HORI Yuuichi 堀雄一

Researcher Number	60190229
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2013: 獨協医科大学, 医学部, 教授 1997 – 2002: 獨協医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator 神経・脳内生理学 / Neurophysiology and muscle physiology Except Principal Investigator Anesthesiology/Resuscitation studies
Keywords	Principal Investigator エンケファリン / GFP / Enkephalin / パッチクランプ記録 / Biolistic Gene Gun / Organotypic Slice Culture / Patch-Clamp Recording / Spinal Dorsal Horn Neurons / Preproenkephalin Promoter / エンケファリンプロモーター … More / 脊髄スライスカルチャー / エンケファリンプロモーター / 脊髄切片培養 / 脊髄後角ニューロン / エンケファリンプロモータ / 遺伝子銃 / Polymerase Chain Reaction / Reverse Transcripcion / Superficial dorsal horn, / Path Clamp Methods / Single cell RT-PCR / 単一細胞RT-PCR法 / パッチクランプ法 / ポリメラーゼ連鎖反応 / 逆転写反応 / 脊髄後角表層 / パッチクランプ記録法 / セロトニン受容体 / NMDA受容体サブユニット / 興奮性シナプス後電流 / 単一細胞遺伝子発現解析 / 脊髄後角表層ニューロン / 脊髄痛覚神経回路 / BKチャネル / NMDA受容体 … More Except Principal Investigator グルタミン酸トランスポーター / Na^+-Ca^<2+>exchanger / ホールセル・パッチクランプ法 / 神経細胞 / 脳虚血 / 蛍光色素法 / 細胞膜電位 / 細胞内Ca^<2+>濃度 Less

Characterization of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic micePrincipal Investigator
- Principal Investigator
  
  HORI Yuuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Dokkyo Medical University
Visualization of enkephalin-containing neurons using preproenkephalin-promoter GFP vectorPrincipal Investigator
- Principal Investigator
  
  HORI Yuuichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Dokkyo Medical University
脳虚血細胞内カルシウムイオン濃度上昇におけるメカニズムの検討と麻酔薬の抑制効果
- Principal Investigator
  
  山口重樹
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Dokkyo Medical University
Identification and characterization of enkephalinergic neurons in spinal cord dorsal horn: Single cell RT-PCR analysisPrincipal Investigator
- Principal Investigator
  
  HORI Yuuichi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Dokkyo University School of Medicine

All 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: further characterization of presynaptic mechanisms2014
- Author(s)
  Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y
- Journal Title
  
  Neuroscience Letters
  
  Volume: 558 Pages: 186-191
- DOI
  10.1016/j.neulet.2013.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468, KAKENHI-PROJECT-24300142
[Journal Article] Effects of pregabalin on D-serine content and NMDA receptor-mediated synaptic transmission in the mouse spinal cord2014
- Author(s)
  Matsuzawa R, Takasusuki T, Maekawa M, Yamaguchi S, Hori Y
- Journal Title
  
  FASEB JJourrnall
  
  Volume: 28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Effects of pregabalin on D-serine content and NMDA receptor- mediated synaptic transmission in the mouse spinal cord2014
- Author(s)
  Matsuzawa R, Takasusuki T, Maekawa M, Yamaguchi S, Hori Y
- Journal Title
  
  FASEB J
  
  Volume: 28
- URL
  http://www.fasebj.org/content/28/1_Supplement/1129.9.abstract?sid=4050e95d-dfa4-488c-9600-cfb6a2587ba6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Differential expression of NMDA receptors in serotonergic and/or GABAergic　neurons in the midbrain periaqueductal gray of the mouse2012
- Author(s)
  Terashima T, Shirakawa K, Maekawa M, Furukawa N, Yamaguchi S, Hori Y
- Journal Title
  
  Neurosci Letters
  
  Volume: 528 Issue: 1 Pages: 55-60
- DOI
  10.1016/j.neulet.2012.08.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic beta-cells2012
- Author(s)
  Miura Y, Hori Y, Kimura S, Hachiya H, Sakurai Y, Inoue K, Sawada T, Kubota K
- Journal Title
  
  Toxicology
  
  Volume: 299 Issue: 2-3 Pages: 165-171
- DOI
  10.1016/j.tox.2012.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Functional roles of endogenous D-serine in pain-induced ultrasonic vocalization2012
- Author(s)
  Tsuzuki H, Maekawa M, Konno R, Hori Y
- Journal Title
  
