WATANABE Masaru 渡辺賢

… Alternative Names

渡辺賢ワタナベマサル

渡邉賢ワタナベマサル

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Researcher Number	60191798
Other IDs
External Links
Affiliation (Current)	2025: 東京都立大学, 人間健康科学研究科, 教授 2025: 東京医科大学, 医学部, その他
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京都立大学, 人間健康科学研究科, 教授 2011 – 2019: 首都大学東京, 人間健康科学研究科, 教授 2015: 首都大学東京, その他の研究科, 教授 2010: Tokyo Medical University, 大学院・人間健康科学研究科, 教授 2002 – 2009: 東京医科大学, 医学部, 講師 … More 2004: Tokyo Medical University, Medicine, Assistant nufessor, 医学部, 講師 1998 – 1999: 東京慈恵会医科大学, 医学部, 講師 1995 – 1996: 東京慈恵会医科大学, 医学部, 講師 1993 – 1995: 東京慈恵会医科大学, 医学部, 助手 1992: 東京慈恵会医科大学, 医科部, 助手 Less
Review Section/Research Field	Principal Investigator General physiology / Neurophysiology and muscle physiology / Basic Section 48020:Physiology-related / General physiology / Neurophysiology and muscle physiology / Circulatory organs internal medicine Except Principal Investigator General physiology / Digestive surgery / General physiology / Cerebral neurosurgery
Keywords	Principal Investigator 平滑筋 / ミオシン / アクチン / 収縮 / スキンド標本 / 収縮タンパク質 / ATP / リモデリング / プロテインホスファターゼ2A / ラッチ … More / X線回折 / 筋フィラメント / NMR / オカダ酸 / 弛緩過程 / プロテインキナーゼC / ミオシン軽鎖キナーゼ / ラッチ機構 / ミオシンアクチン相互作用 / ｘ線回折 / プロテインホスファターゼ２A / Caイオン感受性 / フィラメント構造 / アクチン　ミオシン相互作用 / ミオシン軽鎖リン酸化 / プロテインホスファターゼ / gelsolin / phenoxazine / blebbistatin / skinned preparation / remodeling / actin filaments / smooth muscle / ブレビスタチン / アクチン制御タンパク質 / アクチンフィラメント / 力学応答 / 細胞 / 構造 / 筋収縮フィラメント / Ｘ線回折 / フィラメント / 収縮フィラメント / 硬直 / 弛緩 / 細いフィラメント / 太いフィラメント / 赤道反射 / 筋収縮タンパク質 / 血管攣縮 / 過酸化水 / トロポニン / 冠動脈 / ネレルギー変換機構 / 細胞内微細構造 / サポニン / β-エスシン / α毒素 / ミオシン軽鎖燐酸化 / X線回析 / 生筋標本 / 脊椎動物平滑筋 … More Except Principal Investigator 心筋 / 平滑筋 / 細胞内Mg / マグネシウム / 骨格筋 / 高圧ガス保存 / 肺 / イヌ / ラット / 小腸 / 虚血再灌流障害 / 酸素 / 一酸化炭素 / 高圧ガス保存法 / functional analysis of membrane transprot / cardiac myocytes / molecular cloning / Na-Mg exchange / fluorescent Mg indicator / Mg-tolerant cells / Mg transport / intracellular Mg concentration / Mg耐性 / Na / 交換輸送 / Mg輸送体 / 膜輸送の機能解析 / 心筋細胞 / 分子クローニング / Na-Mg交換輸送 / 蛍光Mg指示薬 / Mg耐性細胞 / Mg汲み出し輸送 / 細胞内遊離Mg濃度 / beta-escin / Fluorescent Ca indicator / Intracellular calcium concentration / Muscle / 螢光カルシウム指示薬 / beta-エスチン / alpha毒素 / カルシウムイオン / 骨格筋細胞 / Ca指示薬 / カルシウム濃度 / 数理モデル / システム解析 / マグネシウム輸送体 / マグネシウム透過チャネル / 細胞内マグネシウム / ATP / 膜輸送 / 膜透過性 / heat shock protein / クロスブリッジ / 熱ショックタンパク質 / 収縮タンパク質 / 攣縮 / 脳血管 / 筋小胞体 / 細胞内pH / 蛍光マグネシウム指示薬 / X線回析 / BDM / 2.3-ブタンジオンモノオキシム / 疲労筋 Less

