Yokoi Norihiko 横井則彦

… Alternative Names

横井則彦ヨコイノリヒコ

YOKOI Norihiko 横井則彦

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Researcher Number	60191491
Other IDs
External Links
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 客員教授
Affiliation (based on the past Project Information) *help	2023: 京都府立医科大学, 医学(系)研究科(研究院), 客員教授 2020 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2011 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2015: 京都府立医科大学, 医学研究科, 准教授 2013: 京都府立医科大学, 医学研究科, 准教授 … More 2007 – 2010: Kyoto Prefectural University of Medicine, 医学研究科, 准教授 2003: Kyoto Prefectural University of Medicine, Ophthalmology, Associate Professor, 医学研究科, 助教授 2002: 京都府立医科大学, 医学部, 助教授 1999: Medicine, Ophthalmology, Associate Professor, 医学部, 助教授 1997 – 1998: 京都府立医科大学, 医学部, 講師 1994: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Ophthalmology
Keywords	Principal Investigator 界面化学 / ドライアイ / 涙液層破壊 / 涙液液層 / 涙液油層 / 角膜上皮 / 涙液層形成 / 涙液層破壊パターン / 涙液層 / ソフトコンタクトレンズ … More / LDH / major basic protein / マイボーム腺脂質 / レオロジー / 生理学 / 涙液 / 温度 / バリアー機能 / 非侵襲的涙液層検査 / ドライアイ病態生理 / 分泌型ムチン / 深層学習 / 油層伸展 / 涙液各層の相互作用 / ゴマ油 / MUC16 / 気泡法 / 接触角 / 蒸発亢進 / 涙液減少 / 水濡れ性低下 / 結膜弛緩症 / 水濡れ性 / 涙液層動態 / 安定性 / Soft Contact Lens / Tear Specular / Video-Meniscometry / Dry Eye / Artificial Chamber / Tear Dynamics / Environmental Condition / 湿度 / ビデオメニスフメトリー法 / 涙液スペキュラー / ビデオメニスコメトリー法 / 人工気候室 / 涙液動態 / 環境 / Ig E / epithelial barrier function / facial dermatitis / aqueous flare / atopic cataract / atopic dermatitis / 好酸球 / 網膜剥離 / MBP / 末梢血好酸球 / 白内障 / 総IgE値 / 血清LDH値 / 皮疹スコア / 皮疹面積 / 結膜上皮 / IgE / 上皮バリアー機能 / 顔面皮疹 / 前房フレア値 / アトピー性白内障 / アトピー性皮膚炎 / マイボーム腺機能不全 / トポグラフィー / 国際情報交換 / 光干渉 / 油層 / 角膜上皮細胞 / 機能的RNA / メチル化 / エピジェネティクス / miRNA / 細胞・組織 / 移植・再生医療 / 発生・分化 / 再生医療 / 移植 / 涙腺 / カドヘリン / カルシウムイオン / 角膜内皮 … More Except Principal Investigator ドライアイ / 過酸化脂質 / 細菌 / 脂質分析 / マイボーム腺機能不全 / 性ホルモン / マイボーム腺 / IL-1β / マウスドライアイモデル / 炎症性細胞浸潤 / 眼窩外涙腺摘出マウスドライアイモデル / 眼窩内涙腺 / 眼窩外涙腺 / ドライアイモデルマウス / caspase-1 / インフラマゾーム Less

涙液油層機能を維持する生理活性脂質の応用をめざした基礎研究と臨床基盤の確立Principal Investigator
- Principal Investigator
  
  横井則彦
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the mechanism for the formation and breakup of tear film based on lipid layer dynamics and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  YOKOI NORIHIKO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
The basic understanding of biological regulation on meibomian glands and ocular surface via sex steroid hormones
- Principal Investigator
  
  SUZUKI TOMO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Demonstration of the Molecular Mechanism of Meibomian Lipids on the Determination of Dynamic Characteristics of the Tear Film Lipid LayerPrincipal Investigator
- Principal Investigator
  
  Yokoi Norihiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
The contribution of inflammasome in the pathogenesis of dry eye
- Principal Investigator
  
  SHINOMIYA Katsuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
涙液油層の動態解析法の開発と涙液油層動態決定因子の探索的研究Principal Investigator
- Principal Investigator
  
  横井則彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Regeneration of lacrimal grand by the induction of highly-ordered acinus branchingPrincipal Investigator
- Principal Investigator
  
  YOKOI Norihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Basic study of the effects of environmental conditions on tear dynamics using an environmental chamberPrincipal Investigator
- Principal Investigator
  
  YOKOI Norihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of pathogenesis of ocular complications associated with atopic dermatitis and elucidation of factors predictive of their occurancePrincipal Investigator
- Principal Investigator
  
  YOKOI Norihiko
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
角膜上皮および内皮バリアー機能の調節機構に関する研究Principal Investigator
- Principal Investigator
  