  Neuroreport
  
  Volume: 23 Issue: 16 Pages: 937-941
- DOI
  10.1097/wnr.0b013e3283595726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Functional roles of endogenous D-serine in the chronic pain-induced plasticity of NMDAR-mediated synaptic transmission in the central amygdala of mice2012
- Author(s)
  Maekawa M, Wakamatsu S, Huse N, Konno R, Hori Y
- Journal Title
  
  Neuroscience Letters
  
  Volume: 520 Issue: 1 Pages: 57-61
- DOI
  10.1016/j.neulet.2012.05.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Journal Article] Physiological properties of enkephalin- containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice2011
- Author(s)
  Fukushima T, Tsuda M, Kofuji T, Hori Y
- Journal Title
  
  BMC Neuroscience
  
  Volume: 12 Issue: 1 Pages: 36-36
- DOI
  10.1186/1471-2202-12-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] 実験的熱性けいれん後のマウス海馬CA1におけるSyntaxin 1A発現の減少2014
- Author(s)
  金子堅太郎、加藤永子、福島央之、前川正夫、堀　雄一
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] シンタキシン1Aノックアウトマウスのセロトニン神経支配と慢性疼痛による情動行動の変化2014
- Author(s)
  前川正夫、堀　雄一
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] シンタキシン 1A ノックアウトマウスのセロトニン神経支配と慢性疼痛による情動行動の変化2014
- Author(s)
  前川正夫, 堀雄一
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] 実験的熱性けいれん後のマウス海馬 CA1 における Syntaxin 1A 発現の減少2014
- Author(s)
  金子賢太郎, 加藤永子, 福島央之, 前川正夫, 堀雄一
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Inhibitory effect of pregabalin on excitatory synaptic transmission in the spinal dorsal horn after nerve injury2013
- Author(s)
  Matsuzawa R, Yamaguchi S, Takasusuki T, Ohtsubo T, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Inhibitory effect of pregabalin on excitatory synaptic transmission in the spinal dorsal horn after nerve injury2013
- Author(s)
  Matsuzawa R, Yamaguchi S, Takasusuki T, Ohtsubo T, Hori Y
- Organizer
  アメリカ神経科学学会
- Place of Presentation
  アメリカ　サンディエゴ
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Intrathecal administration of botulinum toxin A presynaptically inhibits excitatory synaptic transmission in the spinal dorsal horn2013
- Author(s)
  Nemoto K, Matsuzawa R, Fukushima T, Takasusuki S, Yamaguchi S, Hori Y
- Organizer
  アメリカ神経科学学会
- Place of Presentation
  アメリカ　サンディエゴ
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Intrathecal administration of botulinum toxin A presynaptically inhibits excitatory synaptic transmission in the spinal dorsal horn2013
- Author(s)
  Nemoto K, Matsuzawa R, Fukushima T, Takasusuki T, Yamaguchi S, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Visualization of serotonergic neurons in the Nucleus Raphe Magnus using BAC transgenic mice2012
- Author(s)
  T. FUKUSHIMA, K. YUGE, Y. HORI
- Organizer
  北米神経科学学会 Neuroscience 2012
- Place of Presentation
  Ernest N. Memorial Convention Center (米国、ニューオリンズ）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] BAC トランスジェニックマウスにおいて可視化された大縫線核のセロトニン作動性神経の生理学的機能解析2012
- Author(s)
  福島央之, 弓削和哉, 津田雅之, 堀雄一
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Expression patterns of glial marker proteins in the spinal cord in mouse models of cancer pain2012
- Author(s)
  S. KOBAYASHI, K. YUGE, T. FUKUSHIMA, S. TANAKA, M. NOZAKI, Y. HORI
- Organizer
  北米神経科学学会 Neuroscience 2012
- Place of Presentation
  Ernest N. Memorial Convention Center (米国、ニューオリンズ）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] The effects of HPC1/Syntaxin 1A gene knockout on the general anesthetic actions of sevoflurane2012
- Author(s)
  Kokubu S, Matsuzawa R, Nemoto K, Fukushima T, Yamaguchi S, Maekawa M, Fujiwara T, Akagawa K, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Expression patterns of glial marker proteins in the spinal cord in mouse models of cancer pain2012
- Author(s)
  Kobayashi S, Yuge K, Fukushima T, Tanaka S, Nozaki M, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Intrathecal administration of botulinum toxin A: Antiallodynic action and inhibition of excitatory synaptic transmission in the spinal dorsal horn2012
- Author(s)
  K. NEMOTO, S. YAMAGUCHI, R. MATSUZAWA, T. TAKASUSUKI, T. TERASHIMA, T. FUKUSHIMA, T. OTSUBO, Y. HORI
- Organizer
  北米神経科学学会 Neuroscience 2012
- Place of Presentation
  Ernest N. Memorial Convention Center (米国、ニューオリンズ）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Visualization of serotonergic neurons in the Nucleus Raphe Magnus using BAC transgenic mice2012
- Author(s)
  Fukushima T, Yuge K, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Intrathecal administration of botulinum toxin A : Antiallodynic action and inhibition of excitatory synaptic transmission in the spinal dorsal horn2012
- Author(s)
  Nemoto K, Yamaguchi S, Matsuzawa T, Takasusuki T, Terashima T, Fukushima T, Ohtsubo T, Hori Y
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] The effects of HPC1/Syntaxin 1A gene knockout on the general anesthetic actions of sevoflurane2012
- Author(s)
  S. KOKUBU, R. MATSUZAWA, K. NEMOTO, T. FUKUSHIMA, S. YAMAGUCH, M. MAEKAWA, T. FUJIWARA, K. AKAGAWA, Y. HORI
- Organizer
  北米神経科学学会 Neuroscience 2012
- Place of Presentation
  Ernest N. Memorial Convention Center (米国、ニューオリンズ）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] 神経因性疼痛行動とセリンラセーマーゼの脊髄における分布2012
- Author(s)
  弓削主哉、福島央之、田中志歩、金野柳一、堀雄一
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] BACトランスジェニックマウスにおいて可視化された大縫線核のセロトニン作動性神経の生理学的機能解析2012
- Author(s)
  福島央之、弓削和哉、津田雅之、堀雄一
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] 神経因性疼痛行動とセリンラセマーゼの脊髄における分布2012
- Author(s)
  弓削和哉, 福島央之, 田中志歩, 金野柳一, 堀雄一
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Sciatic nerve ligation induces up-regulation of functional 5-HT3 receptor on glutamatergic excitatory neurons in the mouse spinal superficial dorsal horn2011
- Author(s)
  福島央之, 堀雄一
- Organizer
  日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23500468
[Presentation] Differential effects of peripheral nerve injury on serotonergic and non-serotonergic neurons in mouse periaqueductal gray matter2011
- Author(s)
  Shirakawa K, Yamaguchi S, Kokubu S, Takasusuki M, Maekawa M, Kitajima T, Hori Y
- Organizer
  Soiety for Neuroscience Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23500468

