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UBUKATA Makoto  生方 信

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… Alternative Names

生方 信  ウブカタ マコト

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Researcher Number 60168739
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2016: 北海道大学, 農学研究院, 特任教授
2012 – 2015: 北海道大学, (連合)農学研究科(研究院), 教授
2014: 北海道大学, 大学院農学研究院, 教授
2007 – 2009: Hokkaido University, 大学院・農学研究院, 教授
2006: 北海道大学, 大学院農学研究院, 教授 … More
2003 – 2005: 北海道大学, 大学院・農学研究科, 教授
1996 – 2001: 富山県立大学, 工学部, 教授
1992 – 1993: 理化学研究所, 抗生物質研究室, 副主任研究員
1986: 理化学研究所, 抗生物質研究室, 研究員 Less
Review Section/Research Field
Principal Investigator
Bioproduction chemistry/Bioorganic chemistry / Science and Engineering / Bioproduction chemistry/Bioorganic chemistry / 製造化学・食品 / Bioorganic chemistry
Except Principal Investigator
Wood science / Applied microbiology / 製造化学・食品
Keywords
Principal Investigator
HDAC / 3T3-L1細胞 / PPARγ / ミコフェノール酸 / 絶対配置 / トウトマイシン / PPARα / NF-κB / 阻害剤 / PCR … More / tautomycin / NGF / indocarbazostatin / inhibitor / エピデルスタチン / X線結晶解析 / 分子力場計算 / NOE / 分子内アミドセレニル化 / プロテインホスファターゼ / 立体配座 / ブレッブ形成 / 3T3-F442細胞 / 治療薬シーズ / 分化誘導調節活性 / アガリスク / IMPデヒドロゲナーゼ / 分化誘導促進 / 6-tuliposide B / Baylis-Hillman反応 / PP1 / TNFα / IKK / RPS3a / トウトマイセチン / 1型ホスファターゼ / リン酸化 / ATM / MF-κB / オートファジー / エポジムノラクタム / 全合成 / 構造活性相関 / セルレニン / 構造ー活性相関 / タンデム型不斉エポキシ化 / ポリケチド / クローニング / 形質転換 / 遺伝子破壊 / 生合成遺伝子 / 放線菌 / cloning / polyketide / gene disruption / インドカルバゾスタチン / PC12細胞 / 神経突起伸展 / K252a / PKC / PC12 cells / neurite outgrowth / 脂肪細胞分化誘導 / プロシアニジン / 分化誘導阻害 / プロアントシアニジン / セスキテルペノイド化合物 / 3T3-L1 cells / cell differentiation / mycophenolic acid / procyanidin … More
Except Principal Investigator
構造決定 / lignin / muconate / anaerobic culture / muconic acid / ムコン酸類 / 嫌気的 / 生分解 / ムコン酸 / リグニン / 嫌気条件 / 難培養性微生物 / 生育因子 / 真正細菌 / 単離 / ポルフィリン / 細菌細胞壁 / ペプチドグリカン / リピドサイクル / リポシドマイシン Less
  • Research Projects

    (12 results)
  • Research Products

    (84 results)
  • Co-Researchers

    (5 People)
  •  Structure and function of the novel autophagy inducer, (+)-epogymnolactamPrincipal Investigator

    • Principal Investigator
      Ubukata Makoto
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Hokkaido University
  •  Sphingomonas sp.の生産する異種微生物生育因子の単離・構造決定

    • Principal Investigator
      三橋 進也
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      Hokkaido University
  •  The evaluation of anaerobic muconates metabolism and ethanol fermentation

    • Principal Investigator
      SHIGETOMI Kengo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Wood science
    • Research Institution
      Hokkaido University
  •  Focused proteomics of phosphorylated proteins using tautomycetin and its applicationPrincipal Investigator

    • Principal Investigator
      UBUKATA Makoto
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Hokkaido University
  •  天然有機化合物を基軸とした難治疾患治療薬シーズのデザインと活性評価Principal Investigator

    • Principal Investigator
      生方 信
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  天然有機化合物を基軸とした難治性疾患治療薬シーズのデザインと活性評価Principal Investigator

    • Principal Investigator
      生方 信
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  Exploratory research on modulators of adipocyte differentiationPrincipal Investigator

    • Principal Investigator
      UBUKATA Makoto
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Hokkaido University
  •  Structures and biological activities of indocarbazostain, new inhibitors of NGF-induced neurite outgrowth in PC12 cells.Principal Investigator