  横井則彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] シェーグレン症候群の診断と治療マニュアル　改定第3版2018
- Author(s)
  横井則彦
- Total Pages
  235
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-16K11269
[Book] 1336専門家による私の治療 2017-18年度版2017
- Author(s)
  横井則彦
- Total Pages
  1734
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-16K11269
[Book] マイボーム腺機能不全（MGD）の診断と治療2016
- Author(s)
  横井則彦
- Total Pages
  12
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-16K11269
[Book] 角膜疾患　外来でこう診てこう治せ2015
- Author(s)
  横井則彦
- Total Pages
  340
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-25462728
[Book] 前眼部画像診断 A to Z2015
- Author(s)
  横井則彦
- Total Pages
  400
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-25462728
[Book] 一目でわかる眼疾患の見分け方2015
- Author(s)
  横井則彦
- Total Pages
  224
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-25462728
[Book] 前眼部の画像診断　専門医のための眼科診療クオリファイ2014
- Author(s)
  横井則彦
- Total Pages
  414
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25462728
[Book] Dry Eye Syndrome: Basic and Clinical Perspectives2013
- Author(s)
  Yokoi N
- Total Pages
  124
- Publisher
  Future Medicine Ltd
- Data Source
  KAKENHI-PROJECT-25462728
[Book] ドライアイ　スペシャリストへの道　専門医のための眼科診療クオリファイ2013
- Author(s)
  横井則彦
- Total Pages
  422
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25462728
[Book] 年齢とともにドライアイがひどくなると聞きました. 何か気をつけられることはありますか? 患者さんから浴びせられる眼科疾患100の質問2008
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Book] ドライアイで防腐剤抜きの目薬を使うようにいわれました. どこで手に入るのでしょうか? 患者さんから浴びせられる眼科疾患100の質問2008
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Book] ドライアイ. 眼科プラクティス18前眼部アトラスIII. 角膜7. 角膜上皮・表面2007
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Book] メニスコメトリ、インターフェロメトリ. 今日の眼疾患治療指針第2版2007
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Book] 涙液検査. 今日の眼疾患治療指針第2版2007
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Book] 眼科プラクティス18 前眼部アトラス (ドライアイの項担当)2007
- Author(s)
  横井則彦
- Total Pages
  6
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19592034
[Book] マイボメトリ、マイボグラフィ. 今日の眼疾患治療指針第2版
- Author(s)
  横井則彦
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Evaluation of Dry Eye with Videokeratographer Using a Newly-Developed Indicator2024
- Author(s)
  Kusada N, Yokoi N, Kato H, Furusawa Y, Sakai R, Sotozono C
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 252 Pages: 135-146
- DOI
  10.1016/j.ajo.2023.03.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Dry Eye Subtype Classification Using Videokeratography and Deep Learning2024
- Author(s)
  Yokoi N, Kusada N, Kato H, Furusawa Y, Sotozono C, Georgiev GAs
- Journal Title
  
  Diagnostics
  
  Volume: 14 Issue: 1 Pages: 52-52
- DOI
  10.3390/diagnostics14010052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Surface Chemistry Study of Normal and Diseased Human Meibum Films Prior to and after Supplementation with Tear Mimetic Eyedrop Formulation2024
- Author(s)
  Eftimov P, Yokoi N, Tsuji K, Takahashi K, Nishiyama M, Peev N, Koeva AS, Georgiev Gas
- Journal Title
  
  Applied Sciences
  
  Volume: 14 Issue: 8 Pages: 3390-3390
- DOI
  10.3390/app14083339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Association between Corneal Higher-Order Aberrations Evaluated with a Videokeratographer and Corneal Surface Abnormalities in Dry Eye2023
- Author(s)
  Kusada N, Yokoi N, Sotozono C
- Journal Title
  
  Diagnostics
  
  Volume: 13 Issue: 21 Pages: 3319-3319
- DOI
  10.3390/diagnostics13213319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Successful Detection of the Characteristics of Tear Film Breakup Appearing Immediately after Eye Opening by Videokeratography with a Newly-Developed Indicator2023
- Author(s)
  Norihiko Yokoi, Natsuki Kusada, Hiroaki Kato, Yuki Furusawa, Chie Sotozono, Georgi As. Georgiev
- Journal Title
  
  Diagnostics
  
  Volume: 13 Issue: 2 Pages: 240-240
- DOI
  10.3390/diagnostics13020240
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Langmuir Trough Study of the Interactions of Tear Mimetic Eyedrop Formulation with Human Meibum Films2022
- Author(s)
  Petar Eftimov, Norihiko Yokoi,Kazuhiro Tsuji, Nikola Peev Georgi As. Georgiev
- Journal Title
  
  Applied Sciences
  
  Volume: 12 Issue: 23 Pages: 12095-12095
- DOI
  10.3390/app122312095
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Surface chemistry study of the interactions of sesame oil with meibomian films.2022
- Author(s)
  Eftimov P, Yokoi　N, Georgiev GAs.
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 2 Pages: 464-464
- DOI
  10.3390/molecules27020464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Investigation of the relationship between ocular sarcoidosis and dry eye.2022
- Author(s)
  Aoki T, Yokoi N, Nagata K, Deguchi H, Sekiyama Y, Sotozono C.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 3469-3469
- DOI
  10.1038/s41598-022-07435-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09794, KAKENHI-PROJECT-19K09972
[Journal Article] Adherence to Eye Drops Usage in Dry Eye Patients and Reasons for Non-Compliance: A Web-Based Survey.2022
- Author(s)
  Uchino M, Yokoi N, Shimazaki J, Hori Y, Tsubota K
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 2 Pages: 367-367
- DOI
  10.3390/jcm11020367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09961, KAKENHI-PROJECT-20K09794
[Journal Article] Evaluation of Eye-Pain Severity between Dry-Eye Subtypes.2021
- Author(s)
  Yoshikawa Y, Yokoi N, Kato H, Sakai R, Komuro A, Sonomura Y, Ikeda T, Sotozono C.
- Journal Title
  
  Diagnostics (Basel).
  