プロテインホスファターゼ2Aによる平滑筋収縮増強・張力保持促進のメカニズムPrincipal Investigator
- Principal Investigator
  
  渡辺賢
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Tokyo Metropolitan University
Regulatory meachnism of protein phosphatase 2A on smooth muscle mechano-chmical couplingPrincipal Investigator
- Principal Investigator
  
  WATANABE MASARU
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Metropolitan University
The application of high pressure gas preservation method in small intestine transplantation
- Principal Investigator
  
  Hatayama Naoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Aichi Medical University
  Tokyo Medical University
Mechanisms of regulation of actin-myosin interaction induced by remodeling of contractile filaments in living smooth musclePrincipal Investigator
- Principal Investigator
  
  WATANABE MASARU
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tokyo Metropolitan University
Quantitative Evaluation of myofilaments remodeling during relaxation-contraction cycling in smooth muscle cells.Principal Investigator
- Principal Investigator
  
  WATANABE Masaru
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tokyo Medical University
Regulation of intracellular magnesium concentration
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
Regulation of smooth muscle contraction through remodeling of actin filamentsPrincipal Investigator
- Principal Investigator
  
  WATANABE Masaru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tokyo Medical University
脳血管攣縮の新しい治療戦略-血管平滑筋収縮タンパク質の直接制御-
- Principal Investigator
  
  三木保
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Medical University
冠動脈攣縮の新しい治療戦略Principal Investigator
- Principal Investigator
  
  渡辺賢 (渡邉賢)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical University
Identification of magnesium transporter molecules and functional analysis with high temporal/spatial resolution.
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
平滑筋収縮におけるプロティンホスファターゼ2Aの生理的意義Principal Investigator
- Principal Investigator
  
  渡辺賢
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
心筋・平滑筋細胞におけるCa遊離・収縮の細胞内Mgによる制御
- Principal Investigator
  
  小西真人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
血管平滑筋細胞内Mgの変動とその生理的役割の解明
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
β-エスシン濃度変化法を用いたオカダ酸による平滑筋収縮抑制機序の解明Principal Investigator
- Principal Investigator
  
  渡辺賢
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
生きている脊椎動物平滑筋細胞におけるミオシン分子構造・軽鎖燐酸化関係定量化の試みPrincipal Investigator
- Principal Investigator
  
  渡辺賢
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
A Novel Method to Quantify Intracellular Free Calcium Concentration in Muscle Cells with a Fluorescent Indicator.
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  The Jikei University School of Medicine
新しいモデルに基づく筋疲労の研究-短縮中のATP分解速度を中心として-
- Principal Investigator
  
  馬詰良樹
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Jikei University School of Medicine

[Journal Article] Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig.2024
- Author(s)
  Satoko Mihashi, Masaru Watanabe
- Journal Title
  
  The Journal of pHysiological　Sciences
  
  Volume: 74 Issue: 1 Pages: 24-24
- DOI
  10.1186/s12576-024-00918-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06785
[Journal Article] Accelerating effects of blebbistatin on relaxation process of cell membrane permeabilized trachea and taenia cecum from guinea pig2020
- Author(s)
  Mihashi S, Ishida Y, Watanabe M.
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 56 Issue: 0 Pages: 19-28
- DOI
  10.1540/jsmr.56.19
- NAID
  130007836996
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08500
[Journal Article] Inhibitory effects of rubratoxin A, a potent inhibitor of protein phosphatase 2, on the Ca<sup>2+</sup>-dependent contraction of skinned carotid artery from guinea pig2019
- Author(s)
  Yasuyuki NARAKI, Masaru WATANABE, Kousuke TAKEYA
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 55 Issue: 0 Pages: 14-22
- DOI
  10.1540/jsmr.55.14
- NAID
  130007634980
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08500
[Journal Article] Protein phosphatases 1 and 2A and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology2018
- Author(s)
  Takai A, Eto M, Hirano K, Takaya K, Wakimoto T, Watanabe M
- Journal Title
  