    • Principal Investigator
      UBUKATA Makoto
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Toyama Prefectural University
  •  Cloning and Analysis of Tautomycin Biosynthetic GenesPrincipal Investigator

    • Principal Investigator
      UBUKATA Makoto
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Toyama Prefectural University
  •  Tautomycin及び類縁体の構造と機能に関する研究Principal Investigator

    • Principal Investigator
      生方 信
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Epiderstatinの合成研究Principal Investigator

    • Principal Investigator
      生方 信
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      製造化学・食品
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細菌細胞壁リピドサイクル制御物質,リポシドマイシンの化学と作用

    • Principal Investigator
      磯野 清
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      製造化学・食品
    • Research Institution
      The Institute of Physical and Chemical Research

All 2017 2016 2015 2014 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] 顕著な活性を有する生理活性物質の発見とその化学生物学的展開 平成29年度 日本農学賞受賞論文要旨2017

    • Author(s)
      生方 信
    • Total Pages
      5
    • Publisher
      日本農学会
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Book] 基礎化学編 第4章 イオン化合物第2版マクマリー生物有機化学菅原二三男監訳2007

    • Author(s)
      生方 信(分担翻訳執筆)
    • Total Pages
      29
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Book] "基礎化学編 第4章 イオン化合物" 第2版マクマリー生物有機化学菅原二三男監訳2007

    • Author(s)
      生方信(分担翻訳執筆)
    • Total Pages
      29
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Quercetin inhibits advanced glycation end product formation via chelating metal ions, trapping methylglyoxal, and trapping reactive oxygen species.2017

    • Author(s)
      M.N.I. Buiyan, S. Mitsuhashi, K. Shigetomi, and M. Ubukata
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 81 Pages: 882-890

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] Growth mechanism of uncultured actinobacterial strain Leucobacter sp. ASN212 by zinc coproporphyrin.2017

    • Author(s)
      R. Takai, K. Shigetomi, Y. Kamagata, and M. Ubukata
    • Journal Title

      Heterocycles

      Volume: 95 Pages: 145-151

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] Zincmethylphyrins and coproporphyrins, novel growth factors released by Sphingopyxis sp., enable laboratory cultivation of previously uncultured Leucobacter sp. through interspecies mutualism.2016

    • Author(s)
      M.N.I. Bhuiyan, R. Takai, S. Mitsuhashi, K. Shigetomi, Y. Tanaka, Y. Kamagata, and M. Ubukata
    • Journal Title

      The Journal of Antibiotics

      Volume: 69 Pages: 97-103

    • NAID

      120005749616

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] Mycophenolic acid and its derivative as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense.2016

    • Author(s)
      K. Suganuma, A.E. Sarwono, S. Mitsuhashi, M. Jxkalski, T. Okada, M. Nthatisi, J. Yamagishi, M. Ubukata, and N. Inoue
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: 60 Pages: 4391-4393

    • NAID

      120006390948

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] Guideline for the use and interpretation of assays for monitoring autophagy (3rd edition)2016

    • Author(s)
      D.J.Klionsky and M. Ubukata et al.
    • Journal Title

      Autophagy

      Volume: 12 Pages: 1-222

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] (+)-Epogymnolactam, a novel autophagy iducer from mycerial culture of Gymnopus sp.2015

    • Author(s)
      S. Mitsuhashi, C. Shindo, K. Shigetomi, T. Miyamoto, and M. Ubukata
    • Journal Title

      Phytochemistry

      Volume: 114 Pages: 155-159

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] First total synthesis of (+)-epogymnolactam, a novel autophagy inducer2015

    • Author(s)
      Y. Okado, K. Shigetomi, S. Mitsuhashi, and M. Ubukata
    • Journal Title

      The Journal of Antibiotics

      Volume: 68 Pages: 721-724

    • NAID

      120005768785

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] (+)-Epogymnolactam, a novel autophagy inducer from mycelial culture of Gymnopus sp.2014

    • Author(s)
      S. Mitsuhashi, C. Shindo, K. Shigetomi, T. Miyamoto, and M. Ubukata
    • Journal Title

      Phytochemistry

      Volume: なし

    • DOI

      10.1016/j.phytochem.2014.08.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Journal Article] The antibacterial properties of 6-tuliposide B. synthesis of 6-tuliposide B analogues and structure-activity relationship2010

