Sugai Takeshi 須貝威

… Alternative Names

SUGAI Takeshi 須貝威

須貝威スガイタケシ

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Researcher Number	60171120
Other IDs
External Links
Affiliation (Current)	2025: 東京大学, 総括プロジェクト機構, 特任研究員 2025: 東京大学, 大学院理学系研究科(理学部), 特任研究員
Affiliation (based on the past Project Information) *help	2019 – 2021: 慶應義塾大学, 薬学部(芝共立), 教授 2016: 慶應義塾大学, 薬学部(芝共立), 教授 2008 – 2015: Keio University, 薬学部, 教授 2007: Keio University, Chemistry, Associate Professor 2000 – 2006: 慶應義塾大学, 理工学部, 助教授 … More 1997 – 1998: 慶應義塾大学, 理工学部, 助教授 1996: 慶應義塾大学, 理工学部, 専任講師 1995: 慶応義塾大学, 理工学部, 専任講師 1993: 慶應義塾大学, 理工学部, 専任講師 1988: The University of Tokyo, 農学部, 助手 1988: 東京大学, 農学部農芸化学科, 助手 1986: 東京大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Bioproduction chemistry/Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / Basic Section 38040:Bioorganic chemistry-related / Bioorganic chemistry Except Principal Investigator 製造化学・食品 / Hematology / Chemical biology / Chemical biology
Keywords	Principal Investigator リパーゼ / 速度論的光学分割 / 加水分解 / 有機化学 / 天然物合成 / 生物資源 / アミノ酸 / 酵母還元 / 微生物酵素 / kinetic resolution … More / Kinetic Resolution / アミノ糖 / 脱アセチル化 / ポリフェノール / 位置選択的反応 / 立体選択的反応 / 応用微生物 / 酵素 / バイオリアクター / ニトリルヒドラターゼ / 配糖体 / 酵素触媒 / カタセラスモール類 / 鎖状ポリオール / アセチル化 / メトキシル化 / ハロゲン化 / 天然配糖体 / 半合成 / ポリオール / 高圧蒸気滅菌器 / applied microbiology / enzymes / bioreactor / organic chemistry / 酸素 / バイリアクター / amino acids / natural product synthesis / yeast reduction / microbial enzymes / 環境受容型反応 / Amino Acid / Natural Product Synthesis / Yeast-mediated Reduction / Microbial Enzymes / 加水分解酵素 / glycoconjugates / functional group transformation / reduction / hydrolysis / Biocatalysts / パパイン / Rhodococcus rhodochrous / N-アセチルグルコサミン / シアノヒドリン / エステラーゼ / 光学活性カルボン酸 / 複合糖質 / 官能基変換 / 還元 / 速度論的光子分割 / 微生物酵素触媒 / Regioselective Acylation / Amino Sugar / Pheromone / Lipase / Ceramide / Amino Alcohol / 〔3,3〕-シグマトロピー転位 / 位置選択的保護 / グリカ-ル / フェリエ反応 / 位置選択的アシル化 / フェロモン / セラミド / アミノアルコール / 遠隔位不斉中心 / エステル交換 / 速度論的分割 / 含窒素複素環 / 複素環化合物 / リパーゼ触媒 / 応用微生物学 / 糖質化学 / 酵素合成 / 位置選択的加水分解 / 微生物還元 / 遠隔不斉認識 / 鏡像選択性 / 光学活性合成原料 / 一級アルコール / エステル化 / アシル化 / 光学分割 / アレニルアルコール / アレン / ニトリル / アセタール / ピレノホリン / 微生物不斉還元 / 界面バイオリアクター / 炭素-炭素結合形成 / ピルビン酸脱炭酸酵素 … More Except Principal Investigator 転移 / 分子デザイン / DHMEQ / phytoalexin / natural sweetner / antibiotics / insect juvenile hormone / pheromone / optically active compound / synthesis / bioactive substances / 昆虫攝食阻害物質 / 甘味料 / 昆虫摂食阻害物質 / ファイトアレキシン / 天然甘味剤 / 抗生物質 / 昆虫幼若ホルモン / フェロモン / 光学活性体 / 合成 / 生物活性物質 / nucleophosmin-1 / 上皮間葉系移行 / 髄外病変 / 免疫調節薬 / TC11 / TP53 / 多発性骨髄腫 / 薬学 / 内科 / Exo-ene EQ / (-)-DHMEQ / 放線菌 / SEMBL / 分子標的 / スクリーニング / 阻害剤 / desmal / 炎症 / がん / 天然物 / NF-kappa B / 抗癌剤 / 浸潤 / 腹腔内播種 / 卵巣癌 / NF-κB Less

Synthetic Studies of Bioactive Substances Based on Site- and Stereoselective ReactionsPrincipal Investigator
- Principal Investigator
  
  Sugai Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Keio University
Screening of NF-kappa B inhibitors having new core structure and application to aggressive cancer treatment
- Principal Investigator
  
  Umezawa Kazuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Aichi Medical University
Efficient organic synthesis utilizing microbial enzyme catalystsPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Keio University
Drug discovery based on novel concept for overcoming high-risk myeloma which is still intractable despite of recent progress in the treatment
- Principal Investigator
  
  Hattori Yutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Design and synthesis of highly efficient substrate compatible to chemo-enzymatic synthesisPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
Fine chemical production by complementary use of microbial catalysts and organic synthesisPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
Molecular design and synthesis of soluble NF-κB inhibitor and suppression of ovarian carcinoma
- Principal Investigator
  