  The Jounral of Physiological Sciences
  
  Volume: 68 Issue: 2 Pages: 1-17
- DOI
  10.1007/s12576-017-0577-1
- NAID
  40021443577
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08500
[Journal Article] Blebbistatin, a myosin II inhibitor, suppresses Ca<sup>2+</sup>-induced and “sensitized”-contraction of skinned tracheal muscles from guinea pig2013
- Author(s)
  Watanabe M, Yumoto M.
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 49 Issue: 0 Pages: 89-98
- DOI
  10.1540/jsmr.49.89
- NAID
  130003391240
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500475
[Journal Article] Blebbistatin, a myosin II inhibitor, suppresses contraction and disrupts contractile filaments organization of skinned taeniacecum from guinea pig2010
- Author(s)
  Watanabe M, Yumoto M, Tanaka H, Wang HH, Katayama T, Yoshiyama S, Black J, Thatcher SE, Kohama K.
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 298 Pages: 1118-1126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] A potential role of actin filament polymerization/depolymerization in smooth muscle contraction2010
- Author(s)
  Watanabe M, Ishiwata S, Liou Y-M
- Journal Title
  
  Adaptive Medicine
  
  Volume: 2 Pages: 23-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Blebbistatin, a myosin II inhibitor, suppresses contraction and disrupts contractile filaments organization of skinned taenia cecum from guinea pig2010
- Author(s)
  Watanabe M, Yumoto M, Tanaka H, Wang HH, Katayama T, Yoshiyama S, Black J, Thatcher SE, Kohama K.
- Journal Title
  
  Am J Physiol Cell Physiol 298
  
  Pages: 1118-1126
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Stimulatory effects of arachidonic acid on myosin ATPase activity and contraction of smooth muscle via myosin motor domain.2010
- Author(s)
  Katayama T, Watanabe M, et al
- Journal Title
  
  Am J Physiol Am J Physiol Heart Circ Physiol 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] A potential role of actin filament polymerization/depolymerization in smooth muscle contraction.2010
- Author(s)
  Watanabe M, Ishiwata S, Liou Y-M.
- Journal Title
  
  Adaptive Medicine 2
  
  Pages: 23-28
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Differential effects of an expected actin-tropomyosin binding region of heat shock protein 20 on the relaxation in skinned carotid artery and taenia cecum from guinea pig2009
- Author(s)
  Hashimoto, R., Yumoto, M., Watanabe, M., Konishi, M., Haraoka, J. and Miki, T.
- Journal Title
  
  Journal of Smooth Muscle Research 45
  
  Pages: 63-74
- NAID
  130000860930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] 血管異常収縮の新しい治療戦略:平滑筋収縮タンパク質フィラメント構造と機能からのアプローチ2009
- Author(s)
  渡辺賢, 小比類巻生, 湯本正寿
- Journal Title
  
  日本薬理学雑誌 133
  
  Pages: 130-133
- NAID
  10025740138
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Regulatory mechanism of smooth muscle contraction studied with gelsolin-treated strips of Taenia Caeci in Guinea Pig.2009
- Author(s)
  Liou YM, Watanabe M, Yumoto M, Ishiwata S
- Journal Title
  
  Am J Physiol Cell Physiol 296
  
  Pages: 1024-1033
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] 血管異常収縮の新しい治療戦略 : 平滑筋収縮タンパク質フィラメント構造と機能からのアプローチ2009
- Author(s)
  渡辺賢, 小比類巻生湯本正寿
- Journal Title
  
  日本薬理学雑誌 133
  
  Pages: 130-133
- NAID
  10025740138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] 血管異常収縮の新しい治療戦略 : 平滑筋収縮タンパク質フィラメント構造と機能からのアプローチ2009
- Author(s)
  渡辺賢, 小比類巻生, 湯本正寿
- Journal Title
  