    • Author(s)
      K. Shigetomi, M. Ubukata, 他2名 (4番目)
    • Journal Title

      Phtochemistry 71

      Pages: 312-324

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Purification and characterization of tuliposide-converting enzyme from the bulbs of Tulipa generiana2009

    • Author(s)
      Y. Kato, M. Ubukata, 他5名 (3番目)
    • Journal Title

      Biosci. Biotechnol. Biochem. 73

      Pages: 1895-1897

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Pyrogallol structure in polyphenol is involved in apoptoshis-induction on HEK293T and K562 cells2008

    • Author(s)
      S. Mitsuhashi, M. Ubukata, 他3名 (5番目)
    • Journal Title

      Molecules 13

      Pages: 2998-3006

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase in cellular level2008

    • Author(s)
      D. I. Batovska, M. Ubukata, 他4名 (6番目)
    • Journal Title

      Biosci. Biotechnol. Biochem. 72

      Pages: 2623-2631

    • NAID

      10027533020

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] First total synthesis of tuliposide B2008

    • Author(s)
      K. Shigetomi, M. Ubukata, 他2名 (4番目)
    • Journal Title

      Tetrahedron Asymmetry 19

      Pages: 1444-1449

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Tautomycetin suppresses the TNFalpha/NF-kappaB pathway via inhibition of IKK activation2008

    • Author(s)
      S. Mitsuhashi, M. Ubukata, 他5名 (7番目)
    • Journal Title

      Int. J. Oncol. 33

      Pages: 1027-1035

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Low molecular lignin suppresses activation of NF-κB and HIV-1 promoter2007

    • Author(s)
      S. Mitsuhashi, M. Ubukata, 他3名 (5番目)
    • Journal Title

      Bioorg. Med. Chem. 16

      Pages: 2645-2650

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Mycophenolic acid as a latent agonist of PPARγ2007

    • Author(s)
      M. Ubukata, 他9名 (1番目)
    • Journal Title

      Bioorg. Med. Chem. Lett. 17

      Pages: 4746-4770

    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Mycophenolic acid as a latent agonist of PPARγ2007

    • Author(s)
      M. Ubukata, et al.
    • Journal Title

      BioOrganic & Medicinal Chemistry Letters 17

      Pages: 4746-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Journal Article] Mycophenolic acid as a latent agonist of PPARγ2007

    • Author(s)
      M. Ubukata, et. al.
    • Journal Title

      BioOrganic & Medicinal Chemistry Letters 17

      Pages: 4746-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Journal Article] Chemical synthesis of β-O-4 type artificial lignin2006

    • Author(s)
      T.Kishimoto, Y.Uraki, M.Ubukata
    • Journal Title

      Organic and Biomolecular Chemistry 4

      Pages: 1343-1347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Biosynthesis of indocarbazostatin B, incorporation of D-[U^<-13>C] glucose and L-[2^<-13>C]tryptophan2005

    • Author(s)
      Y.Feng, M.Mitsuhashi, T.Kishimoto, M.Ubukata
    • Journal Title

      J.Antibiotics 58

      Pages: 759-765

    • NAID

      10016905389

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Synthetic studies of liposidomycin degradation product : Attempt for introduction of an uracil group2005

    • Author(s)
      S.Fukunishi, M.Ubukata, N.Nakajima
    • Journal Title

      Heterocycles 66

      Pages: 129-134

    • NAID

      40007080605

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Synthesis of some phenylpropanoid monoglycerides via the Mitsunobu protocol2005

    • Author(s)
      D.I.Batovska, T.Kishimoto, V.S.Bankova, Z.G.Kamenarska, M.Ubukata
    • Journal Title

      Molecules 10

      Pages: 552-558

    • NAID

      120000953695

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Protein phosphatase type 2A, PP2A is involved in degradation of gp1302005

    • Author(s)
      S.Mitsuhashi, H.Shima, N.Tanuma, S.Sasa, K.Onoe, M.Ubukata, K.Kikuchi
    • Journal Title

      Molecular and Cellular Biochemistry 269

      Pages: 183-187

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Anther- specific production of antimicrobial tuliposide B in tulips2005

    • Author(s)
      K.Shoji, M.Ubukata, K.Momonoi, T.Tsuji, T.Morimatsu
    • Journal Title