  UMEZAWA Kazuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Keio University
Screeing of novel microbial- and enzyme catalysts for expeditious chemical synthesis of useful substancesPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
Chemo-enzymatic Synthesis of Biologically Active Compounds based on Biocatalysts and BioresourcesPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  KEIO UNIVERSITY
Development of Microbial Enzymatic Catalysts towards the Chemo-Enzymatic Synthesis of Bioactive SubstancesPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
Organic synthesis and Production based on Bioresources and BiocatalysisPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
複雑な天然物合成の基盤となる生化学的変換反応の捜索Principal Investigator
- Principal Investigator
  
  須貝威
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
生化学的官能基変換反応の開発と天然物合成への応用Principal Investigator
- Principal Investigator
  
  須貝威
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Keio University
Screening of New Biocatalysts and Its Application to the Synthesis of Biologically Active CompoundsPrincipal Investigator
- Principal Investigator
  
  SUGAI Takeshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Depatment of Chemistry, Keio University
生物活性物質の合成研究に有用な生体触媒反応の開発Principal Investigator
- Principal Investigator
  
  須貝威
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
生体触媒による反応を利用した生物活性物質の合成研究Principal Investigator
- Principal Investigator
  
  須貝威
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Keio University
生体触媒を利用したシアリル糖鎖誘導体のハイブリッド合成Principal Investigator
- Principal Investigator
  
  須貝威
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
Synthesis of Optically Active Forms of Some Useful Bioactive Substanus
- Principal Investigator
  
  MORI Kenji
- Project Period (FY)
  1985 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  製造化学・食品
- Research Institution
  The University of Tokyo

[Book] Site-selective lipase-catalyzed acylation and deacylation in the synthesis of valuable carbohydrates and flavonoids from naturally abundant starting materials2017
- Author(s)
  R. Tsunekawa, K. Hanaya, M. Shoji, T. Sugai
- Total Pages
  17
- Publisher
  Elsevier B. V.
- Data Source
  KAKENHI-PROJECT-26450143
[Book] 有機合成実験法ハンドブック第2版2015
- Author(s)
  須貝威、古田未有
- Total Pages
  3
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-26450143
[Book] 位置・立体選択的反応を鍵段階とする酵素-化学複合合成法の開発、「複合糖質の化学と最新応用技術」(正田晋一郎、稲津敏行編)2009
- Author(s)
  橘田和憲, 濱田学, 梅澤一夫, 東利則, 須貝威
- Total Pages
  9
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-20611015
[Book] Practical Methods for Biocatalysis and Biotransformations (J.Whittal, P.W.Sutton,eds.) (Epoxide Hydrolase Catalyzed Synthesis of (R)-3-benzyloxy-2-methylpropane-1,2-diol)2009
- Author(s)
  T.Sugai, A.Fujino, H.Yamaguchi, M.Ikunaka
- Data Source
  KAKENHI-PROJECT-20580114
[Book] 複合糖質の化学と最新応用技術(正田晋一郎、稲津敏行編)(位置・立体選択的反応を鍵段階とする酵素-化学複合合成法の開発)2009
- Author(s)
  橘田和憲、濱田学、梅澤一夫、東利則、須貝威
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-20580114
[Book] 酵素反応のスケールアップ-トラブル解決へのヒント-2008
- Author(s)
  須貝威, 濱田学
- Total Pages
  12
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-20580114
[Book] 酵素反応のスケールアップ-トラブル解決へのヒント-鳥澤保廣編、「創薬支援研究の展望」2008
- Author(s)
  須貝威、濱田学
- Publisher
  シーエムシー
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Book] 酵素反応のスケールアップートラブル解決へのヒントー;鳥澤保廣編、「創薬支援研究の展望」2008
- Author(s)
  須貝威、浜田学
- Total Pages
  222
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] mproved preparation of vitexin from hot water extract of Basella alba, the commercially Malabar spinach (“Tsurumurasaki” in Japanese) and the application to semisynthesis of chafuroside B2020
- Author(s)
  Kazuki Kurahayashi, Kengo Hanaya, Shuhei Higashibayashi, Takeshi Sugai
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 8 Pages: 1554-1559
- DOI
  10.1080/09168451.2020.1761286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05849
[Journal Article] Comprehensive Semisyntheses of Catathelasmols C, D, and E from D-Glutamic Acid, Utilizing Lipase-catalyzed Site-selective Reactions on Intermediates2020
- Author(s)
  Rinta Hashiba, Riichi Hashimoto, Momoko Nishiguchi, Toshifumi Kobayashi, Kengo Hanaya, Shuhei Higashibayashi, and Takeshi Sugai
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 7 Pages: 1339-1344
- DOI
  10.1080/09168451.2020.1754159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05849
[Journal Article] Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation2017
- Author(s)
  Y. Yamashita, A. Biard, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: － Issue: 7 Pages: 1279-1284
- DOI
  10.1080/09168451.2017.1303362
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450143
[Journal Article] Preparation of (R)-3-hydroxy-N-methylpiperidine, a synthetic key intermediate of (R)-mepenzolate, based on the lipase-catalyzed resolution of the racemic form.2017
- Author(s)
  Yamashita, Y., Hanaya, K., Shoji, M., and Sugai, T.
- Journal Title
  
