  
  Volume: 156 Issue: 1-2 Pages: 156-158
- DOI
  10.1016/j.imlet.2013.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] Prolonged hybridization with a cRNA probe improves the signal to noise ratio for in-tube in situ hybridization for quantification of mRNA after fluorescence-activated cell sorting2012
- Author(s)
  Yamada, H., Yamakawa, N., Watanabe, M., Hidaka, Y., Iwatani, Y., Takano, T.
- Journal Title
  
  Biotech Histochem
  
  Volume: (in press) Issue: 5 Pages: 366-71
- DOI
  10.3109/10520295.2012.672650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590625, KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590670, KAKENHI-PROJECT-23590671
[Journal Article] Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in Genome-wide association studies2012
- Author(s)
  Inoue, N. Watanabe, M., Yamada, H., Takemura, K., Hayashi, F., Yamakawa, N., Akahane, M., Shimizuishi, Y., Hidaka, Y., Iwatani, Y
- Journal Title
  
  J Clin Immunol
  
  Volume: 32 Issue: 6 Pages: 1243-52
- DOI
  10.1007/s10875-012-9721-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: The first clinical trial in 130 cases2012
- Author(s)
 Yamada, H., Takano, T., Kihara, M., Hirokawa, M., Yoshida, H., Watanabe, M., Iwatani, Y., Hidaka, Y., Miyauchi, A
- Journal Title
 
 Endocr J
 
 Volume: 59 Issue: 7 Pages: 621-630
- DOI
 10.1507/endocrj.EJ12-0077
- NAID
 130004443816
- ISSN
 0918-8959, 1348-4540
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23390150
[Journal Article] Preparation of a cut-off solution that gives a clear index for distinguishing Le(a-b-) sera in CA19-9 assays using SphereLight 180 and Architect i2000 kits2012
- Author(s)
  Hanada, H., Mugii, S., Takeoka, K., Maeda, I., Watanabe, M., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Clinica Chemica Acta
  
  Volume: 413(1-2) Pages: 278-281
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Association ofpolymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR, and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease2012
- Author(s)
  Arakawa, Y., Watanabe, M., Inoue, N., Sarumaru, M., Hidaka, Y., Iwatani, Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 170(2) Issue: 2 Pages: 194-201
- DOI
  10.1111/j.1365-2249.2012.04646.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] mRNA quantification after fluorescence activated cell sorting using locked nucleic acid probes2011
- Author(s)
  Maruo, R., Yamada, H., Watanabe, M., Hidaka, Y., Iwatani, Y. Takano, T
- Journal Title
  
  Mol Biotechnol
  
  Volume: 49(1) Pages: 42-47
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Transcriptional activity of the 5'-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines2011
- Author(s)
  Yamada, H., Takano, T., Matsuzuka, F., Watanabe, M., Miyauchi, A., Iwatani, Y
- Journal Title
  
  Genet Mol Biol
  
  Volume: 34(1) Pages: 6-10
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease2011
- Author(s)
  Morita, M., Watanabe, M., Inoue, N., Inaoka, C., Akamizu, T., Tatsumi, K., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Autoimmunity
  
  Volume: 45(2) Issue: 2 Pages: 129-36
- DOI
  10.3109/08916934.2011.622013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590625, KAKENHI-PROJECT-23390150, KAKENHI-PROJECT-23590671, KAKENHI-PROJECT-24590695
[Journal Article] Evaluation of amphotericin B and micafungin combination against clinical isolates of Aspergillus species2011
- Author(s)
  Nishi, I., Sunada, A., Toyokawa, M., Asari, S., Iwatani, Y
- Journal Title
  
  J Chemother
  
  Volume: 23(2) Pages: 102-6
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Association of functional GITR gene polymorphisms related to expression of GITR molecules with prognosis of autoimmune thyroid disease2011
- Author(s)
  Tomizawa, R., Watanabe, M., Inoue N., Takemura, K., Hidaka, Y., Akamizu, T., Hayakawa, K., Iwatani, Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 165(2) Pages: 141-147
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Association of functional polymorphisms in promoter regions of IL5, IL6 and IL13 genes with development and prognosis of autoimmune thyroid diseases.2011
- Author(s)
  Inoue N, Watanabe M, Morita M, Tatusmi K, Hidaka Y, Akamizu T, Iwatani Y.
- Journal Title
  
  Clin Exp Immunol. 163(3)
  
  Pages: 318-323
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Association of functional polymorphisms in promoter regions of IL5, IL6, and IL13 genes with development and prognosis of autoimmune thyroid diseases2011
- Author(s)
  Inoue, N., Watanabe, M., Morita, M., Tatsumi, K., Hidaka, Y., Akamizu, T., Iwatani, Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 163(3) Pages: 318-323
- Data Source
  KAKENHI-PROJECT-23390150
[Journal Article] Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases.2010
- Author(s)
  Inoue, N., Watanabe, M., Morita, M., Tomizawa, R., Akamizu, T., Tatsumi, K., Hidaka, Y., Iwatani, Y.
- Journal Title
  