      J.Japan.Soc.Hort.Sci. 74

      Pages: 469-475

    • NAID

      110002322370

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Inhibition of preadipocyte differentiation by germacranolides from Calea urticifolia in 3T3-L1 cells2005

    • Author(s)
      N.Matsuura, M.Yamada, H.Suzuki, N.Hasegawa, C.Kurosaka, M.Ubukata, T.Tanaka, M.Iinuma
    • Journal Title

      Biosci.Biotechnol.Biochem. 69

      Pages: 2470-2474

    • NAID

      130000030470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Easy synthesis of β-O-4 type lignin related polymer2005

    • Author(s)
      T.Kishimoto, Y.Uraki, M.Ubukata
    • Journal Title

      Organic and Biomolecular Chemistry 3

      Pages: 1067-1073

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Lipase-mediated desymmetrisation of glycerol with aromatic and aliphatic anhydrides2004

    • Author(s)
      D.I.Batovska, S.Tsubota, Y.Kato, Y.Asano, M.Ubukata
    • Journal Title

      Tetrahedron : Asymmetry 15

      Pages: 3551-3559

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Delignification mechanism during high-boiling solvent pulping. Part 6 : Changes in lignin structure analyzed by ^1H^<-13>C correlation 2-D NMR spectroscopy2004

    • Author(s)
      T.Kishimoto, A.Ueki, H.Takamori, M.Ubukata
    • Journal Title

      Holzforschung 58

      Pages: 355-362

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Highly stereoselective synthesis and inhibitory activity of Maillard reaction of 3,4-trans catechin and epicatechin dimer, procyanidin B1, B2, B3, B4 and their acetates.2004

    • Author(s)
      A.Saito, N.Nakajima, N.Matsuura, A.Tanaka, M.Ubukata
    • Journal Title

      Heterocycles 62

      Pages: 479-489

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Efficient stereoselective synthesis of proanthocyanidin trimers with TMSOTf-catalyzed intermolecular condensation.2004

    • Author(s)
      A.Saito, A.Tanaka, M.Ubukata, N.Nakajima
    • Journal Title

      Synlett

      Pages: 1069-1072

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Systematic synthesis of four epicatechin series procyanidin trimers and their inhibitory activity on the Maillard reaction and antioxidant activity2004

    • Author(s)
      A.Saito, Y.Doi, A.Tanaka, N.Matsuura, M.Ubukata, N.Nakajima
    • Journal Title

      BioOrg.Med.Chem. 12

      Pages: 4783-4790

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Germacranolides from Calea urticifolia.2004

    • Author(s)
      M.Yamada, N.Matsuura, H.Suzuki, C.Kurosaka, N.Hasegawa, M.Ubukata, T.Tanaka, M.Iinuma
    • Journal Title

      Phytochemistry 65

      Pages: 3107-3111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Design and synthesis of 16-membered hybrid macrolide having a thiazole side chain on the carbonolide skeleton2004

    • Author(s)
      N.Nakajima, M.Ubukata
    • Journal Title

      Heterocycles 64

      Pages: 333-345

    • NAID

      40006603423

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Indocarbazostatins C and D, New inhibitors of NGF-induced neuronal differentiation in PC12 cells2004

    • Author(s)
      Y.Feng, N.Matsuura, M.Ubukata
    • Journal Title

      J.Antibiotics 57

      Pages: 627-633

    • NAID

      10013726815

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Body temperature-responsive gels derived from hydroxypropylcellulose bearing lignin.2004

    • Author(s)
      Y.Uraki, T.Imura, T.Kishimoto, M.Ubukata
    • Journal Title

      Carbohydr.Polym. 58

      Pages: 123-130

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Stereoselection of 3,4-cis and 3,4-trans catechin and catechin condensation under intermolecular coupling method.2004

    • Author(s)
      A.Saito, A.Tanaka, M.Ubukata, N.Nakajima
    • Journal Title

      Synlett

      Pages: 2040-2042

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] N-acetylglycine side chain is critical for the antimicrobial activity of xanthostatin2003

    • Author(s)
      S.-K.Kim.M.Ubukata, K.Isono
    • Journal Title

      Journal of Microbiology and Biotechnology 13

      Pages: 998-1000

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Synthesis and activity of pyrimidinylpropenamide antibiotics : The alkyl analogues of sparsomycin.2003