  Volume: - Issue: 2 Pages: 166-166
- DOI
  10.3390/diagnostics11020166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] The relationship between subjective symptoms and quality of life in conjunctivochalasis patients.2021
- Author(s)
  Komuro A, Yokoi N, Kato H, Sonomura Y, Sotozono C, Kinoshita S.
- Journal Title
  
  Diagnostics (Basel)
  
  Volume: 11 Issue: 2 Pages: 179-179
- DOI
  10.3390/diagnostics11020179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Clinical Implication of Patchy Pattern Corneal Staining in Dry Eye Disease.2021
- Author(s)
  Komai S, Yokoi N, Kato H, Komuro A, Sonomura Y, Kinoshita S, Sotozono C.
- Journal Title
  
  Diagnostics (Basel).
  
  Volume: - Issue: 2 Pages: 232-232
- DOI
  10.3390/diagnostics11020232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Interactions of Meibum and Tears with Mucomimetic Polymers: A Hint towards the Interplay between the Layers of the Tear Film2021
- Author(s)
  Eftimov P, Yokoi N, Melo AM, Daull P, Georgiev GA.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: - Issue: 5 Pages: 2747-2747
- DOI
  10.3390/ijms22052747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Journal Article] Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels2019
- Author(s)
  Eftimov P, Yokoi N, Peev N, Georgiev GA
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Issue: 6 Pages: 1-13
- DOI
  10.3390/ijms20061313
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Tear-film-oriented diagnosis for dry eye2019
- Author(s)
  Yokoi N, Georgiev GA
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 63 Issue: 2 Pages: 127-136
- DOI
  10.1007/s10384-018-00645-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Tear Film-Oriented Diagnosis and Tear Film-Oriented Therapy for Dry Eye Based on Tear Film Dynamics2018
- Author(s)
  Yokoi N, Georgiev GA
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 59 Issue: 14 Pages: DES13-DES13
- DOI
  10.1167/iovs.17-23700
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Structure-function relationship of tear film lipid layer: A contemporary perspective2017
- Author(s)
  Georgiev GA, Eftimov P, Yokoi N
- Journal Title
  
  Exp Eye Res
  
  Volume: 163 Pages: 17-28
- DOI
  10.1016/j.exer.2017.03.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Surface Chemistry Interactions of Cationorm with Films by Human Meibum and Tear Film Compounds2017
- Author(s)
  Georgiev GA, Yokoi N, Nencheva Y, Peev N, Daull P
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 7 Pages: 1-17
- DOI
  10.3390/ijms18071558
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Asia Dry Eye Society. New perspectives on dry eye definition and diagnosis: A consensus report by the Asia Dry Eye Society2017
- Author(s)
  Tsubota K, Yokoi N, Shimazaki J, Watanabe H, Dogru M, Yamada M, Kinoshita S, Kim HM, Tchah HW, Hyon JY, Yoon KC, Seo KY, Sun X, Chen W, Liang L, Li M, Liu Z
- Journal Title
  
  Ocul Surf
  
  Volume: 15 Issue: 1 Pages: 65-76
- DOI
  10.1016/j.jtos.2016.09.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] TFOS DEWS II pathophysiology report.2017
- Author(s)
  Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V, Uchino Y, Yokoi N, Zoukhri D, Sullivan DA
- Journal Title
  
  Ocul Surf
  
  Volume: 15 Issue: 3 Pages: 438-510
- DOI
  10.1016/j.jtos.2017.05.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] ドライアイ診療のための涙液層のブレイクアップ分類最前線2017
- Author(s)
  横井則彦
- Journal Title
  
  あたらしい眼科
  
  Volume: 34 Pages: 315-322
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] Classification of Fluorescein Breakup Patterns: A Novel Method of Differential Diagnosis for Dry Eye.2017
- Author(s)
  Yokoi N, Georgiev GA, Kato H, Komuro A, Sonomura Y, Sotozono C, Tsubota K, Kinoshita S
- Journal Title
  
  Am J Ophthalmol
  
  Volume: 180 Pages: 72-85
- DOI
  10.1016/j.ajo.2017.05.022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Journal Article] 涙液層動態と画像診断　現状と課題2015
- Author(s)
  横井則彦、牛　夢茜
- Journal Title
  
  日本の眼科
  
  Volume: 86 Pages: 456-461
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Importance of tear film instability in dry eye disease in office workers using visual display terminals: The Osaka study2015
- Author(s)
  Yokoi N, Uchino M, Uchino Y, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Tsubota K, Kinoshita S.
- Journal Title
  
  Am J Ophthalmol.
  
  Volume: 159 Issue: 4 Pages: 748-754
- DOI
  10.1016/j.ajo.2014.12.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Surface properties of squalene/meibum films and NMR confirmation of squalene in tears.2015
- Author(s)
  Ivanova S, Tonchev V, Yokoi N, Yappert MC, Borchman D, Georgiev GA
- Journal Title
  
  Int J Mol Sci
  
  Volume: 16 Issue: 9 Pages: 21813-21831
- DOI
  10.3390/ijms160921813
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Three percent diquafosol ophthalmic solution as an additional therapy to existing artificial tears with steroids for dry-eye patients with Sjögren’s syndrome2015
- Author(s)
  Yokoi N, Sonomura Y, Kato H, Komuro A
- Journal Title
  
  Eye
  
  Volume: 29 Issue: 9 Pages: 1204-1212
- DOI
  10.1038/eye.2015.125
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] 涙液からみたコンタクトレンズ2015
- Author(s)
  横井則彦
- Journal Title
  
  日コレ誌
  
  Volume: 57 Pages: 222-235
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] ドライアイ治療のフロンティアTFOT(Tear Film Oriented Therapy)2014
- Author(s)
  横井則彦
- Journal Title
  
