FUJIHARA Yoichi 藤原洋一

… Alternative Names

FUJIWARA Yoichi 藤原洋一

藤原洋一フジワラヨウイチ

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Researcher Number	60199396
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009: 国際農林水産業研究センター, 研究員 1992 – 2000: 京都薬科大学, 薬学部, 助手 1990: 京都薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Chemical pharmacy / 医薬分子機能学 Except Principal Investigator Chemical pharmacy / Bioorganic chemistry / 医薬分子機能学 / Irrigation, drainage and rural engineering/Rural planning
Keywords	Principal Investigator Fmoc型固相ペプチド合成 / 構造活性相関 / ジスルフィド結合形成反応 / ソマトスタチン / トリフルオロメタンスルホン酸 / Fmoc型固相合成 / インドール保護基 / ヨウ素酸化法 / エンドセリン-1 / 位置選択的架橋反応 … More / Trp含有シスチンペプチド / シリルクロリドースルホキシド法 / 抗体 / キャリア蛋白 / 抗原決定部位 / ベロ毒素 / 腸管出血性大腸菌 / アンタゴニスト / エンドセリン受容体 / RES-701-1 / メサンギウム細胞 / モノクローナル抗体 / アドレノメデュリン / 誘導体 / 酵素的代謝 / ナトリウム利尿ペプチド … More Except Principal Investigator ペプチド合成 / HIVプロテアーゼ阻害剤 / 基質遷移状態誘導体 / ドラッグデザイン / 酵素阻害剤 / 分子認識 / 酵素阻害剤複合体 / 抗エイズ薬 / HIVプロテアーゼ / エイズ治療薬 / X線結晶構造解析 / Anti-HIV Activity / Enzyme Inhibitor / Peptide Synthesis / Substrate Transition State / AIDS Therapeutics / Molecular Recognition / 抗HIV活性 / 基質遷移状態 / 縮合剤 / 酵素・阻害剤複合体 / 薬剤耐性 / 抗ウイルス薬 / ペプチドミメティック / コンフォメーション解析 / コンフォーメーション解析 / ペプチドミミック / 基質遷移状態概念 / 分子設計 / solid pahse synthesis / 固相合成 / HIV Protease Inhibitor / 薬剤耐性ウイルス / 効率的固相合成法 / キノスタチン-272 / プロテアーゼ阻害剤 / レニン阻害剤 / アスパラギン酸プロテアーゼ / CIP reagent / dolastatin 15 / coupling reaction / デブシペプチド / Nメチルアミノ酸 / 固相上縮合 / CIP試薬 / ドラスタチン15 / 縮合反応 / fibrinogen binding / RGD structure / Heck reaction / intramolecular cyclization / コンビナトリアル合成 / RGD誘導体 / Heck反応 / フィブリノーゲン結合阻害 / RGD構造 / ヘック反応 / 分子内環化反応 / Double Drug / HIV protease inhibitor / HIV protease / thiazoline / dialkyl amino acid / mirabazole / anti-cancer alkaloid / coupling reagent / チアゾリン / ジアルキルアミノ酸 / ミラバゾール / 抗腫瘍アルカロイド / HIV Protease / Prodrug / AIDS / dipeptide / Inhibitor / Protease / エイズ薬 / プロドラッグ / エイズ / ジペプチド / 阻害剤 / プロテアーゼ / Anti-AIDS Drug / Drug Resistant Virus / X-ray Crystallography / Conformational Analysis / Peptide synthesis / Substrate Transition State Analog / Enzyme・Inhibitor Complex / HIV Protease Inhibitors / コンフォメーション / 環境文析 / 国際研究者交流 / トルコ / 安定同位体 / 農業工学 / 水循環 / 土壌汚染 / 水質汚濁 / 環境分析 / 分子モデリング / 抗ATL薬 / HTLVプロテアーゼ阻害剤 / 化学合成 / インスリン / シリルクロリド / 位置選択的形成 / ジスルフィド結合 / ヒトインスリン / リ-ドオプチマイゼーション / HTLV-1プロテアーゼ / ATL治療薬 / 高血圧症治療薬 / ペプチドmimic / HIVプロテア-ゼ / レニン / アスパラギン酸プロテア-ゼ Less