  日本薬理学雑誌 133
  
  Pages: 130-133
- NAID
  10025740138
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Regulatory mechanism of smooth muscle contraction studied with gelsolin-treated strips of Taenia Caeci in Guinea Pig.2009
- Author(s)
  Liou YM, Watanabe M, et al.
- Journal Title
  
  Am J Physiol Cell Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Regulatory mechanism of smooth muscle contraction studied with gelsolin-treated strips of Taenia Caeci in Guinea Pig2009
- Author(s)
  Liou YM, Watanabe M, Yumoto M, Ishiwata S
- Journal Title
  
  Am J Physiol Cell Physiol 296
  
  Pages: 1024-1033
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Mechanisms of the inhibitory effects of a phenoxazine compound, 2-amino-4, 4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one on the contraction of smooth muscles in guinea pig taenia cecum.2007
- Author(s)
  Musha S, Watanabe M, et al.
- Journal Title
  
  Journal of Smooth Muscle Research 43・1(In Press)
- NAID
  110006277704
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500277
[Journal Article] Mechanisms of the inhibitory effects of a phenoxazine compound, 2-amino-4,4α-dihydro-4α-7-dimethyl-3 H-phenoxazine-3-one, on the contraction of the smooth muscle of the guinea pig taenia cecum2007
- Author(s)
  Musha, S., Watanabe, M., Tomoda, A. and Konishi, M.
- Journal Title
  
  Journal of Smooth Muscle Research 43
  
  Pages: 15-24
- NAID
  110006277704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Mechanism of the inhibitory effects of a phenoxazine compound, 2-amino-4,1α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one on the contraction of smooth muscles in guinea pig taenia cecum.2007
- Author(s)
  Musha S, Watanabe M, et al.
- Journal Title
  
  Journal of Smooth Muscle Research 43・1(In Press)
- Data Source
  KAKENHI-PROJECT-17500277
[Journal Article] Effects of hydrogen peroxide on contraction of skinned aorta from guinea pig.2003
- Author(s)
  Sakurai, W., Watanabe, M., Yamashina A., Konishi, M.
- Journal Title
  
  Japanese Journal of Physiology 53
  
  Pages: 471-474
- NAID
  10012733201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Urinary excretion of Magnesium (in Japanese).2002
- Author(s)
  Konishi, M., Watanabe, M., Tashiro, M.
- Journal Title
  
  Journal of Japanese Society for Magnesium Research 52
  
  Pages: 531-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Effects of membrane potential on Na+-dependent Mg2+ extrusion from rat ventricular myocytes.2002
- Author(s)
  Tashiro, M.Pulat Tursun, Miyazaki, T., Watanabe, M., Konishi, M.
- Journal Title
  
  Japanese Journal of Physiology 52
  
  Pages: 541-551
- NAID
  130004435853
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Stimulatory effects of arachidonic acid on myosin ATPase activity and contraction of smooth muscle via myosin motor domain
- Author(s)
  Katayama T, Watanabe M, Tanaka H, Hino M, Miyakawa T, Ohki T, Ye LH, Xie C, Yoshiyama S, Nakamura A, Ishikawa R, Tanokura M, Oiwa K, Kohama K
- Journal Title
  
  Am J Physiol Am J Physiol Heart Circ Physiol 298
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Stimulatory effects of arachidonic acid on myosin ATPase activity and contraction of smooth muscle via myosin motor domain.
- Author(s)
  Katayama T, Watanabe M, Tanaka H, Hino M, Miyakawa T, Ohki T, Ye LH, Xie C, Yoshiyama S, Nakamura A, Ishikawa R, Tanokura M, Oiwa K, Kohama K.
- Journal Title
  
  Am J Physiol Am J Physiol Heart Circ Physiol. 298
- Data Source
  KAKENHI-PROJECT-19500356
[Journal Article] Mechanisms of the inhibitory effects of a phenoxazine compound, 2-amino-4, 4α-dihydro-4α-7-dimethy1-3H-phenoxazine-3-one on the contraction of smooth muscles in guinea pig taenia cecum.
- Author(s)
  Saifuding Musha, Masaru Watanabe, Akio Tomoda, Masato Konishi.
- Journal Title
  