1. 山口重樹 (50306198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 北島敏光 (50137717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HORI Yuuichi 堀 雄一

Research Projects

Research Products

Co-Researchers

Characterization of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualization of enkephalin-containing neurons using preproenkephalin-promoter GFP vectorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳虚血細胞内カルシウムイオン濃度上昇におけるメカニズムの検討と麻酔薬の抑制効果

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and characterization of enkephalinergic neurons in spinal cord dorsal horn: Single cell RT-PCR analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: further characterization of presynaptic mechanisms2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of pregabalin on D-serine content and NMDA receptor-mediated synaptic transmission in the mouse spinal cord2014

Author(s)

Journal Title

Data Source

[Journal Article] Effects of pregabalin on D-serine content and NMDA receptor- mediated synaptic transmission in the mouse spinal cord2014

Author(s)

Journal Title

URL

Data Source

[Journal Article] Differential expression of NMDA receptors in serotonergic and/or GABAergic neurons in the midbrain periaqueductal gray of the mouse2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic beta-cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional roles of endogenous D-serine in pain-induced ultrasonic vocalization2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional roles of endogenous D-serine in the chronic pain-induced plasticity of NMDAR-mediated synaptic transmission in the central amygdala of mice2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological properties of enkephalin- containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 実験的熱性けいれん後のマウス海馬CA1におけるSyntaxin 1A発現の減少2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] シンタキシン1Aノックアウトマウスのセロトニン神経支配と慢性疼痛による情動行動の変化2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] シンタキシン 1A ノックアウトマウスのセロトニン神経支配と慢性疼痛による情動行動の変化2014

Author(s)

Organizer

HORI Yuuichi 堀雄一

[Journal Article] Differential expression of NMDA receptors in serotonergic and/or GABAergic　neurons in the midbrain periaqueductal gray of the mouse2012