  Clin Exp Immunol 162(3)
  
  Pages: 402-406
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease.2009
- Author(s)
  Nanba, T., Watanabe, M., Inoue, N., Iwatani, Y.
- Journal Title
  
  Thyroid 19(5)
  
  Pages: 495-501
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Association of -31C/T functional polymorphism in the interleukin-1beta gene with the intractability of Graves' disease and the proportion of Th17 cells.2009
- Author(s)
  Hayashi, F., Watanabe, M., Nanba, T., Inoue, N., Akamizu, T., Iwatani, Y.
- Journal Title
  
  Clin Exp Immunol 158(3)
  
  Pages: 281-286
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-TSH receptor antibody.2009
- Author(s)
  Inoue, N., Watanabe, M., Nanba, T., Wada, M., Akamizu, T., Iwatani, Y.
- Journal Title
  
  Clin Exp Immunol 156(2)
  
  Pages: 199-204
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] The-590CC Genotype in the IL4 Gene as a Strong Predictive Factor for the Development of Hypothyroidism in Hashimoto Disease.2008
- Author(s)
  Nanba T, Watanabe M, Akamizu T, Iwatani Y
- Journal Title
  
  Clin Chem 54(3)
  
  Pages: 621-623
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] The 869T/C polymorphism in the transforming growth factor-beta1 gene is associated with the severity and intractability of autoimmune thyroid disease.2008
- Author(s)
  Yamada H, Watanabe M, Nanba T, Akamizu T, Iwatani Y
- Journal Title
  
  Clin Exp Immunol 151
  
  Pages: 379-382
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Decrease of intrathyroidal CD161+ Valpha24+Vbeta11+ NKT cells in Graves' disease.2008
- Author(s)
  Watanabe M, Nakamura Y, Matsuzuka F, Takamura Y, Miyauchi A, Iwatani Y
- Journal Title
  
  Endocrine J 55
  
  Pages: 199-203
- Data Source
  KAKENHI-PROJECT-20390168
[Journal Article] Apoptosis-induced decrease of intrathyroidal CD4+CD25+ regulatory T cells in autoimmune thyroid diseases.2007
- Author(s)
  Nakano A, Watanabe M, Iida T, Kuroda S, Matsuzuka F, Miyauchi A, Iwatani Y
- Journal Title
  
  Thyroid 17
  
  Pages: 25-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Association between the severity of Hashimoto' s disease and the functional +874A/T polymorphism in the interferon-γ gene.2006
- Author(s)
  Ito C, Watanabe M, Okuda N, Watanabe C Iwatani y
- Journal Title
  
  Endocrine J 53
  
  Pages: 473-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Urine flow cytometer quantification of leukocytes in samples containing a large proportion o lymphocytes.2006
- Author(s)
  Yamanishi H, Imai N, Ohmine T, Nishiyama M, Suehisa E, Kanakura Y, Iwatani Y
- Journal Title
  
  Clin Biochem 39
  
  Pages: 857-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus.2006
- Author(s)
  Nojima J, Iwatani Y, Suehisa E, Kuratsune H, Kanakura Y
- Journal Title
  
  Thrombosis 91
  
  Pages: 699-702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Insufficient filling of vacuum tubes as a cause of microhemolysis and elevated serum lactate dehydrogenase levels. Use of a data-mining technique in evaluation of questionable laboratory test results.2006
- Author(s)
  Tamechika M, Iwatani Y, Tohyama K, Ichihara K
- Journal Title
  
  Clin Chem Lab Med 44
  
  Pages: 657-661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Penicillin susceptibility o non-serotypeable Streptococcus pneumoniae from ophthalmic specimens.2006
- Author(s)
  Kojima F, Nakagami Y, Takemori K, Iwatani Y, Fujimoto S
- Journal Title
  
  J Antimicrob Chemother 12
  
  Pages: 199-202
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease.2005
- Author(s)
  Hiratani H, Bowden DW, Ikegami S, Shirasawa S, Shimizu A, Iwatani Y, Akamizu T
- Journal Title
  
  J Clin Endocrinol Metab 90
  
  Pages: 2898-903
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Inflammation and liver dysfunction.2005
- Author(s)
  Kabutomori O, Kanakura Y, Iwatani Y
- Journal Title
  
  Ann Hematol 84
  
  Pages: 136-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] A useful new classification of dysmorphic urinary erythrocytes.2005
- Author(s)
  Nagahama D, Yoshiko K, Watanabe M, Morita Y, Iwatani Y, Matsuo S
- Journal Title
  
  Clin Exp Nephrol 9
  
  Pages: 304-9
- NAID
  10016913860
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Acquired activated protein C resistance associated with IgG antibodies against beta2-glycoprotein I and prothrombin as a strong risk factor for venous thromboembolism.2005
- Author(s)
  Nojima J, Kuratsune H, Suehisa E, Iwatani Y, Kanakura Y
- Journal Title
  