  Jounral of Smooth Muscle Research (in Press)
  
  Pages: 34-1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500277
[Presentation] Inhinitory effects of phorbol-12,13-dibutyrate on relaxation of skinned carotid artery2024
- Author(s)
  Masaru Watanabe, Toshio Kitazawa
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] Dorsomorphin, an AMP kinase inhibitor, inhibits skinned smooth muscle contraction through suppression of myosin light chain phosphorylation2023
- Author(s)
  Masaru　Watanabe
- Organizer
  FAOPS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] Dorsomorphin, an AMP kinase inihibitor,inhibits skinned smooth muscle contraction2023
- Author(s)
  Watanabe M, Mihashi S, Narakai Y, Suma K, Okada M.
- Organizer
  第100回記念日本生理Dorsomorphin, an AMP kinase inihibitor,inhibits skinned smooth muscle contraction学会大会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] Effects of EMD57033, an activator of the actomyosin ATPase activity, on the relaxation process of cell membrane permeabilized carotid artery and taenia cecum from guinea pig.2022
- Author(s)
  Naraki Yasuyuki, Masaru Watanabe
- Organizer
  第99回日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] EMD57033は平滑筋スキンド標本のCa2+ 活性化収縮張力を増加させる2022
- Author(s)
  鈴木祐佳、渡辺　賢
- Organizer
  第64回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] EMD57033 enhance Ca2+-induced contraction of skinned smooth muscle2022
- Author(s)
  Yuka Suzuki, Masaru Watanabe
- Organizer
  第99回日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] Mechanisms of slowing effect of inosine triphosphate on skinned smooth muscle relaxation2022
- Author(s)
  Masaru　Watanabe
- Organizer
  第99回日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] AMP kinase 阻害薬はスキンド平滑筋収縮を抑制する2022
- Author(s)
  渡辺　賢
- Organizer
  第65回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] ミオシン ATPase 活性促進剤 EMD57033 がモルモットスキンド平滑筋弛緩過程に及ぼす影響2022
- Author(s)
  楢木康之、渡辺　賢
- Organizer
  第64回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] オシンATPase 活性促進剤EMD57033 がモルモット頸動脈平滑筋弛緩過程に及ぼす影響2021
- Author(s)
  楢木康之、渡辺　賢
- Organizer
  第６３回日本平滑筋学会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] ヌクレオシド三リン酸の核酸塩基がスキンド平滑筋弛緩に与える影響2021
- Author(s)
  渡辺　賢、大塚早智子
- Organizer
  第６３回日本平滑筋学会
- Data Source
  KAKENHI-PROJECT-21K06785
[Presentation] Natural products induced disruption of actin polymerization modulate mechanical responses of skinned smooth muscle through various pathways.2020
- Author(s)
  Watanabe M.
- Organizer
  第97回日本生理学会大会（誌上開催）
- Data Source
  KAKENHI-PROJECT-16K08500
[Presentation] Regulation of thick and thin filaments organization of smooth muscle contraction2019
- Author(s)
  Masaru WATANABE, Naoya NAKAHARA, Yukisato Ishida
- Organizer
  FAOPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08500
[Presentation] 選択的プロテインホスファターゼ2A阻害薬rubratoxinAはβエスシンスキンド平滑筋収縮の潜時を延長する2018
- Author(s)
  楢木　康之, 渡辺　賢
- Organizer
  第６０回日本平滑筋学会
- Data Source
  KAKENHI-PROJECT-16K08500
[Presentation] Mechanisms of inhibitory effects of protein phosphatase 2A on smooth muscle contraction2017
- Author(s)
  Masaru Watanabe, Kousuke Takeya
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（浜松市）
- Year and Date
  2017-03-30
- Data Source
  KAKENHI-PROJECT-16K08500
[Presentation] Rubratoxin A, a specific protein phosphatase 2A inhibitor, suppresses smooth muscle contraction through myosin light chain phosphorylation dependent and independent pathways2017
- Author(s)
  Watanabe M, Naraki Y, Takeya K
- Organizer
  The 3rd Japan-Taiwan Protein Phspatase Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08500
[Presentation] 低濃度オカダ酸による平滑筋スキンド標本弛緩のメカニズム2016
- Author(s)
  中野　真、渡辺　賢、王　志丹、渡辺康雄
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学医学部（山口県宇部市）
- Year and Date
  2016-08-22
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] 平滑筋収縮におけるプロテインホスファターゼ2Aの役割2016
- Author(s)
  渡辺　賢
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学医学部（山口県宇部市）
- Year and Date
  2016-08-22
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Mechanisms　ofaccelerating　effect　of　protein phosphatase2A inhibitors onsmooth muscle relaxation2016