    • Author(s)
      N.Nakajima, T.Enomoto, T.Watanabe, N.Matsuura, M.Ubukata
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry 67

      Pages: 2556-2566

    • NAID

      110002694020

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Toward the assignment of liposidomycin stereochemistry : Synthesis of 1,4-diazepan-3-one analogues by reductive amination approach.2003

    • Author(s)
      N.Nakajima, T.Isobe, S.Irisa, M.Ubukata
    • Journal Title

      Heterocycles 59

      Pages: 107-113

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Six flavono stilbenes from Gnetum africanum and Gnetum gnemon.2003

    • Author(s)
      I.Iliya, T.Tanaka, Z.Ali, M.Iinuma, M.Furusawa, K.Nakaya, Y.Shirataki, J.Murata, D.Darnaedi, N.Matsuura, M.Ubukata
    • Journal Title

      Heterocycles 60

      Pages: 159-166

    • NAID

      110004639225

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Usage of tautomycin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.2003

    • Author(s)
      S.Mitsuhashi, H.Shima, N.Tanuma, N.Matsuura, M.Takekawa, T.Urano, T.Kataoka, M.Ubukata, K.Kikuchi
    • Journal Title

      J.Biol.Chem. 278

      Pages: 82-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Synthetic studies of proanthocyanidins. Part 3 : Stereoselective 3,4-cis catechin and catechin condensation by TMSOTf-catalyzed intramolecular coupling method.2003

    • Author(s)
      A.Saito, N.Nakajima, A.Tanaka, M.Ubukata
    • Journal Title

      Tetrahedron Lett. 44

      Pages: 5449-5452

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] New luteolin 3'-O-acylated rhamnosides from leaves of Bursera graveolens.2003

    • Author(s)
      T.Nakanishi, Y.Inatome, S.Arai, T.Yamada, H.Fukase, H.Murata, A.Inada, N.Matsuura, M.Ubukata, J.Murata, M.Iinuma, M.Farrea, T.Tanaka
    • Journal Title

      Heterocyles 60

      Pages: 2077-2083

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Three new trimeric stilbenes from Gnetum gnemon.2003

    • Author(s)
      I.Iliya, Z.Ali, T.Tanaka, M.Iinuma, M.Furusawa, K.Nakaya, Y.Shirataki, J.Murata, D.Darnaedi, N.Matsuura, M.Ubukata
    • Journal Title

      Chem.Parm.Bull 51

      Pages: 85-88

    • NAID

      110004639227

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Journal Article] Ascochlorin derivatives as ligands for nuclear hormone receptors.2003

    • Author(s)
      M.Togashi, S.Ozawa, S.Abe, T.Nishimura, M.Tsuruga, K.Ando, G.Tamura, S.Kuwahara, M.Ubukata, J.Magae
    • Journal Title

      J.Med.Chem. 46

      Pages: 4113-4123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380085
  • [Patent] メイラード反応抑制剤2010

    • Inventor(s)
      生方信, 永松龍一郎, 三橋進也
    • Industrial Property Rights Holder
      国立大学法人北海道大学
    • Industrial Property Number
      2010-038455
    • Filing Date
      2010-02-24
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Patent] メイラード反応抑制剤2010

    • Inventor(s)
      生方信, 他2名
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2010-038455
    • Filing Date
      2010-02-24
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 新規オートファジー誘導物質(+)-エポジムノラクタムの構造活性相関2017

    • Author(s)
      岡戸祐治、上田一貴、重冨顕吾、生方 信
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都女子大(京都府・京都)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] 小さな分子から生命が見える2016

    • Author(s)
      生方 信
    • Organizer
      平成28年度 公益社団法人 日本農芸化学会 北海道支部第2回講演会
    • Place of Presentation
      北海道大学(北海道・札幌)
    • Year and Date
      2016-11-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] (+)Epogymnolactam の類縁体合成ならびにオートファジー誘導活性評価2016

    • Author(s)
      上田一貴、岡田祐治、重冨顕吾、生方 信
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌)
    • Year and Date
      2016-03-30
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] Lessons from biologically active natural products - Discovery of new growth factors for previously uncultured Leucobacter sp.2016

    • Author(s)
      M. Ubukata
    • Organizer
      BIT's Annual Congress of International Drug discovery Science and Technology -South Korea 2016
    • Place of Presentation
      Korea International Exhibition Center (Gyeonggi, South Korea)
    • Year and Date
      2016-06-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] オートファジー誘導物質(+)-Epogymnolactamの類縁体合成および活性評価2016