Analysis of the Hydrological Environment in Agricultural Regions Using the Method of Environment Traceability.
- Principal Investigator
  
  WATANABE Tsugihiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Irrigation, drainage and rural engineering/Rural planning
- Research Institution
  Research Institute for Humanity and Nature
シリル化合物によるシスチン含有ペプチドの実用的合成法の開発とその応用Principal Investigator
- Principal Investigator
  
  藤原洋一
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
薬剤耐性HIVと変異プロテアーゼの機能解析によるウイルス病原性の分子機構解明-HIVと人類の共生をめざして-
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto Pharmaceutical University
Study on strategy for AIDS drugs against mutant viruses
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO PHARMACEUTICAL UNIVERSITY
Intramolecularcyclization by solid-phase olefination and its application to combinatorial synthesis
- Principal Investigator
  
  AKAJI Kenichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
  Kyoto Pharmaceutical University
Convergent synthesis and SAR of dolastatin 15 by solid phase coupling
- Principal Investigator
  
  AKAJI Kenichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
  Kyoto Pharmaceutical University
腸管出血性大腸菌O157ベロ毒素の関連ペプチドの合成及びその免疫化学的研究Principal Investigator
- Principal Investigator
  
  藤原洋一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto Pharmaceutical University
Molecular design of HIV protease inhibitors restricted to active conformation
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO PHARMACEUTICAL UNIVERSITY
プロテアーゼ・阻害剤複合体の構造解析に基づく阻害剤の構造活性相関研究
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
新規エンドセリンBタイプレセプターアンタゴニストの合成及びその構造活性相関研究Principal Investigator
- Principal Investigator
  
  藤原洋一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
薬剤耐性HIVと変異プロテアーゼの機能解析によるウイルス病原性の分子機構解明
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto Pharmaceutical University
Joint Study on AIDS Drug Based on HIV Protease
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO PHARMACEUTICAL UNIVERSITY
Convergent Synthesis of Anti-Cancer Alkaloid, Mirabazols, using a New Coupling Reagent
- Principal Investigator
  
  AKAJI Kenichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
プロテアーゼ・阻害剤複合体の構造解析に基づく阻害剤の構造活性相関研究
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
新規血圧調整因子アドレノメデュリン関連ペプチドの合成及びその構造活性相関研究Principal Investigator
- Principal Investigator
  
  藤原洋一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Molecular design of AIDS therapeutics based on molecular recognition of enzymes.
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto Pharmaceutical University
Development of Low Molecular Weight HIV Protease Inhibitor for Oral Use
- Principal Investigator
  
  AKAJI Kenichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
プロテアーゼ・阻害剤複合体の構造解析に基づく阻害剤の構造活性相関研究
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
ATL治療薬をめざしたHTLV-1プロテアーゼ阻害剤のデザイン
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
酵素的代謝に安定な心房性ナトリウム利尿ペプチド誘導体の合成研究Principal Investigator
- Principal Investigator
  
  藤原洋一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
ATL治療薬をめざしたHTLV-1プロテアーゼ阻害剤のデザイン
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Pharmaceutical University
アスパラギン酸プロテアーゼの基質遷移状態概念に基づく医薬品の分子設計
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto Pharmaceutical University
位置選択的架橋反応を用いるヒトインスリンの高効率合成
- Principal Investigator
  
  赤路健一
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
アスパラギン酸プロテアーゼの基質遷移状態概念に基づく阻害剤の分子設計と合成研究
- Principal Investigator
  
  木曽良明
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
アスパラギン酸プロテア-ゼの基質遷移状態概念に基づく阻害剤の分子設計と合成研究
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Pharmaceutical University