- Author(s)
  Masaru Watanabe
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] X線連続照射による平滑筋フィラメント構造の攪乱2016
- Author(s)
  坂本麻衣、渡辺　賢、中原直哉
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学医学部（山口県宇部市）
- Year and Date
  2016-08-22
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Regulation of thick and thin filaments organization by smooth muscle myosin2014
- Author(s)
  Watanabe M, Ishida Y, Nakahara N, Taguchi M, Kimura M, Takemori S.
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  鹿児島県鹿児島市（鹿児島大学郡元キャンパス）
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ミオシンＩＩ阻害薬によるスキンド平滑筋弛緩促進のメカニズム2013
- Author(s)
  渡辺　賢
- Organizer
  第55回日本平滑筋学会
- Place of Presentation
  北海道旭川市（大雪クリスタルホール）
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ミオシン阻害薬による平滑筋フィラメント配列の撹乱2013
- Author(s)
  渡辺　賢,他7名
- Organizer
  第1回物構研サイエンスフェスタ
- Place of Presentation
  茨城県つくば市
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Mechanisms of blebbistatin induced smooth muslce relaxation2013
- Author(s)
  Watanabe M, Yamamura S
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京都江戸川区
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Myosin II inhibitors accelerate relaxation of skinned taenia cecum2013
- Author(s)
  Watanabe M, Yamamura S.
- Organizer
  Regulatory Circuits in Cell Motility
- Place of Presentation
  米国ペンシルバニア州フィラデルフィア(Thomas Jefferson Univ)
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] 運動時における消化管運動抑制機構解明の試み2012
- Author(s)
  渡辺　賢,田口美香, 木村雅子, 竹森重
- Organizer
  第67回日本体力医学会大会
- Place of Presentation
  岐阜県岐阜市
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ミオシン阻害薬による平滑筋フィラメント配列の攪乱2012
- Author(s)
  渡辺　賢
- Organizer
  第29回PFシンポジウム
- Place of Presentation
  茨城県つくば市
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ミオシンII阻害薬によるスキンド平滑筋弛緩過程2012
- Author(s)
  渡辺　賢、山村　聡、湯本正寿、中野　真
- Organizer
  第54回日本平滑筋学会総会
- Place of Presentation
  東京都港区
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Accelerating effects of myosin II inhibitors on the relaxation process of skinned taenia cecum from guinea pig2012
- Author(s)
  渡辺　賢
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本市
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] 赤道反射プロフィール解析による平滑筋収縮フィラメント動態解析の試み2012
- Author(s)
  渡辺　賢
- Organizer
  第11回コ・メディカル形態機能学会
- Place of Presentation
  東京都荒川区
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ATP depletion induces disturbance of myofilament lattice structure in smooth muscle cells.2011
- Author(s)
  Watanabe M, et al.
- Organizer
  第88回日本生理学会
- Place of Presentation
  誌上開催(震災のため)
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] 細胞内ATP濃度低下は平滑筋収縮タンパク質フィラメント格子状配列を撹乱する2011
- Author(s)
  渡辺　賢
- Organizer
  第53回日本平滑筋学会総会
- Place of Presentation
  東京都品川区
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Analysis of lattice like arrangement in skinned taenia cecum by using X-ray diffraction technique.2010
- Author(s)
  Watanabe M, et al.
- Organizer
  第87回日本生理学会
- Place of Presentation
  岩手県・盛岡市
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Analysis of lattice like arrangement in skinned taenia cecum by using X-ray diffraction technique.2010
- Author(s)
  渡辺賢, 木村雅子, 田口美香, 竹森重, 石田行知, 湯本正寿, 八木直人
- Organizer
  第87回日本生理学会大会 J Physiol Sci 60 ; S87, 2010
- Place of Presentation
  岩手県盛岡市
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] ATP depletion induces disturbance of myofilament lattice structure in smooth muscle cells.2010
- Author(s)
  渡辺賢, 木村雅子, 田口美香, 竹森重, 石田行知, 湯本正寿, 八木直人
- Organizer
  第88回日本生理学会大会誌上開催(震災のため)抄録集p250
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] X線小角散乱による平滑筋・筋フィラメント格子動態解析の試み(第2報)2010
- Author(s)
  渡辺賢、石田行知、木村雅子、田口美香、竹森重、湯本正寿、山口真紀、八木直人
- Organizer
  第52回日本平滑筋学会総会日本平滑筋学会雑誌14 ; J-31, 2010
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Analysis of lattice like arrangement in skinned smooth muscles by using X-ray diffraction technique.2009
- Author(s)
  渡辺賢, 木村雅子, 田口美香, 石田行知, 湯本正寿, 八木直人, 竹森重
- Organizer
  Satellite symposium of the IUPS 2009 "Post-Genomic Advances in the Physiology of Smooth Muscle. Abstracts p59