    • Author(s)
      上田一貴、岡戸祐治、重冨顕吾、生方 信
    • Organizer
      日本木材学会北海道支部・平成28年度研究発表会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌)
    • Year and Date
      2016-11-10
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] 終末糖化産物(AGEs)阻害剤 ー 抽出成分と酸素のインパクト2016

    • Author(s)
      生方 信
    • Organizer
      日本木材学会北海道支部 平成28年度研究発表会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌)
    • Year and Date
      2016-11-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] (-)-Epogymnolactamの合成研究2015

    • Author(s)
      上田一貴、岡戸祐治、重冨顕吾、生方 信
    • Organizer
      日本木材学会北海道支部・平成27年度(第47回)研究発表会
    • Place of Presentation
      旭川地場産業振興センター(北海道・旭川)
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] Sphingomonas sp.GF9株の生産するCatellibacterium nectariphilum AST4T株生育因子の単離2014

    • Author(s)
      三橋 進也、Mohammad Nazrul Islam Bhuiyan、重冨 顕吾、高井 亮吾、鎌形 洋一、生方 信
    • Organizer
      日本農芸化学会2014年度(平成26年度)大会
    • Place of Presentation
      神奈川県川崎市明治大学生田キャンパス
    • Data Source
      KAKENHI-PROJECT-25660051
  • [Presentation] オートファジー誘導物質(+)-Epogymnolactamの単離・構造決定および全合成2014

    • Author(s)
      岡戸祐治、新藤千波耶、重冨顕吾、三橋進也、生方 信
    • Organizer
      日本農芸化学会 北海道支部講演会
    • Place of Presentation
      北海道大学学術交流会館(札幌市)
    • Year and Date
      2014-12-13
    • Data Source
      KAKENHI-PROJECT-26450135
  • [Presentation] Study on the novel substrate of protein phosphatase type 1 using tautomycetin2010

    • Author(s)
      Y. Li, S. Mitsuhashi, M. Ubukata
    • Organizer
      日本農芸化学会2010年度大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 農業残渣から調製したシリカ担持ニッケル触媒の特性2010

    • Author(s)
      生方信, 他
    • Organizer
      第60回日本木材学会大会
    • Place of Presentation
      宮崎
    • Year and Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Tautomycetin の合成研究 (2)2010

    • Author(s)
      重冨顕吾, 佐藤文彦, 生方信
    • Organizer
      日本農芸化学会2010年度大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Tautomycetin, a specific PP1 inhibitor suppresses the TNFα/Nf-κB pathway via inhibition of IKK activation.2009

    • Author(s)
      M.Ubukata
    • Organizer
      BIT Life Science 2nd Annual Cancer World Cancer Congress 2009
    • Place of Presentation
      Beijing, China
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 6-Tuliposide Bの類縁体合成と構造活性相関研究2009

    • Author(s)
      重冨顕吾、三橋進也、荘司種明、生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] a specific PP1 inhibitor suppresses the TNFα/NF-κB pathway via inhibition of IKK activation2009

    • Author(s)
      M. Ubukata, Tautomycetin
    • Organizer
      BIT Life Sciences' 2nd Annual Cancer World Cancer Congress 2009
    • Place of Presentation
      Beijing, China.
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 6-Tuliposide Bの不斉合成と構造-抗真菌活性相関2009

    • Author(s)
      大本笑子、重冨顕吾、加藤康夫、生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 生理活性物質トウトマイセチンを使ったPP1の役割と機能解析12009

    • Author(s)
      三橋進也, 岡日只士, 島礼, 菊池九二三, 生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Tautomycetinの合成研究2009

    • Author(s)
      佐藤文彦、大本笑子、生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 生理活性物質トウトマイセチンを使ったPP1の役割と機能解析12009

    • Author(s)
      三橋進也、岡田只士、島礼、菊池九二三、生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Tautomycetin, suppresses the TNFα/NF-κB pathway via inhibition of IKK activation.2009

    • Author(s)
      M.Ubukata
    • Organizer
      The Paulo A.Grieco Symposium
    • Place of Presentation
      Bozeman, USA
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] トウトマイセチンの合成研究2009

    • Author(s)
      佐藤文彦, 大本笑子, 上生方信
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 私と微生物-微生物の生産する生物活性物質の化学と生物学2009