  Medical Science Digest
  
  Volume: 40 Pages: 112-115
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] The precorneal tear film as a fluid shell: the effect of blinking and saccades on tear film distribution and dynamics2014
- Author(s)
  Yokoi N, Bron AJ, Georgiev GA
- Journal Title
  
  Ocul Surf
  
  Volume: 12 Issue: 4 Pages: 252-266
- DOI
  10.1016/j.jtos.2014.01.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Facilitation of Tear Fluid Secretion by 3% Diquafosol Ophthalmic Solution in Normal Human Eyes2014
- Author(s)
  Yokoi N, Kato H, Kinoshita S
- Journal Title
  
  Am J Ophthalmol
  
  Volume: 157 Issue: 1 Pages: 85-92
- DOI
  10.1016/j.ajo.2013.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Surface relaxations as a tool to distinguish the dynamic interfacial properties of films formed by normal and diseased meibomian lipids2014
- Author(s)
  Georgiev GA, Yokoi N, Ivanova S, Tonchev V, Nencheva Y, Krastev R
- Journal Title
  
  Soft Matter
  
  Volume: 10 Issue: 30 Pages: 5579-5588
- DOI
  10.1039/c4sm00758a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Dry eye disease and work productivity loss in visual display users: the Osaka study2013
- Author(s)
  Uchino M, Uchino Y, Dogru M, Kawashima M, Yokoi N, Komuro A, Sonomura Y, Kato H, Kinoshita S, Schaumberg DA, Tsubota K
- Journal Title
  
  Am J Ophthalmol
  
  Volume: 157 Issue: 2 Pages: 294-300
- DOI
  10.1016/j.ajo.2013.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Immunohistochemical analysis of inflammatory limbal conjunctiva adjacent to Mooren’s ulcer2013
- Author(s)
  篠宮克彦、上田真由美、外園千恵、稲富勉、横井則彦、小泉範子、木下茂
- Journal Title
  
  British Journal of Ophthalmology
  
  Volume: 97 Issue: 3 Pages: 362-366
- DOI
  10.1136/bjophthalmol-2012-302631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659816
[Journal Article] Surface chemistry study of the interactions of hyaluronic acid and benzalkonium chloride with meibomian and corneal cell lipids2013
- Author(s)
  Georgiev Gas, Yokoi N, Ivanova S, Dimitrov T, Andreev K, Krastevd R, Lalchev Z
- Journal Title
  
  Soft Matter
  
  Volume: 9 Issue: 45 Pages: 10841-10856
- DOI
  10.1039/c3sm51849c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] Development and Validation of the Dry Eye-Related Quality-of-Life Score Questionnaire2013
- Author(s)
  Sakane Y, Yamaguchi M, Yokoi N, Uchino M, Dogru M, Oishi T, Ohashi Y, Ohashi Y
- Journal Title
  
  ＪAMA Ophthalmology
  
  Volume: 131 Issue: 10 Pages: 1331-1338
- DOI
  10.1001/jamaophthalmol.2013.4503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462728
[Journal Article] A solute gradient in the tear meniscus. II. A Hypothesis to explain Marx's line2011
- Author(s)
  Bron AJ, Yokoi N, Gaffney EA, Tiffany JM.
- Journal Title
  
  Ocul Surf
  
  Volume: 9 Pages: 92-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] The international workshop on meibomian gland dysfunction : report of the diagnosis subcommittee2011
- Author(s)
  Tomlinson A, Bron AJ, Korb DR, Amano S, Paugh JR, Pearce ET, Yee R, Yokoi N, Arita R, Dogru M
- Journal Title
  
  Invest Ophthalmol Vis.Sci.
  
  Volume: 52 Pages: 2006-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] A solute gradient in the tear meniscus. I. A Hypothesis to explain Marx's line2011
- Author(s)
  Bron AJ, Yokoi N, Gaffney EA, Tiffany JM.
- Journal Title
  
  Ocul Surf
  
  Volume: 9 Pages: 70-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] 涙液の液層と油層の密接な関係2010
- Author(s)
  横井則彦, Georgi As Georgiev
- Journal Title
  
  眼科
  
  Volume: 52 Pages: 1763-1770
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] A mass and solute balance model for tear volume and osmolarity in The normal and the dry eye2010
- Author(s)
  Gaffney E, Tiffany JM, Yokoi N, Bron AJ
- Journal Title
  
  Prog. Retina and Eye Res 29
  
  Pages: 59-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] Predicted phenotypes of dry eye : Proposed consequences of its natural history2009
- Author(s)
  Bron AJ, Yokoi N, Gaffney E, Tiffany JM
- Journal Title
  
  Ocul Surf 7
  
  Pages: 78-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659402
[Journal Article] Human conjunctival epithelial cells express functional Toll-like receptor52008
- Author(s)
  Kojima K, Ueta M, Hamuro J, Hozono Y, Kawasaki S, Yokoi N, Kinoshita S
- Journal Title
  
  Br J Ophthalmol 92
  
  Pages: 411-416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive2008
- Author(s)
  Takaoka M, Nakamura T, Sugai H, Bentley AJ, Nakajima N, Fullwood NJ, Yokoi N, Hyon SH, Kinoshita S
- Journal Title
  
  Biomaterials 29
  
  Pages: 2923-2931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Rheology of tear film lipid layer spread in normal and aqueous tear deficient dry eyes.2008
- Author(s)
  Yokoi N., et al
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 5319-5324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] High-affinity IgE receptor-s chain expression in human mast cells2008
- Author(s)
  Matsuda A, Okayama Y, Ebinhara N, Yokoi N, Gao P, Hamuro J, Hopkin JMKinoshita S.
- Journal Title
  
