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Morisaki Hiroshi  森崎 浩

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MORISAKI Hiroshi  森崎 浩

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Researcher Number 60182226
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2022: 慶應義塾大学, 医学部(信濃町), 教授
2016 – 2017: 慶應義塾大学, 医学部(信濃町), 教授
2012 – 2015: 慶應義塾大学, 医学部, 教授
2007 – 2011: Keio University, 医学部, 准教授
2003 – 2006: Keio University, School of Medicine, Associate professor, 医学部, 助教授 … More
1998 – 2003: 慶應義塾大学, 医学部, 講師
2001 – 2002: 慶應義塾大学, 医学部, 専任講師
1996: Keio University, School of Medicine, Assistant Professor, 医学部, 専任講師
1995: 慶應義塾大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Emergency medicine / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology
Except Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
敗血症 / 一酸化炭素 / 微小循環 / 接着分子 / ヘムオキシゲナーゼ / leukocyte / adhesion molecule / 白血球 / 腸内細菌 / 腸管壁防御機構 … More / 炎症性サイトカイン / 一酸化窒素 / 吸入麻酔 / 血管内皮細胞 / 血小板 / 機能的MRI / バイオマーカー / 術後遷延痛 / 変形性膝関節症 / 鎮痛 / 中枢性感作 / ミクログリア / fractalkine / 中枢性炎症 / 慢性痛 / 術後痛遷延化 / mmRNAトランスフェクション / 骨格筋 / カルシウムイメージング / 麻酔薬 / Neurogenin2 / 興奮性神経細胞 / iPS細胞 / 悪性高熱症 / Carbon monoxide / Nitric oxide / Gut barrier function / Hemoglobin / Microcirculation / Transfusion / Sepsis / 内毒素血症 / ヘモグロビン / 輸血 / carbon monoxide / heme oxygenase / endothelial cell / platelet / 白血病 / 吸入麻酔薬 / microcirculation / halothane / sevoflurane / endothelium / 好中球 / ハロセン / セボフルラン / 内皮細胞 / 腸管免疫機構 / カテコラミン / infection / bacteria / lipocalin-2 / 静菌効果 / NGAL / 感染症 / サイトカイン / 腸内細菌叢 / regulatory T cell / Th17 / Th2 / Th1 / リンパ球サブセット / 腸管関連リンパ組織 / 高血糖 / bacterial translocation / 生存率 / βブロッカー / TNF-α / 心機能障害 / LPS / ラット / 順行性摘出灌流心標本 / デクスメデトミジン / α2アゴニスト / 心筋保護 / 心筋障害 … More
Except Principal Investigator
心機能 / 敗血症 / nicaraven / サイトカイン / Kupffer cells / carbon monoxide / bilirubin / nitric oxide / microcirculation / Hemoglobin / Oxygen carrier / heme oxygenase / cytokine / free radical scavenger / cardiac function / sepsis / Lipopolysaccharide / フリーラジカル捕捉剤 / K-ATP channel / Cardiac Function / Sepsis / nicorandil / アポトーシス / Working heart / 死亡率 / Nicorandil / 肝臓 / シトクロームP450 / ヘムオキシゲナーゼ / 酸素 / 一酸化炭素 / リポソーム / hme oxygenase / ビリルビン / バイオイメージング / ヘモグロビン / 微小循環 / CO / NO / ラット敗血症モデル / oxytocin / オキシトシン Less
  • Research Projects

    (15 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (13 People)
  •  Exploration of predictive markers and establishment of preventative and therapeutic measures for chronic postsurgical pain targeting central sensitization mechanismsPrincipal Investigator

    • Principal Investigator
      Morisaki Hiroshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Keio University
  •  In vitro disease modeling of malignant hyperthermia using patient-derived iPS cellsPrincipal Investigator

    • Principal Investigator
      MORISAKI HIROSHI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology
    • Research Institution
      Keio University
  •  Effects of catecholamine on gut immune systems.Principal Investigator

    • Principal Investigator
      MORISAKI Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  Bacteriostatic effects of neutrophil gelatinase-associated lipocalin against clinically identified bacteriaPrincipal Investigator

    • Principal Investigator
      MORISAKI HIROSHI
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  Hyperglycemia-induced alterations of gut microflora and therapeutic strategy in a critically ill modelPrincipal Investigator

    • Principal Investigator
      MORISAKI Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  βブロッカーは敗血症患者の救命率を高める-擬似ラットモデルでの検討Principal Investigator

    • Principal Investigator
      森崎 浩
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  Effects of oxytocin on cardiovascular function in sepsis

    • Principal Investigator
      SERITA Ryohei
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  アルファ受容体刺激は敗血症心筋を護るPrincipal Investigator

    • Principal Investigator
      森崎 浩
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  Effect of free radical scavenger on cardiovascular system in sepsis

    • Principal Investigator
      SERITA Ryohei
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  Optimal hemoglobin level in gut barrier function of sepsis-Roles of heme oxygenase-1Principal Investigator

    • Principal Investigator
      MORISAKI Hiroshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  Effect of nicorandil on cardiac function in sepsis

    • Principal Investigator
      SERITA Ryohei
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      KEIO UNIVERSITY
  •  Development of artificial oxygen carriers under consideration of microvascular homeostasis

    • Principal Investigator
      SUEMATSU Makoto
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  麻酔薬による臓器微小循環血小板接着反応の生体内解析Principal Investigator