    • Author(s)
      生方信
    • Organizer
      北海道大学大学院農学研究院 寄附分野「微生物新機能開発学分野」開設式・記念講演会
    • Place of Presentation
      札幌
    • Year and Date
      2009-12-08
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 低分子リグニンによるNF-kBの活性化の抑制2008

    • Author(s)
      三橋進也, 岸本崇生, 浦木康光, 生方信
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      名城大学天白キャンパス(名古屋)
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Usage of tautomycetin reveals that protein serin/threonine phophatasel positively regulates NF-・B signaling2008

    • Author(s)
      Y. Li, S. Mitsuhashi, M. Ubukata
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      名城大学天白キャンパス(名古屋)
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 抗菌活性物質6-tuliposide Bの全合成2008

    • Author(s)
      重冨顕吾、岸本崇生、荘司和明 生方 信
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      名白大学天白キャンパス(名古屋)
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Presentation] Usage of tautomycetin reveals that protein serine/threonine phosphatase 1 positively regulates NF-κB signaling2008

    • Author(s)
      Y. Li, S. Mitsuhashi, M. Ubukata
    • Organizer
      日本農芸化学会2008年度大会2008年度大会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] 抗菌活性物質6-tuliposide Bの全合成2008

    • Author(s)
      重冨顕吾, 岸本崇生, 荘司和明, 生方信
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      名城大学天白キャンパス(名古屋)
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] "Screenings of small molecules for modulation of adipocyte differentiation from natural resources"2007

    • Author(s)
      M. Ohashi, S. Mitsuhashi, M. Ubukata
    • Organizer
      14th International Symposium of Wood, Fiber, pulping Chemistry
    • Place of Presentation
      ダーバン国際コンベンションセンター(Durban)
    • Year and Date
      2007-06-26
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Presentation] Analysis of the role of protein phosphatase type 1 in TNFα/NF-κB pathway by using tautomycetin2007

    • Author(s)
      Y. Li, S. Mitsuhashi, M. Ubukata
    • Organizer
      平成19年度第一回学術講演会
    • Place of Presentation
      札幌
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] ミコフェノール酸及びその誘導体を用いた細胞分化調節活性の構造活性相関2007

    • Author(s)
      竹中淳一、三橋進也、生方 信
    • Organizer
      第19回万有札幌シンポジウム
    • Place of Presentation
      北海道厚生年金会館(札幌)
    • Year and Date
      2007-07-07
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Presentation] ミコフェノール酸の新たな生理活性と構造活性相関2007

    • Author(s)
      三橋進也、竹中淳一、大橋水咲 生方 信
    • Organizer
      日本生化学会・日本分子生物学会合同大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-18032006
  • [Presentation] Analysis of the role of protein phosphatase type 1 in TNF a/NF-kB path way by using tautomycetin2007

    • Author(s)
      Y. Li, S. Mitsuhashi, M. Ubukata
    • Organizer
      平成19年度第一回合同学術講演会
    • Place of Presentation
      北海道大学農学部総合研究棟多目的室(札幌)
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-19208011
  • [Presentation] Sphingomonas sp.の異種バクテリアに対する増殖因子の探索

    • Author(s)
      髙井 亮吾、Mohammad Nazrul Islam Bhuiyan、三橋 進也、鎌形 洋一、生方 信
    • Organizer
      日本木材学会北海道支部・平成25年度研究発表会
    • Place of Presentation
      北海道旭川市大雪クリスタルホール
    • Data Source
      KAKENHI-PROJECT-25660051
  • [Presentation] Growth promoting compound produced by Sphingomonas sp. (GF9) for vigorous growth of Catellibacterium nectariphilum strain AST4T.

    • Author(s)
      Mohammad Nazrul Islam Bhuiyan, Shinya Mitsuhashi, Kengo Shigetomi, Yoichi Kamagata, Makoto Ubukata
    • Organizer
      平成25年度公益社団法人日本農芸化学会北海道支部夏期シンポジウム
    • Place of Presentation
      北海道旭川市国際会議場
    • Data Source
      KAKENHI-PROJECT-25660051
  • 1.  MITSUHASHI Shinya (60526672)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 2.  SHIGETOMI Kenngo (20547202)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 3.  MATSUURA Nobuyasu (60281250)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 4.  DAIRI Tohru (70264679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  磯野 清 (70087542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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