  Heterocycles
  
  Volume: 95 Issue: 1 Pages: 370-379
- DOI
  10.3987/com-16-s(s)28
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J00535, KAKENHI-PROJECT-26450143
[Journal Article] Simple Synthesis of Sakuranetin and Selinone via a Common Intermediate, Utilizing Complementary Regioselectivity in the Deacetylation of Naringenin Triacetate2016
- Author(s)
 Y. Yamashita, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 64 Issue: 7 Pages: 961-965
- DOI
 10.1248/cpb.c16-00190
- NAID
 130005160036
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26450143
[Journal Article] New Synthesis of Artepillin C, a Prenylated Phenol, Utilizing Lipase-catalyzed Regioselective Deacetylation as the Key Step2015
- Author(s)
  K. Yashiro, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 79 Issue: 12 Pages: 1926-1930
- DOI
  10.1080/09168451.2015.1058704
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450143
[Journal Article] (-)-Benzyl 2,3-dideoxy-β-D-erythro-hex-2-enopyranoside2014
- Author(s)
  S. Ohba, H. Okazaki, Y. Ueda, K. Hanaya, T. Sugai
- Journal Title
  
  Acta Cryst. Sect. E
  
  Volume: E69 Issue: 12 Pages: o1811-o1811
- DOI
  10.1107/s1600536813031140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] Recognition of the remote chiral center in lipase-catalyzed kinetic resolution of [2-methyl-2-(2′-naphthyl)-1,3-benzodioxol-4-yl]methyl acetate, the precursor of 2-methyl-2-(2′-naphthyl)-1,3-benzodioxole-4-carboxylic acid (MNB carboxylic acid)2014
- Author(s)
  N. Natori, K. Nakagawara, M. Shoji, T. Sugai, K. Hanaya
- Journal Title
  
  Journal of Molecular Catalysis B: Enzymatic
  
  Volume: 109 Pages: 130-135
- DOI
  10.1016/j.molcatb.2014.08.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450143
[Journal Article] An expeditious route for 2-acetamido-4-O-methyl-2-deoxy-D-mannopyranose from a Ferrier derivative of tri-O-acetyl-D-glucal, which contributes to the synthesis of laninamivir (CS-8958), a neuraminidase inhibitor2013
- Author(s)
  H. Okazaki, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 37 Pages: 7931-7935
- DOI
  10.1016/j.tet.2013.07.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152, KAKENHI-PROJECT-25460131
[Journal Article] Chemo-enzymatic transformation of naturally abundant naringin to luteolin, a flavonoid with various biological effects2013
- Author(s)
  R. Kobayashi, T. Itou, K. Hanaya, M. Shoji, N. Hada, T. Sugai
- Journal Title
  
  J. Mol. Catal. B : Enz
  
  Volume: 92 Pages: 14-18
- DOI
  10.1016/j.molcatb.2013.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152, KAKENHI-PROJECT-25460131
[Journal Article] Synthesis of (R)-bambuterol based on asymmetric reduction of 1-[3,5-bis(dimethylcarbamoyloxy)phenyl]-2- chloroethanone with incubated whole cells of Williopsis californica JCM 36002013
- Author(s)
  K. Asami, T. Machida, S. Jung, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
  
  J. Mol. Catal. B : Enz
  
  Volume: 97 Pages: 106-109
- DOI
  10.1016/j.molcatb.2013.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] Whole-cell yeast-mediated preparation of (R)-2-chloro-1-(3-nitro phenyl)ethanol as a synthetic precursor for (R)-phenylephrine2013
- Author(s)
  D. Tokoshima, K. Hanaya, M. Shoji, T. Sugai
- Journal Title
  
  J. Mol. Catal. B : Enz
  
  Volume: 97 Pages: 95-99
- DOI
  10.1016/j.molcatb.2013.07.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] Towards the Integrated Exploitation of Microbial and Enzymatic Catalysis — Importance of Substrate Molecular Technology and Quest of Biocatalysts, for Designing Synthetic Plans2013
- Author(s)
  古田未有、花屋賢悟、庄司満、須貝威
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 71 Issue: 3 Pages: 237-246
- DOI
  10.5059/yukigoseikyokaishi.71.237
- NAID
  10031157230
- ISSN
  0037-9980, 1883-6526
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] Chemo-enzymatic routes for (R)-terbutaline hydrochloride based on microbial asymmetric reduction of a-haloacetophenones2012
- Author(s)
  S. Taketomi, M. Asano, T. Higashi, M. Shoji and T. Sugai
- Journal Title
  
  J. Mol. Catal. B: Enz.
  
  Volume: 84 Pages: 83-88
- DOI
  10.1016/j.molcatb.2012.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] A Chemo-Enzymatic Expeditious Route to Racemic Dihexanoyl (2R*,3R*,4R*)-Dehydroxymethylepoxyquinomycin (DHMEQ), the Precursor for Lipase-Catalyzed Synthesis of the Potent Nuclear Factor-κB Inhibitor, (2S,3S,4S)-DHMEQ2012
- Author(s)
 R. Kobayashi, K. Hanaya, M. Shoji, K. Umezawa, T. Sugai
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 60 Issue: 9 Pages: 1220-1223
- DOI
 10.1248/cpb.c12-00417
- NAID
 130001852541
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23580152
[Journal Article] Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a new activator of antioxidant transcription factor Nrf22011
- Author(s)
  Y. Niitsu, M. Hakamata, Y. Goto, T. Higashi, M. Shoji, T. Sugai and K Umezawa
- Journal Title
  
  Organic & Biomolecule Chemistry
  
  Volume: 9 Issue: 12 Pages: 4635-4641
- DOI
  10.1039/c1ob05205e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580152
[Journal Article] 新しいNF-κB阻害剤DHMEQの生物有機化学と抗炎症・抗がん剤への展望2011
- Author(s)
  須貝威、梅澤一夫
- Journal Title
  