  J. Immunol. Methods 336
  
  Pages: 229-234
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Surgery of the conjunctiva2008
- Author(s)
  Yokoi N, Inatomi T, Kinoshita S.
- Journal Title
  
  Dev Ophthalmol 41
  
  Pages: 138-58
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Rheology of tear film lipid layer spread in normal and aqueous tear deficient dry eyes2008
- Author(s)
  Yokoi N, Yamada H, Mizukusa Y, Bron AJ, Tiffany JM, Kato T, Kinoshita S.
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(12)
  
  Pages: 5319-5324
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Methodologies to diagnose and monitor dry eye disease: Report of the diagnostic methodology subcommittee of the international dry eye workshop2007
- Author(s)
  Bron AJ, Abelson MB, Ousler G, Pearce E, Tomlinson A, Yokoi N, Smith JA, Begley C, Caffery B, Nichols K, Schaumberg D, Schein O, Calonge M, Baudouin C, Goto E, Grus F, Paugh J
- Journal Title
  
  Ocul Surf 5
  
  Pages: 108-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] A newly-developed video-meibography system featuring anewly-designed probe2007
- Author(s)
  Yokoi N, Komuro A, YamK, Kinoshita S.
- Journal Title
  
  Jpn J Ophthalmol 51(1)
  
  Pages: 53-56
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] A new grading system for the evaluation of chronic ocular manifestations in patients witStevens-Johnson syndrome2007
- Author(s)
  Sotozono C, Ang LPK, Koizumi N,Higashihara H, Ueta M, Inatomi T,Yokoi N, Kaido M, Murato D, ShimazakJ, Tsubota K, Yamada M, Kinoshia S.
- Journal Title
  
  Ophthalmology 114(7)
  
  Pages: 1294-1302
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Methodologies to diagnose and monitor dry eye disease : Reportthe diagnostic methodology subcommittee of the internatdry eye workshop (2007)2007
- Author(s)
  Bron AJ, Abelson MB, E, Tomlinson A, Yokoi N, Smith JA, Begley C, Caffery B, Nichols K, Schaumberg D, Schein O, Calonge MBaudouin C, Goto E, Grus F, Paugh J.
- Journal Title
  
  Ocul Surf 5(2)
  
  Pages: 108-152
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Hyperexpression of the high-affinity IgE receptor-β chain in chronic allergic keratoconjunctivitis
- Author(s)
  Matsuda A, Okayama Y, Ebihara N, Yokoi N, Hamuro J, Walls AF, Ra C, Hopkin JM, Kinoshita S.
- Journal Title
  
  Invest Ophthalmol Vis Sci (in press)
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Predicted phenotypes of dry eye : Proposed consequences of its natural history
- Author(s)
  Bron AJ, Yokoi N, Gaffney Eamonn, Tiffany JM.
- Journal Title
  
  Ocular Surface (in press)
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] A mass and solute balance model for tear volume and osmolarity in the normal and the dry eye prog
- Author(s)
  Gaffney Eamonn, Tiffany JM, Yokoi N, Bron AJ
- Journal Title
  
  Retina and Eye Res (in press)
- Data Source
  KAKENHI-PROJECT-19592034
[Journal Article] Filament in filamentary keratitis
- Author(s)
  Tanioka H, Yokoi N, Komuro A, Shimamoto T, Kawasaki S, Matsuda A, Kinoshita S.
- Journal Title
  