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] An X-ray diffraction study on skinned smooth muscles of taenia cecum from guinea pig..2009
- Author(s)
  Watanabe M, et al.
- Organizer
  The 36th Congress of the International Union of Physiological Science.
- Place of Presentation
  京都府京都市
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] An X-ray diffraction study on skinned smooth muscles of taenia cecum from guinea pig.2009
- Author(s)
  渡辺賢, 木村雅子, 田口美香, 石田行知, 湯本正寿, 八木直人, 竹森重
- Organizer
  The 36th Congress of the International Union of Physiological Science.
- Place of Presentation
  京都市
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Analysis of lattice like arrangement in skinned smooth muscles by using X-ray diffraction technique. Satellite symposium of the IUPS 20092009
- Author(s)
  Watanabe M, Kimura M, Taguchi M, Ishida Y, Yumoto M, Yagi N, Takemori S
- Organizer
  Post-Genomic Advances in the Physiology of Smooth Muscle
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Analysis of lattice like arrangement in skinned smooth muscles by using X-ray diffraction technique.2009
- Author(s)
  Watanabe M, et al.(シンポジスト)
- Organizer
  Satellite symposium of the IUPS 2009; Post-Genomic Advances in the Physiology of Smooth Muscle
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] X線回折法による平滑筋細胞収縮フィラメントのリモデリング観察の試み2009
- Author(s)
  渡辺賢
- Organizer
  第50回日本平滑筋学会総会
- Place of Presentation
  青森県・弘前市
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] An X-ray diffraction study on skinned smooth muscles of taenia cecum from guinea pig2009
- Author(s)
  Watanabe M, Kimura M, Taguchi M, Ishida Y, Yumoto M, Yagi N, Takemori S
- Organizer
  The 36th Congress of the International Union of Physiological Science
- Place of Presentation
  京都市
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] 血管異常収縮の新しい治療戦略 : 平滑筋収縮タンパク質フィラメント構造と機能からのアプローチ2008
- Author(s)
  渡辺賢, 小比類巻生, 湯本正寿
- Organizer
  第81回日本薬理学会大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] 1) Role of myofilaments dynamics in smooth muscle excitation-contract ion coupling.2008
- Author(s)
  渡辺賢, (他)
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京都・新宿区
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Role in myofilaments dynamics in smooth muscle excitation-contraction coupling2008
- Author(s)
  Watanabe M, Kobirumaki F, Yumoto M
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京都新宿区
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] 2) An X-ary diffraction study on skinned smooth muscles from guinea pig taenia ccaeci.2008
- Author(s)
  渡辺賢, (他)
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京都・新宿区
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Role in myofilaments dynamics in smooth muscle excitation-contraction coupling.2008
- Author(s)
  渡辺賢, 小比類巻生, 湯本正寿
- Organizer
  第85回日本生理学会大会 J Physiol Sci 58 ; s31, 2008
- Place of Presentation
  東京都新宿区
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] 血管異常収縮の新しい治療戦略:平滑筋収縮タンパク質フィラメント構造と機能からのアプローチ2008
- Author(s)
  渡辺賢、小比類巻生、湯本正寿
- Organizer
  第81回日本薬理学会大会 J Pharmacol Sci 106 ; 34p, 2008
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19500356
[Presentation] Na^+-dependent Mg^<2+> efflux is largely inhibited in deenergized heart cells2006
- Author(s)
  Tashiro, M., Watanabe, M. and Konishi, M.
- Organizer
  11th International Magnesium Symposium
- Place of Presentation
  Mie, Japan
- Year and Date
  2006-10-24
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] ミオシンATPase阻害薬による平滑筋収縮抑制のメカニズム
- Author(s)
  渡辺　賢
- Organizer
  第24回日本病態生理学会大会
- Place of Presentation
  北九州国際会議場（福岡県北九州市）
- Year and Date
  2014-08-09 – 2014-08-11
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] Nucleotide dependence on the accelerating effects of myosin II inhibitors on the smooth muscle.
- Author(s)
  Watanabe　M.
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23500475
[Presentation] ミオシンII阻害薬による平滑筋弛緩促進のメカニズム
- Author(s)
  渡辺　賢
- Organizer
  第56回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（神奈川県横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23500475