  化学と生物
  
  Volume: (掲載確定)
- Data Source
  KAKENHI-PROJECT-20611015
[Journal Article] New chemo-enzymatic route toward N-acetylneuraminic acid derivatives with alkyl groups at C-7 hydroxyl group2010
- Author(s)
  J.Calveras, Y.Nagai, I.Sultana, Y.Ueda, T.Higashi, M.Shoji, T.Sugai
- Journal Title
  
  Tetrahedron 66
  
  Pages: 4284-4291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Elaboration on the access to (S)-4-(4-methylbenzyl)oxy-3-hydroxybutanenitrile, a key intermediate for statins, by combining the kinetic resolution of racemate and the recycle of undesired enantiomer2010
- Author(s)
  M.Sakamoto, M.Hamada, T.Higashi, M.Shoji, T.Sugai
- Journal Title
  
  J.Mol.Catal.B : Enz.
  
  Volume: 64 Pages: 96-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Chemo-enzymatic Synthesis of Both Enantiomers of 2-tert-Butyl-2-methyl-1,3-benzodioxole-4-car boxylic (TBMB) Acid2010
- Author(s)
  T.Higashi, C.Abe, K.Ninomiya, T.Machida, N.Chishima, S.Taketomi, M.Furuta, Y.Komaki, Y.Senba, T.,Tokuda M.Shoji, T.Sugai
- Journal Title
  
  Adv.Synth.Catal. 352
  
  Pages: 2549-2558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Chemo-enzymatic Synthesis of Both Enantiomers of 2-tert-Butyl-2-methyl-1,3-benzodioxole-4-carboxylic (TBMB) Acid2010
- Author(s)
  T.Higashi, C.Abe, K.Ninomiya, T.Machida, N.Chishima, S.Taketomi, M.Furuta, Y.Komaki, Y.Senba, T.Tokuda, M.Shoji, T.Sugai
- Journal Title
  
  Adv.Synth.Catal
  
  Volume: 352 Pages: 2549-2558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Chemoenzymatic synthesis of (2S,3S,4S)-form, the physiologically active stereoisomer of dehydroxymethylepoxyquinomicin (DHMEQ), a potent inhibitor on NF-κB.2010
- Author(s)
  M.Hamada, T.Sugai, K.Umezawa, et al
- Journal Title
  
  Tetrahedron
  
  Volume: 66 Pages: 7083-7087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611015
[Journal Article] The scope and limitation on the regio- and enantioselective hydrolysis of aliphatic epoxides by Bacillus subtilis epoxide hydrolase, and exploration towards chirally differentiated tris(hydroxymethyl)methanol2010
- Author(s)
  K.Shimizu, M.Sakamoto, M.Hamada, T.Higashi, T.Sugai, M.Shoji
- Journal Title
  
  Tetrahedron : Asymmetry 21
  
  Pages: 2043-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] The scope and limitation on the regio- and enantioselective hydrolysis of aliphatic epoxides by Bacillus subtilis epoxide hydrolase, and exploration towards chirally differentiated tris(hydroxymethyl)methanol2010
- Author(s)
  K.Shimizu, M.Sakamoto, M.Hamada, T.Higashi, T.Sugai, M.Shoji
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 21 Pages: 2043-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Chemoenzymatic synthesis of (2S,3S,4S)-form2010
- Author(s)
  M. Hamada, Y. Niitsu, C. Hiraoka, I. Kozawa, T. Higashi, M. Shoji, K. Umezawa, T. Sugai
- Journal Title
  
  the physiologically active stereoisomer of dehydroxymethylepoxyquinomicin (DHMEQ), a potent inhibitor on NF-κB. Tetrahedron 66
  
  Pages: 7083-7087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611015
[Journal Article] A Short-step Chemo-enzymatic Synthesis of a Precursor for L-Nucleosides from D-Lyxose2009
- Author(s)
  K.Kitsuda, J.Calveras, Y.Nagai, T.Higashi, T.Sugai
- Journal Title
  
  J.Mol.Catal.B : Enz. 59
  
  Pages: 197-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] A Short-step Chemo-enzymatic Synthesis of a Precursor for L-Nucleo sides from D-Lyxose2009
- Author(s)
  K.Kitsuda, J.Calveras, Y.Nagai, T.Higashi, T.Sugai
- Journal Title
  
  Journal of Molecular Catalysis, B : Enzymatic 59
  
  Pages: 197-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Enzyme-catalyzed enantiomeric resolution of 3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylic esters and the application to the synthesis of 3-epishikimic acid2009
- Author(s)
  M.Hamada, Y.Inami, Y.Nagai, T.Higashi, M.Shoji, S.Ogawa, K.Umezawa, T.Sugai
- Journal Title
  
  Tetrahedron : Asymmetry 20
  
  Pages: 2105-2111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Chemoenzymatic Approach to Enantiomerically Pure (R)-3-Hydroxy-3-methyl-4-pentenoic Acid Ester and Its Application to Formal Total Synthesis of Taurospongin A2008
- Author(s)
  A. Fujino, T. Sugai
- Journal Title
  
  Advanced Synthesis and Catalysis 350
  
  Pages: 1712-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] Regio- and chemoselective manipulation under mild conditions on glucosamine derivatives for oligosaccharide synthesis and its application to wards N-acetyl-D-lactosamine and Lewis X trisaccharide2008
- Author(s)
  Y. Nagai, N. Ito, I. Sultana, T. Sugai
- Journal Title
  