  Invest Ophthalmol Vis Sci (in press)
- Data Source
  KAKENHI-PROJECT-19592034
[Patent] ドライアイ分類に関する方法及びそれを用いた眼科装置、並びに学習器2021
- Inventor(s)
  横井則彦、川井　淳、吉岡　玲二、吉田　健一、山本　大地
- Industrial Property Rights Holder
  京都公立大学法人、株式会社レクザム
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-064437
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K09794
[Patent] 眼科装置2009
- Inventor(s)
  横井則彦、木下茂、水草豊
- Industrial Property Rights Holder
  横井則彦、木下茂、水草豊
- Industrial Property Number
  2010-018380
- Filing Date
  2009-01-22
- Data Source
  KAKENHI-PROJECT-21659402
[Presentation] AI-Assisted Tear Film Oriented Diagnosis (AI-Assisted TFOD)2024
- Author(s)
  Norihiko Yokoi
- Organizer
  The 39th Asia-Pacific Academy of Ophthalmology Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] Recent Advancements of TFOD2024
- Author(s)
  Norihiko Yokoi
- Organizer
  Asia Dry Eye Summit 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] シェーグレン症候群に伴うドライアイ　当科における診断・治療の現状と進歩2023
- Author(s)
  横井則彦
- Organizer
  第31回日本シェーグレン症候群学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] ドライアイ診療最前線2023
- Author(s)
  横井則彦
- Organizer
  角膜カンファランス 2023
- Invited
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] Semantic segmentation を用いた涙液層破壊パターンの可視化2022
- Author(s)
  横井則彦、草田夏樹、加藤弘明、古澤裕貴、外園千恵、吉田健一、吉岡玲二、川井　淳、山本大地、井関裕司
- Organizer
  第3回日本AI学会総会
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] A Novel Dry Eye Classification Method Using Videokeratography and Deep Learning2022
- Author(s)
  Norihiko Yokoi
- Organizer
  角膜カンファランス 2020
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] Videokeratography と深層学習を用いたドライアイのサブタイプ分類2021
- Author(s)
  横井則彦
- Organizer
  第2回日本AI学会総会
- Data Source
  KAKENHI-PROJECT-20K09794
[Presentation] Recent advances in TFOD and TFOT for dry eye2018
- Author(s)
  Yokoi N
- Organizer
  120th Annual Meeting of the Korean Ophthalmological Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Essentials of TFOD and TFOT for dry eye2018
- Author(s)
  Yokoi N
- Organizer
  Vietnam Ophthalmological Society Congress 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] TFOD and TFOT (Tear-film-oriented diagnosis and therapy)2018
- Author(s)
  Yokoi N
- Organizer
  17th Spanish Cornea Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Tear Film Dynamics on the Cornea and the SCL and Their Relation to Dry Eye2017
- Author(s)
  Yokoi N
- Organizer
  Collaborative Meeting School of Optometry, Department of Optics and Spectroscopy, St. Kliment Ohdriski University of Sofia, Sofia, Bulgaria
- Invited
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Tear Film Dynamics on the Cornea and the SCL and Their Relation to Dry Eye2017
- Author(s)
  Yokoi N
- Organizer
  Collaborative Meeting Department of Biomedical Engineering and the Optics and Photonics, Wroclaw University of Science and Technology, Wroclaw, Poland
- Invited
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Rethinking of the Function of TFLL and the Possible Effect of Cationic Emulsion Eye Drops on the TFLL2016
- Author(s)
  Yokoi N
- Organizer
  Asia Dry Eye Summit 2016
- Place of Presentation
  Xiamen, China
- Year and Date
  2016-11-18
- Invited
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Surface interactions of cationicnanoemulsions with human meibum films2016
- Author(s)
  Daull P, Yokoi N, Nencheva Y, Georgiev GAs,
- Organizer
  8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance
- Place of Presentation
  Montpellier, France
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Diagnosis of dry eye based on tear dynamics2016
- Author(s)
  Yokoi N
- Organizer
  Autumn Scientific Meeting of the Taiwan Academy of Ophthalmology
- Place of Presentation
  Taipei，Taiwan
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] Relationship between fluorescein breakup patterns and clinical manifestations in dry eye2016
- Author(s)
  Yokoi N, Georgiev GAs, Kato, Komuro A, Sonomura Y, Sotozono C, Tsubota T, Kinoshita S
- Organizer
  8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance
- Place of Presentation
  Montpellier, France
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11269
[Presentation] The pre-corneal fluid shell. what is the effect of drop instillation?2015
- Author(s)
  Bron AJ, Yokoi N, Yang Z, Georgiev GA
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Denver, U.S.A.
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Relationship between lid-wiper epitheliopathy, tear abnormalities, and blink in dry-eye patients2015
- Author(s)
  Kato H, Yokoi N, Niu M, Sakai R, Watanabe A, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Denver, U.S.A
- Year and Date
  2015-05-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Alteration of tear-film break-up patterns and its impact on eye dryness after long-hours driving-related work: Tokyo study2015
- Author(s)
  Yokoi N, Kawashima M, Kato H, Uchino M, Uchino Y, Dogru M, Kaido M, Tsubota K, Kinoshita S
- Organizer
  American Academy of Ophthalmology
- Place of Presentation
  Las Vegas, U.S.A.
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Impact of membrane associated mucin and diquafosolon the wettability of human corneal epithelium cell lines2015
- Author(s)
  Georgiev GA, Yokoi N, Eftimov P, Stefanova-Eftimova N, Ivanova S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Denver, U.S.A.
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Effect of punctal occlusion on aqueous tear deficient dry eye evaluated from tear film stability and blink-related friction2015
- Author(s)
  Yokoi N, Niu, M, Kato, H, Sakai R, Komuro A, Sonomura Y, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Denver, U.S.A.
- Year and Date
  2015-05-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] The comparison of 3 different methods used for the evaluation of precorneal tear film breakup time2014
- Author(s)
  Niu M, Yokoi N, Kato H, Sakai R, Komuro A, Sonomura Y, Koizumi N, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Orlando, USA
- Year and Date
  2014-05-05
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Investigation of surface properties of films of human meibum from normal eyes and from eyes with meibomian gland dysfunction2014
- Author(s)
  Georgiev GAs, Yokoi N, Ivanova Slavyana, Tonchev V, Krastev R, Lalchev Z
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Orlando, USA
- Year and Date
  2014-05-05
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Investigation of the difference in clinical manifestations in different patterns of tear film breakup2014
- Author(s)
  Yokoi N, Kato H, Sakai R, Georgiev Gas, Shigeru Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Orlando, USA
- Year and Date
  2014-05-05
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] 眼窩外涙腺摘出ドライアイマウスモデルにおける涙液中caspase-1 非依存的IL-1βの増加2012
- Author(s)
  篠宮克彦、上田真由美、小堀麻紀、中西憲司、横井則彦、木下茂
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京都東京国際フォーラム
- Year and Date
  2012-04-05
- Data Source
  KAKENHI-PROJECT-23659816
[Presentation] Usefulness of a dry-eye mouse model produced by exorbital lacrimal gland excision and analysis of the increase of caspase-1 independent IL-1beta in the tear fluid of those mice2012
- Author(s)
  Katsuhiko Shinomiya, Mayumi Ueta, Maki Kobori, Kenji Nakanishi, Norihiko Yokoi, Shigeru Kinoshita
- Organizer
  ARVO2012
- Place of Presentation
  Greater Fort Lauderdale Broward Country Convention Center, Fort Lauderdale, FL, USA
- Year and Date
  2012-05-07
- Data Source
  KAKENHI-PROJECT-23659816
[Presentation] Possible factors that determine precorneal tear film stability2010
- Author(s)
  Yokoi N, Sakai R, Kinoshita S, Mizukusa Y, Bron AJ, Tiffany JM, Georgiev GAs
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, U.S.A.
- Year and Date
  2010-05-06
- Data Source
  KAKENHI-PROJECT-21659402
[Presentation] Non-invasive and quantitative assessment of pre-corneal tear film2010
- Author(s)
  Yokoi N
- Organizer
  The 2nd Asia Cornea Society Biennial Scientific Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21659402
[Presentation] Effect of punctual occlusion on lipid-layer spread and tear film stability in aqueous tear deficient dry eye2010
- Author(s)
  Yokoi N, Sakai R, Bron AJ, Tiffany JM, Georgiev GAs, Kinoshita S
- Organizer
  6th Internatinal Conference on the Tear Film & Ocular Surface : Basic Science and Clinical Relevance
- Place of Presentation
  Florence, Italy