  Clin Chem 51
  
  Pages: 545-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390164
[Journal Article] Association of functional GITR gene polymorphisms related to expression of GITR molecules with prognosis of autoimmune thyroid disease.
- Author(s)
  Tomizawa R, Watanabe M, Inoue N, Takemura N, Hidaka Y, Akamizu T, Hayakawa K, Iwatani Y.
- Journal Title
  
  Clin.Exp.Immunolo. in press
- Data Source
  KAKENHI-PROJECT-20390168
[Presentation] (Discussed Poster) Association of functional polymorphisms related to the transcriptional level of FOXP3 gene with prognosis of autoimmune thyroid diseases.2010
- Author(s)
  Watanabe, M., Inoue, N., Morita, M., Tomizawa, R., Akamizu, T., Tatsumi, K., Hidaka, Y., Iwatani, Y.
- Organizer
  14th International Thyroid Congress (ITC)
- Place of Presentation
  Paris
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-20390168
[Presentation] Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease.2010
- Author(s)
  Watanabe, M., Nanba, T., Inoue, N., Iwatani, Y.
- Organizer
  14th International Congress of Endocrinology (ICE)
- Place of Presentation
  Kyoto
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20390168
[Presentation] Association of the -31C/T functional polymorphism in the interleukin-1β gene with the intractability of Graves' disease and the proportion of Th17 cells.2009
- Author(s)
  Watanabe, M., Hayashi, F., Nanba, T., Inoue, N., Akamizu, T., Iwatani, Y.
- Organizer
  80th Annual Meeting of the American Thyroid Association
- Place of Presentation
  Palm Beach
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20390168
[Presentation] Involvement of the functional polymorphisms in TNFA gene in the pathogenesis of autoimmune thyroid diseases and the production of anti-TSH receptor antibody.2009
- Author(s)
  Inoue, N., Watanabe, M., Nanba, T., Akamizu, T., Iwatani, Y.
- Organizer
  9th Congress of the Asia and Oceania Thyroid Association (AOTA)
- Place of Presentation
  Nagoya
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-20390168
[Presentation] Patients of Hashimoto's disease with-590CC genotype in the IL4 gene would develop hypothyroidism.2008
- Author(s)
  Watanabe M, Namba T, Akamizu T, Iwatani Y
- Organizer
  The 79th Annual Meeting of the American Thyroid Association
- Place of Presentation
  Chicago, IL
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20390168

1. WATANABE Mikio (50294088)

# of Collaborated Projects: 4 results

# of Collaborated Products: 53 results
2. HIDAKA Yoh (30243231)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
3. AMINO Nobuyuki (60028694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 玉置治夫 (20221400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAGORO Aya (60273653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KASHIWAI Taku (00252685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TADA Hisato (80263242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORI Hidemitsu (00182204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANIZAWA Osamu (30028443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高田薫 (80216655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 光田信明 (50209805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小杉厚 (90186685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUZUKI Hajime

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 館純子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 青笹美恵子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森英光

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. AOZASA Mieko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIRATA masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. WATANABE yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 荒木俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 本多智佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 早川和生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWATANI Yoshinori 岩谷 良則

岩谷 良則 イワタニ ヨシノリ

Research Projects

Research Products

Co-Researchers

Development of the diagnostic methods to predict the development and the prognosis of autoimmune diseases based on the genome and epigenome informationsPrincipal Investigator

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Diagnostic methods to predict the development and the prognosis of autoimmune diseases based on the reguratory mechanisms for gene expressionPrincipal Investigator

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Diagnostic methods to predict the development of autoimmune diseases by gene polymorphisms of immune regulatory factorsPrincipal Investigator

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Development of predictive diagnostic method for autoimmune diseases on the basis of the mechanism of peripheral self-tolerance inductionPrincipal Investigator

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Development of predictive diagnostic method for autoimmune disease by gene polymorphisms of immunomodulatory factorsPrincipal Investigator

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Development of the method to diagnose the prognosis of autoimmune disease by clarifying the pathologic factors.Principal Investigator

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Development of a sensitive analyzer for multiple immune function.Principal Investigator

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Study on abnormalities of peripheral tolerance induction by target cells in organ-specific autoimmune diseases.Principal Investigator

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Prediction of postpartum onset of autoimmune disease and its prevention

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Study on lymphocyte subsets infiltrating the target organ in autoimmune diseases.Principal Investigator

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合成オリゴペプチドを用いたTSH受容体抗体の免疫測定法の開発と臨床応用

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Development of an automatic high-sensitive assay system for cells producing a specific antibody or a cytokine.Principal Investigator

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Study on B cell subsets producing ongan-specific autoantibodiesPrincipal Investigator

Principal Investigator

Project Period (FY)

IWATANI Yoshinori 岩谷良則

岩谷良則イワタニヨシノリ