  Tetrahedron 64
  
  Pages: 9599-9606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580114
[Journal Article] First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargy1 ketone2007
- Author(s)
  M. Matsuda, T. Yamazaki, K. Fuhshuku, T.Sugai
- Journal Title
  
  Tetrahedron 63
  
  Pages: 8752-8760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] First total synthesis of modiolide A,based on the whole-cell yeast-cat alyzed asymmetric reduction of a propargyl ketone2007
- Author(s)
  M.Matsuda, T.Yamazaki, K.Fuhshuku, T.Sugai
- Journal Title
  
  Tetrahedron 63
  
  Pages: 8752-8760
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Bacillus subtilis epoxide hydrolase-catalyzed preparation of enantiopure 2-methylpropane-1, 2, 3-triol monobenzyl ether and its application to expeditious synthesis of (R)-bicalutamide2007
- Author(s)
  A., Fujino, M., Asano, H., Yamaguchi, N., Shirasaka, A., Sakoda, M., Ikunaka, R., Obata, S., Nishiyama, T., Sugai
- Journal Title
  
  Tetrahedron Lett 48
  
  Pages: 979-983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone2007
- Author(s)
  M., Matsuda, T., Yamazaki, K., Fuhshuku, T., Sugai
- Journal Title
  
  Tetrahedron 63
  
  Pages: 8752-8760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Bacillus subtilis epoxide hydrolase-catalyzed preparation of enantiopure 2-methylpropane-1,2,3-triol monobenzyl ether and its application to expeditious synthesis of(R)-bicalutamide2007
- Author(s)
  A.Fujino, M.Asano, H.Yamaguchi, N.Shirasaka, A.Sakoda, M.Ikunaka, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 979-983
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Bacillus subtilis epoxide hydrolase-catalyzed preparation of enantiopure 2-methylpropane-1,2,3-triol monobenzyl ether and its application to expeditious synthesis of (R)-bicalutamide2007
- Author(s)
  A. Fujino, M. Asano, H. Yamaguchi, N. Shirasaka, A. Sakoda, M. Ikunaka, R. Obata, S. Nishiyama, T. Sugai
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 979-983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Screening,substrate specificity and stereoselectivity of yeast strains,which reduce sterically hindered isopropyl ketones2006
- Author(s)
  C.Hiraoka, M.Matsuda, Y.Suzuki, S.Fujieda, M.Tomita, K.Fuhshuku, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Tetrahedron:Asymmetry 17
  
  Pages: 3357-3368
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] 酵素・微生物触媒反応を基盤とする有用物質合成への展開2006
- Author(s)
  冨宿賢一, 西山繁, 須貝威
- Journal Title
  
  有機合成化学協会誌 64
  
  Pages: 664-676
- NAID
  10019174396
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] 物質合成の設計図にブレークスルーを : 酵素触媒の活躍と未来2006
- Author(s)
  須貝威
- Journal Title
  
  バイオインダストリー 23
  
  Pages: 5-6
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] 酵素光学分割を基盤とする、光学活性アミノ酸・アミノアルコール調製に向けたプロセス開発2006
- Author(s)
  須貝威, 冨宿賢一, 小畠りか, 西山繁
- Journal Title
  
  ケミカルエンジニヤリング 51
  
  Pages: 691-696
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Screening, substrate specificity and stereoselectivity of yeast strains, which reduce sterically hindered isopropyl ketones2006
- Author(s)
  C.Hiraoka, M.Matsuda, Y.Suzuki, S.Fujieda, M.Tomita, K.Fuhshuku, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Tetrahedron : Asymmetry 17
  
  Pages: 3357-3368
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] Screening, substrate specificity and stereoselectivity of yeast strains, which reduce sterically hindered isopropyl ketones2006
- Author(s)
  C., Hiraoka, M., Matsuda, Y., Suzuki, S., Fujieda, M., Tomita, Fuhshuku, R., Obata, S., Nishiyama, T., Sugai
- Journal Title
  
  Tetrahedron : Asymmetry 17
  
  Pages: 3357-3368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Journal Article] 生命分子の変化をつかさどるタンパク触媒-酵素-触媒のしくみ,鏡像異性とのかかわりから物質合成まで2005
- Author(s)
  須貝威, 浅野正義
- Journal Title
  
  化学と教育 53
  
  Pages: 436-439
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Chemo-enzymatic Route to Both Enantiomers of 1-Isopropyl-3a-methyloctahydroinden-4-one Derivative, a Synthetic Intermediate for Sesqui- and Diterpenoids2005
- Author(s)
  S.Fujieda, M.Tomita, K.Fuhshuku, S.Ohba, S.Nishiyama, T.Sugai
- Journal Title
  
  Adv.Synth.Catal. 347
  
  Pages: 1099-1109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] The Short-step and Scalable Synthesis of (±)-Cytoxazone2005
- Author(s)
  M.Asano, C.Nagasawa, M.Suzuki, S.Nishiyama, T.Sugai
- Journal Title
  
  Biosci.Biotechnol.Biochem 69
  
  Pages: 145-148
- NAID
  130000030565
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] An Efficient Route to (S)-Azetidine-2-carboxylic Acid.2005
- Author(s)
  Y.Futamura, M.Kurokawa, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Biosci.Biotechnol.Biochem 69
  