All 2009 2008 2007

All Journal Article Presentation Book

[Book] Adapting to climate change on the water resources systems of the Seyhan River Basin in Turkey, From Headwaters to the Ocean: Hydrological Changes and Watershed Management", Taylor and Francis2009
- Author(s)
  Fujihara, Y., Watanabe, T., Nagano, T., Tanaka, K., Kojiri, T., M. Taniguchi, W. C. Burnttt, Y. Fukushima, M. Haigh, Y. Umezawa
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] Adapting to climate change on the water resources systems of the Seyhan River Basin in Turkey. M. Taniguchi, W.C. Burnttt, Y. Fukushima, M. Haigh & Y. Umezawa (Eds.) "From Headwaters to the Ocean : Hydrological Changes and Watershed Management"2009
- Author(s)
  Fujihara, Y., Watanabe, T., Nagano, T., Tanaka, K., Kojiri, T.
- Journal Title
  
  Taylor and Francis
  
  Pages: 257-264
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] Modeling interaction of fluid and salt in an apuifer/lagoon system2009
- Author(s)
  Fujinawa, K., Iba, T., Fujihara, Y., Watanabe, T.
- Journal Title
  
  Groundwater Vol.47,No.1
  
  Pages: 35-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] 気候モデル・ダウンスケーリング手法・水文モデルによる温暖化影響評価の不確実性について2008
- Author(s)
  藤原洋一・田中賢治・渡邉紹裕・長野宇規・小尻利治
- Journal Title
  
  応用水文 No.20
  
  Pages: 44-53
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] GCMs・ダウンスケーリング・水文モデルに起因する温暖化影響評価の不確実性2008
- Author(s)
  藤原洋一・田中賢治・渡邉紹裕・小尻利治
- Journal Title
  
  土木学会水工学論文集 Vol.52
  
  Pages: 373-378
- NAID
  130004044041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] Assessing the Impact of Climate Change on the Surface Energy and Water Balance of the Seyhan River Basin Turky, Proc, of 4th intl. Conf. on Water Resources and Environment Research2008
- Author(s)
  Tanaka, K., Y. Fujihara, T. Kojiri
- Journal Title
  
  Proc, of 4th intl. Conf.
  
  Pages: 1180-1189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] GCMs・ダウンスケーリング・水文モデルに起因する温暖化影響評価の不確実性2008
- Author(s)
  藤原洋一
- Journal Title
  
  水工学論文集 52
  
  Pages: 373-378
- NAID
  130004044041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] An inverse-modelling approach to assess the impacts of climate change in the Seyhan River basin, Turkey2008
- Author(s)
  Fujihara, Yoichi
- Journal Title
  
  Hydrological Sciences Journal 53(6)
  
  Pages: 1121-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] 気候モデル・ダウンスケーリング手法・水文モデルによる温暖化影響評価の不確実性について2008
- Author(s)
  藤原洋一
- Journal Title
  
  応用水文 20
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] Assessing the Impacts of Climate Change on the Water Resources of the Seyhan River Basin in Turkey: Use of Dynamically Downscaled Data for Hydrologic Simulations2008
- Author(s)
  Fujihara, Y., K. Tanaka, T. Watanabe, T. Nagano, T. Kojiri
- Journal Title
  
  Journal of Hydrology Vol.353,No.1-2
  
  Pages: 33-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] An inverse-modelling approach to assess the impacts of climate change in the Seyhan River basin, Turkey2008
- Author(s)
  Fujihara, Y., S.P. Simonovic, F. Topaloglu, K. Tanaka, T. Watanabe
- Journal Title
  
  Hydrological Sciences Journal Vol.53,No.6
  
  Pages: 1121-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Journal Article] Climate Change and Alternative Cropping Patterns in Lower Seyhan Irrigation Project: A Regional Simulation Analysis, Journal of Rural Economics2007
- Author(s)
  Umetsu, C., K. Palanisami, Z. Coskun, S. Donma, T. Nagano, Y. Fujihara, K. Tanaka
- Journal Title
  