    • Principal Investigator
      森崎 浩
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  In vivo analyses of anesthesia-elicited endothelial cell adhesion and heme oxygenase-1Principal Investigator

    • Principal Investigator
      MORISKAI Hiroshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University
  •  Microvascular endothelial function and leukocyte adhesion mechanisms during inhalational anesthesiaPrincipal Investigator

    • Principal Investigator
      MORISAKI Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Keio University

All 2022 2020 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Objective and Quantitative Evaluation of Spontaneous Pain-Like Behaviors Using Dynamic Weight-Bearing System in Mouse Models of Postsurgical Pain2022

    • Author(s)
      Fanglin Lu, Jungo Kato, Tomoko Toramaru, Megumi Sugai, Mengting Zhang, Hiroshi Morisaki
    • Journal Title

      Journal of Pain Research

      Volume: 15 Pages: 1601-1612

    • DOI

      10.2147/jpr.s359220

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09206
  • [Journal Article] Beta-1 blocker improves survival of septic rats through preservation of gut barrier function2011

    • Author(s)
      Katsuya Mori, Hiroshi Morisaki, Satoshi Yajima Takeshi Suzuki, Akiko Ishikawa, Norihito Nakamura, Yasushi Innami, Junzo Takeda.
    • Journal Title

      Intensive Care Med

      Volume: Vol.37 Pages: 1849-1856

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Journal Article] 敗血症における心機能障害~心筋保護とβ遮断薬の可能性~2011

    • Author(s)
      鈴木武志、芹田良平、森崎浩
    • Journal Title

      日集中医誌

      Volume: 18巻 Pages: 193-200

    • NAID

      130004514316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Journal Article] 硬膜外麻酔の抗炎症作用2010

    • Author(s)
      長田大雅、森力哉、森崎浩
    • Journal Title

      臨床麻酔

      Volume: 34巻 Pages: 1856-1863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Journal Article] 膜外麻酔・鎮痛と消化管粘膜保護2010

    • Author(s)
      森崎浩
    • Journal Title

      日臨麻会誌

      Volume: 30巻 Pages: 106-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Journal Article] Tumor necrosis factor-α mediates hyperglycemia augmented gut barrier dysfunction in endotoxemia2009

    • Author(s)
      Yajima Satoshi, Morisaki Hiroshi, Serita, Ryohei, Suzuki Takeshi, Katori Nobuyuki, Asahara Takashi Nomoto Koji, Kobayashi Fujio, Ishizaka Akitoshi, Takeda Junzo
    • Journal Title

      Crit Care Med

      Volume: Vol.37 Pages: 1024-1030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] 人工膝関節置換術術後の遷延痛および疼痛関連障害度と術前の心理社会的因子および中枢性炎症との関連2020

    • Author(s)
      村瀬玲子、小杉志都子、加藤純悟、西村大輔、伊原奈帆、星野麗子、本田あやか、森崎浩
    • Organizer
      日本ペインクリニック学会 第54回学術集会
    • Data Source
      KAKENHI-PROJECT-20K09206
  • [Presentation] PERSISTENT HYPERGLYCEMIA UP-REGULATES INFLAMMATORY CYTOKINES IN MESENTERIC LYMPH NODES IN ENDOTOXEMIC RATS2011

    • Author(s)
      Mori K, Morisaki H, et al
    • Organizer
      American Society of Anesthesiologists Annual Meeting 2011
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] Per sistent hyperglycemian up-regula tes inflammatory cytokines in me senteric lymoh nodes in endotoxe mic rats2011

    • Author(s)
      Katsuya Mori, Hiroshi Morisaki, Toru Igarashi, Junzo Takeda
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] Hyperglycemia per se deteriorates gut barrier function in rats2010

    • Author(s)
      Katsuya Mori, Hiroshi Morisaki, Satoshi Yajima, Norihito Nakamura, Junzo Takeda
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] Hyperglycemia per se deteriorates gut barrier function in rats2010

    • Author(s)
      Mori K, Morisaki H, et al
    • Organizer
      American Society of Anesthesiologists Annual Meeting 2011
    • Place of Presentation
      サンディエゴ(米国)
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] Beta-blocker therapy minimizes gut mucosal injury and local inflammatory response in peritonitis-evoked septic rats2010

    • Author(s)
      Katsuya Mori, Hiroshi Morisaki, Takeshi Suzuki, Yasushi Innami, Junzo Takeda
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-21390484
  • [Presentation] Beta-blocker, esmolol, infusion improves survival of septic rats2009

    • Author(s)
      森崎浩
    • Organizer
      米国麻酔学会
    • Place of Presentation
      ニューオリンズ, USA
    • Year and Date
      2009-10-17
    • Data Source
      KAKENHI-PROJECT-20659283
  • [Presentation] Beta-blocker, esmolol, infusion improves survival of septic rats2009

    • Author(s)
      Hiroshi Morisaki, Katsuya Mori, Satoshi Yajima, Takeshi Suzuki, Junzo Takeda
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-21390484
  • 1.  SUEMATSU Makoto (00206385)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  SERITA Ryohei (50245594)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  SUZUKI Takeshi (80327600)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  矢島 聡 (10348766)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  AI Kimiaki (30265847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YAMADA Takashige (20348767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKEOKA Shinji (20222094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KOTAKE Yoshifumi (70195733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORITA Yoshihisa (10276983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OKANO Hideyuki (60160694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  小杉 志都子 (00317249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  加藤 純悟 (40465018)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  寅丸 智子 (70594612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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