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21659402
[Presentation] Rheological analysis of tear-film lipid-layer spread and its relationship to tear volume2009
- Author(s)
  Yokoi N
- Organizer
  Solving dry eye An international exchange
- Place of Presentation
  Sydney, Australia
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-21659402
[Presentation] A newly developed biodegradable punctal plug with controlled bFGF release for permanent lacrimal punctal occlusion2008
- Author(s)
  Hori K, Hamuro J, Sotozono C, Kawasaki S, Yokoi N, Ueda H, Tabata Y, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] A new surgery for punctal occlusion2008
- Author(s)
  Yokoi N.
- Organizer
  2008 Japan-Korea Joint Cornea Conference
- Place of Presentation
  Seoul
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] A new surgery for punctal occlusion using fibrous tissue from under the caruncle2008
- Author(s)
  Yokoi N, Komuro A, Nishii M.
- Organizer
  American Academy of Ophthalmology 2008 Joint Meeting with the European Society of Ophthalmology
- Place of Presentation
  Atlanta, USA
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Sex differences in meibomian gland physiology2008
- Author(s)
  Suzuki T, Yokoi N, Komuro A, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Retension of long-acting carteolol alginate ophthalmic solution on the human ocular surface2008
- Author(s)
  Komuro A, Yokoi N, Maruyama K, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-04-28
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Composition of the corneal filament in filamentary keratitis on immunohistochemical examination2008
- Author(s)
  Tanioka H, Yokoi N, Shimamoto T, Komuro A, Kawasaki S, Matsuda M, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-04-28
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Advanced conjunctival surgeries for the improvement of dry eye and dry-eye associated disorders2008
- Author(s)
  Yokoi N.
- Organizer
  World Ophthalmology Congress 2008
- Place of Presentation
  Hong Kong
- Year and Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Clinical compatibility of multipurpose solutions with silicone hydrogel contact lenses2008
- Author(s)
  Yokoi N.
- Organizer
  World Ophthalmology Congress 2008
- Place of Presentation
  Hong Kong
- Year and Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Applicability of a new tear stability analysis system for the screening of dry eye2008
- Author(s)
  Shimamoto T, Yokoi N, Maruyama K, Komuro A, Nishii M, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Long-term results of superior conjunctivochalasis operation for treating superior limbic keratoconjunctivitis2007
- Author(s)
  Komuro A, Yokoi N, Maruyama K, Kinoshita S.
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes : Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] ドライアイにおける涙液油層の動態変化. シンポジウム7新世界ドライアイ診断基準とドライアイ診断における考え方はこう変わった2007
- Author(s)
  横井則彦
- Organizer
  第111回日本眼科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Imprementation of a new questionnaire into the recently revised Japanese dry eye diagnostic criteria2007
- Author(s)
  Ward S, Dogru M, Wakamatsu T, Ebrahim O, Kaido M, Matsumoto Y, Yokoi N, Ueda M, Tsuyama A, Tsubota K.
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes : Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] The cyclic change of Meibomian gland physiology during the menstrual cycle2007
- Author(s)
  Suzuki T, Yokoi N, Komuro A, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-06
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Immunohistochemical investigation of the filament in filamentary keratitis2007
- Author(s)
  Tanioka H, Yokoi N, Komuro A, Shimamoto T, Kawasaki S, Matsuda A, Kinoshita S.
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes : Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] A new interference-based in vitro technique for the wettability assessment of soft contact lenses2007
- Author(s)
  Maruyama K, Yokoi N, Kinoshita S.
- Organizer
  British Contact Lens Association
- Place of Presentation
  Manchester, England
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Development of automated rheological analysis for tear film lipidlayer spread using the cross-correlation method.2007
- Author(s)
  Yokoi N., et al
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-06
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] New interferometric-based in vitro technique applicable to the assessment of wettability of contact lenses2007
- Author(s)
  Maruyama K, Yokoi N, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] The improved surgical technique for conjunctivochalasis2007
- Author(s)
  Sonomura Y, Yokoi N, Komuro A, Nishii M, Inagaki K, Chihara H, Kinoshita S.
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes : Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Development of automated rheological analysis for tear film lipid layer spread using the cross-correlation method2007
- Author(s)
  Yokoi N, Yamada H, Maruyama K, Mizukusa Y, Bron AJ, Tiffany JM, Kinoshita S.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-06
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] A new surgical punctal occlusion using fibrous tissue under the lacrimal caruncle2007
- Author(s)
  Yokoi N, Chihara H, Nishii M, Komuro A, Shimamoto T, Kinoshita S
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes: Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] 関法による涙液油層伸展動態の自動解析法の開発とその臨床応用2007
- Author(s)
  横井則彦、山田英明、木下茂、横井則彦、加藤孝久、水草豊.
- Organizer
  第31回角膜カンファランス・第23回日本角膜移植学会
- Place of Presentation
  宮崎
- Year and Date
  2007-02-09
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] A new surgical punctal occlusion using fibrous tissue under the lacrimal caruncle2007
- Author(s)
  Yokoi N, Chihara H, Nishii M, Komuro A, Shimamoto T, Kinoshita S.
- Organizer
  5th international Conference on the Lacrimal Gland, Tear Film, Ocular Surface and Dry Eye Syndromes : Basic Science and Clinical Relevance
- Place of Presentation
  Taormina, Sicily, Italy
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Evaluation of wettability in MPS by interference-based in vitro techniquea2007
- Author(s)
  Sakai R, Maruyama K, Yokoi N, Kinoshita S.
- Organizer
  British Contact Lens Association
- Place of Presentation
  Manchester, England
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] 涙液油層の動態解析. シンポジウム2前眼部画像診断装置の現況2007
- Author(s)
  横井則彦
- Organizer
  第31回角膜カンファランス・第23回日本角膜移植学会
- Place of Presentation
  宮崎
- Year and Date
  2007-02-11
- Data Source
  KAKENHI-PROJECT-19592034
[Presentation] Confirmation of squalene in tears and sebum and it’s potential function
- Author(s)
  Borchman D, Georgiev G, Yappert MC, Yokoi N
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, U.S.A.
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Evaluation of the validity of the diagnostic criteria for dry eye in Japan using subjective symptoms: Osaka study
- Author(s)
  Yokoi N, Uchino M, Uchino Y, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Tsubota K, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, U.S.A.
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] 眼窩外涙腺摘出ドライアイマウスモデルにおける涙液中caspase-1非依存的IL-1βの増加
- Author(s)
  篠宮克彦、上田真由美、小堀麻紀、中西憲司、横井則彦、木下茂
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-23659816
[Presentation] Is short BUT a different type of dry eye disease, or merely an early stage of aqueous deficiency? Different type. Prime time: TFOS Debates
- Author(s)
  Yokoi N
- Organizer
  7th Internatinal Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance
- Place of Presentation
  Sicily, Italy
- Invited
- Data Source
  KAKENHI-PROJECT-25462728
[Presentation] Usefulness of a dry-eye mouse model produced by exorbital lacrimal gland excision and analysis of the increase of caspase-1 independent IL-1beta in the tear fluid of those mice
- Author(s)
  篠宮克彦、上田真由美、小堀麻紀、中西憲司、横井則彦、木下茂
- Organizer
  ARVO2012
- Place of Presentation
  Greater Fort Lauderdale Broward Country Convention Center (Fort Lauderdale, FL)
- Data Source
  KAKENHI-PROJECT-23659816
[Presentation] Surface chemistry study of the interactions of benzalkonium chloride and hyaluronic acid with meibomian and corneal lipids
- Author(s)
  Georgiev GA, Yokoi N, Ivanova S, Krastev R, Lalchef Z
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, U.S.A.
- Data Source
  KAKENHI-PROJECT-25462728