  Special Issue
  
  Pages: 567-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] Climate change and alternative cropping patterns in lower Seyhan irrigation project : a regional simulation analysis with MRI-CGCM and CCSR-CGCM2009
- Author(s)
  Umetsu, Chieko, K. Palanisami, Ziya Coskun, Sevgi Donma, Takanori Nagano, Yoichi Fujihara, Kenji Tanaka
- Organizer
  The IARU International Scientific Congress "Climate Change : Global Risks, Challenges and Decisions"
- Place of Presentation
  コペンハーゲン(デンマーク)
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] 安定同位体を用いた灌漑農地の環境評価2008
- Author(s)
  久米崇, 長野宇規, 星川圭介, 藤原洋一, 中野孝教, 渡邉紹裕
- Organizer
  農業農村工学会大会講演会
- Place of Presentation
  秋田県立大学
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] GCMs・ダウンスケーリング・水文モデルに起因する温暖化影響評価の不確実性2008
- Author(s)
  藤原洋一
- Organizer
  水工学講演会
- Place of Presentation
  広島大学
- Year and Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] 温暖化がセイハン川流域の水資源に及ぼす影響評価2007
- Author(s)
  藤原洋一
- Organizer
  農業農村工学会
- Place of Presentation
  島根県松江市
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] 温暖化がセイハン川流域の水資源に及ぼす影響評価2007
- Author(s)
  藤原洋一
- Organizer
  農業農村工学会
- Place of Presentation
  島根大学
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19208022
[Presentation] 気候モデル・ダウンスケーリング手法・水文モデルによる温暖化影響評価の不確実性について2007
- Author(s)
  藤原洋一
- Organizer
  水文・水環境研究部会シンポジウム
- Place of Presentation
  岡山大学
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19208022

1. AKAJI Kenichi (60142296)

# of Collaborated Projects: 17 results

# of Collaborated Products: 0 results
2. KIMURA Tooru (70204980)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
3. KISO Yoshiaki (40089107)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
4. KOBAYASHI Yuji (20127228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMAZAKI Toshimasa

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. WATANABE Tsugihiro (50175105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKANO Takanori (20155782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. UMETSU Chieko (40294251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FUJINAWA Katsuyuki (00219031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NAKAYAMA Mikiyasu (10217945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGANO Takanori (70462207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. TANAKA Kenji (30283625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. KUME Takashi (80390714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. HOSHIKAWA Keisuke (20414039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KOSAKI Takashi (00144345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TANAKA Yukio (90463893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
17. HAYASHI Yoshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. LANGNER Andreas

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. UYAR Aysun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 芝井隆

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小寺昭彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. AKCA Erhan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KAPUR Selim

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. BERBERGLU Suha

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. DONMA Sevgi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. BUYUK Gokuhan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. USSERY Micha

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TORCHIA Denn

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. YARCHOAN Rob

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 満屋裕明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 三本勤

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 渡辺紹裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

FUJIHARA Yoichi 藤原 洋一

FUJIWARA Yoichi 藤原 洋一

藤原 洋一 フジワラ ヨウイチ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シリル化合物によるシスチン含有ペプチドの実用的合成法の開発とその応用Principal Investigator

Principal Investigator

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腸管出血性大腸菌O157ベロ毒素の関連ペプチドの合成及びその免疫化学的研究Principal Investigator

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新規エンドセリンBタイプレセプターアンタゴニストの合成及びその構造活性相関研究Principal Investigator

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新規血圧調整因子アドレノメデュリン関連ペプチドの合成及びその構造活性相関研究Principal Investigator

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FUJIHARA Yoichi 藤原洋一

FUJIWARA Yoichi 藤原洋一

藤原洋一フジワラヨウイチ