  Pages: 1892-1987
- NAID
  130000030520
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Chemo-enzymatic Short-step Total Synthesis of Symbioramide2005
- Author(s)
  T.Takanami, H.Tokoro, D.Kato, S.Nishiyama, T.Sugai
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 3291-3295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] An Efficient Route to (S)-Azetidine-2-carbozylic Acid2005
- Author(s)
  Y.Futamura, M.Kurokawa, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Biosci. Biotechnol. Biochem 69
  
  Pages: 1892-1987
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] An Efficient Route to (S)-Azetidine-2-carboxylic Acid2005
- Author(s)
  Y.Futamura, M.Kurokawa, R.Obata, S.Nishiyama, T.Sugai
- Journal Title
  
  Biosci.Biotechnol.Biochem. 69
  
  Pages: 1892-1987
- NAID
  130000030520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Chemo-enzymatic Route to Both Enantiomers of 1-Isopropyl-3a-methyloctahydroinden-4-one Derivative, a Synthetic Intermediate for Sesqui- and Diterpenoids2005
- Author(s)
  S.Fujieda, M.Tomita, K.Fuhshuku, S.Ohba, S.Nishiyama, T.Sugai
- Journal Title
  
  Adv. Synth. Catal. 347
  
  Pages: 1099-1109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] 生命分子の変化をつかさどるタンパク触媒-酵素-触媒のしくみ、鏡像異性とのかかわりから物質合成まで2005
- Author(s)
  須貝威, 浅野正義
- Journal Title
  
  化学と教育 53
  
  Pages: 436-439
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] The Short-step and Scalable Synthesis of (±)-Cytoxazone2005
- Author(s)
  M.Asano, C.Nagasawa, M.Suzuki, S.Nishiyama, T.Sugai
- Journal Title
  
  Biosci. Biotechnol. Biochem 69
  
  Pages: 145-148
- NAID
  130000030565
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Realization of the Synthesis of α,α-Disubstituted Carbamylacetates and Cyanoacetates Either by Chemical or Enzymatic Functional Group Transformation, Depending upon the Substrate Specificity of Rhodococcus amidase2004
- Author(s)
  M.Yokoyama, M.Kashiwagi, M.Iwasaki, K.Fuhshuku, H.Ohta, T.Sugai
- Journal Title
  
  Tetrahedron : Asymmetry 15
  
  Pages: 2817-2820
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Mechanistic Studies on Nitrosation-deaminocyclization of Mono-carbamylated Vicinal Amino Alcohols and Diols : A New Preparative in situ Formation of Ethanediazoic Acid for the Ethylation of Carboxylate under Mild Conditions2004
- Author(s)
  M.Suzuki, T.Sugai
- Journal Title
  
  Bull.Chem.Soc.Jpn 77
  
  Pages: 1217-1227
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Both Enantiomers of N-Boc-indoline-2-carboxylic Esters2004
- Author(s)
  M.Kurokawa, T.Sugai
- Journal Title
  
  Bull.Chem.Soc.Jpn. 77
  
  Pages: 1021-1025
- NAID
  10012940880
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] Mechanistic Studies on Nitrosation-deaminocyclization of Mono-carbamylated Vicinal Amino Alcohols and Diols : A New Preparative in situ Formation of Ethanediazoic Acid for the Ethylation of Carboxylate under Mild Conditions2004
- Author(s)
  M.Suzuki, T.Sugai
- Journal Title
  
  Bull. Chem. Soc. Jpn 77
  
  Pages: 1217-1227
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] A Control of the Nitrile-hydrolyzing Enzyme Activity in Rhodococcus rhodochrous IFO 15564 ; Preferential Action of Nitrile Hydratase and Amidase Depending on the Reaction Condition Factors and its Application to the One-pot Preparation of Amides from Aldehydes2004
- Author(s)
  M.Kashiwagi, K.Fuhshuku, T.Sugai
- Journal Title
  
  J.Mol.Catal.Sect.B enzymatic 29
  
  Pages: 249-258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580092
[Journal Article] 新しいNF-κB阻害剤DHMEQの生物有機化学と抗炎症・抗がん剤への展望
- Author(s)
  須貝威、梅澤一夫
- Journal Title
  