1. KINOSHITA Shigeru (30116024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KAWASAKI Satoshi (60347458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. MATSUDA Akira (00312348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. SHINOMIYA Katsuhiko (50585289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. UETA Mayumi (60398386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. SUZUKI TOMO (30613236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KITAWAKI Jo (00204925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIRANO Shinya (10181174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKAMATA Akira (00264755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUKUOKA Fukuoka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANIOKA Hidetoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. GEORGI AS GEORGIEV

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HORI Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yokoi Norihiko 横井 則彦

横井 則彦 ヨコイ ノリヒコ

YOKOI Norihiko 横井 則彦

Research Projects

Research Products

Co-Researchers

涙液油層機能を維持する生理活性脂質の応用をめざした基礎研究と臨床基盤の確立Principal Investigator

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Review Section

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Elucidation of the mechanism for the formation and breakup of tear film based on lipid layer dynamics and its clinical applicationPrincipal Investigator

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The basic understanding of biological regulation on meibomian glands and ocular surface via sex steroid hormones

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Demonstration of the Molecular Mechanism of Meibomian Lipids on the Determination of Dynamic Characteristics of the Tear Film Lipid LayerPrincipal Investigator

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The contribution of inflammasome in the pathogenesis of dry eye

Principal Investigator

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涙液油層の動態解析法の開発と涙液油層動態決定因子の探索的研究Principal Investigator

Principal Investigator

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Research Institution

Regeneration of lacrimal grand by the induction of highly-ordered acinus branchingPrincipal Investigator

Principal Investigator

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Basic study of the effects of environmental conditions on tear dynamics using an environmental chamberPrincipal Investigator

Principal Investigator

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Elucidation of pathogenesis of ocular complications associated with atopic dermatitis and elucidation of factors predictive of their occurancePrincipal Investigator

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角膜上皮および内皮バリアー機能の調節機構に関する研究Principal Investigator

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[Book] シェーグレン症候群の診断と治療マニュアル 改定第3版2018

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[Book] 1336専門家による私の治療 2017-18年度版2017

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[Book] マイボーム腺機能不全（MGD）の診断と治療2016

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Total Pages

Publisher

Yokoi Norihiko 横井則彦

横井則彦ヨコイノリヒコ

YOKOI Norihiko 横井則彦

[Book] シェーグレン症候群の診断と治療マニュアル　改定第3版2018

[Book] 角膜疾患　外来でこう診てこう治せ2015

[Book] 前眼部の画像診断　専門医のための眼科診療クオリファイ2014

[Book] ドライアイ　スペシャリストへの道　専門医のための眼科診療クオリファイ2013

[Book] メニスコメトリ、インターフェロメトリ. 今日の眼疾患治療指針第2版2007