1. KONISHI Masato (20138746)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. ISHIDA Yukisato (50092135)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. NAKAYAMA Shinsuke (30192230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HIROSE Kenzo (00292730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOKOYAMA Michiko (20398762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. KIMURA Masako (30328314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. MIYAZAKI Takefuimi (60147212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Hatayama Naoyuki (80534792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 馬詰良樹 (40056990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大野哲生 (30233224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 竹森重 (20179675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高田佳史 (30276927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三木保 (30219604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 橋本孝朗 (60266517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松野直徒 (00231598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 梨井康 (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 内藤宗和 (10384984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 伊藤正裕 (00232471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 平井宗一 (70516054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 竹谷浩介 (20586862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

WATANABE Masaru 渡辺 賢

渡辺 賢 ワタナベ マサル

渡邉 賢 ワタナベ マサル

Research Projects

Research Products

Co-Researchers

プロテインホスファターゼ2Aによる平滑筋収縮増強・張力保持促進のメカニズムPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Regulatory meachnism of protein phosphatase 2A on smooth muscle mechano-chmical couplingPrincipal Investigator

Principal Investigator

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Principal Investigator

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Research Category

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Mechanisms of regulation of actin-myosin interaction induced by remodeling of contractile filaments in living smooth musclePrincipal Investigator

Principal Investigator

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Quantitative Evaluation of myofilaments remodeling during relaxation-contraction cycling in smooth muscle cells.Principal Investigator

Principal Investigator

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Research Institution

Principal Investigator

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Regulation of smooth muscle contraction through remodeling of actin filamentsPrincipal Investigator

Principal Investigator

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Principal Investigator

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冠動脈攣縮の新しい治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

平滑筋収縮におけるプロティンホスファターゼ2Aの生理的意義Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Research Institution

β-エスシン濃度変化法を用いたオカダ酸による平滑筋収縮抑制機序の解明Principal Investigator

Principal Investigator

WATANABE Masaru 渡辺賢

渡辺賢ワタナベマサル

渡邉賢ワタナベマサル

[Journal Article] Blebbistatin, a myosin II inhibitor, suppresses Ca<sup>2+</sup>-induced and “sensitized”-contraction of skinned tracheal muscles from guinea pig2013