  化学と生物 (印刷中)
- Data Source
  KAKENHI-PROJECT-20611015
[Presentation] 天然・生物活性物質合成を志向した、メトキシベンゼン類の合成研究2022
- Author(s)
  須貝威、Qi Ziyu、本田桂子、橋本理一、小林俊文、花屋賢悟、東林修平
- Organizer
  日本農芸化学会2022年度大会、オンライン
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 位置・官能基選択的酵素触媒反応の、有機合成への応用2021
- Author(s)
  須貝威、橋本理一、本田桂子、花屋賢悟、東林修平
- Organizer
  第37回有機合成化学セミナー、オンライン
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] Development of the synthetic routes utilizing the selectivity in enzyme catalysis2021
- Author(s)
  Sugai T.
- Organizer
  The International Chemical Congress of Pacific Basin Societies, Virtual
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] フラボノイド合成に有用な選択的変換2021
- Author(s)
  須貝威、Qi Ziyu、松島昌輝、井上浩義、花屋賢悟、東林修平
- Organizer
  第50回複素環化学討論会、オンライン
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] Advantages of lipase-catalyzed transformation in organic synthesis2021
- Author(s)
  Sugai T.
- Organizer
  European Federation of Biotechnology Conference 2021, Virtual
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 芳香族メチルエーテルを部分構造に含む天然有機化合物の合成研究2021
- Author(s)
  須貝威、本田桂子、横山芹香、橋本理一、安井将満、花屋賢悟、東林修平
- Organizer
  日本農芸化学会関東支部大会、オンライン
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 芳香族メチルエーテルを部分構造に含む天然有機化合物の合成研究2021
- Author(s)
  本田桂子、横山芹香、橋本理一、安井将満、東林修平、花屋賢悟、須貝威
- Organizer
  第65回日本薬学会関東支部大会、オンライン
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 天然より豊富に得られるアラビノシルビテキシンを出発原料としたチャフロシドBの調製2021
- Author(s)
  倉林一樹、花屋賢悟、東林修平、須貝威
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] リパーゼ触媒による，ポリフェノールアセタート脱アセチル化の位置選択性の検討と応用2020
- Author(s)
  須貝威、橋本理一、花屋賢悟、東林修平
- Organizer
  第22回生体触媒化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] Enzyme-assisted syntheses of bioactive compounds, originated from Scripps days2019
- Author(s)
  Takeshi Sugai
- Organizer
  2019 Scripps Korea Society Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 酵素触媒や生物資源を活用した有用物質合成法への挑戦2019
- Author(s)
  須貝威
- Organizer
  第78回有機合成化学協会関東支部シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K05849
[Presentation] 酵素触媒の位置選択性を活用したポリフェノール類の合成研究2016
- Author(s)
  坂倉彩香, 山下泰信, 恒川龍二, 野城和貴, 花村駿, 花屋賢悟, 庄司満, 須貝威
- Organizer
  生体触媒化学シンポジウム
- Place of Presentation
  明星大学、東京都日野市
- Year and Date
  2016-12-21
- Data Source
  KAKENHI-PROJECT-26450143
[Presentation] Advantage of enzyme-catalyzed acetylation and deacetylation in the synthesis of useful products2016
- Author(s)
  Yamashita Y, Hanaya K, Shoji M, Sugai T
- Organizer
  The Fifth International Conference on Cofactors (ICC-05) and Active Enzyme Molecule 2016 (AEM 2016)
- Place of Presentation
  Kurobe Unazuki International Hall Selene, 富山県黒部市
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450143
[Presentation] 配糖体と酵素触媒を活用する、有用ポリフェノール類の合成研究2015
- Author(s)
  須貝威、花村駿、花屋賢悟、庄司満、木内文之
- Organizer
  日本農芸化学会関東支部2015年度支部大会
- Place of Presentation
  お茶の水女子大学（東京都）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-26450143
[Presentation] Synthesis of Artepillin C, Based on Lipase-Catlayzed Regioselective Deacetylation2015
- Author(s)
  Yashiro, K.; Hanaya, K.; Shoji, M.; Sugai, T.
- Organizer
  Biotrans 2015
- Place of Presentation
  Wiena (Austria)
- Year and Date
  2015-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450143
[Presentation] β-選択的Ferrier反応を鍵段階とする、L-グルコースの合成研究2014
- Author(s)
  岡崎隼人、植田裕二、大場茂、羽田紀康、花屋賢悟、庄司満、須貝威
- Organizer
  日本化学会大94春季年会
- Place of Presentation
  名古屋大学
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] リパーゼによる遠隔位不斉認識を利用したMNBカルボン酸の合成2014
- Author(s)
  名取直輝、花屋賢悟、庄司満、須貝威
- Organizer
  有機合成化学協会関東支部シンポジウム
- Place of Presentation
  慶應義塾大学理工学部（横浜）
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-26450143
[Presentation] つねに再生・進化する酵素・バイオ触媒～ファインケミカル合成における活用2012
- Author(s)
  須貝威
- Organizer
  第二回CSJ化学フェスタ2012
- Place of Presentation
  東京工業大学
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] つねに再生・進化する酵素・バイオ触媒～ファインケミカル合成における活用2012
- Author(s)
  須貝威
- Organizer
  第2回CSJ化学フェスタ2012
- Place of Presentation
  東京工業大学大岡山キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] The complementary and integrated chemo-enzymatic processes for fine chemical syntheses2012
- Author(s)
  T. Sugai, Y. Yamashita, Y. Niitsu, M.Hamada, C. Hiraoka, T. Higashi, M. Shoji
- Organizer
  APCChE2012
- Place of Presentation
  Singapore
- Year and Date
  2012-02-23
- Invited
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] The Complementary and Integrated Chemo-enzymatic Processes for Fine Chemical Syntheses2012
- Author(s)
  T. Sugai, Y. Yamashita, Y. Niitsu, M. Hamada, C. Hiraoka, T. Higashi, and M. Shoji
- Organizer
  APCChE2012(招待講演)
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] Recognition of Remote Chiral Centers in the Course of Lipase-Catalyzed Resolution and Its Application to Both Enantiomers of TBMB Acid (Invited Lecture)2010
- Author(s)
  T.Sugai
- Organizer
  BIT's Inaugural Symposium on Enzymes & Biocatalysis
- Place of Presentation
  Shanghai
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] Regio- and stereoselective lipase-catalyzed reactions on sugars and carbasugars (Invited Lecture)2010
- Author(s)
  M.Hamada, Y.Ueda, N.Chishima, J.Calveras, T.Higashi, M.Shoji, T.Sugai
- Organizer
  The International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] Regio- and Stereoselective Lipase-catalyzed Reactions on Sugars and Carbasugars2010
- Author(s)
  M.Hamada, Y.Ueda, N.Chishima, J.Calveras, T.Higashi, M.Shoji, T.Sugai
- Organizer
  The International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] 微生物酵素を用いた不斉中心導入に基づくスタチン類の合成研究2009
- Author(s)
  坂本真希, 濱田学, 東利則, 庄司満, 須貝威
- Organizer
  第13回生体触媒化学シンポジウム
- Place of Presentation
  香川県(香川大学)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] 枯草菌エポキシヒドロラーゼの基質特異性解明について2009
- Author(s)
  清水賢一, 坂本真希, 濱田学, 東利則, 庄司満, 須貝威
- Organizer
  第13回生体触媒化学シンポジウム
- Place of Presentation
  香川県(香川大学)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] 加水分解酵東を用いた2, 2-ジ置換シアノ酢酸エステル類の速度論的光学分割2008
- Author(s)
  辰巳裕紀, 濱田学, 東利則, 須貝威
- Organizer
  第12回生体触媒化学シンポジウム
- Place of Presentation
  船橋市(東邦大学)
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] 多様な微生物起源に由来するエポキシドヒドロラーゼの基質特異性の比較2008
- Author(s)
  坂本真希, 濱田学, 藤野彩, 東利則, 須貝威
- Organizer
  第12回生体触媒化学シンポジウム
- Place of Presentation
  船橋市(東邦大学)
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] 含フッ東芳香族化合物の不斉還元・速度論的光学分割に関する検討2008
- Author(s)
  阿部智香, 岩永裕作, 東利則, 中村薫, 須貝威
- Organizer
  第12回生体触媒化学シンポジウム
- Place of Presentation
  船橋市(東邦大学)
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20580114
[Presentation] Complementary and Integrated Use of Lipase-catalyzed Reactions with Chemical Processes in Organic Synthesis2007
- Author(s)
  T.Sugai, M.Kurokawa, Y.Futamura, T.Takanami
- Organizer
  8th International Symposium on Biocatalysis and Biotransformations
- Place of Presentation
  Oviedo,Spain
- Year and Date
  2007-07-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Presentation] Complementary and Integrated Use of Lipase-catalyzed Reactions with Chemical Processes in Organic Synthesis2007
- Author(s)
  T., Sugai, M., Kurokawa, Y., Futamura, T., Takanami
- Organizer
  8th International Symposium on Biocatalysis and Biotransformations
- Place of Presentation
  Oviedo, Spain
- Year and Date
  2007-07-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580106
[Presentation] Complementary and Integrated Use of Lipase-catalyzed Reactions with Chemical Processes in Organic Synthesis2007
- Author(s)
  T. Sugai, M.Kurokawa, Y.Futamura, T.Takanami
- Organizer
  8th International Symposium on Biocatalysis and Biotransformations
- Place of Presentation
  Oviedo, Spani
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-18580106
[Presentation] トリアセチルD-グルカールから出発する4-O-メチル-ManNAcの合成研究
- Author(s)
  岡崎隼人、花屋賢悟、庄司　満、羽田紀康、須貝　威
- Organizer
  第32 回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-23580152
[Presentation] β-選択的 Ferrier反応を鍵段階とする、L-グルコースの合成研究
- Author(s)
  岡崎隼人、植田裕二、大場茂、羽田紀康、花屋賢悟、庄司満、須貝威
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23580152

1. UMEZAWA Kazuo (70114402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. BANNO Kouji (70265875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Hattori Yutaka (20189575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MORI Kenji (20011843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KUWAHARA Shigefumi (30170145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. EBATA Takashi (30160378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KITAHARA Takeshi (40087573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松本隆司 (70212222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木啓介 (90162940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 太田博道 (30152151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 柳川弘志 (40327672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 木内文之 (60161402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山田健人 (60230463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Sugai Takeshi 須貝 威

SUGAI Takeshi 須貝 威

須貝 威 スガイ タケシ

Research Projects

Research Products

Co-Researchers

Synthetic Studies of Bioactive Substances Based on Site- and Stereoselective ReactionsPrincipal Investigator

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Screening of NF-kappa B inhibitors having new core structure and application to aggressive cancer treatment

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Efficient organic synthesis utilizing microbial enzyme catalystsPrincipal Investigator

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Drug discovery based on novel concept for overcoming high-risk myeloma which is still intractable despite of recent progress in the treatment

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Design and synthesis of highly efficient substrate compatible to chemo-enzymatic synthesisPrincipal Investigator

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Fine chemical production by complementary use of microbial catalysts and organic synthesisPrincipal Investigator

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Molecular design and synthesis of soluble NF-κB inhibitor and suppression of ovarian carcinoma

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Screeing of novel microbial- and enzyme catalysts for expeditious chemical synthesis of useful substancesPrincipal Investigator

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Chemo-enzymatic Synthesis of Biologically Active Compounds based on Biocatalysts and BioresourcesPrincipal Investigator

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Development of Microbial Enzymatic Catalysts towards the Chemo-Enzymatic Synthesis of Bioactive SubstancesPrincipal Investigator

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Organic synthesis and Production based on Bioresources and BiocatalysisPrincipal Investigator

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複雑な天然物合成の基盤となる生化学的変換反応の捜索Principal Investigator

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生化学的官能基変換反応の開発と天然物合成への応用Principal Investigator

Principal Investigator

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Sugai Takeshi 須貝威

SUGAI Takeshi 須貝威

須貝威スガイタケシ

[Book] 酵素反応のスケールアップ-トラブル解決へのヒント-鳥澤保廣編、「創薬支援研究の展望」2008